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Written By ,
Reviewed By Sunny S , MBBS

Manufacturer/Marketer :

Consume Type :

Oral

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About Noxitef-TZ Tablet 10's

Noxitef-TZ Tablet 10's is an antibiotic medication primarily used to treat diarrhoea, dysentery and stomach infections. Dysentery is an intestinal infection generally lasting for three to seven days, causing severe diarrhoea with blood. Diarrhoea is a condition in which bowel movements are too frequent, leading to loose, watery stools. Acute diarrhoea is a common problem and generally lasts for one or two days, whereas chronic diarrhoea lasts four weeks.

Noxitef-TZ Tablet 10's is a combination of two antibiotics, Norfloxacin and Tinidazole, primarily taken to treat diarrhoea, dysentery, and severe stomach infections. Norfloxacin helps by preventing the bacterial cells from dividing and hence killing the bacteria. Tinidazole kills parasites that cause infections by damaging their DNA. Both of them help effectively treat the infection by killing the bacteria as they are bactericidal in nature.

Noxitef-TZ Tablet 10's can be taken with or without food. For best results, take Noxitef-TZ Tablet 10's as advised by your doctor. Do not chew, crush, or break it. Like all medicines, Noxitef-TZ Tablet 10's may cause side effects, although not everybody gets them. Some side effects of Noxitef-TZ Tablet 10's include nausea, dryness of mouth, stomach upset, headache. Most of these side effects of Noxitef-TZ Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Do not take Noxitef-TZ Tablet 10's if you are allergic to Noxitef-TZ Tablet 10's, tinidazole, norfloxacin, or any of its ingredients as it can lead to abnormal neurological signs (such as dizziness, vertigo, difficulty in controlling movements). Norfloxacin present in Noxitef-TZ Tablet 10's is known to cause tendon rupture, so be cautious while taking Noxitef-TZ Tablet 10's. In patients having myasthenia gravis (muscle weakness), Noxitef-TZ Tablet 10's should not be taken as it is known to worsen your condition further. Noxitef-TZ Tablet 10's should not be taken if you are pregnant or breastfeeding. Do not start using a new medication without telling your doctor. Diarrhoea can cause dehydration, so please increase the intake of fluids. If you have constipation or have blood in stools, do not take Noxitef-TZ Tablet 10's. Consumption of alcohol, along with Noxitef-TZ Tablet 10's, can cause stomach irritation and increased drowsiness.

Uses of Noxitef-TZ Tablet 10's

Diarrhoea, Dysentry, Stomach infections

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Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush, break or chew it. Syrup/Suspension/Drops: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Key Benefits

Noxitef-TZ Tablet 10's is primarily used to treat dysentery, diarrhoea, and upset stomach. Additionally, when Noxitef-TZ Tablet 10's is taken as a course, as directed by a doctor, it helps eradicate and prevent the return of infections caused due to microorganisms responsible for digestive tract infections. It is a combination of two antibiotics, norfloxacin, and tinidazole. Noxitef-TZ Tablet 10's plays a vital role in treating diarrhoea and dysentery. Norfloxacin helps by preventing the bacterial cells from dividing and hence killing the bacteria. Tinidazole kills parasites that cause infections by damaging their DNA. Both of them help effectively treat the infection by killing the bacteria as they are bactericidal in nature.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Noxitef-TZ Tablet 10's if you are allergic to Noxitef-TZ Tablet 10's, tinidazole, norfloxacin, or any of its ingredients. Inform your doctor if you have any kidney or liver problem, any neurologic problem, Norfloxacin present in Noxitef-TZ Tablet 10's is known to cause tendon rupture, so be cautious while taking Noxitef-TZ Tablet 10's. In patients having myasthenia gravis (muscle weakness), Noxitef-TZ Tablet 10's should not be taken as it is known to worsen your condition further. Noxitef-TZ Tablet 10's should not be taken if you are pregnant or breastfeeding. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Diarrhoea can cause dehydration, so please increase the intake of fluids. If you have constipation or have blood in stools, do not take Noxitef-TZ Tablet 10's. Consumption of alcohol, along with Noxitef-TZ Tablet 10's, can cause stomach irritation and increased drowsiness.

Drug-Drug Interactions

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NorfloxacinMesoridazine
Critical

Drug-Drug Interactions

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How does the drug interact with Noxitef-TZ Tablet:
Coadministration of Noxitef-TZ Tablet with Sotalol can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Noxitef-TZ Tablet with Sotalol together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
NorfloxacinMesoridazine
Critical
How does the drug interact with Noxitef-TZ Tablet:
Using Mesoridazine together with Noxitef-TZ Tablet can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Mesoridazine with Noxitef-TZ Tablet is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
NorfloxacinBepridil
Critical
How does the drug interact with Noxitef-TZ Tablet:
Using bepridil together with Noxitef-TZ Tablet can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Noxitef-TZ Tablet with Bepridil is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, or a fast or pounding heartbeat. Do not stop using any medications without talking to a doctor.
How does the drug interact with Noxitef-TZ Tablet:
Coadministration of Noxitef-TZ Tablet with Cisapride can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Noxitef-TZ Tablet with Cisapride together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Noxitef-TZ Tablet:
The combination of Amiodarone and Noxitef-TZ Tablet may significantly raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Despite the fact that Amiodarone and Noxitef-TZ Tablet interact, it can be taken if prescribed by a doctor. If you get dizziness, lightheadedness, fainting, or fast or racing heartbeats, consult a doctor. Do not stop taking any medications without visiting a doctor.
How does the drug interact with Noxitef-TZ Tablet:
Coadministration of Noxitef-TZ Tablet with Disopyramide can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Noxitef-TZ Tablet with Disopyramide together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
TinidazoleAmprenavir
Critical
How does the drug interact with Noxitef-TZ Tablet:
Co-administration of Amprenavir and Noxitef-TZ Tablet can increase the risk or severity of developing serious side effects.

How to manage the interaction:
Co-administration of Amprenavir and Noxitef-TZ Tablet is generally avoided, as it can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms like flushing, severe headache, difficulty breathing, nausea, vomiting, sweating, thirst, chest pain, rapid heartbeat, palpitation, excessive sweating, dizziness, lightheadedness, blurred vision, or confusion. Rarely, more severe reactions may include unconsciousness or convulsions, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Noxitef-TZ Tablet:
Coadministration of Noxitef-TZ Tablet and hydrocortisone can increase the risk or severity of tendinitis (inflammation of the tendons attached to the muscle and bones).

How to manage the interaction:
co-administration of Noxitef-TZ Tablet and hydrocortisone can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like pain, swelling, or inflammation of a tendon area such as the back of the ankle, shoulder, biceps, hand, or thumb, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Noxitef-TZ Tablet:
Coadministration of Noxitef-TZ Tablet with Osimertinib can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Noxitef-TZ Tablet with Osimertinib together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Noxitef-TZ Tablet:
Coadministration of Noxitef-TZ Tablet with Repaglinide may sometimes affect blood glucose levels. Both high blood glucose and, less frequently, low blood glucose have been reported.

How to manage the interaction:
Although there is a possible interaction, Noxitef-TZ Tablet can be taken with Repaglinide if prescribed by the doctor. Consult the prescriber if you experience symptoms such as nervousness, confusion, headache, dizziness, drowsiness, tremors, nausea, hunger, weakness, perspiration, palpitation, rapid heartbeat, increased urination, increased thirst, and increased hunger. Maintaining blood glucose levels is advised. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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NORFLOXACIN-400MG+TINIDAZOLE-600MGCalcium rich foods

Drug-Food Interactions

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NORFLOXACIN-400MG+TINIDAZOLE-600MGCalcium rich foods
Common Foods to Avoid:
Tofu Set With Calcium, Ragi, Seasame Seeds, Kale, Milk, Almonds, Bok Choy, Calcium-Fortified Soy Milk, Cheese, Yogurt

How to manage the interaction:
Consumption of food containing minerals like magnesium, zinc, and calcium reduces the absorption of Tinidazole and Norfloxacin, resulting in reduced medication efficacy in treating infections. It is advised to take Tinidazole and Norfloxacin on an empty stomach and to avoid consuming food or products containing minerals one hour before and 2 hours after consuming Tinidazole and Norfloxacin.

Diet & Lifestyle Advise

  • Antibiotics can alter the useful bacteria in the stomach, which helps indigestion. Therefore, you are advised to take foods rich in probiotics such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto, and cheese.
  • Eat fibre-rich food like whole grains, beans, lentils, berries, broccoli, peas and bananas.
  • Avoid foods rich in calcium, grapefruit and grapefruit juice as they might hinder antibiotic's absorption.
  • Avoid consumption of alcohol to treat your condition effectively.
  • Avoid usage of tobacco.
  • To cure your condition effectually, complete the full course of Noxitef-TZ Tablet 10's even though you find symptomatic relief.

Habit Forming

No

Therapeutic Class

[ANTIBIOTICS]

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Alcohol

Safe if prescribed

Noxitef-TZ Tablet 10's should not be taken along with alcohol as it is known to cause stomach irritation.

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Pregnancy

Consult your doctor

Caution should be exercised, it is advisable to consult a doctor before using it.

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Breast Feeding

Consult your doctor

Noxitef-TZ Tablet 10's does not pass on to the child significantly via breast milk, it is advisable to consult a doctor before using it.

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Driving

Safe if prescribed

Noxitef-TZ Tablet 10's may cause dizziness and vision problems. So, drive only if you are alert.

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Liver

Consult your doctor

Noxitef-TZ Tablet 10's to be taken with caution, especially if you have a history of Liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Consult your doctor

Noxitef-TZ Tablet 10's to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Safe if prescribed

Noxitef-TZ Tablet 10's is not recommended for children below 12 years of age without a doctor's consent. For children above 12 years, the dose to be adjusted and recommended by a child specialist only.

FAQs

Noxitef-TZ Tablet 10's is a combination of two antibiotics, Norfloxacin, and Tinidazole, primarily taken to treat diarrhoea, dysentery, and severe stomach infections. Norfloxacin helps by preventing the bacterial cells from dividing and hence killing the bacteria. Tinidazole kills parasites that cause infections by damaging their DNA. Both of them help effectively treat the infection by killing the bacteria as they are bactericidal in nature.

Yes, Noxitef-TZ Tablet 10's may cause minor skin rashes or reactions. In case you are experiencing skin rashes or any such allergic reactions, consult a doctor and stop taking Noxitef-TZ Tablet 10's.

No, Noxitef-TZ Tablet 10's is a combination of two antibiotic drugs, it helps resolve moderate to severe infections of the stomach. This medicine is not a pain killer. However, completing a full course of Noxitef-TZ Tablet 10's may bring relief to discomfort, and stomach pain caused due to infections.

The use of Noxitef-TZ Tablet 10's is considered to be harmful to patients with known allergy to norfloxacin or tinidazole, or any other excipient present in the medicine. It should preferably be avoided in patients with a history of tendinitis (inflammation of the tendons) or tendon rupture. It is also avoided in patients with some neurological disorders.

No, do not stop taking Noxitef-TZ Tablet 10's even if you feel better as it is an antibiotic medication and a full course of treatment is necessary. For the best advice, consult your doctor and do as advised.

It is recommended not to take dairy products such as milk, yoghurt, and Noxitef-TZ Tablet 10's as they might decrease the effectiveness of Noxitef-TZ Tablet 10's. Please maintain a gap of at least 2 hours between both of them.

Country of origin

India

Manufacturer/Marketer address

Leeford Healthcare Limited , Leo House, Shaheed Bhagat Singh Nagar, Dugri-Dhandra Road, Near Joseph School , Ludhiana-141116.
Other Info - NOX0080

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