Norfloxacin+tinidazole
About
Norfloxacin+tinidazole is an antibiotic medication primarily used to treat diarrhoea, dysentery and stomach infections. Dysentery is an intestinal infection generally lasting for three to seven days, causing severe diarrhoea with blood. Diarrhoea is a condition in which bowel movements are too frequent, leading to loose, watery stools. Acute diarrhoea is a common problem and generally lasts for one or two days, whereas chronic diarrhoea lasts four weeks.
Norfloxacin+tinidazole is a combination of two antibiotics, Norfloxacin and Tinidazole, primarily taken to treat diarrhoea, dysentery, and severe stomach infections. Norfloxacin helps by preventing the bacterial cells from dividing and hence killing the bacteria. Tinidazole kills parasites that cause infections by damaging their DNA. Both of them help effectively treat the infection by killing the bacteria as they are bactericidal in nature.
Norfloxacin+tinidazole can be taken with or without food. For best results, take Norfloxacin+tinidazole as advised by your doctor. Do not chew, crush, or break it. Like all medicines, Norfloxacin+tinidazole may cause side effects, although not everybody gets them. Some side effects of Norfloxacin+tinidazole include nausea, dryness of mouth, stomach upset, headache. Most of these side effects of Norfloxacin+tinidazole do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Do not take Norfloxacin+tinidazole if you are allergic to Norfloxacin+tinidazole, tinidazole, norfloxacin, or any of its ingredients as it can lead to abnormal neurological signs (such as dizziness, vertigo, difficulty in controlling movements). Norfloxacin present in Norfloxacin+tinidazole is known to cause tendon rupture, so be cautious while taking Norfloxacin+tinidazole. In patients having myasthenia gravis (muscle weakness), Norfloxacin+tinidazole should not be taken as it is known to worsen your condition further. Norfloxacin+tinidazole should not be taken if you are pregnant or breastfeeding. Do not start using a new medication without telling your doctor. Diarrhoea can cause dehydration, so please increase the intake of fluids. If you have constipation or have blood in stools, do not take Norfloxacin+tinidazole. Consumption of alcohol, along with Norfloxacin+tinidazole, can cause stomach irritation and increased drowsiness.
Uses of Norfloxacin+tinidazole
Medicinal Benefits
Norfloxacin+tinidazole is primarily used to treat dysentery, diarrhoea, and upset stomach. Additionally, when Norfloxacin+tinidazole is taken as a course, as directed by a doctor, it helps eradicate and prevent the return of infections caused due to microorganisms responsible for digestive tract infections. It is a combination of two antibiotics, norfloxacin, and tinidazole. Norfloxacin+tinidazole plays a vital role in treating diarrhoea and dysentery. Norfloxacin helps by preventing the bacterial cells from dividing and hence killing the bacteria. Tinidazole kills parasites that cause infections by damaging their DNA. Both of them help effectively treat the infection by killing the bacteria as they are bactericidal in nature.
Directions for Use
Storage
Side Effects of Norfloxacin+tinidazole
- Nausea
- Dryness of mouth
- Stomach upset
- Nausea
- Headache
- Metallic taste or change in taste
- Loss of appetite, weakness
- Skin rash or itching
In-Depth Precautions and Warning
Drug Warnings
Do not take Norfloxacin+tinidazole if you are allergic to Norfloxacin+tinidazole, tinidazole, norfloxacin, or any of its ingredients. Inform your doctor if you have any kidney or liver problem, any neurologic problem, Norfloxacin present in Norfloxacin+tinidazole is known to cause tendon rupture, so be cautious while taking Norfloxacin+tinidazole. In patients having myasthenia gravis (muscle weakness), Norfloxacin+tinidazole should not be taken as it is known to worsen your condition further. Norfloxacin+tinidazole should not be taken if you are pregnant or breastfeeding. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Diarrhoea can cause dehydration, so please increase the intake of fluids. If you have constipation or have blood in stools, do not take Norfloxacin+tinidazole. Consumption of alcohol, along with Norfloxacin+tinidazole, can cause stomach irritation and increased drowsiness.
Drug Interactions
Drug-Drug Interaction: Norfloxacin+tinidazole may have interaction with pain killers (aspirin, ibuprofen), anti-coagulant/blood thinner (warfarin), anti-gout (probenecid), antibiotic (azithromycin, sulfamethoxazole, ciprofloxacin, trimethoprim, amoxicillin, metronidazole, nitrofurantoin, erythromycin), calcium supplements (calcium/vitamin D), antidiabetics (Glyburide), antiepileptics (Phenobarbital, Phenytoin) and live vaccines (cholera, typhoid).
Drug-Food Interaction: Norfloxacin+tinidazole is known to interact with multivitamins, caffeine, dairy products, multi-minerals.
Drug-Disease Interaction: Norfloxacin+tinidazole is known to interact if taken along with colitis (inflammation of the colon), CNS disorders, myasthenia gravis (muscle weakness), kidney or liver problems, peripheral neuropathy (nerve damage of brain), QT interval prolongation, history of tendon rupture, neurological disorders, blood dyscrasia (abnormal disease of blood).
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeNorfloxacin+tinidazole should not be taken along with alcohol as it is known to cause stomach irritation.
Pregnancy
cautionCaution should be exercised, it is advisable to consult a doctor before using it.
Breast Feeding
safe if prescribedNorfloxacin+tinidazole does not pass on to the child significantly via breast milk, it is advisable to consult a doctor before using it.
Driving
cautionNorfloxacin+tinidazole may cause dizziness and vision problems. So, drive only if you are alert.
Liver
cautionNorfloxacin+tinidazole to be taken with caution, especially if you have a history of Liver diseases/conditions. The dose may have to be adjusted by your doctor.
Kidney
cautionNorfloxacin+tinidazole to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.
Children
cautionNorfloxacin+tinidazole is not recommended for children below 12 years of age without a doctor's consent. For children above 12 years, the dose to be adjusted and recommended by a child specialist only.
Habit Forming
Diet & Lifestyle Advise
- Antibiotics can alter the useful bacteria in the stomach, which helps indigestion. Therefore, you are advised to take foods rich in probiotics such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto, and cheese.
- Eat fibre-rich food like whole grains, beans, lentils, berries, broccoli, peas and bananas.
- Avoid foods rich in calcium, grapefruit and grapefruit juice as they might hinder antibiotic's absorption.
- Avoid consumption of alcohol to treat your condition effectively.
- Avoid usage of tobacco.
- To cure your condition effectually, complete the full course of Norfloxacin+tinidazole even though you find symptomatic relief.
Special Advise
- Diarrhea can cause dehydration, so please increase the intake of fluids.
- Norfloxacin present in Norfloxacin+tinidazole is known to cause tendon rupture, so be cautious while taking Norfloxacin+tinidazole if you have a tendon rupture history.
- Norfloxacin present in Norfloxacin+tinidazole may cause live bacterial vaccines (such as typhoid vaccine) to not work as well. Do not have any immunizations/vaccinations while using this medication unless your doctor tells you to.
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You must avoid being in the sunlight for too long as Norfloxacin+tinidazole may make you more sensitive to the sun.
Patients Concern
Disease/Condition Glossary
Dysentery: Dysentry is mostly caused by bacterial intestinal infection by the bacteria Shigella, in which there is inflammation in the intestine, particularly the colon. It generally lasts for three to seven days, causing severe diarrhoea with blood.
Diarrhoea: It is a condition in which bowel movements are too frequent, leading to loose, watery stools. Acute diarrhoea is a common problem and generally lasts for one or two days, whereas chronic diarrhoea lasts four weeks.
Bacterial infections: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect our body. Infectious or harmful bacteria can make you sick and reproduce quickly in your body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick. It can target any body part and multiply very quickly. When you get infected with bacteria, you can experience generalized symptoms, like fevers, chills, and fatigue. Bacteria are of various forms comprising commonly of spherical, rod, and spiral-shaped. Bacterial infections vary from minor illnesses like sore throat and ear infections to severe brain infections like meningitis and encephalitis. Anyone can become infected with a bacterial infection. But, people with weak immune systems or taking immunosuppressive medicine are more prone to bacterial infection.
FAQs
Norfloxacin+tinidazole is a combination of two antibiotics, Norfloxacin, and Tinidazole, primarily taken to treat diarrhoea, dysentery, and severe stomach infections. Norfloxacin helps by preventing the bacterial cells from dividing and hence killing the bacteria. Tinidazole kills parasites that cause infections by damaging their DNA. Both of them help effectively treat the infection by killing the bacteria as they are bactericidal in nature.
Yes, Norfloxacin+tinidazole may cause minor skin rashes or reactions. In case you are experiencing skin rashes or any such allergic reactions, consult a doctor and stop taking Norfloxacin+tinidazole.
No, Norfloxacin+tinidazole is a combination of two antibiotic drugs, it helps resolve moderate to severe infections of the stomach. This medicine is not a pain killer. However, completing a full course of Norfloxacin+tinidazole may bring relief to discomfort, and stomach pain caused due to infections.
The use of Norfloxacin+tinidazole is considered to be harmful to patients with known allergy to norfloxacin or tinidazole, or any other excipient present in the medicine. It should preferably be avoided in patients with a history of tendinitis (inflammation of the tendons) or tendon rupture. It is also avoided in patients with some neurological disorders.
No, do not stop taking Norfloxacin+tinidazole even if you feel better as it is an antibiotic medication and a full course of treatment is necessary. For the best advice, consult your doctor and do as advised.
It is recommended not to take dairy products such as milk, yoghurt, and Norfloxacin+tinidazole as they might decrease the effectiveness of Norfloxacin+tinidazole. Please maintain a gap of at least 2 hours between both of them.
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