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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS

About Flaster-20 Tablet 15's

Flaster-20 Tablet 15's belongs to the group of medicines called 'anti-rheumatic agents' used to relieve symptoms of rheumatoid arthritis and psoriatic arthritis. Rheumatoid arthritis is an auto-immune disease (the body's immune system attacks its tissue) which leads to joint pain and damage. Psoriatic arthritis is a kind of inflammatory arthritis which occurs in patients with psoriasis (red patches of skin with silvery scales). 

Flaster-20 Tablet 15's contains 'Leflunomide' an isoxazole immunomodulatory agent which works by blocking the formation of genetic material, i.e. DNA required for survival of replicating (dividing) cells of the immune system. As a result, it suppresses the activated immune system to reduce pain, inflammation and swelling. 

Take Flaster-20 Tablet 15's at the same time every day as prescribed by your doctor. In some cases, Flaster-20 Tablet 15's may cause common side-effects such as diarrhoea, nausea, stomach pain, indigestion, rash, and hair loss. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Do not take Flaster-20 Tablet 15's if you are pregnant or planning for pregnancy as Flaster-20 Tablet 15's may cause serious congenital disabilities. Flaster-20 Tablet 15's should not be taken by breastfeeding mothers as it passes into breast milk. Flaster-20 Tablet 15's may cause dizziness, so drive with caution. Avoid consuming alcohol along with Flaster-20 Tablet 15's as it could lead to increased dizziness and liver damage. Flaster-20 Tablet 15's may make you more susceptible to infections; consult your doctor if you develop any signs of infections such as fever, sore throat, breathlessness, jaundice, unexplained bleeding or bruising.

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Whats That

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Non returnable*
COD available

Online payment accepted

Composition

LEFLUNOMIDE-20MG

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

Uses of Flaster-20 Tablet 15's

Rheumatoid arthritis, Psoriatic arthritis

Medicinal Benefits

Flaster-20 Tablet 15's belongs to the group of medicines called anti-rheumatic agents used to relieve symptoms of rheumatoid arthritis and psoriatic arthritis. Flaster-20 Tablet 15's is a disease-modifying antirheumatic drug (DMARDs) which inhibits an enzyme called dihydroorotate dehydrogenase and has antiproliferative activity (suppresses the cell growth). Thereby, helps in treating inflammation, redness, and swelling.

Side Effects of Flaster-20 Tablet 15's

  • Diarrhoea
  • Nausea
  • Stomach pain
  • Indigestion
  • Rash
  • Hair loss

Directions for Use

Take Flaster-20 Tablet 15's with or without food. Swallow Flaster-20 Tablet 15's as a whole with water; do not crush or chew it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Flaster-20 Tablet 15's if you are allergic to leflunomide, have severe liverkidney problems, low levels of protein in the blood, immune system problems, bone marrow problems, or serious infections. Flaster-20 Tablet 15's is not recommended to be used in pregnant women, lactating mothers and people below 18 years of age. Talk to your doctor before taking Flaster-20 Tablet 15's if you have/had serious infections like interstitial lung disease (inflammation of lungs), tuberculosis (TB), or pneumonia. Flaster-20 Tablet 15's may cause dizziness, so drive with caution. Flaster-20 Tablet 15's may make you more susceptible to infections; notify the doctor if you develop infections, sore throat, breathlessness, jaundice, unexplained bleeding or bruising.

Therapeutic Class

ANTIRHEUMATICS

Drug-Drug Interactions

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LeflunomideFludrocortisone
Severe
LeflunomideNaltrexone
Severe

Drug-Drug Interactions

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LeflunomideFludrocortisone
Severe
How does the drug interact with Flaster-20 Tablet 15's:
Taking Fludrocortisone with Flaster-20 Tablet 15's can increase the risk of side effects.

How to manage the interaction:
Co-administration of Flaster-20 Tablet 15's with Fludrocortisone can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you notice infection, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain, or burning during urination - contact your doctor immediately. Do not stop using any medications without a doctor's advice.
LeflunomideNaltrexone
Severe
How does the drug interact with Flaster-20 Tablet 15's:
Taking Flaster-20 Tablet 15's and Naltrexone can increase the risk or severity of liver problems.

How to manage the interaction:
Although there is an interaction between Flaster-20 Tablet 15's and Naltrexone, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
LeflunomideBupropion
Severe
How does the drug interact with Flaster-20 Tablet 15's:
Flaster-20 Tablet 15's can cause liver issues, and combining it with bupropion, can enhance the risk.

How to manage the interaction:
Co-administration of bupropion along with Flaster-20 Tablet 15's can lead to interaction, it can be taken if recommended by a doctor. If you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, or yellowing of the skin or eyes, contact the doctor right away. Do not discontinue any medications without consulting a doctor.
LeflunomideIdarubicin
Severe
How does the drug interact with Flaster-20 Tablet 15's:
Taking Idarubicin and Flaster-20 Tablet 15's can increase the risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, Idarubicin can be taken with Flaster-20 Tablet 15's, if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medications without a doctor's advice.
LeflunomideKetoconazole
Severe
How does the drug interact with Flaster-20 Tablet 15's:
Coadministration of Ketoconazole and Flaster-20 Tablet 15's may cause liver injury.

How to manage the interaction:
Although taking Ketoconazole and Flaster-20 Tablet 15's together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you have any of the following symptoms: fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, fatigue, lack of appetite, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not discontinue any medication without consulting a doctor.
LeflunomideOlaparib
Severe
How does the drug interact with Flaster-20 Tablet 15's:
Taking Flaster-20 Tablet 15's with olaparib may increase the risk of infections.

How to manage the interaction:
Although there is an interaction between Flaster-20 Tablet 15's and olaparib, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fatigue, dizziness, lightheadedness, unusual bleeding or bruising, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting a doctor.
LeflunomideMeloxicam
Severe
How does the drug interact with Flaster-20 Tablet 15's:
When Meloxicam and Flaster-20 Tablet 15's are taken together, can increase the risk of liver damage.

How to manage the interaction:
There may be a possibility of interaction between Flaster-20 Tablet 15's and Meloxicam, but it can be taken if prescribed by a doctor. However, if you experience symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, exhaustion, nausea, vomiting, dark urine, light stools, and skin or eye yellowing, decreased hunger, consult the doctor. Do not stop using any medications without talking to the doctor.
LeflunomideDanazol
Severe
How does the drug interact with Flaster-20 Tablet 15's:
Combining Flaster-20 Tablet 15's with Danazol may increase the risk of liver problems.

How to manage the interaction:
Although taking Danazol and Flaster-20 Tablet 15's together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-coloured urine, liver damage, or bleeding - make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
LeflunomideFlurbiprofen
Severe
How does the drug interact with Flaster-20 Tablet 15's:
Using Flurbiprofen with Flaster-20 Tablet 15's can increase the risk of liver problems.

How to manage the interaction:
There may be a possibility of interaction between Flurbiprofen and Flaster-20 Tablet 15's, but it can be taken if prescribed by a doctor. If you notice any of these signs, it's important to contact your doctor right away: liver problems, liver disease, unusual liver enzyme levels, fever, chills, joint discomfort, swelling, bruises, skin irritation, itching, loss of appetite, tiredness, feeling sick, throwing up, dark urine, or bleeding. Do not discontinue any medications without first consulting your doctor.
LeflunomideIbrutinib
Severe
How does the drug interact with Flaster-20 Tablet 15's:
Co-administration of Ibrutinib and Flaster-20 Tablet 15's can increase the risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, Ibrutinib can be taken with Flaster-20 Tablet 15's, if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • IBUPROFEN
  • NAPROXEN
  • ACETAMINOPHEN
  • ASPIRIN
  • DULOXETINE
  • PREDNISONE
  • CELECOXIB
  • AZATHIOPRINE
  • MELOXICAM
  • METHOTREXATE
  • ETANERCEPT
  • ADALIMUMAB
  • ABATACEPT
  • INFLIXIMAB
  • HYDROXYCHLOROQUINE

Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Special Advise

Regular blood tests to monitor your liver function after starting Flaster-20 Tablet 15's, and for every 6-8 weeks are advised.

Author Details

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Disease/Condition Glossary

Rheumatoid arthritis: It is an auto-immune disease (where the body's immune system attacks its tissue) which leads to joint pain and damage. Symptoms of rheumatoid arthritis include pain, inflammation of joints, difficulty in moving and swelling. Patients with rheumatoid arthritis have intense joint pain (especially knee joint) with stiffness. 

Psoriatic arthritis: Psoriatic arthritis is an autoimmune disease characterized by inflammation of the skin (psoriasis) and joints (inflammatory arthritis). It mainly affects large joints in the lower extremities, distal joints of toes and fingers, back and pelvis. Symptoms include inflammation of joints, difficulty moving, swelling, patches of red, scaly skin and pain.

Flaster-20 Tablet 15's Substitute

Substitutes safety advice
  • Lefno-20 Tablet 10's

    26.42per tablet
  • Lefra 20 Tablet 10's

    26.37per tablet
  • Rumalef 20 Tablet 30's

    17.90per tablet
  • Cleft 20 Tablet 10's

    21.83per tablet
  • Lefumide-20 Tablet 10's

    24.03per tablet
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