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Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

About Pregaba D 75/20 Capsule 10's

Pregaba D 75/20 Capsule 10's belongs to an anticonvulsant class of medicines. It is used in the treatment of diabetic neuropathic pain and fibromyalgia. Neuropathic pain/ peripheral neuropathy is pain that occurs when the nervous system is not working properly or is damaged. Diabetic neuropathic pain/diabetic neuropathy is a condition causing moderate to severe pain due to damage of nerves in the thigh, hip, buttock and leg regions. Symptoms may include tingling, shooting pain, burning, or even an electric shock sensation. Fibromyalgia is a chronic condition with moderate pain and tenderness all over the body resulting in fatigue and trouble sleeping.

Pregaba D 75/20 Capsule 10's is a combination of Pregabalin and Duloxetine. Pregabalin belongs to an anticonvulsant class of drugs, whereas Duloxetine is a selective serotonin reuptake (SSRI) inhibitor. This medicine mainly works by increasing the chemical messengers in the brain responsible for regulating pain.

Pregaba D 75/20 Capsule 10's can be taken with or without food or as prescribed by your doctor. Pregaba D 75/20 Capsule 10's may cause certain side effects such as nausea, constipation, headache, dry mouth, increased sweating, loss of appetite, dizziness, and burning sensation. These side effects do not require medical attention and gradually resolve over time. However, if any of these side effects persist, inform your doctor.

Pregaba D 75/20 Capsule 10's should be avoided if you are allergic to it. Inform your doctor if you have any liver or kidney disease, seizures (fits), mania, bipolar disorder, glaucoma (an eye condition), bleeding disorders, or are at risk of hyponatremia (low sodium levels, especially in patients taking diuretics or water pills). If you are pregnant or breastfeeding, inform your doctor before taking this medicine. It is not recommended for use in children and young adults as it increases the risk of suicidal tendencies. 

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Non returnable*
COD available

Online payment accepted

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

Uses of Pregaba D 75/20 Capsule 10's

Diabetic Neuropathic Pain, Fibromyalgia

Medicinal Benefits

Pregaba D 75/20 Capsule 10's contains Pregabalin and Duloxetine. Pregabalin belongs to an anticonvulsant class of drugs, whereas Duloxetine is a selective serotonin reuptake (SSRI) inhibitor. This medicine mainly works by increasing the chemical messengers in the brain responsible for regulating pain. Pregaba D 75/20 Capsule 10's effectively treats neuropathic pain, and improves nerve conduction for proper nerve signal functioning in the body. 

Side Effects of Pregaba D 75/20 Capsule 10's

  • Burning sensation
  • Drowsiness
  • Nausea
  • Constipation
  • Headache
  • Dry mouth
  • Increased sweating
  • Loss of appetite

Directions for Use

Take Pregaba D 75/20 Capsule 10's as prescribed by your doctor. Swallow it as a whole with water. It can be taken with or without food. Do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Pregaba D 75/20 Capsule 10's should be avoided if you are allergic to any of the components in it. Do not stop taking Pregaba D 75/20 Capsule 10's suddenly without your doctor’s advice, as it may cause withdrawal symptoms like dizziness, tingling sensation, sleep disturbances, restlessness, nausea or vomiting, headache, or excessive sweating. Inform your doctor if you have any liver or kidney disease, seizures (fits), mania, bipolar disorder, or glaucoma (an eye condition). Pregaba D 75/20 Capsule 10's may increase suicidal thoughts, so it is advised to use caution in patients with mania, bipolar disorder or depression. It is not recommended for use in children below 18 years of age as the safety and efficacy of this medicine are not established. Pregnant or breastfeeding mothers should inform the doctor before using Pregaba D 75/20 Capsule 10's.

Therapeutic Class

ANTICONVULSANT

Drug-Drug Interactions

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NortriptylineSelegiline
Critical
NortriptylineZiprasidone
Critical

Drug-Drug Interactions

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NortriptylineSelegiline
Critical
How does the drug interact with Pregaba D 75/20 Capsule 10's:
Co-administration of Pregaba D 75/20 Capsule 10's with Selegiline might raise serotonin hormone levels in the body (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Taking Pregaba D 75/20 Capsule 10's with Selegiline together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience confusion, hallucination, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
NortriptylineZiprasidone
Critical
How does the drug interact with Pregaba D 75/20 Capsule 10's:
Coadministration of Pregaba D 75/20 Capsule 10's with Ziprasidone can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Pregaba D 75/20 Capsule 10's with Ziprasidone together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, severe or prolonged diarrhea, or vomiting. Do not discontinue any medications without consulting a doctor.
NortriptylineSafinamide
Critical
How does the drug interact with Pregaba D 75/20 Capsule 10's:
Coadministration of Pregaba D 75/20 Capsule 10's with Safinamide may increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Pregaba D 75/20 Capsule 10's with Safinamide together can result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting your doctor.
NortriptylinePotassium citrate
Critical
How does the drug interact with Pregaba D 75/20 Capsule 10's:
Coadministration of Pregaba D 75/20 Capsule 10's with Potassium citrate can increase the risk or severity of gastric bleeding, ulceration, and rarely, perforation leading to serious blood loss.

How to manage the interaction:
Taking Pregaba D 75/20 Capsule 10's with Potassium citrate together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, dizziness, lightheadedness, abdominal pain, bloating, decreased hunger, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
NortriptylineLinezolid
Critical
How does the drug interact with Pregaba D 75/20 Capsule 10's:
Coadministration of Pregaba D 75/20 Capsule 10's with Linezolid might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to side effects.

How to manage the interaction:
Taking Pregaba D 75/20 Capsule 10's with Linezolid together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
NortriptylineTranylcypromine
Critical
How does the drug interact with Pregaba D 75/20 Capsule 10's:
Coadministration of Pregaba D 75/20 Capsule 10's with Tranylcypromine can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Pregaba D 75/20 Capsule 10's with Tranylcypromine together can result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
NortriptylineIsocarboxazid
Critical
How does the drug interact with Pregaba D 75/20 Capsule 10's:
Using Pregaba D 75/20 Capsule 10's together with Isocarboxazid can increase the risk of serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is especially a mood stabilizer).

How to manage the interaction:
Taking Isocarboxazid with Pregaba D 75/20 Capsule 10's is not recommended, please consult your doctor before taking it. However, if you experience increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasms or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea call a doctor. Do not discontinue any medications without consulting a doctor.
NortriptylineBepridil
Severe
How does the drug interact with Pregaba D 75/20 Capsule 10's:
Using bepridil together with Pregaba D 75/20 Capsule 10's can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
There may be a possibility of interaction between Pregaba D 75/20 Capsule 10's and Bepridil, but it can be taken if prescribed by a doctor. If you notice any of these signs, it's important to contact a doctor right away: your heart beating irregularly, feeling suddenly dizzy or lightheaded, fainting, or having a fast or strong heartbeat. Do not stop using any medications without talking to a doctor.
NortriptylineSotalol
Severe
How does the drug interact with Pregaba D 75/20 Capsule 10's:
Coadministration of Pregaba D 75/20 Capsule 10's with Sotalol can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Pregaba D 75/20 Capsule 10's with Sotalol together can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
NortriptylineIbutilide
Severe
How does the drug interact with Pregaba D 75/20 Capsule 10's:
Coadministration of Pregaba D 75/20 Capsule 10's with Ibutilide can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Pregaba D 75/20 Capsule 10's with Ibutilide together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, severe or prolonged diarrhea, or vomiting. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • TRAMADOL
  • FLUOXETINE
  • MOCLOBEMIDE
  • VENLAFAXINE
  • AMITRIPTYLINE

Diet & Lifestyle Advise

  • Exercise regularly, which helps in reducing pain.
  • Rest well, and get enough sleep.
  • Always take a warm bath, as it can be soothing.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity, and improves coping skills.

Habit Forming

Yes

Special Advise

  • Do not stop taking Pregaba D 75/20 Capsule 10's suddenly, as it may cause withdrawal symptoms.
  • Do frequent blood tests to check your fasting blood glucose, HbA1c, and total cholesterol (TC) levels to reduce any serious side effects.

Disease/Condition Glossary

Diabetic Neuropathy: Diabetic neuropathic pain/diabetic neuropathy is a condition causing moderate to severe pain due to damage of nerves in the thigh, hip, buttock and leg regions. Symptoms may include tingling, shooting pain, burning, or even an electric shock sensation. It mainly occurs in patients suffering from Type II Diabetes.

Fibromyalgia: It is a chronic condition with moderate pain and tenderness of the muscle all over the body. It mainly occurs due to physical or psychological stress. Symptoms may include fatigue, tiredness, trouble sleeping, anxiety, headache and depression.

Pregaba D 75/20 Capsule 10's Substitute

Substitutes safety advice
  • Maxdulin 75 mg/20 mg Capsule 10's

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    21.51per tablet
  • Pregabid D 75/20 Capsule 10's

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    21.47per tablet
  • Pregeb D 75/20 Capsule 10's

    by Others

    23.76per tablet
  • Pregalin D 75/20 Capsule 10's

    by Others

    21.60per tablet
  • Neurokem D 75 mg/20 mg Capsule 10's

    by Others

    21.42per tablet
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