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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy

About Ondem Injection 10 x 2 ml

Ondem Injection 10 x 2 ml belongs to a class of drugs called antiemetics used to prevent nausea and vomiting during chemotherapy. Nausea is a feeling of uneasiness of the stomach that often comes before vomiting. On the other hand, vomiting is the forcible voluntary or involuntary emptying of stomach contents through the mouth.

Ondem Injection 10 x 2 ml contains Ondansetron which works by blocking the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it prevents nausea and vomiting. 

Ondem Injection 10 x 2 ml will be administered by a healthcare professional. Do not self-administer. In some cases, Ondem Injection 10 x 2 ml may cause headache, constipation, a feeling of warmth or flushing, redness, and irritation at the site of injection. Most of these side effects of Ondem Injection 10 x 2 ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. 

If you are allergic to Ondansetron, Palanosetron, Granisetron, or any other medicines, please tell your doctor. Ondem Injection 10 x 2 ml should be given to children only in doses advised by the doctor based on the child’s body weight or body surface area. If you are pregnant or breastfeeding, must inform your doctor before receiving Ondem Injection 10 x 2 ml .

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Whats That

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Non returnable*
COD available

Online payment accepted

Composition

ONDANSETRON-2MG

Manufacturer/Marketer

Alkem Laboratories Ltd

Consume Type

PARENTERAL

Return Policy

3 Days Returnable

Expires on or after

Apr-24

for this medicine

Uses of Ondem Injection 10 x 2 ml

Prevent nausea and vomiting

Medicinal Benefits

Ondem Injection 10 x 2 ml contains Ondansetron that blocks the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it prevents nausea and vomiting caused by chemotherapy in adults and children and also after surgery. Additionally, Ondem Injection 10 x 2 ml can be used to prevent nausea and vomiting caused by radiotherapy for cancer in adults.

Side Effects of Ondem Injection 10 x 2 ml

  • Headache
  • Constipation
  • A feeling of warmth or flushing
  • Redness and irritation at the site of injection

Directions for Use

Ondem Injection 10 x 2 ml will be administered by a healthcare professional. Do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

If you are allergic to Ondansetron, Palanosetron, Granisetron, or any other medicines, please tell your doctor. Ondem Injection 10 x 2 ml should be given to children only in doses as advised by the doctor based on the child’s body weight or body surface area. Ondem Injection 10 x 2 ml should be used during pregnancy or breastfeeding after consultation with a doctor. If you have problems with levels of sodium, magnesium, and potassium salts in your blood, inform your doctor before taking Ondem Injection 10 x 2 ml . 

Therapeutic Class

ANTIEMETICS

Drug-Drug Interactions

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OndansetronZiprasidone
Critical
OndansetronOlanzapine
Severe

Drug-Drug Interactions

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OndansetronZiprasidone
Critical
How does the drug interact with Ondem Injection 10 x 2 ml :
Taking Ondem Injection 10 x 2 ml with Ziprasidone can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Ondem Injection 10 x 2 ml with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
OndansetronOlanzapine
Severe
How does the drug interact with Ondem Injection 10 x 2 ml :
The combined use of Ondem Injection 10 x 2 ml and Olanzapine can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Ondem Injection 10 x 2 ml and Olanzapine can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OndansetronProcarbazine
Severe
How does the drug interact with Ondem Injection 10 x 2 ml :
When Ondem Injection 10 x 2 ml , is taken with procarbazine it can cause serotonin syndrome. (a condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Co-administration of Ondem Injection 10 x 2 ml along with procarbazine can lead to an interaction, it can be taken if recommended by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, a shaking sensation, incoordination, stomach cramp, nausea, vomiting, and diarrhea, see a doctor. Do not discontinue any medications without a doctor's advice.
OndansetronAmitriptyline
Severe
How does the drug interact with Ondem Injection 10 x 2 ml :
Coadministration of Amitriptyline and Ondem Injection 10 x 2 ml can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Although combining Amitriptyline with Ondem Injection 10 x 2 ml can lead to an interaction, they can be taken if prescribed by a doctor. If you have sudden dizziness, lightheadedness, fainting, confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles, or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea, or fast or rapid heartbeats during therapy, get emergency medical help. Inform a doctor if you have recently taken amitriptyline. Do not discontinue any medication without consulting a doctor.
OndansetronAnagrelide
Severe
How does the drug interact with Ondem Injection 10 x 2 ml :
Taking Ondem Injection 10 x 2 ml with anagrelide increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Co-administration of Ondem Injection 10 x 2 ml alongside anagrelide can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, get medical help immediately. Do not discontinue any medications without a doctor's advice.
OndansetronEletriptan
Severe
How does the drug interact with Ondem Injection 10 x 2 ml :
When Ondem Injection 10 x 2 ml , is taken with eletriptan it can cause serotonin syndrome. (a condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Co-administration of Ondem Injection 10 x 2 ml along with eletriptan can lead to an interaction, it can be taken if recommended by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, a shaking sensation, incoordination, stomach cramp, nausea, vomiting, and diarrhea, see a doctor. Do not discontinue any medications without a doctor's advice.
OndansetronZolmitriptan
Severe
How does the drug interact with Ondem Injection 10 x 2 ml :
When Ondem Injection 10 x 2 ml , is taken with zolmitriptan it can cause serotonin syndrome. (a condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Although taking Ondem Injection 10 x 2 ml along with zolmitriptan can lead to interaction, it can be taken if recommended by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, a shaking sensation, incoordination, stomach cramp, nausea, vomiting, and diarrhea, see a doctor. Do not discontinue any medications without a doctor's advice.
OndansetronNilotinib
Severe
How does the drug interact with Ondem Injection 10 x 2 ml :
Taking Ondem Injection 10 x 2 ml with nilotinib increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Co-administration of Ondem Injection 10 x 2 ml along with nilotinib can result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without a doctor's advice.
OndansetronProtriptyline
Severe
How does the drug interact with Ondem Injection 10 x 2 ml :
When Ondem Injection 10 x 2 ml is taken with protriptyline, it can increase the risk of serotonin syndrome (Serotonin syndrome is a condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Although taking Ondem Injection 10 x 2 ml along with protriptyline can result in an interaction, it can be taken if a doctor has advised it. However, if you have sudden dizziness, lightheadedness, fainting, confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles, or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea, or fast or rapid heartbeats during therapy, consult the doctor. Do not discontinue any medications without a doctor's advice.
OndansetronSumatriptan
Severe
How does the drug interact with Ondem Injection 10 x 2 ml :
Using Ondem Injection 10 x 2 ml together with Sumatriptan might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to severe side effects.

How to manage the interaction:
Co-administration of Ondem Injection 10 x 2 ml along with sumatriptan can lead to an interaction, it should be taken only if recommended by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, a shaking sensation, incoordination, stomach cramp, nausea, vomiting, and diarrhea, see a doctor. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • PHENYTOIN
  • CARBAMAZEPINE
  • RIFAMPICIN
  • ERYTHROMYCIN
  • KETOCONAZOLE
  • TRAMADOL
  • CITALOPRAM
  • FLUOXETINE
  • FLUVOXAMINE
  • PAROXETINE
  • SERTRALINE
  • ESCITALOPRAM
  • DULOXETINE
  • VENLAFAXINE
  • HALOPERIDOL

Diet & Lifestyle Advise

  • Eat a healthy and a low-fat diet, especially in small portions, as it will be easy for digestion. Avoid eating over-sweet food and include more salty food, especially if you have been vomiting.
  • Drink any other liquid at least 30 minutes after eating food. 
  • If the smell of food makes you feel sick (vomit), do not cook food as it may worsen your condition. Let someone else do the cooking or use prepared food from the freezer.

Habit Forming

No

Author Details

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Disease/Condition Glossary

Nausea and vomiting: Nausea is a feeling of uneasiness of the stomach that often comes before vomiting. On the other hand, vomiting is the forcible voluntary or involuntary emptying of stomach contents through the mouth. In short, nausea and vomiting are not diseases but are symptoms of many conditions like infections, motion sickness, an early stage of pregnancy, and gastroparesis (slow stomach emptying). A receptor located in the brain known as the chemoreceptor trigger zone (CTZ) controls vomiting.

Ondem Injection 10 x 2 ml Substitute

Substitutes safety advice
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