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Written By Divya L , PharmaD
Reviewed By Santoshini Reddy G , M Pharmacy
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About Pronova Capsule

Pronova Capsule is a combination medication indicated for the management of neuropathic pain. Neuropathic pain is a chronic progressive nerve disease that causes nerve pain due to nerve damage or a malfunctioning nervous system. Symptoms of neuropathic pain include shooting, burning pain followed by tingling and numbness (loss of sensation). Neuropathic pain can be caused due to amputation of limbs, diabetic neuropathy (nerve damage due to excess blood sugar level), excessive alcohol intake (alcoholism) and cancer treatment via chemotherapy.

Pronova Capsule contains Pregabalin (anticonvulsant), Methylcobalamin (vitamin B12), Alpha-lipoic acid (antioxidant), Pyridoxine hydrochloride (vitamin B6), and Folic acid (vitamin B9). Pregabalin affects the chemicals in the brain that send pain signals to the nervous system, thereby relieving nerve pain and lowering the risk of seizures (fits). Methylcobalamin and Pyridoxine hydrochloride help in the rejuvenation and protection of damaged nerve cells by producing a substance called myelin. Alpha-lipoic acid helps in providing a protective effect on the nerve tissues and the brain. Folic acid helps in delivering essential nutrients to the nerves. Together, Pronova Capsule provides relief from neuropathic pain.

Use Pronova Capsule as prescribed by your doctor. In some cases, you may experience certain common side effects, such as dizziness, sleepiness, tiredness, nausea, and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Please do not stop taking Pronova Capsule without consulting your doctor, as it could cause withdrawal symptoms. Consult your doctor before starting Pronova Capsule if you are pregnant or breastfeeding. Pronova Capsule may cause drowsiness and dizziness, so drive only if you are alert. Avoid consuming alcohol along with Pronova Capsule as it could lead to increased dizziness and sleepiness. Pronova Capsule should not be given to children as safety and effectiveness have not been established.

Uses of Pronova Capsule

Neuropathic pain.

Directions for Use

Swallow it as a whole with a glass of water; do not chew, crush or break it.

Medicinal Benefits

Pronova Capsule is a combination of five drugs: Pregabalin (anti-convulsant or antiepileptic), methylcobalamin (vitamin B12), alpha-lipoic acid (antioxidant), pyridoxine hydrochloride (vitamin B6), and folic acid (vitamin B9). Pronova Capsule is used to treat neuropathic pain. Pregabalin affects the chemicals in the brain that send pain signals to the nervous system, thereby relieving nerve pain and lowering the risk of seizures. Methylcobalamin and Pyridoxine hydrochloride help in the rejuvenation and protection of damaged nerve cells by producing a substance called myelin. Alpha-lipoic acid helps in providing a protective effect on the nerve tissues and brain. Folic acid helps in providing essential nutrients to the nerves. Together, Pronova Capsule helps in providing relief from neuropathic pain.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Pronova Capsule

  • Dizziness
  • Sleepiness
  • Tiredness
  • Nausea
  • Vomiting

Drug Warnings

Do not take Pronova Capsule if you are allergic to any of its contents. Inform your doctor before taking Pronova Capsule if you have/had heart problems or bipolar syndrome. Please do not stop taking Pronova Capsule without consulting your doctor as it could cause withdrawal symptoms. Do not take Pronova Capsule if you are pregnant or breastfeeding unless prescribed by the doctor. Pronova Capsule causes drowsiness and dizziness, so drive only if you are alert. Avoid consuming alcohol along with Pronova Capsule as it could lead to increased dizziness and sleepiness. Pronova Capsule should not be given to children as safety and effectiveness have not been established. Consult your doctor immediately if you experience suicidal tendencies.

Drug-Drug Interactions

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PregabalinNalbuphine
Severe
PregabalinBuprenorphine
Severe

Drug-Drug Interactions

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PregabalinNalbuphine
Severe
How does the drug interact with Pronova Capsule:
Using Pronova Capsule together with Nalbuphine causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking Nalbuphine and Pronova Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinBuprenorphine
Severe
How does the drug interact with Pronova Capsule:
Using Pronova Capsule together with Buprenorphine causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Buprenorphine and Pronova Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, and impairment in- judgment, reaction speed and motor coordination, consult the doctor immediately. Avoid driving or operating dangerous machinery. Do not exceed the doses, frequency, or duration of usage advised by the doctor. Do not discontinue any medications without consulting a doctor.
PregabalinSodium oxybate
Severe
How does the drug interact with Pronova Capsule:
Using Sodium oxybate together with Pronova Capsule may increase the risk of side effects.

How to manage the interaction:
Although taking Pronova Capsule with Sodium oxybate together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience drowsiness, dizziness, lightheadedness, confusion, slow or shallow breathing, and impairment in thinking, judgment, and motor coordination, consult the doctor. For at least six hours after taking sodium oxybate, avoid operating machinery or engaging in potentially dangerous activities. Also, be careful when getting up from a sitting or lying down posture. Do not stop using any medications without talking to a doctor.
PregabalinKetamine
Severe
How does the drug interact with Pronova Capsule:
Taking Ketamine with Pronova Capsule may increase the risk of side effects.

How to manage the interaction:
Although taking Pronova Capsule and ketamine together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience symptoms such as dizziness, drowsiness, confusion, difficulty concentrating, breathing difficulty, consult the doctor. Do not exceed the doses, frequency, or duration of usage advised by a doctor. You should avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinMethadone
Severe
How does the drug interact with Pronova Capsule:
Using Pronova Capsule together with Methadone causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking methadone and Pronova Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinRemifentanil
Severe
How does the drug interact with Pronova Capsule:
Using Pronova Capsule together with Remifentanil causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking remifentanil and Pronova Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinSufentanil
Severe
How does the drug interact with Pronova Capsule:
Using Pronova Capsule together with Sufentanil causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking sufentanil and Pronova Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinTapentadol
Severe
How does the drug interact with Pronova Capsule:
Using Tapentadol together with Pronova Capsule may cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Taking Pronova Capsule with Tapentadol can result in an interaction, it can be taken if a doctor has advised it. Contact a doctor immediately if you experience signs such as drowsiness, lightheadedness, palpitations, confusion, severe weakness, or difficulty breathing. Do not exceed the doses or frequency and duration of use advised by the doctor. Do not discontinue any medications without consulting a doctor.
PregabalinCodeine
Severe
How does the drug interact with Pronova Capsule:
Using Pronova Capsule together with Codeine may cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Codeine and Pronova Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinOxycodone
Severe
How does the drug interact with Pronova Capsule:
Using Pronova Capsule together with Oxycodone causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking oxycodone and Pronova Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include food rich in vitamin B and D in your diet.
  • Include cayenne pepper in your diet as it can help in lowering neuropathic pain.
  • Exercising regularly helps in improving overall health and combating pain. 
  • Rest well, and get plenty of sleep.
  • Try taking a warm bath as it can be soothing.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity and improves coping skills.
  • Acupuncture can be helpful by stimulating pressure points.
  • Using essential oils for massages can help increase circulation.

Habit Forming

No

Therapeutic Class

MISCELLANEOUS

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • AMITRIPTYLINE
  • DULOXETINE
  • CODEINE
  • MORPHINE
  • TRAMADOL
  • GABAPENTIN
  • PHENOBARBITAL
  • DIAZEPAM
  • METFORMIN
  • METHOTREXATE
  • SULFASALAZINE
  • CHLORAMPHENICOL
  • ALTRETAMINE
  • LEVODOPA

Disease/Condition Glossary

Neuropathic pain: It is a nervous disorder that occurs due to nerve damage caused by chronic progressive nerve disease, limb amputation, diabetes or due to infection or injury. The pain could be intermittent or continuous, felt as a prickling, stabbing, tingling or burning sensation. A feeling of numbness and loss of sensation is also common with neuropathic pain. Usually, the body sends the pain signals when there is an injury, but with neuropathic pain, the pain that is not triggered by an injury, the body sends the pain signals unpromptedly. Symptoms include spontaneous, un-triggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping, and evoked pain (pain caused by events that are usually not painful).

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