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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Hari Kumar , MBBS

About Viropil Tablet 30's

Viropil Tablet 30's belongs to a group of antiretroviral medicines indicated for the treatment of HIV-1 infection in adults and children weighing at least 35kgs. HIV (Human Immunodeficiency Virus) is a virus that attacks the immune system and destroys the white blood cells that help in fighting infection, making the individual susceptible to other infections or illnesses.
 
Viropil Tablet 30's contains Dolutegravir (integrase inhibitor), Lamivudine (nucleoside reverse transcriptase inhibitor), and Tenofovir disoproxil fumarate (nucleotide reverse transcriptase inhibitor). Dolutegravir increases the immune cells that help fight infections in the body and decreases the amount of HIV in the blood. Lamivudine and Tenofovir disoproxil fumarate work by interfering with the working of nucleotide and nucleoside reverse transcriptase enzymes which are necessary for the reproduction of the virus. Together, Viropil Tablet 30's helps in treating HIV infection.
 
You are advised to take Viropil Tablet 30's for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as fatigue, diarrhoea, headache, pain, rash, depression, fever, cough, and insomnia. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Practise safe sex and other necessary precautions as Viropil Tablet 30's does not prevent the spread of HIV infection. Consult your doctor if you are pregnant or planning for pregnancy. Avoid breastfeeding while taking Viropil Tablet 30's. Viropil Tablet 30's may cause dizziness, so drive with caution. Viropil Tablet 30's is not recommended for children weighing below 35 kg. Keep your doctor informed about your health condition and the medicines you are taking to prevent any side effects/interactions.

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Non returnable*
COD available

Online payment accepted

Consume Type

ORAL

Return Policy

3 Days Returnable

Expires on or after

Apr-24

for this medicine

Uses of Viropil Tablet 30's

HIV infection

Medicinal Benefits

Viropil Tablet 30's is a combination of three drugs, namely: Dolutegravir, Lamivudine and Tenofovir disoproxil fumarate. Viropil Tablet 30's belongs to a group of antiretroviral medicines indicated for the treatment of HIV-1 infection in adults and children weighing at least 35kgs. Dolutegravir is an integrase inhibitor that increases the immune cells that help fight infections in the body and decreases the amount of HIV in the blood. Lamivudine is a nucleoside reverse transcriptase inhibitor, and Tenofovir disoproxil fumarate is a nucleotide reverse transcriptase inhibitor. They work by interfering with the working of nucleotide and nucleoside reverse transcriptase enzymes which are necessary for the reproduction of the virus. Together, Viropil Tablet 30's helps in treating HIV infection.

Side Effects of Viropil Tablet 30's

  • Fatigue
  • Diarrhoea
  • Headache
  • Pain
  • Rash
  • Depression
  • Fever
  • Cough
  • Insomnia 

Directions for Use

Swallow Viropil Tablet 30's as a whole with water; do not chew or crush it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Viropil Tablet 30's if you are allergic to any of its components. Inform your doctor if you have a history of hepatitis B or C infection, bone problems, pancreas disorder, kidney/liver problems, or if you are taking dofetilide (anti-arrhythmic agent). Practise safe sex and other necessary precautions as Viropil Tablet 30's does not prevent the spread of HIV infection. Consult your doctor if you are pregnant or planning for pregnancy. Avoid breastfeeding while taking Viropil Tablet 30's. Viropil Tablet 30's may cause dizziness, so drive with caution. Viropil Tablet 30's is not recommended for children weighing below 35 kg. Talk to your doctor immediately if you notice any signs or symptoms of infection or inflammation.

Therapeutic Class

ANTIRETROVIRAL AGENTS

Drug-Drug Interactions

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DolutegravirDofetilide
Critical
LamivudineEmtricitabine
Critical

Drug-Drug Interactions

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DolutegravirDofetilide
Critical
How does the drug interact with Viropil Tablet 30's:
Taking Viropil Tablet 30's with dofetilide may possibly reduce the blood levels and effects of Viropil Tablet 30's. This can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although taking Viropil Tablet 30's with Dofetilide is not recommended, they can be taken together if prescribed by a doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, or irregular heartbeat. Do not stop taking any medications without consulting a doctor.
LamivudineEmtricitabine
Critical
How does the drug interact with Viropil Tablet 30's:
Combining these two medications may reduce overall effectiveness due to potential antagonistic effects (opposite actions).

How to manage the interaction:
Taking Emtricitabine with Viropil Tablet 30's is not recommended, but it can be taken if your doctor prescribes it. Contact your doctor if your symptoms do not improve. Do not stop taking any medication without consulting your doctor.
Tenofovir disoproxilDidanosine
Critical
How does the drug interact with Viropil Tablet 30's:
Coadministration of Didanosine with Viropil Tablet 30's can increase the levels and risk of Didanosine side effects.

How to manage the interaction:
Taking Didanosine with Viropil Tablet 30's is not recommended, please consult your doctor before taking it. It can be taken if your doctor prescribes it. However, if you experience severe headaches, confusion, weakness, trouble walking, muscle pain, or high fever, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Tenofovir disoproxilStreptozocin
Critical
How does the drug interact with Viropil Tablet 30's:
Combining Viropil Tablet 30's and Streptozocin can increase the risk of kidney problems.

How to manage the interaction:
Taking Viropil Tablet 30's with Streptozocin is not recommended, as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without talking to your doctor.
DolutegravirMagnesium lactate
Severe
How does the drug interact with Viropil Tablet 30's:
Taking Viropil Tablet 30's with magnesium lactate can reduce the effectiveness of Viropil Tablet 30's.

How to manage the interaction:
Although taking Viropil Tablet 30's and Magnesium lactate together can possibly result in an interaction, they can be taken together if prescribed by your doctor. It is advised to take Viropil Tablet 30's either two hours before or six hours after taking a dose of Magnesium lactate. Do not discontinue using any medications without consulting a doctor.
DolutegravirCarbamazepine
Severe
How does the drug interact with Viropil Tablet 30's:
Taking carbamazepine and Viropil Tablet 30's may possibly reduce the blood levels and effects of Viropil Tablet 30's.

How to manage the interaction:
Although taking carbamazepine and Viropil Tablet 30's together can possibly result in an interaction, it can be taken if your doctor has prescribed it. Do not stop using any medications without first talking to your doctor.
DolutegravirCalcium lactate
Severe
How does the drug interact with Viropil Tablet 30's:
Co-administration of Viropil Tablet 30's with Calcium lactate can reduce the effectiveness of Viropil Tablet 30's.

How to manage the interaction:
Although there is an interaction, Calcium lactate can be taken with Viropil Tablet 30's if prescribed by the doctor. However, Viropil Tablet 30's and calcium carbonate should not be taken orally at the same time. Maintain a gap of 2-6 hours between both medicines. Do not discontinue using any medications without consulting a doctor.
DolutegravirFosamprenavir
Severe
How does the drug interact with Viropil Tablet 30's:
Coadministration of Viropil Tablet 30's and fosamprenavir may decrease the blood levels of Viropil Tablet 30's.

How to manage the interaction:
Although taking Viropil Tablet 30's and Fosamprenavir together can possibly result in an interaction, they can be taken together if prescribed by your doctor. Do not discontinue using any medications without consulting a doctor.
DolutegravirPhenytoin
Severe
How does the drug interact with Viropil Tablet 30's:
Taking Viropil Tablet 30's with phenytoin may significantly reduce the blood levels of Viropil Tablet 30's, which may make the medication less effective in treating infections.

How to manage the interaction:
Although taking Viropil Tablet 30's and Phenytoin together can result in an interaction, they can be taken together if prescribed by a doctor. Do not discontinue using any medications without consulting a doctor.
DolutegravirFerric citrate
Severe
How does the drug interact with Viropil Tablet 30's:
Taking Viropil Tablet 30's with ferric citrate can reduce the effectiveness of Viropil Tablet 30's.

How to manage the interaction:
Although taking Viropil Tablet 30's and Ferric citrate together can possibly result in an interaction, they can be taken together if prescribed by your doctor. It is advised to take Viropil Tablet 30's either two hours before or six hours after taking a dose of Ferric citrate. Do not discontinue using any medications without consulting a doctor.

Drug-Food Interactions

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DOLUTEGRAVIR-50MG+LAMIVUDINE-300MG+TENOFOVIR DISOPROXIL FUMARATE-300MGHerbal products/medicines
Moderate

Drug-Food Interactions

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DOLUTEGRAVIR-50MG+LAMIVUDINE-300MG+TENOFOVIR DISOPROXIL FUMARATE-300MGHerbal products/medicines
Moderate
Common Foods to Avoid:
St. John’S Wort

How to manage the interaction:
Consuming St.John's Wort with Viropil Tablet 30's can increase the risk of side effects. Avoid consuming St.John's Wort with Viropil Tablet 30's.

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • DOFETILIDE

Diet & Lifestyle Advise

  • Practise safe sex by using condoms; it helps in reducing contact with semen and vaginal fluids.
  • Never share personal items with body fluids or blood on them, such as razor blades or toothbrushes.
  • Avoid sharing used needles, other injections or drug equipment.
  • Eat a healthy and balanced diet. Eat vitamin and nutrient-rich food such as vegetables and fruits as it helps to boost the immune system. Opt for lean protein and whole grains.
  • Avoid eating raw meat and eggs. Consume properly boiled and cooked meat, poultry or seafood.
  • Eat bland and low-fat foods, and avoid spicy or oily foods if you experience nausea or vomiting.
  • Try to reduce emotional and physical stress by spending time with family or by doing whatever makes you happy.

Habit Forming

No

Special Advise

  • Get HIV test done for at least every 3 months.
  • Regular kidney and liver function tests, bone mineral density test while taking Viropil Tablet 30's is advised. 
  • Viropil Tablet 30's might affect laboratory test results; inform the person doing the tests that you are taking Viropil Tablet 30's.
  • Regularly get blood and urine tests done while taking Viropil Tablet 30's.

Author Details

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Disease/Condition Glossary

HIV infection: HIV (Human Immunodeficiency Virus) is a virus that attacks the immune system and destroys the white blood cells that help in fighting infection, making the individual susceptible to other infections or illnesses. People with HIV experience flu-like symptoms such as fever, chills, rash, night sweats, muscle aches, tiredness, and sore throat. These symptoms usually last for days to several weeks. It spreads through body fluids such as semen, vaginal fluid, and blood. If left untreated, this condition can lead to AIDS (Acquired Immunodeficiency Syndrome). It is a life-long condition, and there is no definite cure for it. However, it can be controlled by treating with antiretroviral drugs. 

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