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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
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Composition :

SIMVASTATIN-20MG

Manufacturer/Marketer :

Wel N Innov Pharmaceuticals

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Simwel-20 Tablet

Simwel-20 Tablet belongs to a group of antilipemic medicines called 'lipid-lowering agents' used to lower the levels of increased cholesterol in the body. Additionally, Simwel-20 Tablet is also used to lower the risk of heart diseases such as heart attack or stroke. High cholesterol levels might cause a build-up of cholesterol on the arteries walls, leading to blockage of blood flow to the heart and other body parts that could cause heart disease, heart attack or stroke.

Simwel-20 Tablet contains 'Simvastatin' that works by blocking HMG-CoA reductase, an enzyme necessary for cholesterol production in the body. Simwel-20 Tablet helps lower the levels of LDL (bad) cholesterol, and triglycerides and raises the levels of HDL (good) cholesterol. Thereby, Simwel-20 Tablet lowers the raised levels of fats, triglycerides and cholesterol, which lowers the risk of heart attack or stroke. 

You are advised to take Simwel-20 Tablet for as long as your doctor has prescribed it for you depending on your medical condition. You may experience certain common side-effects such as headache, stomach pain, constipation, and nausea in some cases. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Do not take Simwel-20 Tablet if you are pregnant, think you may be pregnant or if you are trying for pregnancy. Stop taking Simwel-20 Tablet and consult a doctor immediately if you become pregnant while taking Simwel-20 Tablet . Simwel-20 Tablet may cause dizziness, so be cautious while driving. Avoid consuming alcohol with Simwel-20 Tablet as it could lead to increased dizziness. Simwel-20 Tablet is not recommended for children below 10 years as safety and effectiveness have not been established. Inform your doctor regarding your health condition and the medicines you are taking to rule out any side effects or interactions.

Uses of Simwel-20 Tablet

Hyperlipidaemia (high cholesterol)

Directions for Use

Swallow Simwel-20 Tablet a whole with a glass of water; do not chew, or break it.

Medicinal Benefits

Simwel-20 Tablet contains 'Simvastatin', which belongs to a group of lipid-lowering agents called HMG-CoA reductase inhibitors to lower the increased levels of cholesterol or fat. Simwel-20 Tablet works by blocking the HMG-CoA reductase enzyme, which is necessary for cholesterol production in the body. Simwel-20 Tablet helps lower the levels of LDL (bad) cholesterol and triglycerides and raises the levels of HDL (good) cholesterol. Thereby, Simwel-20 Tablet lowers the blood level of fats and cholesterol and helps prevent a heart attack or stroke. Simwel-20 Tablet as an adjunct to dietary measures is used to reduce the risk of having a heart event due to cardiovascular diseases, the incidence of non-fatal heart attack or stroke, the need for revascularisation procedures (restoration of blood flow to the heart), people with diabetes, pre-existing heart disease, and peripheral vascular disease.  

Storage

Keep Simwel-20 Tablet out of reach and sight of children.

Drug Warnings

Do not take Simwel-20 Tablet if you are allergic to any of its contents; if you are taking fusidic acid or have taken it in the past 7 days. Inform your doctor if you are due to have surgery, drink large amounts of alcohol; if you have liver or kidney problems. Do not take Simwel-20 Tablet if you are pregnant, breastfeeding, think you may be pregnant or if you are trying for pregnancy. Stop taking Simwel-20 Tablet and consult a doctor immediately if you become pregnant while taking Simwel-20 Tablet . Simwel-20 Tablet may cause dizziness, so be cautious while driving. Avoid consuming alcohol with Simwel-20 Tablet as it could lead to increased dizziness. Simwel-20 Tablet is not recommended for children below 10 years as safety and effectiveness have not been established.

Diet & Lifestyle Advise

  • Follow a cholesterol-lowering diet.
  • Exercise regularly. It helps in maintaining proper weight and lowers cholesterol.
  • Limit salt and sugar intake.
  • Avoid smoking and alcohol consumption. 
  • Choose healthy fats and cut down on trans-fat.
  • Include omega-3 fatty acids, fibre-rich food, fruits and vegetables.
  • Get active by doing any physical activity such as swimming, brisk walking or jogging. Take the stairs instead of elevators/lifts.

Side Effects of Simwel-20 Tablet

  • Headache
  • Stomach pain
  • Constipation
  • Nausea

Habit Forming

No

Therapeutic Class

ANTILIPEMICS

Author Details

Doctor imageWe provide you with authentic, trustworthy and relevant information

FAQs

Simwel-20 Tablet works by blocking HMG-CoA reductase, an enzyme necessary for the production of cholesterol in the body. Simwel-20 Tablet helps lower the levels of LDL (bad) cholesterol and triglycerides and raises the levels of HDL (good) cholesterol. Thereby, Simwel-20 Tablet lowers the blood level of raised fats and cholesterol and helps prevent a heart attack or stroke.

Do not discontinue Simwel-20 Tablet without consulting your doctor as it could lead to the rise of cholesterol. To treat your condition effectually, continue taking Simwel-20 Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Simwel-20 Tablet .

Constipation could be a side-effect of Simwel-20 Tablet . Drink plenty of fluids and eat fibre-rich food if you experience constipation. Consult your doctor if you have severe constipation.

Simwel-20 Tablet can be taken by diabetes patients if prescribed by the doctor. Your doctor will monitor your condition closely if you have diabetes. Regular monitoring of blood sugar levels is advised.

Simwel-20 Tablet should not be taken with antibiotics such as fusidic acid as it could lead to a serious muscle problem called rhabdomyolysis (the breakdown of muscle tissue). Inform the doctor that you are taking Simwel-20 Tablet if your doctor has prescribed fusidic acid, the doctor may ask you to temporarily stop taking Simwel-20 Tablet to treat your infection. Your doctor will decide when it is safe to restart treatment with Simwel-20 Tablet .

Simwel-20 Tablet might cause muscle problems, particularly when taken at high doses. In rare conditions, Simwel-20 Tablet might cause serious muscle problems such as rhabdomyolysis (muscle tissue breakdown). Consult your doctor immediately if you experience muscle pain, weakness, and tenderness, especially if associated with fever or tiredness.

Drug-Drug Interactions Checker List

  • FUSIDIC ACID
  • ERYTHROMYCIN
  • CLARITHROMYCIN
  • TELITHROMYCIN
  • INDINAVIR
  • SAQUINAVIR
  • RITONAVIR
  • NELFINAVIR
  • ITRACONAZOLE
  • KETOCONAZOLE
  • POSACONAZOLE
  • VORICONAZOLE
  • BOCEPREVIR
  • TELAPREVIR
  • NEFAZODONE
  • GEMFIBROZIL
  • CYCLOSPORINE
  • DANAZOL
  • COBICISTAT

Special Advise

  • Regular blood tests are advised to determine the effect of Simwel-20 Tablet on lipids. 
  • Consult your doctor immediately if you experience muscle pain, weakness, or tenderness, especially if associated with fever or tiredness.
  • Your doctor may recommend blood tests to monitor liver function prior to the start of treatment and during the treatment with Simwel-20 Tablet . Inform your doctor if you notice yellowing of skin or eyes, unusually dark urine, and tiredness.
  • Simwel-20 Tablet might affect test results for liver function and muscle enzyme (creatin-kinase). Inform the person doing the tests that you are taking Simwel-20 Tablet .
  • It is advisable to have complete cholesterol tests (lipid profile test) at least once a year. It will help you to closely monitor your heart health and risk of heart attack and stroke. 

Disease/Condition Glossary

Hyperlipidaemia: Hyperlipidaemia is commonly known as high cholesterol. Cholesterol is a fatty substance that is naturally produced in the liver because every cell uses it. Cholesterol is also found in fatty foods such as cheese, red meat, and eggs. High cholesterol levels might cause a build-up of fat on the arteries' walls, leading to blockage of blood flow to the heart and other body parts that could cause heart disease, heart attack or stroke. Cholesterol is mainly of two types, namely 'bad cholesterol' and 'good cholesterol'. Bad cholesterol comprises low-density lipoprotein (LDL) and triglycerides (TG) which deposit fat in the arteries leading to their blockage. Good cholesterol consists of high-density lipoprotein (HDL), which prevents the deposition of fats. Risk factors of high cholesterol are a high-fat diet, obesity, lack of physical exercise, and smoking. Usually, there are no specific symptoms of raised or high cholesterol levels, so it is advisable to have complete cholesterol tests (lipid profile tests) at least once a year. It will help monitor your heart health and risk of heart attack or stroke. 

Have a query?

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Simwel-20 Tablet as it may cause increased dizziness.

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Pregnancy

Unsafe

Simwel-20 Tablet belongs to pregnancy category X. Do not take Simwel-20 Tablet if you are pregnant, think you may be pregnant or if you are trying for pregnancy. Stop taking Simwel-20 Tablet and consult a doctor immediately if you become pregnant while taking Simwel-20 Tablet .

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Breast Feeding

Unsafe

It is not known if Simwel-20 Tablet passes into breastmilk. Do not take Simwel-20 Tablet if you are breastfeeding.

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Driving

Caution

Usually, Simwel-20 Tablet does not interfere with your ability to drive or usage of machinery. However, Simwel-20 Tablet may cause dizziness in some people. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Simwel-20 Tablet is not recommended for children below 10years as the safety and effectiveness have not been established.

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