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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
COD available

Online payment accepted

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Manufacturer/Marketer :

Ikon Remedies Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Rabepraz DM Tablet

Rabepraz DM Tablet is a gastrointestinal medicine composed of Rabeprazole (stomach acid reducer) and Domperidone (nausea/vomiting reducer). Together they reduce the amount of acid your stomach makes and decrease the symptoms of nausea and vomiting. It treats symptoms of acid reflux due to hyperacidity, stomach ulcer (Peptic ulcer disease), and Zollinger Ellison syndrome (overproduction of acid due to a pancreatic tumour). Besides this, it is used short-term to treat gastroesophageal reflux disease (GERD) symptoms. GERD is a condition in which the sphincter (valve) located at the uppermost part of the stomach gets irritated and damaged due to excessive stomach acid production. As a result, the stomach acid and juice flow back into the food pipe, leading to stomach upset and heartburn. Heartburn is the post-effect of acid reflux with a burning-like feeling that rises from the stomach towards the neck.

Rabepraz DM Tablet contains two medicines, namely Rabeprazole and Domperidone. Rabeprazole is a proton pump inhibitor that helps reduce stomach acid by blocking the actions of an enzyme (H+/K+ ATPase or gastric proton pump). This gastric proton pump lies in the cells of the stomach wall. It is responsible for releasing gastric acid secretion and damaging tissues in the food pipe, stomach, and duodenum (uppermost part of the small intestine). On the other hand, Domperidone is a prokinetic agent that increases the motility of the upper gastrointestinal tract and blocks the vomiting-inducing centre (chemoreceptor trigger zone-CTZ).

It is better to take Rabepraz DM Tablet an hour before a meal or without a meal for its best results. Rabepraz DM Tablet should be swallowed whole with a glass of water. Do not chew, crush, or break it. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early, your symptoms may come back, and your condition may worsen. An adult taking Rabepraz DM Tablet might have common side effects like headache, diarrhoea, nausea, abdominal pain, vomiting, flatulence, dizziness, and arthralgia (joint pain). In the case of children taking Rabepraz DM Tablet might report upper respiratory tract infections (URI), headache, fever, diarrhoea, vomiting, rash, and abdominal pain. These side effects are temporary and may resolve after some time; however, if this persists, contact the doctor.

You can increase the efficacy of Rabepraz DM Tablet by taking a small meal or snacks frequently. Avoid caffeine-containing beverages (coffee, tea), spicy/deep-fried/processed foods, carbonated drinks, and acidic foods like citrus fruits/vegetables (tomatoes). Tell your doctor if you have stomach or intestinal cancer, liver problem, are allergic to Rabepraz DM Tablet or will have an endoscopy in the future. Prolonged intake of Rabepraz DM Tablet may cause deficiency of Vitamin B-12 and low levels of calcium, magnesium, and Vitamin D leading to osteoporosis (brittle or weak bones).

Uses of Rabepraz DM Tablet

Gastro-Esophagal Reflux Disease (GERD), Acid reflux, Heartburn, Peptic ulcer, stomach ulcers, Dyspepsia (stomach discomfort due to indigestion).

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Rabepraz DM Tablet helps in reducing the excess amount of stomach. In turn, it prevents the formation of an ulcer in the upper part of the intestine (duodenal ulcer), gastro-esophagal reflux disease (GERD) with or without ulcer and Zollinger-Ellison Syndrome, in which the stomach makes exceptionally high amounts of acid. Besides, the Rabepraz DM Tablet also treats symptoms of nausea and vomiting in adults and children over 12 years of age (with at least 35 kg or more).

Storage

Keep Rabepraz DM Tablet out of the sight and reach of children.
Side effects of Rabepraz DM Tablet
Here are the steps to manage the medication-triggered Cough:
  • Tell your doctor about the cough symptoms you're experiencing, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your cough symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids, such as water, tea, or soup, to help thin out mucus and soothe your throat.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your cough persists or worsens, consult your doctor for further guidance.
  • Drink warm fluids such as warm water with honey, broth, soup or herbal tea to soothe sore throat.
  • Gargle with warm salt water.
  • Suck on lozenges to increase the production of saliva and soothe your throat.
  • Use a humidifier to soothe sore throat as it adds moisture to the air and makes breathing easier.
  • To help reduce symptoms, eat foods high in vitamin C, such as oranges, bell peppers and strawberries.
  • Lightly blow your nose to remove mucus; steer clear of blowing hard.
  • Infections can be prevented from spreading by washing hands frequently and staying away from other people.
  • If you have allergies, do your best to avoid triggering allergens that could contribute to a runny nose.
  • Don't smoke, as irritating the nasal passages can make a runny nose worse.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Managing back pain as a side effect of medication requires a combination of self-care techniques, lifestyle modifications, and medical interventions. Here are the steps:
  • Talk to your doctor about your back pain and potential medication substitutes or dose changes.
  • Try yoga or Pilates and other mild stretching exercises to increase flexibility and strengthen your back muscles.
  • To lessen the tension on your back, sit and stand upright and maintain proper posture.
  • To alleviate discomfort and minimize inflammation, apply heat or cold packs to the afflicted area.
  • Under your doctor's supervision, think about taking over-the-counter painkillers like acetaminophen or ibuprofen.
  • Make ergonomic adjustments to your workspace and daily activities to reduce strain on your back.
  • To handle tension that could make back pain worse, try stress-reduction methods like deep breathing or meditation.
  • Use pillows and a supportive mattress to keep your spine in the right posture as you sleep.
  • Back discomfort can worsen by bending, twisting, and heavy lifting.
  • Speak with a physical therapist to create a customized training regimen to increase back strength and flexibility.

Drug Warnings

You should avoid taking Rabepraz DM Tablet if you are allergic to Rabepraz DM Tablet or proton pump inhibitors, have gastric cancer, liver disease, low magnesium level (osteoporosis), low vitamin B12, are pregnant or planning for pregnancy, and breastfeeding mothers. Rabepraz DM Tablet may interact with a blood thinner (warfarin), antifungal (ketoconazole), anti-HIV drug (atazanavir, nelfinavir), iron supplements, ampicillin antibiotic, anti-cancer drug (methotrexate). Let your doctor know if you are taking these medicines. Prolonged intake of Rabepraz DM Tablet may cause lupus erythematosus (an inflammatory condition in which the immune system attacks its tissues), Vitamin B-12, and magnesium deficiency. Intake of Rabepraz DM Tablet may mask the symptom of gastric cancer, so if you have any severe stomach pain or gastric bleeding (blood in mucous or stool), immediately consult the doctor. Tell your doctor that you are using before having a specific blood test known as Chromogranin A.

Drug-Drug Interactions

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RabeprazoleRilpivirine
Critical

Drug-Drug Interactions

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RabeprazoleRilpivirine
Critical
How does the drug interact with Rabepraz DM Tablet:
Co-administration of Rabepraz DM Tablet can make Rilpivirine less effective by reducing its absorption in the body.

How to manage the interaction:
Taking Rabepraz DM Tablet with Rilpivirine is not recommended, but can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.
How does the drug interact with Rabepraz DM Tablet:
When used in combination with erlotinib, Rabepraz DM Tablet may prevent the absorption of erlotinib into the circulation, which might make erlotinib less effective in treating cancer.

How to manage the interaction:
Taking Rabepraz DM Tablet with Erlotinib is not recommended as it can result in an interaction, it should be taken only if a doctor has advised it. Do not stop using any medications without consulting a doctor.
DomperidoneHalofantrine
Severe
How does the drug interact with Rabepraz DM Tablet:
Coadministration of Rabepraz DM Tablet with Halofantrine can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Rabepraz DM Tablet and Halofantrine together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneToremifene
Severe
How does the drug interact with Rabepraz DM Tablet:
Coadministration of Rabepraz DM Tablet with Toremifene can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Rabepraz DM Tablet and Toremifene together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Rabepraz DM Tablet:
Coadministration of Rabepraz DM Tablet with Cisapride can increase the blood levels of Rabepraz DM Tablet.

How to manage the interaction:
There may be a possibility of interaction between Rabepraz DM Tablet and Cisapride, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.
How does the drug interact with Rabepraz DM Tablet:
Coadministration of Rabepraz DM Tablet with Citalopram can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Rabepraz DM Tablet and Citalopram together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Rabepraz DM Tablet:
Coadministration of Rabepraz DM Tablet with Clarithromycin can increase the risk of side effects.

How to manage the interaction:
There may be a possibility of interaction between Rabepraz DM Tablet and Clarithromycin, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Rabepraz DM Tablet:
Coadministration of Rabepraz DM Tablet with Ketoconazole can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Rabepraz DM Tablet and Ketoconazole together can cause an interaction, it can be taken if a doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneBepridil
Severe
How does the drug interact with Rabepraz DM Tablet:
Co-administration of Domeperidone and Bepridil can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Rabepraz DM Tablet and Bepridil together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneMethadone
Severe
How does the drug interact with Rabepraz DM Tablet:
Coadministration of Rabepraz DM Tablet with Methadone can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Rabepraz DM Tablet and Methadone together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid intake of acid or heartburn-triggering foods or drinks like onions, peppermint, chocolate, caffeinated beverages, citrus fruits or juices, tomatoes and high-fat and spicy foods.
  • Avoid taking alcohol and smoking cigarette. Alcohol can raise the level of production of stomach acid leading to heartburn and acid reflux. On the other hand, nicotine smoking damages the valve (sphincter), preventing stomach acid backflow into the food pipe.
  • Avoid regular sitting continuously, as it can increase stomach acid production. Try to take a break of 5 minutes in 1 hour by brisk walking or stretching.
  • Before going to sleep, try to raise your bedhead so that your head and chest are higher than your feet. Do not use piles of pillows, instead, one raised block is fine. This will not allow the stomach acid to backflow through your food pipe.
  • Include high fibre containing foods, berries, cherries, leafy green veggies (kale, spinach) and black peppers in your meal. These foods are full of antioxidants, calcium and vitamin B 12 that can help cope with the long-term effects of the medicine. Fermented dairy products like miso, sauerkraut, and kimchi contain probiotics which help in the prevention of excess stomach acid production. Cranberry juice can be beneficial in the peptic ulcer and H Pylori infection.

Side Effects of Rabepraz DM Tablet

  • Rash
  • Brittle bones
  • Low vitamin B-12
  • Loss of libido (sexual desire)
  • Cough
  • Sore throat
  • Runny nose
  • Flatulence (gas formation)
  • Back pain
  • Weakness or loss of strength
  • Sleeplessness
  • Headache
  • Dizziness
  • Benign polyps in the stomach

Habit Forming

No

Therapeutic Class

GASTROINTESTINAL AGENTS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

No. Rabepraz DM Tablet prevents excess production of stomach acid causing acid reflux and heartburn. If blood is coming in your stool or mucous immediately contact the doctor.

Yes, Rabepraz DM Tablet can cause dry mouth and it is due to domperidone. In case you fell excessive thirsty, please increase your fluid intake and do frequent mouth rinses.

Diarrhoea might be a side-effect of Rabepraz DM Tablet . Drink enough fluids and eat non-spicy food if you experience diarrhoea. Consult your doctor if you have severe diarrhoea or any other discomfort.

Avoid lying down immediately after meals to prevent acid reflux. Raise the head of the bed 10-20cm by putting on a pillow so that the head and chest are above the waist. This helps in preventing acid reflux.

Drug-Drug Interactions Checker List

  • CLOPIDOGREL
  • WARFARIN
  • KETOCONAZOLE
  • VORICONAZOLE
  • ITRACONAZOLE
  • FLUCONAZOLE
  • ATAZANAVIR
  • AMPRENAVIR
  • NELFINAVIR
  • MAGNESIUM+ALUMINIUM HYDROXIDE
  • CIMETIDINE
  • IRON
  • ERYTHROMYCIN
  • RIFAMPICIN
  • ATROPINE
  • DIGOXIN
  • AMIODARONE
  • DILTIAZEM
  • METHOTREXATE
  • CLARITHROMYCIN

Special Advise

  • Do not take Rabepraz DM Tablet for more than four weeks of duration without consulting the doctor.

Disease/Condition Glossary

Usually, a thick layer of mucous usually protects the stomach against its acid secretion. But, in the long run, it gets eroded by excessive stomach acid production leading to complications like GERD, peptic ulcer, and Zollinger Ellison syndrome. Gastroesophageal reflux disease (GERD) is a gastrointestinal problem that occurs when stomach acid frequently flows back into the food pipe (oesophagus). This backflow (acid reflux) irritates the food pipe that causes heartburn. On the other hand, a peptic ulcer is a painful condition followed by the development of sores or ulcers in the stomach lining or duodenum (first part of the small intestine) (the duodenum). Zollinger Ellison syndrome is a rare condition in which a gastrin-secreting pancreas tumour causes excessive acid production leading to peptic ulcers.

Have a query?

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Alcohol

Caution

Drinking alcohol with Rabepraz DM Tablet may cause dehydration and elevate the level of stomach acid, thereby decreasing its efficiency. So try to avoid, limit alcohol or contact a doctor before intake of Rabepraz DM Tablet .

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Pregnancy

Caution

It is not known whether the Rabepraz DM Tablet affects the baby or not. So, contact a doctor before intake of Rabepraz DM Tablet . Your doctor will weigh the benefits and potential risks before prescribing them.

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Breast Feeding

Caution

Domperidone present in Rabepraz DM Tablet passes into the breast milk. However, no evidence of risk has been reported. Please consult your doctor before intake of Rabepraz DM Tablet . Your doctor will weigh the benefits and potential risks before prescribing them.

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Driving

Caution

In some cases, Rabepraz DM Tablet may cause dizziness, sleepy, or blur vision. If you observe these symptoms do not drive or operate heavy machinery until you feel better.

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Liver

Caution

If u have or had history or evidence of any liver-related diseases, please consult the doctor before taking medicine.

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Kidney

Caution

If u have or had history or evidence of any kidney-related diseases, please consult the doctor before taking medicine.

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Children

Caution

Rabepraz DM Tablet is not recommended for use in children due to a lack of data on safety and efficacy. Please consult your doctor.

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