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Written By aquibnaseer ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Composition :

DEFLAZACORT-6MG

Manufacturer/Marketer :

SEIKOMAX HEALTHCARE

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Ostodef-6 Tablet

Ostodef-6 Tablet belongs to the class of medication called steroid primarily used to treat Duchene muscular dystrophy in adults and children above 2 years of age. Autoimmune disease is a health disorder in which the immune system doesn't work normally & is unable to distinguish between a foreign cell & a native cell. This condition results in an immune system that starts to attack native cells & organs, leading to medical problems like Duchenne muscular dystrophy, psoriasis & arthritis, etc.

Ostodef-6 Tablet is an immunosuppressive drug that works by binding to immune system cells and turns off the switches (receptors) that lead to their abnormal functioning or damaging effects. After taking the drug Ostodef-6 Tablet binds to immune cells, resulting in the inhibition of inflammation & autoimmune diseases that occur due to the production of chemicals called cytokines responsible for inflammation. Thus, a Ostodef-6 Tablet class of drugs is beneficial in autoimmune diseases and inflammation that causes harm in various organs, especially in joints in arthritis & skin psoriasis. Ostodef-6 Tablet make organ transplantation possible & treats muscle disorders like Duchenne muscular dystrophy.

Ostodef-6 Tablet is available in both oral tablet and suspension dosage forms. The tablet form of Ostodef-6 Tablet can be taken with or without food and swallowed whole with a water glass. Do not crush, chew or break it. The liquid form of Ostodef-6 Tablet can be taken as advised by your doctor with a measuring cup. Your doctor will recommend how often you take Ostodef-6 Tablet based on your medical condition. Some people may experience nausea, chest pain, vomiting, drowsiness, headache, dizziness, skin rash, tremor, nervousness, diarrhoea and fast heartbeats. Most of these side effects of Ostodef-6 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. Do not quit taking deflazacort without consulting your physician. Symptoms such as loss of appetite, a disturbed stomach, vomiting, drowsiness, confusion, headache, fever, joint and muscle pain, peeling skin, and weight loss may be caused by stopping the medication suddenly.

Before starting Ostodef-6 Tablet , please inform your doctor that you are allergic (hypersensitive) to Ostodef-6 Tablet . Extra care is to be taken when a patient has an already existing infection being treated (systemic infection) or has recently had some live virus vaccines. Doctors' consultation is required as Ostodef-6 Tablet is not safe to use during pregnancy. 

Uses of Ostodef-6 Tablet

Duchenne muscular dystrophy (DMD) 

Directions for Use

Tablet: Swallow this tablet whole with a glass of water at the start of a meal or slightly before. Space the doses evenly during the course. Do not chew or crush it. If you cannot swallow the tablet as a whole, you may break the pill into half and take both halves one at a time.Suspension: Measure the suspension in the measuring cup provided with the pack and consume it in the doses as directed by your doctor.

Medicinal Benefits

Ostodef-6 Tablet is beneficial in inflammatory diseases, including asthma, arthritis, and allergies. It is used in the treatment of Duchenne muscular dystrophy (DMD). It raises the amount of glucocorticoid in the body. It works by reducing the formation of inflammatory substances and suppressing immunity to prevent self-damage caused by the immune system (auto-immune reactions occurring in organ transplants, autoimmune diseases, or cancer). Ostodef-6 Tablet is a steroid that interacts with overactive immune cells and slows their activity and decreases the damaging effects they cause in the body. 

Storage

Store in a cool and dry place away from sunlight
Side effects of Ostodef-6 Tablet
  • Eat a balanced diet with proteins, whole grains, fruits, and vegetables; avoid processed foods and excess sugar.
  • Practice physical activity for at least 30 minutes, such as cardio or strength training.
  • Consider intermittent fasting to help with fat reduction.
  • Maintain at least seven hours of sleep to prevent weight gain.
  • Manage stress with yoga, meditation, or deep breathing.
  • Limit alcohol and sugary drinks to reduce fat accumulation.
  • Stay hydrated by drinking plenty of water.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Drink six to eight glasses of water per day to be healthy.
  • Healthy urinary habits can help minimize pollakiuria (frequent urinating).
  • Avoid liquids containing caffeine, artificial sweeteners, and soda, as they might cause bladder discomfort.
  • Add bladder-friendly foods such as omega-3 fatty acids, blueberries, and cranberries.
  • Regular cleansing will help get rid of dead skin cells and stop ingrown hairs.
  • Keep your hormones in balance by managing your stress, eating well and exercising regularly.
  • Shaving, waxing, and bleaching are ways to get rid of extra hair.
  • Eat fiber-rich foods, fruits, and vegetables, and track your food intake to monitor calorie consumption.
  • Limit takeout and restaurant meals, and weigh yourself weekly to stay motivated.
  • Build balanced meals, allow yourself to enjoy treats in moderation, and prioritize sleep and stress management through exercise and relaxation techniques.
Managing Medication-Triggered Erythema (Redness of the Skin or Skin redness): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.

Drug Warnings

Patients with a history of tuberculosis (TB), heart disease or heart failure stomach disorders (gastritis, peptic ulcer), diabetes (including family history), osteoporosis (bone disease), myasthenia gravis (muscle weakness), depression, mental distress, history of muscular problems caused by corticosteroids, kidney & liver dysfunction (including hepatic insufficiency and cirrhosis), should consult a doctor before using Ostodef-6 Tablet .  This medicine is not recommended for children less than 5 years of age, lactating mothers and pregnant women. Avoid going near people who are sick or infected while using Ostodef-6 Tablet . Before taking Ostodef-6 Tablet for at least, 4-6 weeks do not take any live vaccine as it may cause severe allergic reactions. 

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Ostodef-6 Tablet:
Co-administration of Ostodef-6 Tablet and Desmopressin may increase the risk of hyponatremia (low levels of salt in the blood).

How to manage the interaction:
Although co- administration of Daflazacort with Desmopression can possibly lead to an interaction, it can be taken in case a doctor advices you. You should seek medical attention if you experience loss of appetite, nausea, vomiting, headache, lethargy, irritability, difficulty in concentrating, memory impairment, confusion, muscle spasm, weakness, unsteadiness, decreased urination, or sudden weight gain. Do not stop using any medications without consulting a doctor.
How does the drug interact with Ostodef-6 Tablet:
Sparfloxacin can cause tendinitis (inflammation of the thick fibrous cords that attach muscle to bone) and tendon rupture (injury to the soft tissue that connect muscle to bone), and the risk may be increased when combined with other drugs such as Ostodef-6 Tablet.

How to manage the interaction:
Although there is an interaction, Sparfloxacin can be taken with Ostodef-6 Tablet if prescribed by the doctor. However, if you experience pain, swelling at the back of the ankle, biceps, shoulder, hand, or thumb, consult a doctor immediately. Avoid exercise or use of the affected area until further instruction from your doctor. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Ostodef-6 Tablet:
Norfloxacin can cause tendinitis (inflammation of the thick fibrous cords that attach muscle to bone) and tendon rupture (injury to the soft tissue that connect muscle to bone), and the risk may be increased when combined with other drugs such as Ostodef-6 Tablet.

How to manage the interaction:
Although there is an interaction, Norfloxacin can be taken with Ostodef-6 Tablet if prescribed by the doctor. However, if you experience pain, or swelling at the back of the ankle, biceps, shoulder, hand, or thumb, consult a doctor immediately. Avoid exercise or use of the affected area until further instruction from your doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Ostodef-6 Tablet:
Gatifloxacin can cause tendinitis (inflammation of the thick fibrous cords that attach muscle to bone) and tendon rupture (injury to the soft tissue that connect muscle to bone), and the risk may be increased when combined with other drugs such as Ostodef-6 Tablet.

How to manage the interaction:
Although there is an interaction, Gatifloxacin can be taken with Ostodef-6 Tablet if prescribed by the doctor. However, if you experience pain, swelling at the back of the ankle, biceps, shoulder, hand, or thumb, consult a doctor immediately. Avoid exercise or use of the affected area until further instruction from your doctor. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Ostodef-6 Tablet:
Co-administration Bempedoic acid and Ostodef-6 Tablet can result in tendinitis (inflammation of the thick fibrous cords that connect muscle to bone) and tendon rupture.

How to manage the interaction:
Although taking Bempedoic acid and Ostodef-6 Tablet together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have pain, swelling, or inflammation in a muscle location such as the back of the ankle, shoulder, or biceps. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Ostodef-6 Tablet:
Taking Bosentan with Ostodef-6 Tablet may significantly reduce the blood levels of Ostodef-6 Tablet, which may make the medication less effective in treating the condition.

How to manage the interaction:
Although using Bosentan and Ostodef-6 Tablet together can result in an interaction, they can be taken together if advised by your doctor. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Ostodef-6 Tablet:
Co-administration of Ostodef-6 Tablet with Cladribine may increase the risk of infections.

How to manage the interaction:
Although there is a possible interaction between Ostodef-6 Tablet and Cladribine, you can take these medicines together if prescribed by your doctor. If you have any of the symptoms like fever, chills, diarrhea, sore throat, muscle pain, weight loss, and pain or burning when you urinate, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Ostodef-6 Tablet:
Taking Modafinil with Ostodef-6 Tablet may significantly reduce the blood levels of Ostodef-6 Tablet, which may make the medication less effective in treating the condition.

How to manage the interaction:
Although using Modafinil and Ostodef-6 Tablet together can possibly result in an interaction, they can be taken together if advised by your doctor. However, consult your doctor if your condition worsens. Do not stop taking any medications without consulting a doctor.
How does the drug interact with Ostodef-6 Tablet:
Coadministration of Diltiazem with Ostodef-6 Tablet can increase the levels of Ostodef-6 Tablet in the body. This increases the risk of side effects.

How to manage the interaction:
Taking Diltiazem with Ostodef-6 Tablet together can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, shortness of breath, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Ostodef-6 Tablet:
Taking Dexamethasone with Ostodef-6 Tablet may significantly reduce the blood levels of Ostodef-6 Tablet, which may make the medication less effective in treating the condition.

How to manage the interaction:
Although using Dexamethasone and Ostodef-6 Tablet together can possibly result in an interaction, they can be taken together if advised by your doctor. Do not stop taking any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

A patient needs to take extra care of hygiene & stay away from places/people believed to be a cause of infection as this drug affects a patient's immune system & thus proper care is to be taken.

 

Habit Forming

No

Therapeutic Class

ANTI- INFLAMMATORY AGENTS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Not recommended in mild allergies. Ostodef-6 Tablet is recommended only on consulting a doctor as Ostodef-6 Tablet is a strong medicine that produces considerable side effects & thus used only in moderate to severe cases.

It is not recommended to stop by a patient himself/herself, especially by a patient undergoing organ transplantation as it may worsen the situation.

It is not recommended to be taken Ostodef-6 Tablet with alcohol as it may cause stomach bleeding.

No its is not recommended to be used in seasonal allergy or mild cases. Only on doctors consultation, Ostodef-6 Tablet may be used in extreme cases of seasonal allergy.

You should not use Ostodef-6 Tablet if you have taken live vaccines of mumps, measles, rubella (MMR), polio, rotavirus, yellow fever, typhoid, nasal flu (influenza), varicella (chickenpox), and zoster (shingles). Do not take Ostodef-6 Tablet if you have a compromised immune system, eye problems or weak bones.

Drug-Drug Interactions Checker List

  • RIFAMPICIN
  • RIFABUTIN
  • CARBAMAZEPINE
  • PHENOBARBITONE
  • PHENYTOIN
  • PRIMIDONE

Special Advise

  • While taking Ostodef-6 Tablet and for at least 4-6 weeks before you start taking it. If you are taking Ostodef-6 Tablet , so do not receive a 'live' vaccine or you could develop a serious infection.  
  • Do not eat grapefruit or drink grapefruit juice while taking this medication as grapefruit has interaction with Ostodef-6 Tablet .
  • Regular eye check-ups, bone mineral test and liver function test is suggested while using Ostodef-6 Tablet . 

Disease/Condition Glossary

Autoimmune disease: These are a group of disorders in which the immune system doesn't work properly due to various genetic & environmental reasons that starts attacking normal cells, producing various chemicals resulting in unwanted and hazardous effects in patients. The overactive immune system leads to various symptoms that affect day to day life and promote diseases like arthritis, muscular weakness. The immune system can also damage the organ, which has been transplanted to the patient from another person due to having different blood groups/antigens of donor patients organ. The immune system considers it a foreign harmful body, leading to complications after transplanting an organ like a kidney, liver, or heart. 

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