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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Hari Kumar , MBBS
Non returnable*
COD available

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Manufacturer/Marketer :

Zunison Healthcare

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Dexa-SR Capsule

Dexa-SR Capsule belongs to a group of medicines called gastrointestinal agents used to treat acidity, heartburn, gastro-oesophageal reflux disease (GERD), Zollinger-Ellison syndrome, nausea, vomiting, dyspepsia (indigestion), and peptic ulcers. The stomach is usually protected from the acid by a mucous layer. In some cases, due to excess acid production, the mucous layer gets eroded, which leads to acidity-related problems.

Dexa-SR Capsule is a combination of two drugs, namely: Dexrabeprazole (proton pump inhibitor) and Domperidone (a dopamine antagonist). Dexrabeprazole works by blocking the action of an enzyme called gastric proton pump, which is responsible for the production of acid. Domperidone works by increasing the movements and contractions of stomach muscle. Together, Dexa-SR Capsule helps in treating acidity related problems.

You are advised to take Dexa-SR Capsule for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side effects such as dry mouth, stomach pain, diarrhoea, headache, and flatulence. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Inform your doctor if you have a history of gastrointestinal bleeding or intestinal obstruction. Consult your doctor before taking Dexa-SR Capsule if you are pregnant or breastfeeding. Dexa-SR Capsule may cause dizziness, so drive only if you are alert. Dexa-SR Capsule is not recommended for children as safety has not been established. Avoid consuming alcohol with Dexa-SR Capsule as it could lead to increased drowsiness and can elevate the production of stomach acid. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Dexa-SR Capsule

Acidity-related problems

Directions for Use

Take Dexa-SR Capsule 1hour prior to food. Swallow Dexa-SR Capsule as a whole with a glass of water; do not chew or crush it.

Medicinal Benefits

Dexa-SR Capsule is a combination of two drugs, namely: Dexrabeprazole and Domperidone. Dexa-SR Capsule is used to treat acidity, heartburn, gastro-oesophageal reflux disease (GERD), Zollinger-Ellison syndrome, nausea, vomiting, dyspepsia (indigestion), epigastric pain, and peptic ulcers. Dexrabeprazole is a proton pump inhibitor that works by blocking the action of an enzyme called gastric proton pump, which is responsible for the production of acid. Domperidone is a dopamine antagonist which works by increasing the movements and contractions of stomach muscles. Together, Dexa-SR Capsule helps in treating acidity-related problems. 

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Dexa-SR Capsule if you are allergic to any of its components. Inform your doctor if you have severe kidney, heart or liver disease, or if you are due to have Chromogranin A blood test; if you have fungal infections, heart problems, HIV infection, blockage in intestines, pituitary gland tumour, low levels of potassium or magnesium in the blood. Talk to your doctor if you experience weight loss, problems with swallowing, stomach pain, indigestion, vomit food or blood, or if you pass black stools while taking Dexa-SR Capsule . Consult your doctor if you are pregnant or breastfeeding. Dexa-SR Capsule may cause dizziness, so drive only if you are alert.

Drug-Drug Interactions

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DomperidoneNefazodone
Severe
DomperidoneToremifene
Severe

Drug-Drug Interactions

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DomperidoneNefazodone
Severe
How does the drug interact with Dexa-SR Capsule:
Coadministration of Dexa-SR Capsule with Nefazodone can increase the blood levels of Dexa-SR Capsule.

How to manage the interaction:
There may be a possibility of interaction between Dexa-SR Capsule and Nefazodone, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.
DomperidoneToremifene
Severe
How does the drug interact with Dexa-SR Capsule:
Coadministration of Dexa-SR Capsule with Toremifene can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Dexa-SR Capsule and Toremifene together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneCitalopram
Severe
How does the drug interact with Dexa-SR Capsule:
Coadministration of Dexa-SR Capsule with Citalopram can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Dexa-SR Capsule and Citalopram together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneKetoconazole
Severe
How does the drug interact with Dexa-SR Capsule:
Coadministration of Dexa-SR Capsule with Ketoconazole can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Dexa-SR Capsule and Ketoconazole together can cause an interaction, it can be taken if a doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneMethadone
Severe
How does the drug interact with Dexa-SR Capsule:
Coadministration of Dexa-SR Capsule with Methadone can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Dexa-SR Capsule and Methadone together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneCisapride
Severe
How does the drug interact with Dexa-SR Capsule:
Coadministration of Dexa-SR Capsule with Cisapride can increase the blood levels of Dexa-SR Capsule.

How to manage the interaction:
There may be a possibility of interaction between Dexa-SR Capsule and Cisapride, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.
DomperidoneHalofantrine
Severe
How does the drug interact with Dexa-SR Capsule:
Coadministration of Dexa-SR Capsule with Halofantrine can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Dexa-SR Capsule and Halofantrine together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneRitonavir
Severe
How does the drug interact with Dexa-SR Capsule:
Coadministration of Dexa-SR Capsule with Ritonavir can increase the blood levels of Dexa-SR Capsule.

How to manage the interaction:
There may be a possibility of interaction between Dexa-SR Capsule and Ritonavir, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.
DomperidoneBepridil
Severe
How does the drug interact with Dexa-SR Capsule:
Co-administration of Domeperidone and Bepridil can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Dexa-SR Capsule and Bepridil together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneClarithromycin
Severe
How does the drug interact with Dexa-SR Capsule:
Coadministration of Dexa-SR Capsule with Clarithromycin can increase the risk of side effects.

How to manage the interaction:
There may be a possibility of interaction between Dexa-SR Capsule and Clarithromycin, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat smaller meals more often.
  • Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.
  • Maintain a healthy weight by regular exercising.
  • Avoid lying down after eating as it causes acid reflux.
  • Avoid tight-fitting clothes as it might increase the pressure on the abdomen leading to acid reflux.
  • Practise relaxation techniques and avoid stress by doing yoga or meditation.
  • Avoid foods such as high-fat food, spicy food, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea and soda. 
  • Avoid sitting continuously as it may trigger acidity. Take a break of 5 minutes every hour by doing brisk walking or stretching.

Habit Forming

No

Therapeutic Class

GASTROINTESTINAL AGENTS

Dexa-SR Capsule Substitute

Substitutes safety advice
  • Dexpraz-DSR Capsule 10's

    by Others

    20.43per tablet
  • Dexlet-D Capsule 10's

    by Others

    11.70per tablet
  • Kyrab D Capsule 10's

    by Others

    10.98per tablet
  • Elrab DX 30mg/10mg Capsule

    by Others

    10.80per tablet
  • Dxzol D 30mg/10mg Capsule SR

    by Others

    8.12per tablet

Author Details

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Dexa-SR Capsule contains Dexrabeprazole and Domperidone. Dexrabeprazole works by blocking the action of an enzyme called gastric proton pump, which is responsible for the production of acid. Domperidone works by increasing the movements and contractions of stomach muscles. Together, Dexa-SR Capsule helps in treating acidity.

Diarrhoea might be a side-effect of Dexa-SR Capsule . Drink enough fluids and eat non-spicy food if you experience diarrhoea. Consult your doctor if you have severe diarrhoea or if you find blood in stools.

Avoid lying down immediately after meals to prevent acid reflux. Raise the head of the bed 10-20cm by putting a pillow so that the head and chest are above the waist. This helps in preventing acid reflux.

Dry mouth could be a side-effect of Dexa-SR Capsule . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help stimulate saliva and thereby prevents drying of the mouth.

Do not take Dexa-SR Capsule for longer durations unless prescribed by the doctor. Consult your doctor if your condition does not improve even after taking Dexa-SR Capsule for 14days.

On long-term treatment, Dexa-SR Capsule might increase the risk of bone fracture in the spine, wrist or hip. Inform your doctor if you have osteoporosis or if you are taking corticosteroids, as they can increase the risk of bone fractures.

Drug-Drug Interactions Checker List

  • WARFARIN
  • ERYTHROMYCIN
  • CLARITHROMYCIN
  • AMPICILLIN
  • KETOCONAZOLE
  • FLUCONAZOLE
  • VORICONAZOLE
  • DIGOXIN
  • CITALOPRAM
  • ESCITALOPRAM

Special Advise

  • Inform your doctor if you are due to have Chromogranin A blood test.
  • On long-term treatment, Dexa-SR Capsule may cause low magnesium levels, vitamin B12 levels and increase the risk of bone fractures; the doctor may advise regular tests for monitoring your condition.

Disease/Condition Glossary

Acidity: The stomach is usually protected from acid by a mucous layer. In some cases, due to excess acid production, the mucous layer gets eroded, which leads to complications like GERD, acidity, peptic ulcers and Zollinger-Ellison syndrome.

Gastroesophageal reflux disease (GERD): It occurs when stomach acid frequently flows back into the food pipe (oesophagus). This backflow (acid reflux) irritates the food pipe and causes heartburn. Symptoms include heartburn, sour or bitter taste in the mouth, and difficulty swallowing.

Peptic ulcers: Peptic ulcers are sores that develop on the lining of the stomach and intestine due to erosion of the protective stomach lining. Symptoms include nausea, changes in appetite, bloody or dark stools, unexplained weight loss, vomiting, and indigestion.

Zollinger-Ellison syndrome: It is characterised by the formation of tumours in the upper part of the small intestine, which leads to excess acid production. Symptoms include bloating, burping, weight loss, loss of appetite, nausea, and vomiting.

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