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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
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Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About Oxyrea 100 Injection 1's

Oxyrea 100 Injection 1's belongs to the group of medicines called platinum-containing antineoplastic agents used alone or in combination with other anti-cancer medicines to treat cancer of the large bowel/intestine (advanced colon or colorectal cancer). 
 
Oxyrea 100 Injection 1's contains Oxaliplatin, which works by killing the cancer cells. Thereby, it helps treat cancer.
 
In some cases, Oxyrea 100 Injection 1's may cause side effects such as mild nausea, vomiting, diarrhoea, fever, and headache. Most of these side effects may not require medical attention and resolve gradually over time. Do not be reluctant to talk with your doctor if any of the side effects persist or worsen.
 
Do not use Oxyrea 100 Injection 1's if you are breastfeeding. Consult a doctor immediately if you become pregnant during treatment with Oxyrea 100 Injection 1's. This medicine is not recommended for children as safety and effectiveness have not been established. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Uses of Oxyrea 100 Injection 1's

Colon and rectal cancer

Directions for Use

Oxyrea 100 Injection 1's will be administered by a qualified physician; do not self-administer.

Medicinal Benefits

Oxyrea 100 Injection 1's contains Oxaliplatin, which belongs to the group of medicines called platinum-containing antineoplastic agents used to treat stage III colon cancer after complete removal of the primary tumour and metastatic cancer of the colon and rectum. It is used in combination with other anti-cancer medicines, such as 5-fluorouracil and folinic acid. Oxyrea 100 Injection 1's works by killing the cancer cells. Thereby, it helps treat cancer. Oxyrea 100 Injection 1's may also be used with other medicines to prevent colon cancer from spreading in patients who have had surgery to remove the tumour.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Oxyrea 100 Injection 1's

  • Mild nausea
  • Vomiting
  • Diarrhoea
  • Headache
  • Peripheral neuropathy
  • Fatigue
  • Back pain
  • Stomach pain

Drug Warnings

Do not use Oxyrea 100 Injection 1's if you are allergic to any of its components, if you are breastfeeding, have a low blood cell count, have severe kidney problems, tingling and numbness in the fingers/toes, and have difficulty performing fragile tasks, such as buttoning clothes. Inform the doctor if you ever suffered an allergic reaction to platinum-containing medicines, have mild/moderate kidney problems, liver problems or abnormal liver function tests during therapy, or heart disorders like prolongation of the QT interval (abnormal electrical signal), an irregular heartbeat, or a family history of heart problems. Seek immediate medical attention if you experience symptoms of an allergic reaction (rash, itching, hives, reddening of the skin, hoarseness, difficulty breathing or swallowing, feeling as if your throat is closing, dizziness, swelling of the lips and tongue, lightheadedness, or fainting), unpleasant sensation in the throat, rhabdomyolysis (muscle pain and swelling), nerve problems (sensitivity to cold temperature or cold objects, pain, tingling or burning sensation), Posterior Reversible Encephalopathy Syndrome (headache, confusion, seizures, vision problems), myelosuppression (chills or shivering, burning or pain on urination, pain on swallowing, sore throat, cough with mucus, persistent diarrhoea), lung problems (shortness of breath, wheezing, cough), or bleeding problems (vomit that looks like coffee grounds or bloody vomit, pink or brown urine, weakness, dizziness, changes in speech, confusion, unexplained bleeding or dark-coloured/tarry stools).

Drug-Drug Interactions

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OxaliplatinZiprasidone
Critical
OxaliplatinCladribine
Severe

Drug-Drug Interactions

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OxaliplatinZiprasidone
Critical
How does the drug interact with Oxyrea 100 Injection:
Combining Oxyrea 100 Injection with Ziprasidone can increase the risk of QTc prolongation.

How to manage the interaction:
Taking Oxyrea 100 Injection with Ziprasidone is not recommended, please consult your doctor before taking it.
OxaliplatinCladribine
Severe
How does the drug interact with Oxyrea 100 Injection:
Combining Cladribine with Oxyrea 100 Injection can increase the risk of developing serious infections.

How to manage the interaction:
Although there is a possible interaction between Oxyrea 100 Injection and Cladribine, you can take these medicines together if prescribed by your doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
OxaliplatinBaricitinib
Severe
How does the drug interact with Oxyrea 100 Injection:
Coadministration of baricitinib and Oxyrea 100 Injection can raise the risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, baricitinib can be taken with Oxyrea 100 Injection if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without talking to a doctor.
OxaliplatinIvabradine
Severe
How does the drug interact with Oxyrea 100 Injection:
Using ivabradine together with Oxyrea 100 Injection can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is a possible interaction between Oxyrea 100 Injection and Ivabradine, you can take these medicines together if prescribed by your doctor. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
OxaliplatinThalidomide
Severe
How does the drug interact with Oxyrea 100 Injection:
Taking thalidomide together with Oxyrea 100 Injection may increase the risk of blood clots and other complications.

How to manage the interaction:
Although taking thalidomide and Oxyrea 100 Injection together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
OxaliplatinGatifloxacin
Severe
How does the drug interact with Oxyrea 100 Injection:
Taking Oxyrea 100 Injection with Gatifloxacin can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Oxyrea 100 Injection with Gatifloxacin together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OxaliplatinAmiodarone
Severe
How does the drug interact with Oxyrea 100 Injection:
Coadministration of Amiodarone together with Oxyrea 100 Injection may raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Even though Amiodarone and Oxyrea 100 Injection interact, they can be used if prescribed by a doctor. If you have cardiac problems or electrolyte imbalances, you may be at greater risk. If you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, get medical attention. Do not discontinue any medications without consulting a doctor.
OxaliplatinTofacitinib
Severe
How does the drug interact with Oxyrea 100 Injection:
Taking Tofacitinib with Oxyrea 100 Injection may increase the risk of infection.

How to manage the interaction:
Although taking Oxyrea 100 Injection and Tofacitinib together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without talking to your doctor.
OxaliplatinSotalol
Severe
How does the drug interact with Oxyrea 100 Injection:
Using sotalol together with Oxyrea 100 Injection can increase the risk of an irregular heart rhythm. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Although there is a possible interaction between Sotalol and Oxyrea 100 Injection, you can take these medicines together if prescribed by a doctor. If you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations consult a doctor. Do not stop using any medications without talking to a doctor.
OxaliplatinEfavirenz
Severe
How does the drug interact with Oxyrea 100 Injection:
Taking Oxyrea 100 Injection with Efavirenz can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Oxyrea 100 Injection with Efavirenz together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include vegetables and fruits in your diet.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.
  • Get optimal sleep; rest well.
  • Drink enough water and eat fibre-rich foods, vegetables and fruits.

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY

Oxyrea 100 Injection 1's Substitute

Substitutes safety advice
  • OXITAN 100MG INJECTION 50ML

    by Others

    85.75per tablet
  • DACOTIN 100MG INJECTION

    by Others

    4287.40per tablet
  • Dacotin Rtu-100 Injection 20 ml

    by Others

    214.37per tablet
  • Soxplat 100 mg Injection 1's

    by Others

    4059.00per tablet
  • Oxoplan 100 Injection 1's

    by Others

    3765.52per tablet

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Special Advise

  • Women must use reliable contraception during treatment and for nine months after receiving the last dose.
  • Male patients are advised not to father a child during treatment and for six months after the last dose. Use effective contraception during this time.
  • If you are due to undergo any surgery, including dental surgery, inform the doctor/dentist that you are on treatment with Oxyrea 100 Injection 1's.
  • Avoid eating or drinking anything that is colder than room temperature for five days after receiving each dose of Oxyrea 100 Injection 1's. To reduce side effects caused by cold temperature-cover yourself with a blanket while getting treatment with Oxyrea 100 Injection 1's, wear warm clothing in cold weather at all times, cover your mouth and nose with a scarf and wear gloves whilst touching cold objects. Drink fluid at room/warm temperature and always drink through a straw. Avoid using ice and AC, touching cold metals, and breathing deeply when exposed to cold air.

Disease/Condition Glossary

Colon and rectal cancer: It is a cancer of the colon or rectum. Colorectal cancer is the growth of cells that form in the lower end of the digestive tract. Most of these cancers begin as polyps (non-cancerous growths). Symptoms may include abdominal discomfort, blood in the stool, and changes in bowel habits like constipation or diarrhoea.

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