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Written By Veda Maddala , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
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Whats That

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Synonym :

ROSUVASTATIN+VITAMIN D3

Manufacturer/Marketer :

Zydus Cadila

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Zyrova D3 Forte Tablet

Zyrova D3 Forte Tablet belongs to the class of medicines called 'antilipemic' or cholesterol-lowering agent primarily used to lower raised cholesterol level. This reduces the risk of heart attack and stroke in future. High cholesterol known as hyperlipidaemia or dyslipidaemia occurs when there is an excess of the unhealthy balance of cholesterol in the blood. When the cholesterol level is high in the blood, your arteries get narrowed and clogged, contributing to heart diseases, like stroke and heart attack. Two cholesterol types are found in our body, namely, good cholesterol (high-density lipoprotein) and bad cholesterol (low-density lipoprotein). Good cholesterol is good for our heart and helps in reducing the bad cholesterol from our body. On the other hand, excess bad cholesterol (LDL) leads to the risk of heart diseases like heart attack and stroke.

Zyrova D3 Forte Tablet is a combination of two drugs: Rosuvastatin (statin) and Cholecalciferol (vitamin D3). Rosuvastatin belongs to the class of statins or HMG-CoA reductase inhibitors that work by inhibiting the HMG-CoA reductase enzyme in the body that is essential to make cholesterol. Thereby, it decreases the production of LDL (bad cholesterol) by the liver. Also, it reduces the risk of stroke or heart attack by reducing the excess cholesterol deposition in the major blood vessels of the brain and heart. Cholecalciferol is vitamin D3 that helps in the absorption of calcium by the body and also relieves muscle pain caused by Rosuvastatin.

Take Zyrova D3 Forte Tablet as prescribed. Your doctor will advise you how often you take Zyrova D3 Forte Tablet based on your medical condition. Some people may experience nausea, headache, stomach pain, dizziness, weakness, muscle pain or constipation. Most of these side effects of Zyrova D3 Forte Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.

If you are allergic to Zyrova D3 Forte Tablet or any other medicines, please tell your doctor. Avoid using Zyrova D3 Forte Tablet if you are pregnant or breastfeeding women and consult a doctor before taking Zyrova D3 Forte Tablet . You are advised to take effective birth control measures while taking Zyrova D3 Forte Tablet to avoid pregnancy while taking Zyrova D3 Forte Tablet . Avoid taking Zyrova D3 Forte Tablet if you have liver disease, including abnormal liver enzyme tests. You recommend maintaining a time gap of 2 hours between taking Zyrova D3 Forte Tablet and antacids containing magnesium or aluminium. Taking these medicines together may reduce the absorption of Zyrova D3 Forte Tablet by antacid. If you have thyroid disorder, severe respiratory failure, hypervitaminosis D (high levels of vitamin D in the body), hypercalcemia (high levels of calcium in the blood), electrolyte imbalance, kidney, liver, heart or muscle problems, please consult a doctor before taking Zyrova D3 Forte Tablet .

Uses of Zyrova D3 Forte Tablet

Hyperlipidemia (high cholesterol), Prevention of heart attack and stroke

Directions for Use

Take Zyrova D3 Forte Tablet with or without food as advised by the doctor. Swallow it as a whole with a glass of water. Do not break, crush or chew it.

Medicinal Benefits

Zyrova D3 Forte Tablet is a combination of two drugs, namely: Rosuvastatin and Cholecalciferol primarily used to lower bad cholesterol and triglyceride levels. Rosuvastatin belongs to the class of statins or HMG-CoA reductase inhibitors that work by inhibiting the HMG-CoA reductase enzyme in the body that is essential to make cholesterol. Thereby, it decreases the production of LDL (bad cholesterol) by the liver. Also, it reduces the risk of stroke or heart attack by reducing the excess cholesterol deposition in the major blood vessels of the brain and heart. Cholecalciferol is vitamin D3 that helps in the absorption of calcium by the body and also relieves muscle pain caused by Rosuvastatin.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

If you are allergic to Zyrova D3 Forte Tablet or any other medicines, please tell your doctor. Avoid using Zyrova D3 Forte Tablet if you are pregnant or breastfeeding women and consult a doctor before taking Zyrova D3 Forte Tablet . You are advised to take effective birth control measures while taking Zyrova D3 Forte Tablet to avoid pregnancy while taking Zyrova D3 Forte Tablet . Maintain a low-fat diet along with Zyrova D3 Forte Tablet for effective results. Avoid taking Zyrova D3 Forte Tablet if you have liver disease, including abnormal liver enzyme tests. You recommend maintaining a time gap of 2 hours between taking Zyrova D3 Forte Tablet and antacids containing magnesium or aluminium. Taking these medicines together may reduce the absorption of Zyrova D3 Forte Tablet by antacid. If you have thyroid disorder, severe respiratory failure, hypervitaminosis D (high levels of vitamin D in the body), hypercalcemia (high levels of calcium in the blood), electrolyte imbalance, kidney, liver, heart or muscle problems, please consult a doctor before taking Zyrova D3 Forte Tablet .

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Zyrova D3 Forte Tablet:
Coadministration of colchicine and Zyrova D3 Forte Tablet may increase the risk of conditions that affect your muscles and kidneys.

How to manage the interaction:
Taking Colchicine with Zyrova D3 Forte Tablet may possibly result in an interaction, but they can be taken together if prescribed by your doctor. However, contact your doctor immediately if you experience abdominal discomfort, nausea, vomiting, diarrhea, back pain, weakness, or tingling or numbness in your hands and feet. Do not discontinue any medication without consulting your doctor.
How does the drug interact with Zyrova D3 Forte Tablet:
Coadministration of Nicotinamide with Zyrova D3 Forte Tablet may increase the risk and severity of side effects like rhabdomyolysis (breakdown of skeletal muscle) or kidney damage which can be fatal.

How to manage the interaction:
Taking Nicotinamide with Zyrova D3 Forte Tablet together can result in an interaction, but it can be taken if your doctor has advised it. If you notice any symptoms like unexplained muscle pain, muscle stiffness or tenderness, fever, dark-coloured urine, or weakness, you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Zyrova D3 Forte Tablet:
Co-administration of leflunomide and Zyrova D3 Forte Tablet can increase the risk of developing liver problems.

How to manage the interaction:
Co-administration of Leflunomide and Zyrova D3 Forte Tablet can lead to an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Zyrova D3 Forte Tablet:
Co-administration of Zyrova D3 Forte Tablet and Fenofibrate can increase the blood levels of Zyrova D3 Forte Tablet and can increase the risk of liver damage and rhabdomyolysis(breakdown of skeletal muscle tissue).

How to manage the interaction:
Co-administration of Zyrova D3 Forte Tablet and Fenofibrate can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, dark-colored urine, fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Zyrova D3 Forte Tablet:
Co-administration of Zyrova D3 Forte Tablet and Atazanavir can increase the blood levels of Zyrova D3 Forte Tablet and can increase the risk of liver damage and rhabdomyolysis( breakdown of skeletal muscle tissue).

How to manage the interaction:
Co-administration of Zyrova D3 Forte Tablet and Atazanavir can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, dark-colored urine, fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Zyrova D3 Forte Tablet:
Co-administration of Zyrova D3 Forte Tablet and Darunavir can increase the blood levels of Zyrova D3 Forte Tablet and can increase the risk of liver damage and rhabdomyolysis(breakdown of skeletal muscle tissue).

How to manage the interaction:
Co-administration of Zyrova D3 Forte Tablet and Darunavir can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, dark-colored urine, fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
RosuvastatinSaquinavir
Severe
How does the drug interact with Zyrova D3 Forte Tablet:
Co-administration of Saquinavir and Zyrova D3 Forte Tablet can increase the blood levels of Zyrova D3 Forte Tablet and can increase the risk of developing liver damage and rhabdomyolysis(breakdown of skeletal muscle tissue).

How to manage the interaction:
Co-administration of Saquinavir and Zyrova D3 Forte Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, dark-colored urine, fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
RosuvastatinSimeprevir
Severe
How does the drug interact with Zyrova D3 Forte Tablet:
Co-administration of Simeprevir and Zyrova D3 Forte Tablet can increase the blood levels of Zyrova D3 Forte Tablet and can increase the risk of side effects like liver damage and rhabdomyolysis( breakdown of skeletal muscle tissue).

How to manage the interaction:
Co-administration of Simeprevir and Zyrova D3 Forte Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, dark-colored urine, fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Zyrova D3 Forte Tablet:
Co-administration of ciclosporin with Zyrova D3 Forte Tablet can increase blood levels of Zyrova D3 Forte Tablet. This can increase the risk of developing side effects.

How to manage the interaction:
Co-administration of cyclosporine and Zyrova D3 Forte Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, or dark-colored urine, light colour stools, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Zyrova D3 Forte Tablet:
Co-administration of Gemfibrozil and Zyrova D3 Forte Tablet may increase the risk or severity of side effects like muscle injury.

How to manage the interaction:
Co-administration of Gemfibrozil and Zyrova D3 Forte Tablet can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, or dark-colored urine, consult the doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a low-fat diet. Limit your intake of dairy products made with whole milk and red meat. Prefer skim milk and fat-free or low-fat dairy products.
  • Eat a healthy diet that includes fruits, vegetables, fish, poultry, whole grains, nuts and cut down beverages, and processed and sugary foods.
  • Do regular exercises such as swimming, cycling, walking, or dancing and focus on losing weight as obesity also raises bad cholesterol and lowers good cholesterol.
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

ANTILIPEMICS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Zyrova D3 Forte Tablet contains Rosuvastatin and Cholecalciferol. Rosuvastatin works by inhibiting the HMG-CoA reductase enzyme in the body that is essential to make cholesterol. Thereby, decreases the production of LDL (bad cholesterol) by the liver. Also, it reduces the risk of stroke or heart attack by reducing the excess cholesterol deposition in the major blood vessels of the brain and heart. Cholecalciferol is vitamin D3 that helps in the absorption of calcium by the body and also relieves muscle pain caused by Rosuvastatin.

You are not recommended to take Zyrova D3 Forte Tablet with fusidic acid as co-administration of these two medicines may lead to a severe muscle problem known as rhabdomyolysis (the breakdown of muscle tissue). Therefore, inform your doctor if you have taken fusidic acid in the last 7 days before taking the Zyrova D3 Forte Tablet . You may be advised to stop taking Zyrova D3 Forte Tablet if you need to take fusidic acid. However, please consult a doctor before taking Zyrova D3 Forte Tablet with any other medicines.

Zyrova D3 Forte Tablet should be used with caution in diabetic patients as it may increase blood sugar levels. Regular monitoring of blood sugar levels is recommended in diabetic patients and inform your doctor before taking Zyrova D3 Forte Tablet if you are diabetic.

You are recommended to avoid eating foods rich in fat or cholesterol and caffeine as it may increase side effects.

Yes, Zyrova D3 Forte Tablet may cause rhabdomyolysis (the breakdown of muscle tissue) and may lead to kidney failure in some patients. It is not necessary for everyone taking Zyrova D3 Forte Tablet to experience this adverse effect. However, if you experience unexplained muscle pain, weakness or tenderness, especially along with fever, dark coloured urine or unusual tiredness, please consult your doctor immediately.

No, you are not recommended to stop taking Zyrova D3 Forte Tablet without consulting your doctor as it may worsen the condition and increase the risk of heart attack and stroke. Therefore, take Zyrova D3 Forte Tablet for as long as your doctor has prescribed it, and if you experience any difficulty while taking Zyrova D3 Forte Tablet , please consult your doctor so that the dose may be gradually reduced.

Drug-Drug Interactions Checker List

  • GEMFIBROZIL
  • FENOFIBRATE
  • EZETIMIBE
  • CYCLOSPORINE
  • CLOPIDOGREL
  • WARFARIN
  • FUSIDIC ACID
  • ERYTHROMYCIN
  • DAROLUTAMIDE
  • RITONAVIR
  • LOPINAVIR
  • ATAZANAVIR
  • GLECAPREVIR
  • PIBRENTASVIR
  • PARITAPREVIR
  • VELPATASVIR
  • REGORAFENIB
  • SOFOSBUVIR
  • VOXILAPREVIR
  • OMBITASVIR
  • ELBASVIR
  • DASABUVIR
  • GRAZOPREVIR

Special Advise

  • Regular blood tests are recommended while taking Zyrova D3 Forte Tablet to monitor cholesterol levels in the blood and liver functioning.
  • Regularly monitor blood sugar levels as Zyrova D3 Forte Tablet may increase the risk of developing diabetes, especially in patients who are overweight, have high blood pressure, or have high levels of fats and sugars in the blood.

Disease/Condition Glossary

High cholesterol known as hyperlipidemia or dyslipidemia occurs when there is an excess of the unhealthy balance of cholesterol in the blood. When there is a high level of cholesterol in the blood, your arteries get narrowed and clogged that finally contributing to heart diseases, like stroke and heart attack. Eating high-fat or high-cholesterol-containing food/drinks and genetic factors are the primary causes of high cholesterol. There are two types of cholesterol found in our body: good cholesterol (high-density lipoprotein) and bad cholesterol (low-density lipoprotein). Good cholesterol is good for our heart and helps in reducing the bad cholesterol in our body. On the other hand, excess bad cholesterol (LDL) leads to the risk of heart diseases like heart attack and stroke.

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