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Written By Veda Maddala , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
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Composition :

DIGOXIN-0.25MG

Manufacturer/Marketer :

Clover Health Care Pharma

Consume Type :

ORAL

Return Policy :

Not Returnable

About Digover Tablet 10's

Digover Tablet 10's belongs to a group of medicines called cardiac glycosides used to treat irregular heartbeats and manage the symptoms of heart failure. Heart failure is a chronic condition in which the heart is unable to pump blood as effectively as it should. Irregular heartbeat is a condition in which your heart beats irregularly, too fast or too slow.

Digover Tablet 10's contains digoxin, i.e. cardiac glycosides that help to increase the output force of the heart and reduces the rate of heart contractions. Digover Tablet 10's works on the heart muscle directly and increases the force with which heart muscle contracts with each heartbeat. Thereby, it makes heart efficient in pumping blood around the body and slows down the rate at which heartbeats.

Take Digover Tablet 10's as prescribed. Your doctor will recommend you how often you take Digover Tablet 10's based on your medical condition. Some people may experience common side effects like diarrhoea, nausea, vomiting, dizziness, abnormal heartbeat or skin rash. Most of these side effects of Digover Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.

If you are known to be allergic to Digover Tablet 10's or any other medicines, please tell your doctor. Pregnant or breastfeeding women are advised to consult a doctor before taking the tablet. Regular blood tests are recommended by your doctor while taking Digover Tablet 10's to monitor the amount of Digover Tablet 10's in the bloodstream as its toxicity can lead to several forms of heart rhythm disturbances, vomiting, nausea and visual disturbances. If you have beriberi disease caused due to vitamin B1 deficiency, malabsorption syndrome (unable to absorb minerals from food) or any lung or kidney disease, please inform your doctor before taking Digover Tablet 10's so that the dose may be adjusted or an alternate medicine may be prescribed accordingly. Digover Tablet 10's has a very narrow therapeutic index. It means small differences in dose of drugs in the body may lead to life-threatening conditions or serious side effects. This makes its use limited and requires close monitoring by doctors like regular electrocardiogram (ECG). So, try not to self-medicate and suggest Digover Tablet 10's to others.

Uses of Digover Tablet 10's

Irregular heartbeats, Prevention of heart failure

Directions for Use

Tablet: Take it with or without food as advised by the doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.Paediatric solution: Shake the bottle well before use. Check the label for directions and give it with or without food in doses as prescribed by a doctor with the help of a dosing syringe.

Medicinal Benefits

Digover Tablet 10's is a cardiac glycoside that is used to treat heart failure and irregular heartbeats. Digover Tablet 10's increases the force with which heart muscle contracts with each heartbeat and makes heart efficient in pumping blood around the body. Thus, slows down the rate at which heartbeats and makes heart rate normal. Digover Tablet 10's improves heart failure symptoms such as exercise capacity and reduces the number of hospitalizations.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

If you are known to be allergic to Digover Tablet 10's or any other medicines, please tell your doctor. Pregnant or breastfeeding women are advised to consult a doctor before taking the tablet. Avoid intake of alcohol with Digover Tablet 10's as it may increase the risk of drowsiness. Digover Tablet 10's may cause vision problems in some people. Make sure you are not affected before driving. Regular blood tests are recommended by your doctor while taking Digover Tablet 10's to monitor the amount of digoxin in blood as digoxin toxicity can lead to several forms of heart rhythm disturbances, vomiting, nausea and visual disturbances. If you have beriberi disease caused by vitamin B1 deficiency, malabsorption syndrome (unable to absorb minerals from food), thyroid, or any lung or kidney disease, please inform your doctor before taking Digover Tablet 10's so that the dose may be adjusted or an alternate medicine may be prescribed accordingly. Digover Tablet 10's has a narrow therapeutic index which makes its use limited and requires close monitoring as small change in dose or blood concentration may lead to severe adverse effects, and overdose may lead to life-threatening reactions.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Digover Tablet:
Co-administration of Digover Tablet and Ceritinib may slow down the heart rate and increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is a interaction between Digover Tablet and ceritinib, it can be taken together if prescribed by a doctor. However, if you experience fainting, lightheadedness, sudden dizziness, or irregular heartbeat, contact a doctor immediately. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Digover Tablet:
Co-administration of Digover Tablet and Lapatinib may increase the blood levels and effects of Digover Tablet.

How to manage the interaction:
If you are supposed to take Digover Tablet and Lapatinib together, a doctor may adjust the dose or monitor more frequently to safely use both medications. If you experience diarrhea, nausea, loss of appetite, vomiting, visual disturbances (blurred vision; light halos around objects; green or yellow vision), or an abnormally fast or slow or uneven heartbeat, contact a doctor as these may be signs and symptoms of excessive Digover Tablet levels. Do not discontinue the medication without consulting a doctor.
DigoxinSaquinavir
Severe
How does the drug interact with Digover Tablet:
Co-administration of Digover Tablet and Saquinavir may increase the risk of severe irregular heart rhythm.

How to manage the interaction:
If you are supposed to take Digover Tablet and Saquinavir together, a doctor may adjust the dose or monitor more frequently to safely use both medications. However, if you develop lightheadedness, fainting, sudden dizziness, nausea, vomiting, loss of appetite, slow pulse, vision disturbances, or irregular heartbeat during treatment with these medications. Contact a doctor immediately. Do not discontinue the medication without consulting a doctor.
DigoxinTelaprevir
Severe
How does the drug interact with Digover Tablet:
Co-administration of Digover Tablet with Telaprevir may increase the blood levels and effects of Digover Tablet.

How to manage the interaction:
Although taking Telaprevir and Digover Tablet together can evidently cause an interaction, it can be taken if a doctor has suggested it. Contact a doctor if you experience nausea, vomiting, diarrhea, loss of appetite, visual disturbances (blurred vision; light halos around objects; green or yellow vision), or an abnormally fast or slow or uneven heartbeat, as these may be signs and symptoms of excessive Digover Tablet levels. Do not stop using any medications without a doctor's advice.
How does the drug interact with Digover Tablet:
Coadministration of Digover Tablet and Atazanavir may increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Digover Tablet and Atazanavir, you can take these medicines together if prescribed by a doctor. However, if you develop fainting, lightheadedness, sudden dizziness, or irregular heartbeat, contact a doctor immediately. Do not discontinue the medication without consulting a doctor.
DigoxinBretylium tosilate
Severe
How does the drug interact with Digover Tablet:
Co-administration of Digover Tablet and Bretylium tosilate may increase the effect of Digover Tablet.

How to manage the interaction:
Although taking Bretylium tosilate and Digover Tablet together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you start feeling sick, throwing up, having seizures, feeling tired, or noticing your heart beating too fast or too slow, it's best to call a doctor right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Digover Tablet:
Co-administration of Digover Tablet and Famotidine may increase the level or effect of Digover Tablet.

How to manage the interaction:
Although there is a possible interaction between Digover Tablet and Famotidine, you can take these medicines together if prescribed by a doctor. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Digover Tablet:
Co-administration of Sucralfate together with Digover Tablet may decrease the effects of Digover Tablet.

How to manage the interaction:
If you are supposed to take Digover Tablet and Sucralfate together, your doctor may adjust the dose to safely use both medications. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Digover Tablet:
Co-administration of Calcium gluconate with Digover Tablet may affect heart rhythm.

How to manage the interaction:
Although there is an interaction, Calcium gluconate can be taken with Digover Tablet if prescribed by the doctor. Consult the prescriber if you experience symptoms of irregular heartbeat, blurred vision, chest tightness, nausea, and seizures. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Digover Tablet:
Co-administration of Clarithromycin with Digover Tablet may increase the blood levels and effects of Digover Tablet.

How to manage the interaction:
Although there is a possible interaction, Clarithromycin can be taken with Digover Tablet if prescribed by the doctor. Consult the prescriber if you experience signs and symptoms of excessive Digover Tablet levels such as diarrhea, nausea, loss of appetite, vomiting, visual disturbances, and an abnormally fast or slow or uneven heartbeat. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

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DIGOXIN-0.25MGGrapefruit and Grapefruit Juice
Mild

Drug-Food Interactions

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DIGOXIN-0.25MGGrapefruit and Grapefruit Juice
Mild
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking Digover Tablet with Grapefruit and Grapefruit juice may increase the side effects of Digover Tablet. Consuming Grapefruit and grapefruit juice should be avoided while taking Digover Tablet.

Diet & Lifestyle Advise

  • Maintain a low salt diet and minimize eating processed foods as they contain more sodium. Try to replace salt with spices or herbs to add flavour to the food.
  • Do the regular exercise as it helps to lower blood pressure and keeps blood vessels and heart in good condition.
  • Quit smoking as smoking increases blood pressure and heart rate.
  • Eat balanced and healthy diet which includes plenty of vegetables, fruits, low fat or fat free products.

Habit Forming

No

Therapeutic Class

ANTIARRHYTHMICS

Digover Tablet 10's Substitute

Substitutes safety advice
  • Lanoxin Tablet 10's

    by Others

    1.31per tablet
  • Dixin 0.25 mg Tablet 10's

    by Others

    1.28per tablet
  • Digoxin-0.25 Tablet 10's

    by Others

    1.17per tablet
  • Digon 0.25 mg Tablet 10's

    by Others

    1.26per tablet
  • Caxin 0.25mg Tablet

    by Others

    1.27per tablet

Author Details

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Drug-Diseases Interactions

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DIGOXIN-0.25MGOther conduction disorders
Severe
DIGOXIN-0.25MGAbnormalities of heart beat
Severe

Drug-Diseases Interactions

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DIGOXIN-0.25MGOther conduction disorders
Severe
How does the disease interact with Digover Tablet:
In cases like the Wolff-Parkinson-White syndrome, Digover Tablet may improve accessory route conduction.

How to manage the interaction:
Digover Tablet should be used with caution in patients with Wolff-Parkinson-White syndrome (a heart condition that causes rapid heartbeat).
DIGOXIN-0.25MGAbnormalities of heart beat
Severe
How does the disease interact with Digover Tablet:
Digover Tablet prolongs the PR interval by slowing sinoatrial and AV conduction. Digover Tablet therapy can cause severe sinus bradycardia or sinoatrial block in people with preexisting sinus node dysfunction, and it can cause progressive or full heart block in patients with incomplete AV block.

How to manage the interaction:
Digover Tablet may be administered to patients with complete, stable AV block (an electrical signal that controls your heartbeat is partially or completely blocked) who have congestive heart failure, provided the block was not induced by cardiac glycosides.
DIGOXIN-0.25MGDisorders of mineral metabolism
Severe
How does the disease interact with Digover Tablet:
Digover Tablet and calcium have cumulative effects on inotropy. As a result, Digover Tablet toxicity and dangerous arrhythmias are predisposed in patients with hypercalcemia from any source.

How to manage the interaction:
Hypercalcemia (too much calcium in the blood) should be corrected before starting treatment with Digover Tablet, and serum calcium levels should be monitored during therapy.
DIGOXIN-0.25MGDisorders of mineral metabolism
Severe
How does the disease interact with Digover Tablet:
Digover Tablet and calcium have cumulative effects on inotropy. As a result, Digover Tablet toxicity and dangerous arrhythmias are predisposed in patients with hypercalcemia from any source.

How to manage the interaction:
Hypercalcemia (too much calcium in the blood) should be corrected before starting treatment with Digover Tablet, and serum calcium levels should be monitored during therapy.
DIGOXIN-0.25MGOther disorders of fluid, electrolyte and acid-base balance
Severe
How does the disease interact with Digover Tablet:
Digover Tablet makes the myocardium more sensitive when potassium and/or magnesium are depleted. Despite Digover Tablet serum drug concentrations, Digover Tablet toxicity may happen in patients with hypokalemia or hypomagnesemia.

How to manage the interaction:
Digover Tablet should be used with caution in patients with or who are at risk of developing potassium and/or magnesium deficiency, including patients on diuretic therapy; those with primary or secondary aldosteronism (may have low potassium levels), severe or prolonged diarrhoea or vomiting, malnutrition; and renal dialysis patients. Electrolyte imbalances may be corrected before starting the treatment.
DIGOXIN-0.25MGThyrotoxicosis [hyperthyroidism]
Moderate
How does the disease interact with Digover Tablet:
Treatment of the underlying illness is the best way to control heart failure and/or atrial arrhythmias brought on by hypermetabolic or hyperdynamic conditions such hyperthyroidism, hypoxia, or arteriovenous shunt.

How to manage the interaction:
Digover Tablet should be used with caution in patients with hyperthyroidism. Your doctor may adjust the dose secondary to changes in the thyroid condition.

FAQs

It may take several weeks for Digover Tablet 10's to show its effect. You are recommended to continue taking Digover Tablet 10's for as long as your doctor prescribes it and do not stop taking Digover Tablet 10's suddenly as it may worsen your heart problems. However, if you experience any difficulty while taking Digover Tablet 10's, please consult your doctor.

Yes, Digover Tablet 10's may cause diarrhoea as a side effect. However, it is not necessary for everyone taking Digover Tablet 10's to experience this side effect. You are recommended to drink plenty of fluids to avoid dehydration. Signs of dehydration include decreased urination or dark, strong-smelling urine. Also, do not take any other medicines to treat diarrhoea without consulting your doctor. If the condition persists or worsen, please consult your doctor.

Yes, Digover Tablet 10's may cause yellow or blurred vision in some people. Therefore, be cautious before driving or using machinery.

No, you can eat normally. However, a balanced and healthy diet are advised for effective results.

You are not recommended to take more than the prescribed dose of Digover Tablet 10's as it may cause Digover Tablet 10's toxicity resulting in symptoms such as vomiting, nausea, loss of appetite, tiredness, dizziness or visual disturbances (more than usual yellow-green). However, if you experience any of these symptoms while taking Digover Tablet 10's, please consult a doctor immediately.

No, you are not recommended to take amiodarone with Digover Tablet 10's as co-administration of these two medicines may increase the levels of Digover Tablet 10's in the blood resulting in Digover Tablet 10's toxicity. However, please consult a doctor before taking other medicines with Digover Tablet 10's so that the dose may be adjusted appropriately.

You are recommended to avoid taking Digover Tablet 10's if you have severe heart problems, have a history of Stokes-Adams attacks (abrupt, short-lived unconsciousness caused by a sudden change in a heartbeat), obstructive cardiomyopathy (enlargement of the heart muscle) and Wolff-Parkinson-White syndrome (extra electrical pathway causes fast heartbeat).

Drug-Drug Interactions Checker List

  • AMIODARONE
  • QUINIDINE
  • ATAZANAVIR
  • SAQUINAVIR
  • CLARITHROMYCIN
  • ITRACONAZOLE
  • ADENOSINE
  • DOLASETRON
  • ARBUTAMINE
  • CERITINIB
  • LAPATINIB
  • FINGOLIMOD
  • FLIBANSERIN
  • CALCIUM CHLORIDE
  • CALCIUM GLUCEPTATE
  • CALCIUM GLUCONATE

Special Advise

  • Regular blood tests are advised while taking Digover Tablet 10's to monitor digoxin levels in the blood, potassium levels and kidney functioning.
  • Low salt diet and regular exercise are recommended along with Digover Tablet 10's for effective results.
  • Regular electrocardiogram (ECG) should be done to see the effect of Digover Tablet 10's on your heartbeat.

Disease/Condition Glossary

Heart failure: It is a chronic condition in which the heart is unable to pump blood as effectively as it should. Heart failure may occur due to certain conditions like high blood pressure, swelling or damage of heart muscle, faulty heart valves or narrow arteries in the heart. Symptoms of heart failure include shortness of breath, tiredness, fast heartbeat and swollen legs.

Arrhythmia (irregular heartbeat) is a condition in which your heart beats irregularly, too fast or too slow. Symptoms of irregular heartbeat include chest pain, shortness of breath, fast or slow heartbeat. 60 to 100 beats per minute is generally considered as normal heart rate.

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