Rosuvastatin+cholecalciferol
About
Rosuvastatin+cholecalciferol belongs to the class of medicines called 'antilipemic' or cholesterol-lowering agent primarily used to lower raised cholesterol level. This reduces the risk of heart attack and stroke in future. High cholesterol known as hyperlipidaemia or dyslipidaemia occurs when there is an excess of the unhealthy balance of cholesterol in the blood. When the cholesterol level is high in the blood, your arteries get narrowed and clogged, contributing to heart diseases, like stroke and heart attack. Two cholesterol types are found in our body, namely, good cholesterol (high-density lipoprotein) and bad cholesterol (low-density lipoprotein). Good cholesterol is good for our heart and helps in reducing the bad cholesterol from our body. On the other hand, excess bad cholesterol (LDL) leads to the risk of heart diseases like heart attack and stroke.
Rosuvastatin+cholecalciferol is a combination of two drugs: Rosuvastatin (statin) and Cholecalciferol (vitamin D3). Rosuvastatin belongs to the class of statins or HMG-CoA reductase inhibitors that work by inhibiting the HMG-CoA reductase enzyme in the body that is essential to make cholesterol. Thereby, it decreases the production of LDL (bad cholesterol) by the liver. Also, it reduces the risk of stroke or heart attack by reducing the excess cholesterol deposition in the major blood vessels of the brain and heart. Cholecalciferol is vitamin D3 that helps in the absorption of calcium by the body and also relieves muscle pain caused by Rosuvastatin.
Take Rosuvastatin+cholecalciferol as prescribed. Your doctor will advise you how often you take Rosuvastatin+cholecalciferol based on your medical condition. Some people may experience nausea, headache, stomach pain, dizziness, weakness, muscle pain or constipation. Most of these side effects of Rosuvastatin+cholecalciferol do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.
If you are allergic to Rosuvastatin+cholecalciferol or any other medicines, please tell your doctor. Avoid using Rosuvastatin+cholecalciferol if you are pregnant or breastfeeding women and consult a doctor before taking Rosuvastatin+cholecalciferol. You are advised to take effective birth control measures while taking Rosuvastatin+cholecalciferol to avoid pregnancy while taking Rosuvastatin+cholecalciferol. Avoid taking Rosuvastatin+cholecalciferol if you have liver disease, including abnormal liver enzyme tests. You recommend maintaining a time gap of 2 hours between taking Rosuvastatin+cholecalciferol and antacids containing magnesium or aluminium. Taking these medicines together may reduce the absorption of Rosuvastatin+cholecalciferol by antacid. If you have thyroid disorder, severe respiratory failure, hypervitaminosis D (high levels of vitamin D in the body), hypercalcemia (high levels of calcium in the blood), electrolyte imbalance, kidney, liver, heart or muscle problems, please consult a doctor before taking Rosuvastatin+cholecalciferol.
Uses of Rosuvastatin+cholecalciferol
Medicinal Benefits
Rosuvastatin+cholecalciferol is a combination of two drugs, namely: Rosuvastatin and Cholecalciferol primarily used to lower bad cholesterol and triglyceride levels. Rosuvastatin belongs to the class of statins or HMG-CoA reductase inhibitors that work by inhibiting the HMG-CoA reductase enzyme in the body that is essential to make cholesterol. Thereby, it decreases the production of LDL (bad cholesterol) by the liver. Also, it reduces the risk of stroke or heart attack by reducing the excess cholesterol deposition in the major blood vessels of the brain and heart. Cholecalciferol is vitamin D3 that helps in the absorption of calcium by the body and also relieves muscle pain caused by Rosuvastatin.
Directions for Use
Storage
Side Effects of Rosuvastatin+cholecalciferol
- Nausea
- Headache
- Stomach pain
- Dizziness
- Weakness
- Muscle pain
- Constipation
In-Depth Precautions and Warning
Drug Warnings
If you are allergic to Rosuvastatin+cholecalciferol or any other medicines, please tell your doctor. Avoid using Rosuvastatin+cholecalciferol if you are pregnant or breastfeeding women and consult a doctor before taking Rosuvastatin+cholecalciferol. You are advised to take effective birth control measures while taking Rosuvastatin+cholecalciferol to avoid pregnancy while taking Rosuvastatin+cholecalciferol. Maintain a low-fat diet along with Rosuvastatin+cholecalciferol for effective results. Avoid taking Rosuvastatin+cholecalciferol if you have liver disease, including abnormal liver enzyme tests. You recommend maintaining a time gap of 2 hours between taking Rosuvastatin+cholecalciferol and antacids containing magnesium or aluminium. Taking these medicines together may reduce the absorption of Rosuvastatin+cholecalciferol by antacid. If you have thyroid disorder, severe respiratory failure, hypervitaminosis D (high levels of vitamin D in the body), hypercalcemia (high levels of calcium in the blood), electrolyte imbalance, kidney, liver, heart or muscle problems, please consult a doctor before taking Rosuvastatin+cholecalciferol.
Drug Interactions
Drug-Drug Interaction: Rosuvastatin+cholecalciferol may have interaction with other medicines used to lower bad cholesterol (gemfibrozil, fenofibrate, ezetimibe), immunosuppressant (cyclosporine), blood thinners (clopidogrel, warfarin), antibiotics (fusidic acid, erythromycin), anticancer drugs (regorafenib, darolutamide) and antiviral drugs (sofosbuvir, voxilaprevir, ombitasvir, ritonavir, lopinavir, atazanavir, elbasvir, glecaprevir, pibrentasvir, paritaprevir, dasabuvir, velpatasvir, grazoprevir).
Drug-Food Interaction: Rosuvastatin+cholecalciferol may interact with alcohol. Therefore, avoid alcohol consumption with Rosuvastatin+cholecalciferol as it may increase the risk of liver problems.
Drug-Disease Interaction: If you have thyroid disorder, severe respiratory failure, hypervitaminosis D (high levels of vitamin D in the body), hypercalcemia (high levels of calcium in the blood), electrolyte imbalance, kidney, liver, heart or muscle problems, please consult a doctor before taking Rosuvastatin+cholecalciferol.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeAvoid consumption of alcohol with Rosuvastatin+cholecalciferol as it may increase the risk of liver damage. Please consult a doctor before consuming alcohol with Rosuvastatin+cholecalciferol.
Pregnancy
unsafeRosuvastatin+cholecalciferol is a Category X pregnancy drug and is considered unsafe for pregnant women as it may cause harm to the unborn baby. So, if you are pregnant or planning for pregnancy, please inform your doctor before taking Rosuvastatin+cholecalciferol.
Breast Feeding
unsafeAvoid breastfeeding while taking Rosuvastatin+cholecalciferol as it may be unsafe for the baby. However, please consult a doctor before taking Rosuvastatin+cholecalciferol.
Driving
cautionRosuvastatin+cholecalciferol usually does not affect your ability to drive or operate machinery. However, if you feel dizzy after taking Rosuvastatin+cholecalciferol, avoid driving or operate machinery.
Liver
cautionPlease consult a doctor if you have any Liver diseases/conditions. Rosuvastatin+cholecalciferol is usually not recommended in patients with liver disease.
Kidney
cautionTake Rosuvastatin+cholecalciferol with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required. Rosuvastatin+cholecalciferol is not recommended in patients with severe kidney problems.
Children
cautionRosuvastatin+cholecalciferol is not recommended for children below 6 years of age. However, Rosuvastatin+cholecalciferol should be used with caution in children above 6 years if prescribed by a doctor.
Habit Forming
Diet & Lifestyle Advise
- Maintain a low-fat diet. Limit your intake of dairy products made with whole milk and red meat. Prefer skim milk and fat-free or low-fat dairy products.
- Eat a healthy diet that includes fruits, vegetables, fish, poultry, whole grains, nuts and cut down beverages, and processed and sugary foods.
- Do regular exercises such as swimming, cycling, walking, or dancing and focus on losing weight as obesity also raises bad cholesterol and lowers good cholesterol.
- Avoid smoking and alcohol consumption.
Special Advise
- Regular blood tests are recommended while taking Rosuvastatin+cholecalciferol to monitor cholesterol levels in the blood and liver functioning.
- Regularly monitor blood sugar levels as Rosuvastatin+cholecalciferol may increase the risk of developing diabetes, especially in patients who are overweight, have high blood pressure, or have high levels of fats and sugars in the blood.
Patients Concern
Disease/Condition Glossary
High cholesterol known as hyperlipidemia or dyslipidemia occurs when there is an excess of the unhealthy balance of cholesterol in the blood. When there is a high level of cholesterol in the blood, your arteries get narrowed and clogged that finally contributing to heart diseases, like stroke and heart attack. Eating high-fat or high-cholesterol-containing food/drinks and genetic factors are the primary causes of high cholesterol. There are two types of cholesterol found in our body: good cholesterol (high-density lipoprotein) and bad cholesterol (low-density lipoprotein). Good cholesterol is good for our heart and helps in reducing the bad cholesterol in our body. On the other hand, excess bad cholesterol (LDL) leads to the risk of heart diseases like heart attack and stroke.
FAQs
Rosuvastatin+cholecalciferol contains Rosuvastatin and Cholecalciferol. Rosuvastatin works by inhibiting the HMG-CoA reductase enzyme in the body that is essential to make cholesterol. Thereby, decreases the production of LDL (bad cholesterol) by the liver. Also, it reduces the risk of stroke or heart attack by reducing the excess cholesterol deposition in the major blood vessels of the brain and heart. Cholecalciferol is vitamin D3 that helps in the absorption of calcium by the body and also relieves muscle pain caused by Rosuvastatin.
You are not recommended to take Rosuvastatin+cholecalciferol with fusidic acid as co-administration of these two medicines may lead to a severe muscle problem known as rhabdomyolysis (the breakdown of muscle tissue). Therefore, inform your doctor if you have taken fusidic acid in the last 7 days before taking the Rosuvastatin+cholecalciferol. You may be advised to stop taking Rosuvastatin+cholecalciferol if you need to take fusidic acid. However, please consult a doctor before taking Rosuvastatin+cholecalciferol with any other medicines.
Rosuvastatin+cholecalciferol should be used with caution in diabetic patients as it may increase blood sugar levels. Regular monitoring of blood sugar levels is recommended in diabetic patients and inform your doctor before taking Rosuvastatin+cholecalciferol if you are diabetic.
You are recommended to avoid eating foods rich in fat or cholesterol and caffeine as it may increase side effects.
Yes, Rosuvastatin+cholecalciferol may cause rhabdomyolysis (the breakdown of muscle tissue) and may lead to kidney failure in some patients. It is not necessary for everyone taking Rosuvastatin+cholecalciferol to experience this adverse effect. However, if you experience unexplained muscle pain, weakness or tenderness, especially along with fever, dark coloured urine or unusual tiredness, please consult your doctor immediately.
No, you are not recommended to stop taking Rosuvastatin+cholecalciferol without consulting your doctor as it may worsen the condition and increase the risk of heart attack and stroke. Therefore, take Rosuvastatin+cholecalciferol for as long as your doctor has prescribed it, and if you experience any difficulty while taking Rosuvastatin+cholecalciferol, please consult your doctor so that the dose may be gradually reduced.
