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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Hari Kumar , MBBS
Non returnable*
COD available

Online payment accepted

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Manufacturer/Marketer :

Cipla Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Cipanec 50mg/300mg/300mg Tablet

Cipanec 50mg/300mg/300mg Tablet belongs to a group of antiretroviral medicines indicated for the treatment of HIV-1 infection in adults and children weighing at least 35kgs. HIV (Human Immunodeficiency Virus) is a virus that attacks the immune system and destroys the white blood cells that help in fighting infection, making the individual susceptible to other infections or illnesses.
 
Cipanec 50mg/300mg/300mg Tablet contains Dolutegravir (integrase inhibitor), Lamivudine (nucleoside reverse transcriptase inhibitor), and Tenofovir disoproxil fumarate (nucleotide reverse transcriptase inhibitor). Dolutegravir increases the immune cells that help fight infections in the body and decreases the amount of HIV in the blood. Lamivudine and Tenofovir disoproxil fumarate work by interfering with the working of nucleotide and nucleoside reverse transcriptase enzymes which are necessary for the reproduction of the virus. Together, Cipanec 50mg/300mg/300mg Tablet helps in treating HIV infection.
 
You are advised to take Cipanec 50mg/300mg/300mg Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as fatigue, diarrhoea, headache, pain, rash, depression, fever, cough, and insomnia. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Practise safe sex and other necessary precautions as Cipanec 50mg/300mg/300mg Tablet does not prevent the spread of HIV infection. Consult your doctor if you are pregnant or planning for pregnancy. Avoid breastfeeding while taking Cipanec 50mg/300mg/300mg Tablet. Cipanec 50mg/300mg/300mg Tablet may cause dizziness, so drive with caution. Cipanec 50mg/300mg/300mg Tablet is not recommended for children weighing below 35 kg. Keep your doctor informed about your health condition and the medicines you are taking to prevent any side effects/interactions.

Uses of Cipanec 50mg/300mg/300mg Tablet

HIV infection

Directions for Use

Swallow Cipanec 50mg/300mg/300mg Tablet as a whole with water; do not chew or crush it.

Medicinal Benefits

Cipanec 50mg/300mg/300mg Tablet is a combination of three drugs, namely: Dolutegravir, Lamivudine and Tenofovir disoproxil fumarate. Cipanec 50mg/300mg/300mg Tablet belongs to a group of antiretroviral medicines indicated for the treatment of HIV-1 infection in adults and children weighing at least 35kgs. Dolutegravir is an integrase inhibitor that increases the immune cells that help fight infections in the body and decreases the amount of HIV in the blood. Lamivudine is a nucleoside reverse transcriptase inhibitor, and Tenofovir disoproxil fumarate is a nucleotide reverse transcriptase inhibitor. They work by interfering with the working of nucleotide and nucleoside reverse transcriptase enzymes which are necessary for the reproduction of the virus. Together, Cipanec 50mg/300mg/300mg Tablet helps in treating HIV infection.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Cipanec 50mg/300mg/300mg Tablet if you are allergic to any of its components. Inform your doctor if you have a history of hepatitis B or C infection, bone problems, pancreas disorder, kidney/liver problems, or if you are taking dofetilide (anti-arrhythmic agent). Practise safe sex and other necessary precautions as Cipanec 50mg/300mg/300mg Tablet does not prevent the spread of HIV infection. Consult your doctor if you are pregnant or planning for pregnancy. Avoid breastfeeding while taking Cipanec 50mg/300mg/300mg Tablet. Cipanec 50mg/300mg/300mg Tablet may cause dizziness, so drive with caution. Cipanec 50mg/300mg/300mg Tablet is not recommended for children weighing below 35 kg. Talk to your doctor immediately if you notice any signs or symptoms of infection or inflammation.

Drug-Drug Interactions

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DolutegravirDofetilide
Critical
LamivudineEmtricitabine
Critical

Drug-Drug Interactions

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DolutegravirDofetilide
Critical
How does the drug interact with Cipanec 50mg/300mg/300mg Tablet:
Taking Cipanec 50mg/300mg/300mg Tablet with dofetilide may possibly reduce the blood levels and effects of Cipanec 50mg/300mg/300mg Tablet. This can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although taking Cipanec 50mg/300mg/300mg Tablet with Dofetilide is not recommended, they can be taken together if prescribed by a doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, or irregular heartbeat. Do not stop taking any medications without consulting a doctor.
LamivudineEmtricitabine
Critical
How does the drug interact with Cipanec 50mg/300mg/300mg Tablet:
Combining these two medications may reduce overall effectiveness due to potential antagonistic effects (opposite actions).

How to manage the interaction:
Taking Emtricitabine with Cipanec 50mg/300mg/300mg Tablet is not recommended, but it can be taken if your doctor prescribes it. Contact your doctor if your symptoms do not improve. Do not stop taking any medication without consulting your doctor.
Critical
How does the drug interact with Cipanec 50mg/300mg/300mg Tablet:
Coadministration of Didanosine with Cipanec 50mg/300mg/300mg Tablet can increase the levels and risk of Didanosine side effects.

How to manage the interaction:
Taking Didanosine with Cipanec 50mg/300mg/300mg Tablet is not recommended, please consult your doctor before taking it. It can be taken if your doctor prescribes it. However, if you experience severe headaches, confusion, weakness, trouble walking, muscle pain, or high fever, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Critical
How does the drug interact with Cipanec 50mg/300mg/300mg Tablet:
Combining Cipanec 50mg/300mg/300mg Tablet and Streptozocin can increase the risk of kidney problems.

How to manage the interaction:
Taking Cipanec 50mg/300mg/300mg Tablet with Streptozocin is not recommended, as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without talking to your doctor.
DolutegravirAttapulgite
Severe
How does the drug interact with Cipanec 50mg/300mg/300mg Tablet:
Taking Cipanec 50mg/300mg/300mg Tablet with Attapulgite can reduce the effectiveness of Cipanec 50mg/300mg/300mg Tablet.

How to manage the interaction:
Taking Cipanec 50mg/300mg/300mg Tablet with Attapulgite together can possibly result in an interaction, they can be taken together if prescribed by your doctor. It is recommended to take Cipanec 50mg/300mg/300mg Tablet at least two hours before or six hours after the attapulgite dose. Do not discontinue using any medications without consulting a doctor.
How does the drug interact with Cipanec 50mg/300mg/300mg Tablet:
Phenobarbital may significantly decrease Cipanec 50mg/300mg/300mg Tablet blood levels, making the medicine less effective.

How to manage the interaction:
Although taking Cipanec 50mg/300mg/300mg Tablet and Phenobarbital together can result in an interaction, they can be taken together if prescribed by a doctor. Do not discontinue using any medications without consulting a doctor.
How does the drug interact with Cipanec 50mg/300mg/300mg Tablet:
Taking Cipanec 50mg/300mg/300mg Tablet with magnesium oxide can reduce the effectiveness of Cipanec 50mg/300mg/300mg Tablet.

How to manage the interaction:
Taking Magnesium oxide with Cipanec 50mg/300mg/300mg Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, take Cipanec 50mg/300mg/300mg Tablet at least two hours before or six hours after the magnesium oxide dose. Do not stop using any medications without talking to a doctor.
DolutegravirAluminium hydroxide
Severe
How does the drug interact with Cipanec 50mg/300mg/300mg Tablet:
Taking Cipanec 50mg/300mg/300mg Tablet with aluminium hydroxide can reduce the effectiveness of Cipanec 50mg/300mg/300mg Tablet.

How to manage the interaction:
Although taking Cipanec 50mg/300mg/300mg Tablet and Aluminum hydroxide together can possibly result in an interaction, they can be taken together if prescribed by your doctor. It is recommended to take Cipanec 50mg/300mg/300mg Tablet at least two hours before or six hours after the aluminium hydroxide dose. Do not discontinue using any medications without consulting a doctor.
How does the drug interact with Cipanec 50mg/300mg/300mg Tablet:
Co-administration of Sodium bicarbonate and Cipanec 50mg/300mg/300mg Tablet reduces the levels of Cipanec 50mg/300mg/300mg Tablet, resulting in reduced effectiveness.

How to manage the interaction:
Although taking Cipanec 50mg/300mg/300mg Tablet and Sodium bicarbonate together can result in an interaction, they can be taken together if prescribed by your doctor. However, if you experience symptoms like fever, chills, diarrhea, sore throat, muscle aches, red or inflamed skin, and pain or burning during urination, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
DolutegravirMagnesium lactate
Severe
How does the drug interact with Cipanec 50mg/300mg/300mg Tablet:
Taking Cipanec 50mg/300mg/300mg Tablet with magnesium lactate can reduce the effectiveness of Cipanec 50mg/300mg/300mg Tablet.

How to manage the interaction:
Although taking Cipanec 50mg/300mg/300mg Tablet and Magnesium lactate together can possibly result in an interaction, they can be taken together if prescribed by your doctor. It is advised to take Cipanec 50mg/300mg/300mg Tablet either two hours before or six hours after taking a dose of Magnesium lactate. Do not discontinue using any medications without consulting a doctor.

Drug-Food Interactions

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DOLUTEGRAVIR-50MG+LAMIVUDINE-300MG+TENOFOVIR DISOPROXIL FUMARATE-300MGHerbal products/medicines
Moderate

Drug-Food Interactions

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DOLUTEGRAVIR-50MG+LAMIVUDINE-300MG+TENOFOVIR DISOPROXIL FUMARATE-300MGHerbal products/medicines
Moderate
Common Foods to Avoid:
St. John’S Wort

How to manage the interaction:
Consuming St.John's Wort with Cipanec 50mg/300mg/300mg Tablet can increase the risk of side effects. Avoid consuming St.John's Wort with Cipanec 50mg/300mg/300mg Tablet.

Diet & Lifestyle Advise

  • Practise safe sex by using condoms; it helps in reducing contact with semen and vaginal fluids.
  • Never share personal items with body fluids or blood on them, such as razor blades or toothbrushes.
  • Avoid sharing used needles, other injections or drug equipment.
  • Eat a healthy and balanced diet. Eat vitamin and nutrient-rich food such as vegetables and fruits as it helps to boost the immune system. Opt for lean protein and whole grains.
  • Avoid eating raw meat and eggs. Consume properly boiled and cooked meat, poultry or seafood.
  • Eat bland and low-fat foods, and avoid spicy or oily foods if you experience nausea or vomiting.
  • Try to reduce emotional and physical stress by spending time with family or by doing whatever makes you happy.

Habit Forming

No

Therapeutic Class

ANTIRETROVIRAL AGENTS

Cipanec 50mg/300mg/300mg Tablet Substitute

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Cipanec 50mg/300mg/300mg Tablet contains Dolutegravir, Lamivudine, and Tenofovir disoproxil fumarate. Dolutegravir increases the immune cells that help fight infections in the body and decreases the amount of HIV in the blood. Lamivudine and Tenofovir disoproxil fumarate work by interfering with the working of nucleotide and nucleoside reverse transcriptase enzymes which are necessary for the reproduction of the virus. Together, Cipanec 50mg/300mg/300mg Tablet helps in treating HIV infection.

Do not stop taking Cipanec 50mg/300mg/300mg Tablet without consulting your doctor as it may reduce the effectiveness of anti-HIV therapy. Continue taking Cipanec 50mg/300mg/300mg Tablet for as long as your doctor has prescribed it to you to treat your condition effectually. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Cipanec 50mg/300mg/300mg Tablet.

Cipanec 50mg/300mg/300mg Tablet might cause lactic acidosis (excess of lactic acid in the blood), a rare but severe side effect. Consult a doctor immediately if you experience stomach pain, vomiting, nausea, drowsiness, and deep rapid breathing, as these could be the signs of lactic acidosis.

Cipanec 50mg/300mg/300mg Tablet may cause bone problems such as bone pain, softening or thinning of bone which might lead to bone fractures. A regular bone density test is advised while taking Cipanec 50mg/300mg/300mg Tablet.

Antacids, laxatives, or other medicines containing magnesium, aluminium or buffered medicines (medicines used to neutralise stomach acids) should be taken 2 hours before and 6 hours after taking Cipanec 50mg/300mg/300mg Tablet. Consult your doctor if you have any concerns.

You can take iron or calcium supplements with Cipanec 50mg/300mg/300mg Tablet if you have taken Cipanec 50mg/300mg/300mg Tablet with food. If you haven’t taken Cipanec 50mg/300mg/300mg Tablet with food, take Cipanec 50mg/300mg/300mg Tablet 2 hours before or 6 hours after taking iron or calcium supplements. Consult your doctor if you have any concerns.

Drug-Drug Interactions Checker List

  • DOFETILIDE

Special Advise

  • Get HIV test done for at least every 3 months.
  • Regular kidney and liver function tests, bone mineral density test while taking Cipanec 50mg/300mg/300mg Tablet is advised. 
  • Cipanec 50mg/300mg/300mg Tablet might affect laboratory test results; inform the person doing the tests that you are taking Cipanec 50mg/300mg/300mg Tablet.
  • Regularly get blood and urine tests done while taking Cipanec 50mg/300mg/300mg Tablet.

Disease/Condition Glossary

HIV infection: HIV (Human Immunodeficiency Virus) is a virus that attacks the immune system and destroys the white blood cells that help in fighting infection, making the individual susceptible to other infections or illnesses. People with HIV experience flu-like symptoms such as fever, chills, rash, night sweats, muscle aches, tiredness, and sore throat. These symptoms usually last for days to several weeks. It spreads through body fluids such as semen, vaginal fluid, and blood. If left untreated, this condition can lead to AIDS (Acquired Immunodeficiency Syndrome). It is a life-long condition, and there is no definite cure for it. However, it can be controlled by treating with antiretroviral drugs. 

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