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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

Online payment accepted

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Whats That

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Composition :

OXALIPLATIN-100MG

Manufacturer/Marketer :

Samarth Life Sciences Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Oxoplan 100 Injection

Oxoplan 100 Injection belongs to the group of medicines called platinum-containing antineoplastic agents used alone or in combination with other anti-cancer medicines to treat cancer of the large bowel/intestine (advanced colon or colorectal cancer). 
 
Oxoplan 100 Injection contains Oxaliplatin, which works by killing the cancer cells. Thereby, it helps treat cancer.
 
In some cases, Oxoplan 100 Injection may cause side effects such as mild nausea, vomiting, diarrhoea, fever, and headache. Most of these side effects may not require medical attention and resolve gradually over time. Do not be reluctant to talk with your doctor if any of the side effects persist or worsen.
 
Do not use Oxoplan 100 Injection if you are breastfeeding. Consult a doctor immediately if you become pregnant during treatment with Oxoplan 100 Injection. This medicine is not recommended for children as safety and effectiveness have not been established. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Uses of Oxoplan 100 Injection

Colon and rectal cancer

Directions for Use

Oxoplan 100 Injection will be administered by a qualified physician; do not self-administer.

Medicinal Benefits

Oxoplan 100 Injection contains Oxaliplatin, which belongs to the group of medicines called platinum-containing antineoplastic agents used to treat stage III colon cancer after complete removal of the primary tumour and metastatic cancer of the colon and rectum. It is used in combination with other anti-cancer medicines, such as 5-fluorouracil and folinic acid. Oxoplan 100 Injection works by killing the cancer cells. Thereby, it helps treat cancer. Oxoplan 100 Injection may also be used with other medicines to prevent colon cancer from spreading in patients who have had surgery to remove the tumour.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Oxoplan 100 Injection

  • Mild nausea
  • Vomiting
  • Diarrhoea
  • Headache
  • Peripheral neuropathy
  • Fatigue
  • Back pain
  • Stomach pain

Drug Warnings

Do not use Oxoplan 100 Injection if you are allergic to any of its components, if you are breastfeeding, have a low blood cell count, have severe kidney problems, tingling and numbness in the fingers/toes, and have difficulty performing fragile tasks, such as buttoning clothes. Inform the doctor if you ever suffered an allergic reaction to platinum-containing medicines, have mild/moderate kidney problems, liver problems or abnormal liver function tests during therapy, or heart disorders like prolongation of the QT interval (abnormal electrical signal), an irregular heartbeat, or a family history of heart problems. Seek immediate medical attention if you experience symptoms of an allergic reaction (rash, itching, hives, reddening of the skin, hoarseness, difficulty breathing or swallowing, feeling as if your throat is closing, dizziness, swelling of the lips and tongue, lightheadedness, or fainting), unpleasant sensation in the throat, rhabdomyolysis (muscle pain and swelling), nerve problems (sensitivity to cold temperature or cold objects, pain, tingling or burning sensation), Posterior Reversible Encephalopathy Syndrome (headache, confusion, seizures, vision problems), myelosuppression (chills or shivering, burning or pain on urination, pain on swallowing, sore throat, cough with mucus, persistent diarrhoea), lung problems (shortness of breath, wheezing, cough), or bleeding problems (vomit that looks like coffee grounds or bloody vomit, pink or brown urine, weakness, dizziness, changes in speech, confusion, unexplained bleeding or dark-coloured/tarry stools).

Drug-Drug Interactions

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OxaliplatinZiprasidone
Critical
OxaliplatinHydroxychloroquine
Severe

Drug-Drug Interactions

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OxaliplatinZiprasidone
Critical
How does the drug interact with Oxoplan 100 Injection:
Combining Oxoplan 100 Injection with Ziprasidone can increase the risk of QTc prolongation.

How to manage the interaction:
Taking Oxoplan 100 Injection with Ziprasidone is not recommended, please consult your doctor before taking it.
OxaliplatinHydroxychloroquine
Severe
How does the drug interact with Oxoplan 100 Injection:
The combined use of Oxoplan 100 Injection and Hydroxychloroquine can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of oxalipatin and Hydroxychloroquine can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
OxaliplatinCeritinib
Severe
How does the drug interact with Oxoplan 100 Injection:
Taking Oxoplan 100 Injection with ceritinib can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although there is a interaction between Oxoplan 100 Injection and Ceritinib, but it can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
OxaliplatinIvabradine
Severe
How does the drug interact with Oxoplan 100 Injection:
Using ivabradine together with Oxoplan 100 Injection can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is a possible interaction between Oxoplan 100 Injection and Ivabradine, you can take these medicines together if prescribed by your doctor. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
OxaliplatinHaloperidol
Severe
How does the drug interact with Oxoplan 100 Injection:
Co-administration of Oxoplan 100 Injection and Haloperidol can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Co-administration of Oxoplan 100 Injection and Haloperidol can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
OxaliplatinEtanercept
Severe
How does the drug interact with Oxoplan 100 Injection:
When Etanercept is used with Oxoplan 100 Injection, the likelihood or severity of infection may increase.

How to manage the interaction:
Although there is a possible interaction between Oxoplan 100 Injection and Etanercept, you can take these medicines together if prescribed by a doctor. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
OxaliplatinMifepristone
Severe
How does the drug interact with Oxoplan 100 Injection:
Co-administration of Oxoplan 100 Injection with mifepristone can increase the risk of irregular heart rhythms.

How to manage the interaction:
Taking Oxoplan 100 Injection with mifepristone together is avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not discontinue any medications without consulting a doctor.
OxaliplatinAmisulpride
Severe
How does the drug interact with Oxoplan 100 Injection:
Using amisulpride together with Oxoplan 100 Injection can increase the risk of severe irregular heart rhythm.

How to manage the interaction:
Co-administration of Oxoplan 100 Injection with Amisulpride can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without a doctor's advice.
OxaliplatinGatifloxacin
Severe
How does the drug interact with Oxoplan 100 Injection:
Taking Oxoplan 100 Injection with Gatifloxacin can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Oxoplan 100 Injection with Gatifloxacin together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OxaliplatinChloroquine
Severe
How does the drug interact with Oxoplan 100 Injection:
Using chloroquine together with Oxoplan 100 Injection can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking chloroquine and Oxoplan 100 Injection together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include vegetables and fruits in your diet.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.
  • Get optimal sleep; rest well.
  • Drink enough water and eat fibre-rich foods, vegetables and fruits.

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY

Oxoplan 100 Injection Substitute

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Oxoplan 100 Injection works by killing the cancer cells. Thereby, it helps treat cancer.

Oxoplan 100 Injection may have an anti-fertility effect, which could be irreversible. Therefore, male patients should seek medical advice on the conservation of sperm prior to treatment with Oxoplan 100 Injection.

Avoid drinking or eating anything colder than room temperature. Do not touch any cold objects, wash your hands in cold water, go near air conditioners or freezers, or go outside in cold weather unless absolutely necessary for five days after you receive each dose of Oxoplan 100 Injection. Wear a hat, gloves, and a scarf, and cover your mouth and nose if you must go outside in cold weather.

Oxoplan 100 Injection may decrease the ability to fight infections due to reduced white blood cells. Stay away from sick people during treatment with Oxoplan 100 Injection.

Special Advise

  • Women must use reliable contraception during treatment and for nine months after receiving the last dose.
  • Male patients are advised not to father a child during treatment and for six months after the last dose. Use effective contraception during this time.
  • If you are due to undergo any surgery, including dental surgery, inform the doctor/dentist that you are on treatment with Oxoplan 100 Injection.
  • Avoid eating or drinking anything that is colder than room temperature for five days after receiving each dose of Oxoplan 100 Injection. To reduce side effects caused by cold temperature-cover yourself with a blanket while getting treatment with Oxoplan 100 Injection, wear warm clothing in cold weather at all times, cover your mouth and nose with a scarf and wear gloves whilst touching cold objects. Drink fluid at room/warm temperature and always drink through a straw. Avoid using ice and AC, touching cold metals, and breathing deeply when exposed to cold air.

Disease/Condition Glossary

Colon and rectal cancer: It is a cancer of the colon or rectum. Colorectal cancer is the growth of cells that form in the lower end of the digestive tract. Most of these cancers begin as polyps (non-cancerous growths). Symptoms may include abdominal discomfort, blood in the stool, and changes in bowel habits like constipation or diarrhoea.

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