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Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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Manufacturer/Marketer :

Arwana Pharmaceuticals

Consume Type :

ORAL

Return Policy :

Not Returnable

About Vomigra 250mg/10mg Tablet

Vomigra 250mg/10mg Tablet belongs to the group of medications called analgesics. It treats migraine headaches. Besides this, it can also be used to reduce pain in rheumatoid arthritis, gout and dysmenorrhea (menstrual pain). Migraine is a condition characterized by intense headaches. Pain is a symptom that occurs due to various underlying conditions.

Vomigra 250mg/10mg Tablet is a combination of two drugs: Naproxen and Domperidone. Naproxen works by blocking the action of the cyclo-oxygenase (COX) enzyme in the body that produces certain chemical substances such as prostaglandins that cause pain and swelling. Domperidone is an antiemetic agent which prevents nausea and vomiting symptoms by blocking certain receptors (like dopamine and serotonin) that stimulate the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain.

Take Vomigra 250mg/10mg Tablet as prescribed by your doctor. You are advised to take Vomigra 250mg/10mg Tablet for as long as your doctor has prescribed it for you based on your medical condition. Common side-effects of Vomigra 250mg/10mg Tablet are dryness of the mouth, abdominal pain, constipation, drowsiness, dizziness, visual disturbances, hearing problems and headache. Consult your doctor if you feel any discomfort.

Before taking the Vomigra 250mg/10mg Tablet, let your doctor know about all your allergic or hypersensitivity reactions to medicines or food. If you are pregnant or breastfeeding, please tell your doctor so that your doctor will weigh the benefits and any potential risks before prescribing it to you. Also, inform the doctor if you have a history of heart rhythm problems or ulcers due to pain killers. Patients with age above 65 years, pre-existing cardiac diseases such as heart failure, hypertension or stroke, gastrointestinal bleeding (due to pain killers), gastric ulcers, respiratory diseases such as asthma, liver diseases, kidney diseases or bleeding disorders should use Vomigra 250mg/10mg Tablet only when prescribed by a doctor.

Uses of Vomigra 250mg/10mg Tablet

Migraine headache, Pain associated with conditions like rheumatoid arthritis, gout and dysmenorrhea (menstrual pain).

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Vomigra 250mg/10mg Tablet is a combination of naproxen and domperidone. Naproxen is an anti-inflammatory (reduce inflammation) and analgesic (reduce pain) agent. It inhibits the synthesis of prostaglandins, which are inflammatory mediators, thereby reducing pain and inflammation. Domperidone acts by enhancing gastric peristalsis (movements) to empty stomach. Easy movement of food through the stomach helps in relieving nausea and vomiting. It blocks the dopamine receptors present at the chemoreceptor trigger zone (responsible for regulating nausea and vomiting).

Storage

Keep Vomigra 250mg/10mg Tablet out of sight and reach of children.

Drug Warnings

Inform your doctor if you are taking any of the anticoagulants (warfarin), other NSAIDs (ibuprofen, ketorolac), corticosteroids (prednisolone), antidepressants (citalopram, fluoxetine, paroxetine, duloxetine, venlafaxine), or any other dietary or herbal supplements. Long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs) (other than aspirin) such as naproxen may increase the risk of heart attack or stroke and stomach ulcers. The risk of developing ulcers is higher if you have a history of ulcers, have bleeding disorders, older in age, alcoholic or have multiple diseases. The risk of having a heart attack increases if you smoke, or you or your family has a history of heart failure, stroke, or hypertension. Call for medical help immediately, if you experience chest pain, shortness of breath, blood in the stool or dark stools, heartburn, or any other abnormal signs.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Vomigra 250mg/10mg Tablet:
Co-administration of Vomigra 250mg/10mg Tablet with Meloxicam can increase the risk or severity of gastric bleeding, ulceration, and rarely, perforation leading to serious blood loss.

How to manage the interaction:
Taking Meloxicam with Vomigra 250mg/10mg Tablet is not advised as it can possibly result in an interaction, it can be taken if your doctor has advised it. You should seek immediate medical attention if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness; lightheadedness; red or black, tarry stools; coughing up or vomiting fresh or dried blood that looks like coffee grounds; severe headache; and weakness.
How does the drug interact with Vomigra 250mg/10mg Tablet:
Taking cidofovir with Vomigra 250mg/10mg Tablet may increase the risk or severity of kidney problems

How to manage the interaction:
Taking Vomigra 250mg/10mg Tablet with Cidofovir is generally avoided as it can possibly result in an interaction. You should seek immediate medical attention if you develop signs and symptoms such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm.
How does the drug interact with Vomigra 250mg/10mg Tablet:
Coadministration of Ketorolac with Vomigra 250mg/10mg Tablet can increase the risk or severity of gastric bleeding and ulceration.

How to manage the interaction:
Taking Ketorolac with Vomigra 250mg/10mg Tablet together is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
DomperidoneMethadone
Severe
How does the drug interact with Vomigra 250mg/10mg Tablet:
Coadministration of Vomigra 250mg/10mg Tablet with Methadone can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Vomigra 250mg/10mg Tablet and Methadone together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneHalofantrine
Severe
How does the drug interact with Vomigra 250mg/10mg Tablet:
Coadministration of Vomigra 250mg/10mg Tablet with Halofantrine can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Vomigra 250mg/10mg Tablet and Halofantrine together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Vomigra 250mg/10mg Tablet:
Coadministration of Vomigra 250mg/10mg Tablet with Ketoconazole can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Vomigra 250mg/10mg Tablet and Ketoconazole together can cause an interaction, it can be taken if a doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Vomigra 250mg/10mg Tablet:
Coadministration of Vomigra 250mg/10mg Tablet with Citalopram can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Vomigra 250mg/10mg Tablet and Citalopram together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneNefazodone
Severe
How does the drug interact with Vomigra 250mg/10mg Tablet:
Coadministration of Vomigra 250mg/10mg Tablet with Nefazodone can increase the blood levels of Vomigra 250mg/10mg Tablet.

How to manage the interaction:
There may be a possibility of interaction between Vomigra 250mg/10mg Tablet and Nefazodone, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.
DomperidoneBepridil
Severe
How does the drug interact with Vomigra 250mg/10mg Tablet:
Co-administration of Domeperidone and Bepridil can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Vomigra 250mg/10mg Tablet and Bepridil together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Vomigra 250mg/10mg Tablet:
Coadministration of Vomigra 250mg/10mg Tablet with Cisapride can increase the blood levels of Vomigra 250mg/10mg Tablet.

How to manage the interaction:
There may be a possibility of interaction between Vomigra 250mg/10mg Tablet and Cisapride, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Drink plenty of fluids to avoid gastrointestinal problems.
  • Avoid triggers that can increase your migraine headache.
  • Take enough rest.
  • Acupuncture, massage and physical therapy may also be helpful.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listen to soothing music.
  • Avoid smoking and alcohol consumption.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.

Side Effects of Vomigra 250mg/10mg Tablet

  • Abdominal pain
  • Constipation
  • Indigestion
  • Flatulence
  • Dry mouth
  • Glossitis (inflammation of the tongue)
  • Diarrhoea
  • Drowsiness
  • Dizziness
  • Headache
  • Vision problems
  • Hearing problems

Habit Forming

No

Therapeutic Class

ANALGESICS

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Naproxen works by inhibiting the cyclo-oxygenase (COX) enzyme in the body, which creates chemical compounds such as prostaglandins, which induce pain and swelling. Domperidone is an antiemetic that blocks certain receptors (such as dopamine and serotonin) that stimulate the brain's vomiting centre (chemoreceptor trigger zone - CTZ).

Vomigra 250mg/10mg Tablet cannot permanently cure migraine. It can provide relief from pain and headache.

Vomigra 250mg/10mg Tablet on prolonged or frequent use can cause liver or kidney problems. Therefore, it should be only used for a duration as prescribed by the doctor.

Arthritis is a chronic condition of joints with pain and inflammation. Vomigra 250mg/10mg Tablet does not cure arthritis but relieves symptoms of arthritis-like joint pain, swelling and stiffness.

Yes, Vomigra 250mg/10mg Tablet may increase the risk of heart problems such as heart attack and stroke, especially when used in high doses or for a prolonged duration. It is advised to inform your doctor if you have any of these conditions or have a history of heart problems or stroke before taking the Vomigra 250mg/10mg Tablet.

Dry mouth may be caused by Domperidone in Vomigra 250mg/10mg Tablet. Chew a sugar-free sweet or sugar-free gum.

Drug-Drug Interactions Checker List

  • WARFARIN
  • KETOROLAC
  • PREDNISOLONE
  • RAMIPRIL
  • AMLODIPINE
  • AMIKACIN
  • ATORVASTATIN
  • CITALOPRAM
  • FLUOXETINE

Special Advise

  • Your doctor may monitor liver function and kidney function if you are taking Vomigra 250mg/10mg Tablet for long-term.
  • Taking meals at the same time every day and sufficient sleep might help in avoiding migraine attacks. You are recommended to avoid loud music, noisy place, extreme temperatures and bright light. Also, avoid consumption of chocolates, cheese, processed food, smoking and alcohol.

Disease/Condition Glossary

Migraine: Migraine is a condition characterized by intense headaches. It also causes nausea, vomiting, sensitivity to light and sound and difficulty speaking. Bright lights, strong smells, certain foods, loud sounds, stress and hormonal changes act as triggers for migraine. These triggers lead to acute attacks. Acute migraine attacks result in throbbing headaches and pain in the eyes, face or neck.

Pain: Pain is a widely used term used to describe unpleasant feelings or discomfort. It ranges from mild to severe. The severity of the pain depends on the underlying condition.

Rheumatoid arthritis: Rheumatoid arthritis is an auto-immune disease (the body's immune system attacks its tissue) which leads to joint pain and damage. Symptoms of rheumatoid arthritis include pain, swelling, stiffness, deformities and loss of joint function.

Gout: Gout is an inflammatory condition in which uric acid deposits and crystallizes in the joints. It is characterized by acute, severe, and recurring pain attacks, especially at night, redness and swelling in the affected joints.

Dysmenorrhea: Dysmenorrhea refers to abdominal cramps/pain and an unpleasant sensory/emotional experience associated with irregular periods. It occurs just before or during menses. Menstrual cramps that cause throbbing pain in the lower belly during periods may vary from mild to severe. Some of the common symptoms of menstrual cramps include an aching pain in your belly (sometimes severe), a feeling of pressure in your belly, pain in your hips, lower back, and inner thighs.

Have a query?

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Alcohol

Caution

It is advised not to take alcohol as Vomigra 250mg/10mg Tablet can cause dizziness or drowsiness.

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Pregnancy

Caution

Vomigra 250mg/10mg Tablet should be used in pregnant women only if clinically needed, and the benefits outweigh the risks.

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Breast Feeding

Caution

Vomigra 250mg/10mg Tablet should be used in breastfeeding mothers only if the benefits outweigh the risks.

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Driving

Unsafe

It is unsafe to drive after taking Vomigra 250mg/10mg Tablet as it impacts your ability to drive or operate machinery.

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Liver

Caution

Limited information was available for the use of Vomigra 250mg/10mg Tablet in patients suffering from liver impairment. Please consult your doctor if you have any concerns regarding using Vomigra 250mg/10mg Tablet in patients with liver impairment. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Limited information was available for the use of Vomigra 250mg/10mg Tablet in patients suffering from kidney impairment. Please consult your doctor if you have any concerns regarding using Vomigra 250mg/10mg Tablet in patients with kidney impairment. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Caution

Vomigra 250mg/10mg Tablet should be used in children below 12 years of age only when prescribed by a child specialist.

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