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Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

Online payment accepted

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Whats That

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Manufacturer/Marketer

Eris Life Sciences Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Renerve DP 75/20 Capsule

Renerve DP 75/20 Capsule belongs to an anticonvulsant class of medicines. It is used in the treatment of diabetic neuropathic pain and fibromyalgia. Neuropathic pain/ peripheral neuropathy is pain that occurs when the nervous system is not working properly or is damaged. Diabetic neuropathic pain/diabetic neuropathy is a condition causing moderate to severe pain due to damage of nerves in the thigh, hip, buttock and leg regions. Symptoms may include tingling, shooting pain, burning, or even an electric shock sensation. Fibromyalgia is a chronic condition with moderate pain and tenderness all over the body resulting in fatigue and trouble sleeping.

Renerve DP 75/20 Capsule is a combination of Pregabalin and Duloxetine. Pregabalin belongs to an anticonvulsant class of drugs, whereas Duloxetine is a selective serotonin reuptake (SSRI) inhibitor. This medicine mainly works by increasing the chemical messengers in the brain responsible for regulating pain.

Renerve DP 75/20 Capsule can be taken with or without food or as prescribed by your doctor. Renerve DP 75/20 Capsule may cause certain side effects such as nausea, constipation, headache, dry mouth, increased sweating, loss of appetite, dizziness, and burning sensation. These side effects do not require medical attention and gradually resolve over time. However, if any of these side effects persist, inform your doctor.

Renerve DP 75/20 Capsule should be avoided if you are allergic to it. Inform your doctor if you have any liver or kidney disease, seizures (fits), mania, bipolar disorder, glaucoma (an eye condition), bleeding disorders, or are at risk of hyponatremia (low sodium levels, especially in patients taking diuretics or water pills). If you are pregnant or breastfeeding, inform your doctor before taking this medicine. It is not recommended for use in children and young adults as it increases the risk of suicidal tendencies. 

Uses of Renerve DP 75/20 Capsule

Diabetic Neuropathic Pain, Fibromyalgia

Directions for Use

Take Renerve DP 75/20 Capsule as prescribed by your doctor. Swallow it as a whole with water. It can be taken with or without food. Do not crush, break or chew it.

Medicinal Benefits

Renerve DP 75/20 Capsule contains Pregabalin and Duloxetine. Pregabalin belongs to an anticonvulsant class of drugs, whereas Duloxetine is a selective serotonin reuptake (SSRI) inhibitor. This medicine mainly works by increasing the chemical messengers in the brain responsible for regulating pain. Renerve DP 75/20 Capsule effectively treats neuropathic pain, and improves nerve conduction for proper nerve signal functioning in the body. 

Storage

Store in a cool and dry place away from sunlight

Side Effects of Renerve DP 75/20 Capsule

  • Burning sensation
  • Drowsiness
  • Nausea
  • Constipation
  • Headache
  • Dry mouth
  • Increased sweating
  • Loss of appetite

Drug Warnings

Renerve DP 75/20 Capsule should be avoided if you are allergic to any of the components in it. Do not stop taking Renerve DP 75/20 Capsule suddenly without your doctor’s advice, as it may cause withdrawal symptoms like dizziness, tingling sensation, sleep disturbances, restlessness, nausea or vomiting, headache, or excessive sweating. Inform your doctor if you have any liver or kidney disease, seizures (fits), mania, bipolar disorder, or glaucoma (an eye condition). Renerve DP 75/20 Capsule may increase suicidal thoughts, so it is advised to use caution in patients with mania, bipolar disorder or depression. It is not recommended for use in children below 18 years of age as the safety and efficacy of this medicine are not established. Pregnant or breastfeeding mothers should inform the doctor before using Renerve DP 75/20 Capsule .

Drug-Drug Interactions

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DuloxetineLinezolid
Critical
DuloxetineProcarbazine
Critical

Drug-Drug Interactions

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DuloxetineLinezolid
Critical
How does the drug interact with Renerve DP 75/20 Capsule:
Taking Renerve DP 75/20 Capsule with Linezolid can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although taking Renerve DP 75/20 Capsule with Linezolid is not recommended, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, shivering, blurred vision, pain in the muscles, stomach cramps, nausea, vomiting, and diarrhoea. Do not discontinue any medications without consulting a doctor.
DuloxetineProcarbazine
Critical
How does the drug interact with Renerve DP 75/20 Capsule:
Taking Renerve DP 75/20 Capsule with procarbazine can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Renerve DP 75/20 Capsule with Procarbazine is not recommended, but they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, shivering or shaking, pain in the muscles, stomach cramps, nausea, vomiting, and diarrhoea. Do not discontinue any medications without consulting your doctor.
DuloxetineEliglustat
Critical
How does the drug interact with Renerve DP 75/20 Capsule:
Coadministration of eliglustat and Renerve DP 75/20 Capsule can significantly increase the blood levels of eliglustat. This may increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Renerve DP 75/20 Capsule with Eliglustat is not recommended, but they can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, slow heart rate, or weak pulse. Do not discontinue any medications without consulting your doctor.
DuloxetineRasagiline
Critical
How does the drug interact with Renerve DP 75/20 Capsule:
Taking Rasagiline with Renerve DP 75/20 Capsule can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Rasagiline and Renerve DP 75/20 Capsule is not recommended as they can possibly result in an interaction, but they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, shivering, pain in the muscles, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting a doctor.
DuloxetinePhenelzine
Critical
How does the drug interact with Renerve DP 75/20 Capsule:
Taking phenelzine with Renerve DP 75/20 Capsule can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Renerve DP 75/20 Capsule with Phenelzine is not recommended, but they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, shivering, blurred vision, pain in the muscles, stomach cramps, nausea, vomiting, and diarrhoea. Do not discontinue any medications without consulting your doctor.
DuloxetineMetoclopramide
Critical
How does the drug interact with Renerve DP 75/20 Capsule:
Coadministration of metoclopramide with Renerve DP 75/20 Capsule increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Metoclopramide with Renerve DP 75/20 Capsule is not recommended, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
DuloxetineSafinamide
Critical
How does the drug interact with Renerve DP 75/20 Capsule:
Coadministration of safinamide with Renerve DP 75/20 Capsule can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Safinamide with Renerve DP 75/20 Capsule is not recommended as it can result in an interaction, but they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, shivering, pain in the muscles, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting a doctor.
DuloxetineSelegiline
Critical
How does the drug interact with Renerve DP 75/20 Capsule:
Taking Renerve DP 75/20 Capsule with selegiline may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Although there is an interaction between Renerve DP 75/20 Capsule and Selegiline, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, shivering, blurred vision, pain in the muscles, stomach cramps, nausea, vomiting, and diarrhoea. Do not discontinue any medications without consulting your doctor.
DuloxetineTranylcypromine
Critical
How does the drug interact with Renerve DP 75/20 Capsule:
Taking Tranylcypromine with Renerve DP 75/20 Capsule can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Tranylcypromine with Renerve DP 75/20 Capsule is not recommended but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, shivering, pain in the muscles or stiffness, stomach cramps, nausea, vomiting, and diarrhoea. Do not discontinue any medications without consulting your doctor.
PregabalinOxycodone
Severe
How does the drug interact with Renerve DP 75/20 Capsule:
Using Renerve DP 75/20 Capsule together with Oxycodone causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking oxycodone and Renerve DP 75/20 Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Exercise regularly, which helps in reducing pain.
  • Rest well, and get enough sleep.
  • Always take a warm bath, as it can be soothing.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity, and improves coping skills.

Habit Forming

Yes

Therapeutic Class

ANTICONVULSANT

Renerve DP 75/20 Capsule Substitute

Substitutes safety advice
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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Renerve DP 75/20 Capsule contains Pregabalin and Duloxetine. Pregabalin belongs to an anticonvulsant class of drugs, whereas Duloxetine is a selective serotonin reuptake (SSRI) inhibitor. This medicine mainly works by increasing the chemical messengers in the brain responsible for regulating pain.

Do not stop using Renerve DP 75/20 Capsule suddenly as it can cause withdrawal symptoms. Your doctor will gradually reduce the dose based on your clinical condition.

Seek medical attention immediately if you notice any depressive thoughts while using Renerve DP 75/20 Capsule . Your doctor may change the dose or medicine to treat your condition.

Neuropathic pain/ peripheral neuropathy is pain that occurs when the nervous system is not working properly or is damaged.

Drug-Drug Interactions Checker List

  • TRAMADOL
  • FLUOXETINE
  • MOCLOBEMIDE
  • VENLAFAXINE
  • AMITRIPTYLINE

Special Advise

  • Do not stop taking Renerve DP 75/20 Capsule suddenly, as it may cause withdrawal symptoms.
  • Do frequent blood tests to check your fasting blood glucose, HbA1c, and total cholesterol (TC) levels to reduce any serious side effects.

Disease/Condition Glossary

Diabetic Neuropathy: Diabetic neuropathic pain/diabetic neuropathy is a condition causing moderate to severe pain due to damage of nerves in the thigh, hip, buttock and leg regions. Symptoms may include tingling, shooting pain, burning, or even an electric shock sensation. It mainly occurs in patients suffering from Type II Diabetes.

Fibromyalgia: It is a chronic condition with moderate pain and tenderness of the muscle all over the body. It mainly occurs due to physical or psychological stress. Symptoms may include fatigue, tiredness, trouble sleeping, anxiety, headache and depression.

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