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  3. Pregaba D 75/20 Capsule 10's

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Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
COD available

Online payment accepted

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Manufacturer/Marketer :

Torrent Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Pregaba D 75/20 Capsule

Pregaba D 75/20 Capsule belongs to an anticonvulsant class of medicines. It is used in the treatment of diabetic neuropathic pain and fibromyalgia. Neuropathic pain/ peripheral neuropathy is pain that occurs when the nervous system is not working properly or is damaged. Diabetic neuropathic pain/diabetic neuropathy is a condition causing moderate to severe pain due to damage of nerves in the thigh, hip, buttock and leg regions. Symptoms may include tingling, shooting pain, burning, or even an electric shock sensation. Fibromyalgia is a chronic condition with moderate pain and tenderness all over the body resulting in fatigue and trouble sleeping.

Pregaba D 75/20 Capsule is a combination of Pregabalin and Duloxetine. Pregabalin belongs to an anticonvulsant class of drugs, whereas Duloxetine is a selective serotonin reuptake (SSRI) inhibitor. This medicine mainly works by increasing the chemical messengers in the brain responsible for regulating pain.

Pregaba D 75/20 Capsule can be taken with or without food or as prescribed by your doctor. Pregaba D 75/20 Capsule may cause certain side effects such as nausea, constipation, headache, dry mouth, increased sweating, loss of appetite, dizziness, and burning sensation. These side effects do not require medical attention and gradually resolve over time. However, if any of these side effects persist, inform your doctor.

Pregaba D 75/20 Capsule should be avoided if you are allergic to it. Inform your doctor if you have any liver or kidney disease, seizures (fits), mania, bipolar disorder, glaucoma (an eye condition), bleeding disorders, or are at risk of hyponatremia (low sodium levels, especially in patients taking diuretics or water pills). If you are pregnant or breastfeeding, inform your doctor before taking this medicine. It is not recommended for use in children and young adults as it increases the risk of suicidal tendencies. 

Uses of Pregaba D 75/20 Capsule

Diabetic Neuropathic Pain, Fibromyalgia

Directions for Use

Take Pregaba D 75/20 Capsule as prescribed by your doctor. Swallow it as a whole with water. It can be taken with or without food. Do not crush, break or chew it.

Medicinal Benefits

Pregaba D 75/20 Capsule contains Pregabalin and Duloxetine. Pregabalin belongs to an anticonvulsant class of drugs, whereas Duloxetine is a selective serotonin reuptake (SSRI) inhibitor. This medicine mainly works by increasing the chemical messengers in the brain responsible for regulating pain. Pregaba D 75/20 Capsule effectively treats neuropathic pain, and improves nerve conduction for proper nerve signal functioning in the body. 

Storage

Keep Pregaba D 75/20 Capsule out of the sight and reach of children.

Drug Warnings

Pregaba D 75/20 Capsule should be avoided if you are allergic to any of the components in it. Do not stop taking Pregaba D 75/20 Capsule suddenly without your doctor’s advice, as it may cause withdrawal symptoms like dizziness, tingling sensation, sleep disturbances, restlessness, nausea or vomiting, headache, or excessive sweating. Inform your doctor if you have any liver or kidney disease, seizures (fits), mania, bipolar disorder, or glaucoma (an eye condition). Pregaba D 75/20 Capsule may increase suicidal thoughts, so it is advised to use caution in patients with mania, bipolar disorder or depression. It is not recommended for use in children below 18 years of age as the safety and efficacy of this medicine are not established. Pregnant or breastfeeding mothers should inform the doctor before using Pregaba D 75/20 Capsule .

Drug-Drug Interactions

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NortriptylinePotassium citrate
Critical

Drug-Drug Interactions

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How does the drug interact with Pregaba D 75/20 Capsule:
Coadministration of Pregaba D 75/20 Capsule with Safinamide may increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Pregaba D 75/20 Capsule with Safinamide together can result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting your doctor.
NortriptylinePotassium citrate
Critical
How does the drug interact with Pregaba D 75/20 Capsule:
Coadministration of Pregaba D 75/20 Capsule with Potassium citrate can increase the risk or severity of gastric bleeding, ulceration, and rarely, perforation leading to serious blood loss.

How to manage the interaction:
Taking Pregaba D 75/20 Capsule with Potassium citrate together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, dizziness, lightheadedness, abdominal pain, bloating, decreased hunger, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Pregaba D 75/20 Capsule:
Coadministration of Pregaba D 75/20 Capsule with Tranylcypromine can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Pregaba D 75/20 Capsule with Tranylcypromine together can result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
NortriptylineIsocarboxazid
Critical
How does the drug interact with Pregaba D 75/20 Capsule:
Using Pregaba D 75/20 Capsule together with Isocarboxazid can increase the risk of serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is especially a mood stabilizer).

How to manage the interaction:
Taking Isocarboxazid with Pregaba D 75/20 Capsule is not recommended, please consult your doctor before taking it. However, if you experience increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasms or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea call a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Pregaba D 75/20 Capsule:
Co-administration of Pregaba D 75/20 Capsule with Selegiline might raise serotonin hormone levels in the body (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Taking Pregaba D 75/20 Capsule with Selegiline together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience confusion, hallucination, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Pregaba D 75/20 Capsule:
Coadministration of Pregaba D 75/20 Capsule with Ziprasidone can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Pregaba D 75/20 Capsule with Ziprasidone together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, severe or prolonged diarrhea, or vomiting. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Pregaba D 75/20 Capsule:
Coadministration of Pregaba D 75/20 Capsule with Linezolid might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to side effects.

How to manage the interaction:
Taking Pregaba D 75/20 Capsule with Linezolid together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Pregaba D 75/20 Capsule:
Coadministration of Pregaba D 75/20 Capsule with Haloperidol can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Pregaba D 75/20 Capsule with Haloperidol together can result in an interaction, but it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, dry mouth, visual disturbances, urinary retention, or constipation. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Pregaba D 75/20 Capsule:
Co-administration of Pregaba D 75/20 Capsule with Fluoxetine can reduce the metabolism and increase the levels of Pregaba D 75/20 Capsule in the body. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Pregaba D 75/20 Capsule with Fluoxetine together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of headaches, dry mouth, sleepiness, irritation, confusion, edema, fatigue, palpitations, or constipation, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
NortriptylineMetaraminol
Severe
How does the drug interact with Pregaba D 75/20 Capsule:
Coadministration of Pregaba D 75/20 Capsule with Metaraminol can increase blood pressure.

How to manage the interaction:
Although taking Metaraminol and Pregaba D 75/20 Capsule together can cause an interaction, it can be taken if your doctor has suggested it. It's important to keep an eye on your blood pressure regularly. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Exercise regularly, which helps in reducing pain.
  • Rest well, and get enough sleep.
  • Always take a warm bath, as it can be soothing.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity, and improves coping skills.

Side Effects of Pregaba D 75/20 Capsule

  • Burning sensation
  • Drowsiness
  • Nausea
  • Constipation
  • Headache
  • Dry mouth
  • Increased sweating
  • Loss of appetite

Habit Forming

Yes

Therapeutic Class

ANTICONVULSANT

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Pregaba D 75/20 Capsule contains Pregabalin and Duloxetine. Pregabalin belongs to an anticonvulsant class of drugs, whereas Duloxetine is a selective serotonin reuptake (SSRI) inhibitor. This medicine mainly works by increasing the chemical messengers in the brain responsible for regulating pain.

Do not stop using Pregaba D 75/20 Capsule suddenly as it can cause withdrawal symptoms. Your doctor will gradually reduce the dose based on your clinical condition.

Seek medical attention immediately if you notice any depressive thoughts while using Pregaba D 75/20 Capsule . Your doctor may change the dose or medicine to treat your condition.

Neuropathic pain/ peripheral neuropathy is pain that occurs when the nervous system is not working properly or is damaged.

Drug-Drug Interactions Checker List

  • TRAMADOL
  • FLUOXETINE
  • MOCLOBEMIDE
  • VENLAFAXINE
  • AMITRIPTYLINE

Special Advise

  • Do not stop taking Pregaba D 75/20 Capsule suddenly, as it may cause withdrawal symptoms.
  • Do frequent blood tests to check your fasting blood glucose, HbA1c, and total cholesterol (TC) levels to reduce any serious side effects.

Disease/Condition Glossary

Diabetic Neuropathy: Diabetic neuropathic pain/diabetic neuropathy is a condition causing moderate to severe pain due to damage of nerves in the thigh, hip, buttock and leg regions. Symptoms may include tingling, shooting pain, burning, or even an electric shock sensation. It mainly occurs in patients suffering from Type II Diabetes.

Fibromyalgia: It is a chronic condition with moderate pain and tenderness of the muscle all over the body. It mainly occurs due to physical or psychological stress. Symptoms may include fatigue, tiredness, trouble sleeping, anxiety, headache and depression.

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Alcohol

Unsafe

Avoid alcohol consumption during treatment with $nmae as it may increase the risk of serious side effects and worsen your health.

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Pregnancy

Caution

If you are pregnant, especially in the last trimester or planning pregnancy, inform your doctor before taking Pregaba D 75/20 Capsule . It may cause foetal abnormalities if taken in the last trimester of pregnancy. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Caution

If you are breastfeeding, inform your doctor before taking Pregaba D 75/20 Capsule . Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Unsafe

Pregaba D 75/20 Capsule may cause drowsiness. Hence, avoid driving vehicles or operating machines after taking Pregaba D 75/20 Capsule .

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Liver

Caution

If you have liver conditions, inform your doctor before taking Pregaba D 75/20 Capsule . Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

If you have kidney conditions, inform your doctor before taking Pregaba D 75/20 Capsule . Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Pregaba D 75/20 Capsule is not recommended for children below 18 years as the safety and efficacy of use for this medicine are not established. Please seek medical advice for more information.

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