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Reviewed By Sunny S , MBBS
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Composition :

RANOLAZINE-500MG

Manufacturer/Marketer :

Maxford Healthcare

Consume Type :

ORAL

Return Policy :

Not Returnable

About Renulaz 500SR Tablet 10's

Renulaz 500SR Tablet 10's belongs to the class of anti-anginal medications. It is used alone or with other medicines to treat angina pectoris. Angina pectoris is discomfort in the chest or chest pain, which generally occurs due to coronary artery disease (CAD) when an adequate amount of oxygen and blood is not reaching the heart and its muscles. It can also be due to the blockage of the heart's arteries. It helps prevent any further attack of angina by making the heart work more efficiently, and it is used as an add-on to existing treatment in patients whose disease is not adequately controlled by other medicines for angina pectoris, such as beta-blockers or calcium antagonists, or in patients who cannot take these medicines.

The active substance in Renulaz 500SR Tablet 10's is Ranolazine, which reduces sodium ions flow into the heart muscle cells. This interferes with the activity of special channels on the cell surface called 'sodium-dependent calcium channels through which calcium ions normally enter the cells. This reduces the number of calcium ions that enter the cells. Calcium ions normally cause the heart muscle to contract. By reducing the flow of calcium into the cells, Renulaz 500SR Tablet 10's is thought to help the heart to relax, improving blood flow to the heart muscle and relieving the symptoms of angina pectoris.

Your doctor will tell you how to take the Renulaz 500SR Tablet 10's based on your medical condition. You may sometimes experience constipation, dizziness, headache, or feeling sick. Most of these side effects of Renulaz 500SR Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Do not consume Renulaz 500SR Tablet 10's if you are allergic to any component in this medicine. Renulaz 500SR Tablet 10's should not be stopped even if you feel better for the best results as it prevents any future harm. If you stop taking the Renulaz 500SR Tablet 10's on your own, your chest pain can come back in more severe form. If you plan to get pregnant or are pregnant or breastfeeding, please consult your doctor to avoid any unwanted harm to the baby. Some lifestyle modifications are important for best results when taking Renulaz 500SR Tablet 10's like smoking cessation, decreasing alcohol intake, eating well, regular exercise, and managing stress. Renulaz 500SR Tablet 10's should be taken with caution if you have any liver or kidney problems. Also, inform your doctor if you are taking other medications to avoid unwanted side effects or contraindications.

Uses of Renulaz 500SR Tablet 10's

Angina Pectoris

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Renulaz 500SR Tablet 10's is prescribed for treating angina. Renulaz 500SR Tablet 10's is an anti-anginal medication used to treat angina pectoris. It reduces sodium ions' flow into the heart muscle cells. This interferes with the activity of special channels on the cell surface called ‘sodium-dependent calcium channels’ through which calcium ions normally enter the cells. This reduces the number of calcium ions that enter the cells. Calcium ions normally cause the heart muscle to contract. By reducing the flow of calcium into the cells, Renulaz 500SR Tablet 10's is thought to help the heart to relax, improving blood flow to the heart muscle and relieving the symptoms of angina pectoris.

Storage

Store in a cool and dry place away from sunlight
Side effects of Renulaz 500SR Tablet
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.

Drug Warnings

Renulaz 500SR Tablet 10's should be taken with caution in liver/kidney disease, are pregnant, plan to become pregnant, or are breastfeeding, history of heart disease. Also, grapefruit juice should be avoided while taking Renulaz 500SR Tablet 10's. As a precautionary measure, junk food items from outside and stick to freshly prepared home-cooked meals for a speedy recovery. Do regular exercise to avoid the feeling of heaviness in the abdomen.

Drug-Drug Interactions

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RanolazineEnzalutamide
Critical
RanolazineNevirapine
Critical

Drug-Drug Interactions

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RanolazineEnzalutamide
Critical
How does the drug interact with Renulaz 500SR Tablet:
Taking Enzalutamide may decrease the blood levels of Renulaz 500SR Tablet, which may make Renulaz 500SR Tablet less effective.

How to manage the interaction:
Taking Enzalutamide with Renulaz 500SR Tablet is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. Do not discontinue any medications without a doctor's advice.
RanolazineNevirapine
Critical
How does the drug interact with Renulaz 500SR Tablet:
Co-administration of Nevirapine with Renulaz 500SR Tablet may significantly reduce the blood levels of Renulaz 500SR Tablet. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Nevirapine with Renulaz 500SR Tablet is generally avoided as it can lead to an interaction, they can be taken together if advised by a doctor. However, contact a doctor if you experience any symptoms. Do not stop taking any medications without consulting a doctor.
RanolazinePosaconazole
Critical
How does the drug interact with Renulaz 500SR Tablet:
When Posaconazole is taken with Renulaz 500SR Tablet, may significantly increase the blood levels and effects of Renulaz 500SR Tablet.

How to manage the interaction:
Although there is an interaction between posaconazole and Renulaz 500SR Tablet, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not discontinue any medications without consulting a doctor.
RanolazineCarbamazepine
Critical
How does the drug interact with Renulaz 500SR Tablet:
Taking Renulaz 500SR Tablet with carbamazepine may significantly reduce the blood levels of Renulaz 500SR Tablet, which may make the medication ineffective or less effective.

How to manage the interaction:
Taking Renulaz 500SR Tablet with Carbamazepine together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
RanolazineItraconazole
Critical
How does the drug interact with Renulaz 500SR Tablet:
The blood levels and effects of Renulaz 500SR Tablet may be greatly increased when it is used with Itraconazole.

How to manage the interaction:
Although Renulaz 500SR Tablet and Itraconazole may interact, but if prescribed by a doctor, they can be used together. Consult a doctor if you develop any negative symptoms, including fainting, lightheadedness, dizziness, or rapid heartbeat. Without consulting a doctor, never stop taking any medication.
RanolazineCeritinib
Critical
How does the drug interact with Renulaz 500SR Tablet:
When Ceritinib is taken with Renulaz 500SR Tablet, may significantly increase the blood levels and effects of Renulaz 500SR Tablet.

How to manage the interaction:
Taking Renulaz 500SR Tablet with Ceritinib together can possibly result in an interaction, but it can be taken if a doctor has advised it. In case you experience any side effects like lightheadedness, fainting, dizziness, or fast or pounding heartbeats, consult a doctor. Do not discontinue any medications without consulting a doctor.
RanolazinePentobarbital
Critical
How does the drug interact with Renulaz 500SR Tablet:
When Renulaz 500SR Tablet is taken with Pentobarbital, may significantly reduce the blood levels of Renulaz 500SR Tablet, which may make the medication ineffective or less effective.

How to manage the interaction:
Taking Phenobarbital with Renulaz 500SR Tablet can lead to an interaction, please consult a doctor before taking it. They can be taken together if advised by a doctor. However, contact a doctor if you experience any symptoms. Do not stop taking any medications without consulting a doctor.
RanolazineCisapride
Critical
How does the drug interact with Renulaz 500SR Tablet:
Co-administration of Renulaz 500SR Tablet with Cisapride can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Renulaz 500SR Tablet with Ceritinib together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
RanolazineZiprasidone
Critical
How does the drug interact with Renulaz 500SR Tablet:
Co-administration of Renulaz 500SR Tablet with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Renulaz 500SR Tablet with Ziprasidone together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
RanolazineBexarotene
Critical
How does the drug interact with Renulaz 500SR Tablet:
When Renulaz 500SR Tablet and Bexarotene are taken together, may reduce the blood levels and effects of Renulaz 500SR Tablet.

How to manage the interaction:
Taking Renulaz 500SR Tablet with Bexarotene together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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RANOLAZINE-500MGGrapefruit and Grapefruit Juice
Severe

Drug-Food Interactions

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RANOLAZINE-500MGGrapefruit and Grapefruit Juice
Severe
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Grapefruit juice can increase the levels of Renulaz 500SR Tablet, and high blood levels of food can occasionally cause an irregular heart rhythm that may be serious. Grapefruit and grapefruit juice should be avoided while taking Renulaz 500SR Tablet if possible.

Diet & Lifestyle Advise

  • Maintain a healthy lifestyle by exercising regularly, maintaining weight, and eating a healthy diet.
  • If you suffer from kidney or liver disease, please inform your doctor before taking the Renulaz 500SR Tablet 10's.
  • Alcohol consumption along with Renulaz 500SR Tablet 10's should be avoided as it may cause excessive drowsiness and increase muscle pain.
  • As a precautionary measure, junk food items from outside and stick to freshly prepared home-cooked meals for a speedy recovery.

Habit Forming

No

Therapeutic Class

ANTIANGINALS

Renulaz 500SR Tablet 10's Substitute

Substitutes safety advice
  • Ranozex Tablet 10's

    by Others

    17.91per tablet
  • Ranolaz 500 mg Tablet 15's

    by Others

    18.93per tablet
  • Ranx 500 Tablet 15's

    by Others

    20.61per tablet
  • Rancad Tablet 15's

    by AYUR

    20.73per tablet
  • Ranogard 500 Tablet 10's

    by AYUR

    9.54per tablet

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

The active substance in Renulaz 500SR Tablet 10's is Ranolazine, which reduces sodium ions flow into the heart muscle cells. This interferes with the activity of special channels on the cell surface called 'sodium-dependent calcium channels through which calcium ions normally enter the cells. This reduces the number of calcium ions that enter the cells. Calcium ions normally cause the heart muscle to contract. By reducing the flow of calcium into the cells, Renulaz 500SR Tablet 10's is thought to help the heart to relax, improving blood flow to the heart muscle and relieving the symptoms of angina pectoris.

No, Renulaz 500SR Tablet 10's does not stop acute attacks (sudden attacks) of angina, but Renulaz 500SR Tablet 10's helps prevent a new attack.

No, alcohol should not be taken with Renulaz 500SR Tablet 10's as it may lead to unwanted side effects and increase angina attacks.

Yes, smoking (tobacco) decreases the efficacy of Renulaz 500SR Tablet 10's, especially when taken for angina (chest pain), so it should be avoided while taking Renulaz 500SR Tablet 10's.

Yes, Renulaz 500SR Tablet 10's can cause an upset stomach when taken empty stomach. So, to avoid it, Renulaz 500SR Tablet 10's should be taken with a meal for best results.

Yes, Renulaz 500SR Tablet 10's can cause drowsiness. If you feel excessively sleepy, please consult your doctor for better advice.

Drug-Drug Interactions Checker List

  • CLARITHROMYCIN
  • QUINIDINE
  • DOFETILIDE
  • SOTALOL
  • KETOCONAZOLE
  • ITRACONAZOLE

Disease/Condition Glossary

Angina pectoris: Angina pectoris is discomfort in the chest or chest pain that generally occurs due to coronary artery disease (CAD) when you adequate amount of oxygen and blood is not reaching the heart and its muscles. It can also be due to the blockage of the heart's arteries. It helps prevent any further attack of angina by making the heart work more efficiently, but it does not stop an acute attack of angina pectoris.

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