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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Aug 20, 2024 | 1:16 PM IST

About RETELEX KIT INJECTION 2S

RETELEX KIT INJECTION 2S is a tissue plasminogen activator indicated for the treatment of acute ST-elevation myocardial infarction (STEMI) to lower the risk of heart failure and death. STEMI is a very serious type of heart attack that occurs due to blockage of the heart’s major arteries.
 
RETELEX KIT INJECTION 2S contains Reteplase, which works by dissolving the blood clot that is blocking the heart blood vessel.
 
In some cases, RETELEX KIT INJECTION 2S may cause side effects such as bleeding, bruising at the injection site, nausea or vomiting. You are advised to talk to your doctor if any of the side effects persist or worsen.
 
Consult your doctor if you are pregnant or breastfeeding. The efficacy and safety of RETELEX KIT INJECTION 2S in children have not been established. Inform your doctor about all the medicines you are taking and your health condition to rule out any unpleasant side effects/interactions.

Uses of RETELEX KIT INJECTION 2S

ST-elevation myocardial infarction (STEMI)

Medicinal Benefits

RETELEX KIT INJECTION 2S is a tissue plasminogen activator indicated for the treatment of acute ST-elevation myocardial infarction (STEMI) to reduce the risk of heart failure and death. RETELEX KIT INJECTION 2S contains Reteplase that works by dissolving the blood clot that is blocking the heart blood vessel. It may also be indicated in the treatment of a recent left bundle branch block (a delay/blockage of electrical impulses to the left side of the heart).

Directions for Use

RETELEX KIT INJECTION 2S will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of RETELEX KIT INJECTION 2S

  • Bleeding
  • Bruising at the injection site
  • Vomiting
  • Nausea

Drug Warnings

RETELEX KIT INJECTION 2S should not be used if you are allergic to any of the components in RETELEX KIT INJECTION 2S, in patients with active internal bleeding, recent stroke, recent intracranial or intraspinal surgery or serious head trauma, intracranial neoplasm (brain tumour), arteriovenous malformation, or aneurysm (ballooning and weakened area in an artery), known bleeding diathesis (tendency to bleed or bruise easily), or severe uncontrolled hypertension. RETELEX KIT INJECTION 2S may cause bleeding, hypersensitivity reactions, or cholesterol embolism. Inform your doctor if you have/had recent major surgery, cerebrovascular disease, recent gastrointestinal/genitourinary bleeding, hypertension, subacute bacterial endocarditis, severe hepatic or renal disease, if you are over 75 years or if you are taking any oral anticoagulants. Consult your doctor if you are pregnant or breastfeeding. The safety and effectiveness of RETELEX KIT INJECTION 2S in children have not been established.

Drug Interactions

Drug-Drug Interactions: Inform your doctor if you are taking anti-coagulants (heparin, enoxaparin, warfarin, phenindione, aspirin, dipyridamole, ticlopidine, clopidogrel, vitamin K antagonists).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform your doctor if you have/had cancer, stroke, high blood pressure, active ulcer in the stomach or intestine, portal hypertension, inflammation of the pancreas, bleeding behind or in the eye, or severe liver or kidney problems.

Drug-Drug Interactions Checker List

  • HEPARIN
  • ENOXAPARIN
  • WARFARIN
  • PHENINDIONE
  • ASPIRIN
  • DIPYRIDAMOLE
  • TICLOPIDINE
  • CLOPIDOGREL

Habit Forming

No

Diet & Lifestyle Advise

  • Include vegetables, fruits and whole grains in your diet.
  • Stop smoking.
  • Be physically active every day.
  • Aim for a healthy weight.
  • Limit the consumption of alcohol.
  • Manage stress with meditation.

Disease/Condition Glossary

ST-elevation myocardial infarction (STEMI): It is a very serious type of heart attack that occurs due to blockage of the heart’s major arteries. Signs and symptoms include dizziness or light-headedness, chest pain or discomfort, shortness of breath, nausea or vomiting, palpitations, anxiety, or sweatiness unexplained by ambient temperature.

About RETELEX KIT INJECTION 2S

RETELEX KIT INJECTION 2S is a tissue plasminogen activator indicated for the treatment of acute ST-elevation myocardial infarction (STEMI) to lower the risk of heart failure and death. STEMI is a very serious type of heart attack that occurs due to blockage of the heart’s major arteries.
 
RETELEX KIT INJECTION 2S contains Reteplase, which works by dissolving the blood clot that is blocking the heart blood vessel.
 
In some cases, RETELEX KIT INJECTION 2S may cause side effects such as bleeding, bruising at the injection site, nausea or vomiting. You are advised to talk to your doctor if any of the side effects persist or worsen.
 
Consult your doctor if you are pregnant or breastfeeding. The efficacy and safety of RETELEX KIT INJECTION 2S in children have not been established. Inform your doctor about all the medicines you are taking and your health condition to rule out any unpleasant side effects/interactions.

Non returnable*
COD available

Online payment accepted

Prescription drug

Whats That

tooltip
Non returnable*
COD available

Online payment accepted

Synonym

RECOMBINANT TISSUE PLASMINOGEN ACTIVATOR

Composition

RETEPLASE-18MG

Manufacturer/Marketer

Abbott India Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

Uses of RETELEX KIT INJECTION 2S

ST-elevation myocardial infarction (STEMI)

Medicinal Benefits

RETELEX KIT INJECTION 2S is a tissue plasminogen activator indicated for the treatment of acute ST-elevation myocardial infarction (STEMI) to reduce the risk of heart failure and death. RETELEX KIT INJECTION 2S contains Reteplase that works by dissolving the blood clot that is blocking the heart blood vessel. It may also be indicated in the treatment of a recent left bundle branch block (a delay/blockage of electrical impulses to the left side of the heart).

Side Effects of RETELEX KIT INJECTION 2S

  • Bleeding
  • Bruising at the injection site
  • Vomiting
  • Nausea

Directions for Use

RETELEX KIT INJECTION 2S will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

RETELEX KIT INJECTION 2S should not be used if you are allergic to any of the components in RETELEX KIT INJECTION 2S, in patients with active internal bleeding, recent stroke, recent intracranial or intraspinal surgery or serious head trauma, intracranial neoplasm (brain tumour), arteriovenous malformation, or aneurysm (ballooning and weakened area in an artery), known bleeding diathesis (tendency to bleed or bruise easily), or severe uncontrolled hypertension. RETELEX KIT INJECTION 2S may cause bleeding, hypersensitivity reactions, or cholesterol embolism. Inform your doctor if you have/had recent major surgery, cerebrovascular disease, recent gastrointestinal/genitourinary bleeding, hypertension, subacute bacterial endocarditis, severe hepatic or renal disease, if you are over 75 years or if you are taking any oral anticoagulants. Consult your doctor if you are pregnant or breastfeeding. The safety and effectiveness of RETELEX KIT INJECTION 2S in children have not been established.

Therapeutic Class

MISCELLANEOUS

Drug-Drug Interactions Checker List

  • HEPARIN
  • ENOXAPARIN
  • WARFARIN
  • PHENINDIONE
  • ASPIRIN
  • DIPYRIDAMOLE
  • TICLOPIDINE
  • CLOPIDOGREL

Diet & Lifestyle Advise

  • Include vegetables, fruits and whole grains in your diet.
  • Stop smoking.
  • Be physically active every day.
  • Aim for a healthy weight.
  • Limit the consumption of alcohol.
  • Manage stress with meditation.

Habit Forming

No

Disease/Condition Glossary

ST-elevation myocardial infarction (STEMI): It is a very serious type of heart attack that occurs due to blockage of the heart’s major arteries. Signs and symptoms include dizziness or light-headedness, chest pain or discomfort, shortness of breath, nausea or vomiting, palpitations, anxiety, or sweatiness unexplained by ambient temperature.

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