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  1. Home
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  3. Rantac D Tablet 20's

Rantac D Tablet 20's, Pack of 20 TABLETS
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Non returnable*
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Whats That

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Composition :

DOMPERIDONE-10MG + RANITIDINE-150MG

Manufacturer/Marketer :

J B Chemicals & Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Rantac D Tablet

Rantac D Tablet belongs to a group of medicines called gastrointestinal agents used to treat gastro-oesophageal reflux disease (GERD) and peptic ulcers. Gastroesophageal reflux disease (GERD) occurs when stomach acid frequently flows back into the food pipe (oesophagus). Peptic ulcers are sores that develop on the inner lining of the intestine and stomach.

Rantac D Tablet is a combination of two drugs, namely: Ranitidine (H2 receptor antagonist) and Domperidone (a dopamine antagonist). Ranitidine works by blocking histamine H2 receptors located on the stomach lining, thereby reducing gastric acid secretion. Domperidone works by increasing the movements and contractions of stomach muscles. Together, Rantac D Tablet helps in treating acidity.

You are advised to take Rantac D Tablet for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side-effects such as dry mouth, stomach pain, constipation, headache, sleepiness, and dizziness. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Consult your doctor if you are pregnant or breastfeeding. Rantac D Tablet may cause sleepiness and dizziness, so drive only if you are alert. Rantac D Tablet should not be given to children as safety has not been established. Avoid consuming alcohol along with Rantac D Tablet as it could lead to increased drowsiness and can elevate the production of stomach acid. Keep your doctor informed about all the medicines and your health condition to rule out any side-effects.

Uses of Rantac D Tablet

Gastro-oesophageal reflux disease, peptic ulcers.

Directions for Use

Take Rantac D Tablet 30-60 minutes prior food. Swallow Rantac D Tablet as a whole with a glass of water; do not chew, or crush it.

Medicinal Benefits

Rantac D Tablet belongs to a group of medicines called gastrointestinal agents used to treat gastro-oesophageal reflux disease (GERD) and peptic ulcers. Rantac D Tablet is a combination of two drugs, namely: Ranitidine (H2 receptor antagonist) and Domperidone (a dopamine antagonist). Ranitidine works by blocking histamine H2 receptors located on the stomach lining, thereby reduces gastric acid secretion. Domperidone works by increasing the movements and contractions of stomach muscle. Together, Rantac D Tablet helps in treating acidity.

Storage

Keep Rantac D Tablet out of reach and sight of children.

Drug Warnings

Do not take Rantac D Tablet if you are allergic to any of its contents. Inform your doctor before taking Rantac D Tablet if you have a history of gastrointestinal bleeding, porphyria, or intestinal obstruction. Rantac D Tablet may cause B12 deficiency in long-term treatment. Consult your doctor if you are pregnant or breastfeeding. Rantac D Tablet may cause sleepiness and dizziness, so drive only if you are alert. Rantac D Tablet should not be given to children as safety has not been established. Avoid consuming alcohol along with Rantac D Tablet as it could lead to increased drowsiness and can elevate the production of stomach acid.

Drug-Drug Interactions

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RanitidineDasatinib
Severe
RanitidineAtazanavir
Severe

Drug-Drug Interactions

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RanitidineDasatinib
Severe
How does the drug interact with Rantac D Tablet:
Taking Rantac D Tablet and Dasatinib together reduces the effectiveness of Dasatinib.

How to manage the interaction:
Although taking Rantac D Tablet together with Dasatinib can result in an interaction, they can be taken together if prescribed by a doctor. However, contact a doctor if you experience any unusual symptoms. Do not discontinue any medicine without consulting a doctor.
RanitidineAtazanavir
Severe
How does the drug interact with Rantac D Tablet:
Taking atazanavir with Rantac D Tablet can reduce the effectiveness of atazanavir.

How to manage the interaction:
Although taking Rantac D Tablet together with Atazanavir can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor if you experience unusual symptoms. Do not discontinue any medicine without consulting a doctor.
RanitidineRilpivirine
Severe
How does the drug interact with Rantac D Tablet:
Coadministration of Rilpivirine with Rantac D Tablet can reduce the acidity levels in the stomach and also decrease the effectiveness of Rilpivirine.

How to manage the interaction:
Although taking Rantac D Tablet together with Rilpivirine can possibly result in an interaction, they can be taken together if prescribed by your doctor. To reduce the chance of interaction, take Rantac D Tablet at least 12 hours before or 4 hours after taking rilpivirine. Do not discontinue any medicine without consulting a doctor.
RanitidinePazopanib
Severe
How does the drug interact with Rantac D Tablet:
Using Pazopanib with Rantac D Tablet can reduce the effectiveness of pazopanib

How to manage the interaction:
Although taking Rantac D Tablet together with Pazopanib can possibly result in an interaction, but can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
RanitidineLoperamide
Severe
How does the drug interact with Rantac D Tablet:
Coadministration of loperamide with Rantac D Tablet may significantly increase the blood levels of loperamide. This can increase the risk of serious side effect like irregular heart rhythm.

How to manage the interaction:
Although taking loperamide with Rantac D Tablet together can result in an interaction, they can be taken if a doctor has prescribed it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
RanitidineGefitinib
Severe
How does the drug interact with Rantac D Tablet:
Coadministration of Gefitinib with Rantac D Tablet can reduce the acidity levels in the stomach and also decrease the effectiveness of gefitinib

How to manage the interaction:
Taking Gefitinib with Rantac D Tablet together can possibly result in an interaction, it can be taken if your doctor has advised it. It is recommended that gefitinib is either taken 6 hours before or 6 hours after Rantac D Tablet to help minimize the impact of the interaction. Do not stop using any medications without first talking to your doctor.
RanitidineMesalazine
Severe
How does the drug interact with Rantac D Tablet:
Co-administration of Rantac D Tablet with Mesalazine can decrease the levels of Mesalazine, which may be less effective in treating a condition.

How to manage the interaction:
There may be a possible interaction between Mesalazine with Rantac D Tablet, but they can be taken together if a doctor has prescribed them. Do not discontinue any medications without consulting a doctor.
DomperidoneKetoconazole
Severe
How does the drug interact with Rantac D Tablet:
Coadministration of Rantac D Tablet with Ketoconazole can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Rantac D Tablet and Ketoconazole together can cause an interaction, it can be taken if a doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneCisapride
Severe
How does the drug interact with Rantac D Tablet:
Coadministration of Rantac D Tablet with Cisapride can increase the blood levels of Rantac D Tablet.

How to manage the interaction:
There may be a possibility of interaction between Rantac D Tablet and Cisapride, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.
DomperidoneNefazodone
Severe
How does the drug interact with Rantac D Tablet:
Coadministration of Rantac D Tablet with Nefazodone can increase the blood levels of Rantac D Tablet.

How to manage the interaction:
There may be a possibility of interaction between Rantac D Tablet and Nefazodone, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat smaller meals more often.
  • Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increases acidity and heartburn.
  • Maintain a healthy weight by regular exercising.
  • Avoid lying down after eating.
  • Avoid tight-fitting clothes.
  • Maintain a healthy weight by regular exercising.
  • Practise relaxation techniques and avoid stress by doing yoga or meditation.
  • Avoid foods such as high-fat food, spicy food, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea and soda. 
  • Avoid sitting continuously as it may trigger acidity. Take a break of 5 minutes every hour by doing brisk walking or stretching.

Habit Forming

No

Therapeutic Class

GASTROINTESTINAL AGENTS

Rantac D Tablet Substitute

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 8, 2025 | 9:31 AM IST

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Rantac D Tablet is a combination of two drugs, namely: Ranitidine (H2 receptor antagonist) and Domperidone (a dopamine antagonist). Ranitidine works by blocking histamine H2 receptors located on the stomach lining, thereby reduces gastric acid secretion. Domperidone works by increasing the movements and contractions of stomach muscle. Together, Rantac D Tablet helps in treating acidity.

Talk to your doctor if you do not feel better even after taking Rantac D Tablet for 7 days. Do not take Rantac D Tablet for longer durations unless prescribed by the doctor.

Constipation might be a side-effect of Rantac D Tablet . Drink enough fluids and eat fibre rich food if you experience constipation.

Avoid lying down immediately after meals to prevent acid reflux. Raise the head of the bed 10-20cm by putting a pillow so that the head and chest are above the waist. This helps in preventing acid reflux.

Dry mouth could be a side-effect of Rantac D Tablet . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help in stimulating saliva and thereby prevents drying of the mouth.

Rantac D Tablet contains domperidone which helps in treating nausea and vomiting. However, Rantac D Tablet is used to treat acidity. Please consult your doctor, he/she may prescribe you an alternate medicine for treating nausea and vomiting.

Drug-Drug Interactions Checker List

  • ACETAMINOPHEN
  • NAPROXEN
  • ASPIRIN
  • IBUPROFEN
  • METHADONE
  • DULOXETINE
  • CITALOPRAM
  • ESCITALOPRAM
  • CYANOCOBALAMIN
  • KETOCONAZOLE
  • FLUCONAZOLE
  • VORICONAZOLE
  • ERYTHROMYCIN
  • CLARITHROMYCIN
  • TELITHROMYCIN
  • MOXIFLOXACIN
  • PROPRANOLOL
  • PROCAINAMIDE
  • AMIODARONE
  • DRONEDARONE
  • QUINIDINE
  • DISOPYRAMIDE
  • DOFETILIDE
  • SOTALOL
  • DILTIAZEM
  • VERAPAMIL
  • HALOPERIDOL
  • PIMOZIDE
  • SERTINDOLE
  • CISAPRIDE
  • DOLASETRON
  • MIZOLASTINE
  • VANDETANIB
  • DIAZEPAM
  • PHENYTOIN
  • THEOPHYLLINE
  • WARFARIN
  • GLIPIZIDE
  • HALOFANTRINE
  • TELAPREVIR
  • TOREMIFENE
  • VINCAMINE
  • DIPHEMANIL
  • MEQUITAZINE

Disease/Condition Glossary

Gastroesophageal reflux disease (GERD): It occurs when stomach acid frequently flows back into the food pipe (oesophagus). This backflow (acid reflux) irritates the food pipe and causes heartburn. Symptoms include heartburn, sour or bitter taste in the mouth, and difficulty swallowing.

Peptic ulcers: Peptic ulcers are sores that develop on the lining of the stomach and intestine due to erosion of stomach's protective lining. Symptoms include nausea, changes in appetite, bloody or dark stools, unexplained weight loss, vomiting, and indigestion.

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