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  3. Retefast Kit Inj

Retefast Kit Inj, Pack of 1 Injection
Retefast Kit Inj, Pack of 1 Injection
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
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Whats That

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Synonym :

RECOMBINANT TISSUE PLASMINOGEN ACTIVATOR

Composition :

RETEPLASE-18MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Retefast Kit Inj

Retefast Kit Inj is a tissue plasminogen activator indicated for the treatment of acute ST-elevation myocardial infarction (STEMI) to lower the risk of heart failure and death. STEMI is a very serious type of heart attack that occurs due to blockage of the heart’s major arteries.
 
Retefast Kit Inj contains Reteplase, which works by dissolving the blood clot that is blocking the heart blood vessel.
 
In some cases, Retefast Kit Inj may cause side effects such as bleeding, bruising at the injection site, nausea or vomiting. You are advised to talk to your doctor if any of the side effects persist or worsen.
 
Consult your doctor if you are pregnant or breastfeeding. The efficacy and safety of Retefast Kit Inj in children have not been established. Inform your doctor about all the medicines you are taking and your health condition to rule out any unpleasant side effects/interactions.

Uses of Retefast Kit Inj

ST-elevation myocardial infarction (STEMI)

Directions for Use

Retefast Kit Inj will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Retefast Kit Inj is a tissue plasminogen activator indicated for the treatment of acute ST-elevation myocardial infarction (STEMI) to reduce the risk of heart failure and death. Retefast Kit Inj contains Reteplase that works by dissolving the blood clot that is blocking the heart blood vessel. It may also be indicated in the treatment of a recent left bundle branch block (a delay/blockage of electrical impulses to the left side of the heart).

Storage

Store in a cool and dry place away from sunlight
Side effects of Retefast Kit Inj
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.
  • Exercising regularly helps lower the risk of heart problems.
  • Maintain a healthy diet, including vegetables and fruits.
  • Rest well; get enough sleep.
  • Manage stress with yoga and meditation.
  • Limit alcohol and smoking.
  • Regularly exercise and have a balanced diet to maintain a healthy weight.
  • Eat fruits and vegetables to maintain a healthy weight.
  • Include vitamin K-rich foods in your diet for stable anticoagulation control.
  • Limit red and processed meats.
  • Avoid smoking and consumption of alcohol to improve your condition.

Drug Warnings

Retefast Kit Inj should not be used if you are allergic to any of the components in Retefast Kit Inj, in patients with active internal bleeding, recent stroke, recent intracranial or intraspinal surgery or serious head trauma, intracranial neoplasm (brain tumour), arteriovenous malformation, or aneurysm (ballooning and weakened area in an artery), known bleeding diathesis (tendency to bleed or bruise easily), or severe uncontrolled hypertension. Retefast Kit Inj may cause bleeding, hypersensitivity reactions, or cholesterol embolism. Inform your doctor if you have/had recent major surgery, cerebrovascular disease, recent gastrointestinal/genitourinary bleeding, hypertension, subacute bacterial endocarditis, severe hepatic or renal disease, if you are over 75 years or if you are taking any oral anticoagulants. Consult your doctor if you are pregnant or breastfeeding. The safety and effectiveness of Retefast Kit Inj in children have not been established.

Drug-Drug Interactions

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ReteplaseFondaparinux
Severe
ReteplasePrasugrel
Severe

Drug-Drug Interactions

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ReteplaseFondaparinux
Severe
How does the drug interact with Retefast Kit Inj:
Taking Retefast Kit Inj with fondaparinux can increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction between fondaparinux and Retefast Kit Inj, you can take these medicines together if prescribed by your doctor. However, if you experience bleeding, severe back pain, dizziness, black or red stools, severe headache, weakness, and vomiting contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
ReteplasePrasugrel
Severe
How does the drug interact with Retefast Kit Inj:
Taking Prasugrel with Retefast Kit Inj can increase the risk of bleeding.

How to manage the interaction:
Co-administration of Prasugrel with Retefast Kit Inj can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
ReteplaseEnoxaparin
Severe
How does the drug interact with Retefast Kit Inj:
Combining Retefast Kit Inj with Enoxaparin can increase the risk or severity of bleeding.

How to manage the interaction:
Although there is a possible interaction between Enoxaparin and Retefast Kit Inj, you can take these medicines together if prescribed by your doctor. If you notice any symptoms like bleeding, bruising, dizziness, or severe headache, it's important to call a doctor right away. Do not stop using any medications without talking to a doctor.
ReteplaseCangrelor
Severe
How does the drug interact with Retefast Kit Inj:
Co-administration of Cangrelor with Retefast Kit Inj can increase the risk of bleeding.

How to manage the interaction:
Although taking Cangrelor and Retefast Kit Inj together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you notice any of these signs, it's important to contact a doctor right away: difficulty with bleeding, complications, bruising, feeling dizzy or lightheaded, dark or sticky stools, intense headache, weakness, or bleeding or vomiting. Do not stop using any medications without talking to a doctor.
ReteplaseDabigatran etexilate
Severe
How does the drug interact with Retefast Kit Inj:
Taking Dabigatran etexilate with Retefast Kit Inj can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabigatran etexilate with Retefast Kit Inj together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
ReteplaseIbrutinib
Severe
How does the drug interact with Retefast Kit Inj:
Co-administration of Ibrutinib with Retefast Kit Inj can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Ibrutinib with Retefast Kit Inj together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
ReteplaseApixaban
Severe
How does the drug interact with Retefast Kit Inj:
Coadministration of Retefast Kit Inj and Apixaban co-administration may raise the risk of bleeding.

How to manage the interaction:
Even though combining Retefast Kit Inj and Apixaban may cause an interaction, it is still possible to take it if your doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without consulting a doctor, never stop taking any medications.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include vegetables, fruits and whole grains in your diet.
  • Stop smoking.
  • Be physically active every day.
  • Aim for a healthy weight.
  • Limit the consumption of alcohol.
  • Manage stress with meditation.

Habit Forming

No

Therapeutic Class

MISCELLANEOUS

Retefast Kit Inj Substitute

Substitutes safety advice

  • Cathlyse 18 Injection 1's

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  • Mirel Injection 1's

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  • RETELEX KIT INJECTION 2S

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    ₹35653.60per tablet

  • Vascium 18mg Injection

    by Others

    ₹23233.32per tablet

Product Substitutes

Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Aug 20, 2024 | 1:16 PM IST

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Retefast Kit Inj works by dissolving the blood clot that is blocking the heart's blood vessels.

Retefast Kit Inj may increase the risk of bleeding. The sites of bleeding could be internal or external. Talk to your doctor if you have any concerns.

Heparin and Retefast Kit Inj are incompatible. Retefast Kit Inj should not be administered through an intravenous line containing heparin. Please consult your doctor if you have any concerns.

Drug-Drug Interactions Checker List

  • HEPARIN
  • ENOXAPARIN
  • WARFARIN
  • PHENINDIONE
  • ASPIRIN
  • DIPYRIDAMOLE
  • TICLOPIDINE
  • CLOPIDOGREL

Disease/Condition Glossary

ST-elevation myocardial infarction (STEMI): It is a very serious type of heart attack that occurs due to blockage of the heart’s major arteries. Signs and symptoms include dizziness or light-headedness, chest pain or discomfort, shortness of breath, nausea or vomiting, palpitations, anxiety, or sweatiness unexplained by ambient temperature.

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