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  3. Diltra 50 mg/300 mg/300 mg Tablet 30's

Written By Santoshini Reddy G , M Pharmacy
Reviewed By Hari Kumar , MBBS

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Manufacturer/Marketer :

Aurobindo Pharma Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Diltra 50 mg/300 mg/300 mg Tablet 30's

Diltra 50 mg/300 mg/300 mg Tablet 30's belongs to a group of antiretroviral medicines indicated for the treatment of HIV-1 infection in adults and children weighing at least 35kgs. HIV (Human Immunodeficiency Virus) is a virus that attacks the immune system and destroys the white blood cells that help in fighting infection, making the individual susceptible to other infections or illnesses.
 
Diltra 50 mg/300 mg/300 mg Tablet 30's contains Dolutegravir (integrase inhibitor), Lamivudine (nucleoside reverse transcriptase inhibitor), and Tenofovir disoproxil fumarate (nucleotide reverse transcriptase inhibitor). Dolutegravir increases the immune cells that help fight infections in the body and decreases the amount of HIV in the blood. Lamivudine and Tenofovir disoproxil fumarate work by interfering with the working of nucleotide and nucleoside reverse transcriptase enzymes which are necessary for the reproduction of the virus. Together, Diltra 50 mg/300 mg/300 mg Tablet 30's helps in treating HIV infection.
 
You are advised to take Diltra 50 mg/300 mg/300 mg Tablet 30's for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as fatigue, diarrhoea, headache, pain, rash, depression, fever, cough, and insomnia. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Practise safe sex and other necessary precautions as Diltra 50 mg/300 mg/300 mg Tablet 30's does not prevent the spread of HIV infection. Consult your doctor if you are pregnant or planning for pregnancy. Avoid breastfeeding while taking Diltra 50 mg/300 mg/300 mg Tablet 30's. Diltra 50 mg/300 mg/300 mg Tablet 30's may cause dizziness, so drive with caution. Diltra 50 mg/300 mg/300 mg Tablet 30's is not recommended for children weighing below 35 kg. Keep your doctor informed about your health condition and the medicines you are taking to prevent any side effects/interactions.

Uses of Diltra 50 mg/300 mg/300 mg Tablet 30's

HIV infection

Directions for Use

Swallow Diltra 50 mg/300 mg/300 mg Tablet 30's as a whole with water; do not chew or crush it.

Medicinal Benefits

Diltra 50 mg/300 mg/300 mg Tablet 30's is a combination of three drugs, namely: Dolutegravir, Lamivudine and Tenofovir disoproxil fumarate. Diltra 50 mg/300 mg/300 mg Tablet 30's belongs to a group of antiretroviral medicines indicated for the treatment of HIV-1 infection in adults and children weighing at least 35kgs. Dolutegravir is an integrase inhibitor that increases the immune cells that help fight infections in the body and decreases the amount of HIV in the blood. Lamivudine is a nucleoside reverse transcriptase inhibitor, and Tenofovir disoproxil fumarate is a nucleotide reverse transcriptase inhibitor. They work by interfering with the working of nucleotide and nucleoside reverse transcriptase enzymes which are necessary for the reproduction of the virus. Together, Diltra 50 mg/300 mg/300 mg Tablet 30's helps in treating HIV infection.

Storage

Keep Diltra 50 mg/300 mg/300 mg Tablet 30's out of reach and sight of children.

Drug Warnings

Do not take Diltra 50 mg/300 mg/300 mg Tablet 30's if you are allergic to any of its components. Inform your doctor if you have a history of hepatitis B or C infection, bone problems, pancreas disorder, kidney/liver problems, or if you are taking dofetilide (anti-arrhythmic agent). Practise safe sex and other necessary precautions as Diltra 50 mg/300 mg/300 mg Tablet 30's does not prevent the spread of HIV infection. Consult your doctor if you are pregnant or planning for pregnancy. Avoid breastfeeding while taking Diltra 50 mg/300 mg/300 mg Tablet 30's. Diltra 50 mg/300 mg/300 mg Tablet 30's may cause dizziness, so drive with caution. Diltra 50 mg/300 mg/300 mg Tablet 30's is not recommended for children weighing below 35 kg. Talk to your doctor immediately if you notice any signs or symptoms of infection or inflammation.

Drug-Drug Interactions

verifiedApollotooltip
DolutegravirDofetilide
Critical
LamivudineEmtricitabine
Critical

Drug-Food Interactions

verifiedApollotooltip
DOLUTEGRAVIR-50MG+LAMIVUDINE-300MG+TENOFOVIR DISOPROXIL FUMARATE-300MGHerbal products/medicines
Moderate

Diet & Lifestyle Advise

  • Practise safe sex by using condoms; it helps in reducing contact with semen and vaginal fluids.
  • Never share personal items with body fluids or blood on them, such as razor blades or toothbrushes.
  • Avoid sharing used needles, other injections or drug equipment.
  • Eat a healthy and balanced diet. Eat vitamin and nutrient-rich food such as vegetables and fruits as it helps to boost the immune system. Opt for lean protein and whole grains.
  • Avoid eating raw meat and eggs. Consume properly boiled and cooked meat, poultry or seafood.
  • Eat bland and low-fat foods, and avoid spicy or oily foods if you experience nausea or vomiting.
  • Try to reduce emotional and physical stress by spending time with family or by doing whatever makes you happy.

Habit Forming

No

Therapeutic Class

ANTIRETROVIRAL AGENTS

Author Details

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

FAQs

Diltra 50 mg/300 mg/300 mg Tablet 30's contains Dolutegravir, Lamivudine, and Tenofovir disoproxil fumarate. Dolutegravir increases the immune cells that help fight infections in the body and decreases the amount of HIV in the blood. Lamivudine and Tenofovir disoproxil fumarate work by interfering with the working of nucleotide and nucleoside reverse transcriptase enzymes which are necessary for the reproduction of the virus. Together, Diltra 50 mg/300 mg/300 mg Tablet 30's helps in treating HIV infection.

Do not stop taking Diltra 50 mg/300 mg/300 mg Tablet 30's without consulting your doctor as it may reduce the effectiveness of anti-HIV therapy. Continue taking Diltra 50 mg/300 mg/300 mg Tablet 30's for as long as your doctor has prescribed it to you to treat your condition effectually. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Diltra 50 mg/300 mg/300 mg Tablet 30's.

Diltra 50 mg/300 mg/300 mg Tablet 30's might cause lactic acidosis (excess of lactic acid in the blood), a rare but severe side effect. Consult a doctor immediately if you experience stomach pain, vomiting, nausea, drowsiness, and deep rapid breathing, as these could be the signs of lactic acidosis.

Diltra 50 mg/300 mg/300 mg Tablet 30's may cause bone problems such as bone pain, softening or thinning of bone which might lead to bone fractures. A regular bone density test is advised while taking Diltra 50 mg/300 mg/300 mg Tablet 30's.

Antacids, laxatives, or other medicines containing magnesium, aluminium or buffered medicines (medicines used to neutralise stomach acids) should be taken 2 hours before and 6 hours after taking Diltra 50 mg/300 mg/300 mg Tablet 30's. Consult your doctor if you have any concerns.

You can take iron or calcium supplements with Diltra 50 mg/300 mg/300 mg Tablet 30's if you have taken Diltra 50 mg/300 mg/300 mg Tablet 30's with food. If you haven’t taken Diltra 50 mg/300 mg/300 mg Tablet 30's with food, take Diltra 50 mg/300 mg/300 mg Tablet 30's 2 hours before or 6 hours after taking iron or calcium supplements. Consult your doctor if you have any concerns.

Drug-Drug Interactions Checker List

  • DOFETILIDE

Special Advise

  • Get HIV test done for at least every 3 months.
  • Regular kidney and liver function tests, bone mineral density test while taking Diltra 50 mg/300 mg/300 mg Tablet 30's is advised. 
  • Diltra 50 mg/300 mg/300 mg Tablet 30's might affect laboratory test results; inform the person doing the tests that you are taking Diltra 50 mg/300 mg/300 mg Tablet 30's.
  • Regularly get blood and urine tests done while taking Diltra 50 mg/300 mg/300 mg Tablet 30's.

Disease/Condition Glossary

HIV infection: HIV (Human Immunodeficiency Virus) is a virus that attacks the immune system and destroys the white blood cells that help in fighting infection, making the individual susceptible to other infections or illnesses. People with HIV experience flu-like symptoms such as fever, chills, rash, night sweats, muscle aches, tiredness, and sore throat. These symptoms usually last for days to several weeks. It spreads through body fluids such as semen, vaginal fluid, and blood. If left untreated, this condition can lead to AIDS (Acquired Immunodeficiency Syndrome). It is a life-long condition, and there is no definite cure for it. However, it can be controlled by treating with antiretroviral drugs. 

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