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  3. Bexinib 5mg Tablet 14's

Bexinib 5mg Tablet 14's, Pack of 1 TABLET
Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
COD available

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Whats That

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Composition :

AXITINIB-5MG

Manufacturer/Marketer :

Adley Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Bexinib 5mg Tablet

Bexinib 5mg Tablet is an anti-cancer medicine used in the treatment of renal cell carcinoma. Renal cell carcinoma, also known as kidney cancer, is a disease in which the cancer or malignant cells grow uncontrollably in the kidney and form a tumour.

Bexinib 5mg Tablet contains Axitinib as an active ingredient, which belongs to the class of medicines known as kinase inhibitors. It works by inhibiting the action of an enzyme (tyrosine kinase) and thus stops the abnormal growth of cancer cells.

Bexinib 5mg Tablet may cause certain side effects such as diarrhea, rash, tiredness, decreased appetite, nausea, vomiting, increased blood pressure, muscle cramps, chest pain, weakness, dizziness, hoarseness, and constipation. Inform your doctor if any of these side effects bother you. Bexinib 5mg Tablet should be taken as advised by your doctor.

Avoid taking Bexinib 5mg Tablet if you are allergic to it or any other components of it. Before taking Bexinib 5mg Tablet , inform your doctor if you have/had liver or kidney disease, gastrointestinal disorders, heart problems, thyroid disorders, or blood disorders. This medicine is known to cause embryo-fetal toxicity. Hence, it is not recommended for use in pregnancy and breastfeeding.

Uses of Bexinib 5mg Tablet

Renal Cell Carcinoma.

Directions for Use

Take Bexinib 5mg Tablet as prescribed by the doctor. It can be taken with or without food in a 12-hour interval. Swallow it as a whole with a glass of water. Do not crush, break, or chew the medicine. Avoid taking more than the prescribed dose of medicine.

Medicinal Benefits

Bexinib 5mg Tablet contains Axitinib, which is used in treating advanced renal cell carcinoma after failure of prior systemic therapy. It works by stopping the action of a tyrosine kinase enzyme that causes the multiplication of cancerous cells. This helps stop the abnormal growth of cancer cells and thus reduce the further spread to other parts of the body. It also decreases the blood supply to cancer tumors to slow down the growth of the tumor.  In this way, Bexinib 5mg Tablet stops the body's production, spread and growth of cancerous cells.

Storage

Keep Bexinib 5mg Tablet out of the sight and reach of children.
Side effects of Bexinib 5mg Tablet
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Consume more protein-rich foods and healthy fats like beans, avocados, cheese, nuts and lean meats to minimize appetite.
  • Prefer foods high in fiber to help feel full for a long time.
  • If you have decreased appetite, eat only when you are hungry.
  • Eat several small meals or snacks all day.
  • Try to take only small sips of fluids while eating.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Drug Warnings

To treat your condition effectually, continue taking Bexinib 5mg Tablet for the period that your doctor has prescribed. Avoid taking Bexinib 5mg Tablet if you are allergic to it or any other components present in it. Caution should be exercised if you have/had liver or kidney disease, any planned surgery, heart disease, stroke, blood or bleeding disorders, or gastrointestinal disorders. Inform your doctor if you are pregnant or are planning to become pregnant before starting the treatment as this medicine is known to cause embryo-fetal toxicity. Breastfeeding should be discontinued in nursing mothers during the treatment as it passes into breast milk and may cause a possible risk to the infant. Avoid driving and operating machines, as this medicine may cause visual disturbances. This medicine is not recommended for use in children below 18 years of age as the safety and efficacy are not established. Bexinib 5mg Tablet may cause hypertension, arterial and venous thrombotic events, hemorrhagic events, hypothyroidism, gastrointestinal perforation and fistula, Reversible Posterior Leukoencephalopathy Syndrome (RPLS), elevated liver enzymes in some patients. Hence, inform your doctor about your complete medication and medical history before taking Bexinib 5mg Tablet .

Drug-Drug Interactions

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AxitinibArmodafinil
Severe
AxitinibPrimidone
Severe

Drug-Drug Interactions

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AxitinibArmodafinil
Severe
How does the drug interact with Bexinib 5mg Tablet:
Armodafinil may reduce the blood levels of Bexinib 5mg Tablet, which may reduce the effect of Bexinib 5mg Tablet.

How to manage the interaction:
If you are supposed to take Armodafinil and Bexinib 5mg Tablet together, your doctor may adjust the dose or monitor you more frequently to safely use both medications. If your symptoms worsen or your condition changes, contact your doctor.
AxitinibPrimidone
Severe
How does the drug interact with Bexinib 5mg Tablet:
Coadministration of Bexinib 5mg Tablet with primidone may decrease the blood levels of Bexinib 5mg Tablet, which may make Bexinib 5mg Tablet less effective in treating the condition.

How to manage the interaction:
Although there is an interaction between primidone and Bexinib 5mg Tablet, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AxitinibDabrafenib
Severe
How does the drug interact with Bexinib 5mg Tablet:
When Bexinib 5mg Tablet is taken with Dabrafenib, the amount of Bexinib 5mg Tablet in the blood may decrease which may make Bexinib 5mg Tablet less effective in treating the condition.

How to manage the interaction:
Although there is a possible interaction between Dabrafenib and Bexinib 5mg Tablet, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
AxitinibTroleandomycin
Severe
How does the drug interact with Bexinib 5mg Tablet:
Co-administration of Bexinib 5mg Tablet with troleandomycin may cause Bexinib 5mg Tablet blood levels to rise significantly, leading to an increased risk of side effects.

How to manage the interaction:
Although there is a possible interaction between Bexinib 5mg Tablet and Troleandomycin, you can take these medicines together if prescribed by a doctor. However, if you experience high blood pressure, diarrhea, nausea, vomiting, constipation, decreased appetite, weight loss, rash, itching or peeling of skin on the hands and feet, chest pain or pressure, pain in the arms, back, neck or jaw, swelling, shortness of breath, numbness or weakness on one side of the body, headache, vision changes, seizures, unusual bleeding or bruising, red or black stools, coughing up or vomiting blood or blood clots, and severe stomach or abdominal pain, consult a doctor. Do not stop using any medications without a doctor’s advice.
AxitinibRifabutin
Severe
How does the drug interact with Bexinib 5mg Tablet:
Coadministration of Rifabutin may decrease the blood levels of Bexinib 5mg Tablet.

How to manage the interaction:
Although taking Bexinib 5mg Tablet and Rifabutin together can cause an interaction, it can be taken if a doctor has suggested it. If you experience any unusual side effects, consult a doctor. Do not stop using any medications without a doctor's advice.
AxitinibTelaprevir
Severe
How does the drug interact with Bexinib 5mg Tablet:
Co-administration of Bexinib 5mg Tablet with telaprevir may cause Bexinib 5mg Tablet blood levels to rise significantly, leading to an increased risk of side effects.

How to manage the interaction:
Co-administration of Bexinib 5mg Tablet with Telaprevir can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience high blood pressure, diarrhea, nausea, vomiting, constipation, decreased appetite, weight loss, rash, itching or peeling of skin on the hands and feet, chest pain or pressure, pain in the arms, back, neck or jaw, swelling, shortness of breath, numbness or weakness on one side of the body, headache, vision changes, seizures, unusual bleeding or bruising, red or black stools, coughing up or vomiting blood or blood clots, and severe stomach or abdominal pain, consult a doctor. Do not stop using any medications without a doctor’s advice.
AxitinibRifampicin
Severe
How does the drug interact with Bexinib 5mg Tablet:
Taking Bexinib 5mg Tablet with rifampicin can decrease the blood levels of Bexinib 5mg Tablet, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between Bexinib 5mg Tablet and rifampicin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
AxitinibCeritinib
Severe
How does the drug interact with Bexinib 5mg Tablet:
Co-administration of Bexinib 5mg Tablet with ceritinib may significantly increase the blood levels of Bexinib 5mg Tablet.

How to manage the interaction:
Although there is an interaction between Bexinib 5mg Tablet and ceritinib, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience high blood pressure, loose stools, nausea, vomiting, constipation, decreased hunger, rashes, itching or peeling of skin on the hands and feet, chest pain, pain in the arms, back, neck or jaw, swelling, shortness of breath, numbness or weakness on one side of the body, headache, vision changes, unusual bleeding, red or black stools, coughing up or vomiting blood or blood clots, and severe stomach or abdominal pain. Do not discontinue any medications without consulting a doctor.
AxitinibRitonavir
Severe
How does the drug interact with Bexinib 5mg Tablet:
Taking Bexinib 5mg Tablet with ritonavir may significantly increase the blood levels of Bexinib 5mg Tablet.

How to manage the interaction:
There may be a possibility of interaction between Bexinib 5mg Tablet and Ritonavir, but it can be taken if prescribed by a doctor. However, if you experience chest pain or pressure, pain in the arms, back, neck, or jaw, swelling, shortness of breath, numbness or weakness on one side of the body, headache, vision changes, unusual bleeding or bruising, red or black stools, coughing up or vomiting blood or blood clots, and extreme stomach or abdominal pain, consult a doctor. Do not discontinue any medications without consulting a doctor.
AxitinibBosentan
Severe
How does the drug interact with Bexinib 5mg Tablet:
Taking Bexinib 5mg Tablet with bosentan may significantly reduce the blood levels of Bexinib 5mg Tablet, making the medication less effective in treating the condition.

How to manage the interaction:
Although using Bosentan and Bexinib 5mg Tablet together can result in an interaction, they can be taken together if advised by a doctor. Do not stop taking any medications without consulting a doctor.

Drug-Food Interactions

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AXITINIB-5MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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AXITINIB-5MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consuming grapefruit or grapefruit juice might raise the medication's levels in the blood leading to side effects such as high blood pressure, diarrhea, nausea, vomiting, constipation, decreased appetite, weight loss, and rash, itching or peeling of skin on the hands and feet. Avoid consuming grapefruit or grapefruit juice during treatment with Bexinib 5mg Tablet.

Diet & Lifestyle Advise

  • Physical activity helps strengthen muscles, reduces fatigue, helps in weight loss, and gives strength. Gentle activities like 20-30 minutes of walking or swimming would be helpful.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Getting adequate sleep as resting helps improve your health and mental ability and improves attention.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath, or listening to soothing music.
  • Eat food rich in antioxidants such as berries, spinach, etc.
  • Foods containing fibre help in better digestion. These include beans, peas, lentils, whole grains, nuts, and seeds.
  • Avoid smoking and alcohol consumption.
  • Maintain a healthy weight.

Side Effects of Bexinib 5mg Tablet

  • Nausea
  • Vomiting
  • Diarrhoea
  • Loss of appetite
  • Skin rash
  • Increased blood pressure
  • Cough
  • Tiredness
  • Visual disturbances
  • Chest pain
  • Dizziness
  • Weakness
  • Hoarseness
  • Peeling of the skin.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Bexinib 5mg Tablet Substitute

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Author Details

Lakshmithulasi YarraguntaDoctor badge

Written By

Lakshmithulasi Yarragunta

Pharm-D (PB)

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 8, 2025 | 9:49 AM IST

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Bexinib 5mg Tablet contains Axitinib, which works by stopping the action of a tyrosine kinase enzyme that causes the multiplication of cancerous cells.

Bexinib 5mg Tablet is safe to be taken by a diabetic person. However, take Bexinib 5mg Tablet only after consulting with a doctor, as they may adjust the dosing according to your condition.

Bexinib 5mg Tablet may cause thyroid dysfunction, leading to decreased thyroid hormone levels. This effect causes hypothyroidism. So, notify your doctor if you feel extremely tired, colder than others, sudden weight gain/ weight loss, hair loss, or change in voice while using this medicine.

Drug-Drug Interactions Checker List

  • CLARITHROMYCIN
  • ITRACONAZOLE
  • KETOCONAZOLE
  • RITONAVIR
  • DILTIAZEM
  • CARBAMAZEPINE
  • PHENYTOIN
  • RIFAMPICIN
  • DEXAMETHASONE

Special Advise

  • Your doctor may suggest periodic liver function tests and urine test to monitor the function of the liver and presence of protein in urine due to the use of Bexinib 5mg Tablet .
  • It is advised to use contraceptive pills while using Bexinib 5mg Tablet to prevent pregnancy.
  • Seek medical attention immediately if you have swelling in your lower legs, fast heartbeats, or trouble breathing as it may be a sign of a heart problem.

Disease/Condition Glossary

Renal Cell Carcinoma: Also known as kidney cancer. It is the most common type of cancer seen in adults. This condition occurs when cancer/ malignant cells grow uncontrollably in the kidney and form a tumor. Advanced kidney cancer (metastatic renal cell carcinoma) occurs when the malignant cells spread to other parts of the body. Symptoms include red, orange, or pink-coloured urine due to the presence of blood in the urine.

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