Lefno-20 Tablet 10's
₹264.2*
MRP ₹293.5
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₹249.5*
MRP ₹293.5
15% CB
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Lefno-20 Tablet 10's belongs to the group of medicines called 'anti-rheumatic agents' used to relieve symptoms of rheumatoid arthritis and psoriatic arthritis. Rheumatoid arthritis is an auto-immune disease (the body's immune system attacks its tissue) which leads to joint pain and damage. Psoriatic arthritis is a kind of inflammatory arthritis which occurs in patients with psoriasis (red patches of skin with silvery scales).
Lefno-20 Tablet 10's contains 'Leflunomide' an isoxazole immunomodulatory agent which works by blocking the formation of genetic material, i.e. DNA required for survival of replicating (dividing) cells of the immune system. As a result, it suppresses the activated immune system to reduce pain, inflammation and swelling.
Take Lefno-20 Tablet 10's at the same time every day as prescribed by your doctor. In some cases, Lefno-20 Tablet 10's may cause common side-effects such as diarrhoea, nausea, stomach pain, indigestion, rash, and hair loss. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
Do not take Lefno-20 Tablet 10's if you are pregnant or planning for pregnancy as Lefno-20 Tablet 10's may cause serious congenital disabilities. Lefno-20 Tablet 10's should not be taken by breastfeeding mothers as it passes into breast milk. Lefno-20 Tablet 10's may cause dizziness, so drive with caution. Avoid consuming alcohol along with Lefno-20 Tablet 10's as it could lead to increased dizziness and liver damage. Lefno-20 Tablet 10's may make you more susceptible to infections; consult your doctor if you develop any signs of infections such as fever, sore throat, breathlessness, jaundice, unexplained bleeding or bruising.
Lefno-20 Tablet 10's belongs to the group of medicines called anti-rheumatic agents used to relieve symptoms of rheumatoid arthritis and psoriatic arthritis. Lefno-20 Tablet 10's is a disease-modifying antirheumatic drug (DMARDs) which inhibits an enzyme called dihydroorotate dehydrogenase and has antiproliferative activity (suppresses the cell growth). Thereby, helps in treating inflammation, redness, and swelling.
Do not take Lefno-20 Tablet 10's if you are allergic to leflunomide, have severe liverkidney problems, low levels of protein in the blood, immune system problems, bone marrow problems, or serious infections. Lefno-20 Tablet 10's is not recommended to be used in pregnant women, lactating mothers and people below 18 years of age. Talk to your doctor before taking Lefno-20 Tablet 10's if you have/had serious infections like interstitial lung disease (inflammation of lungs), tuberculosis (TB), or pneumonia. Lefno-20 Tablet 10's may cause dizziness, so drive with caution. Lefno-20 Tablet 10's may make you more susceptible to infections; notify the doctor if you develop infections, sore throat, breathlessness, jaundice, unexplained bleeding or bruising.
Drug-Drug Interactions: Lefno-20 Tablet 10's may interact with pain killers (ibuprofen, naproxen, acetaminophen, aspirin), anti-depressant (duloxetine), corticosteroids (prednisone), drugs used to treat arthritis (celecoxib, azathioprine, etanercept, adalimumab, meloxicam, methotrexate, abatacept, infliximab), and anti-malarial (hydroxychloroquine).
Drug-Food Interactions: Avoid consuming alcohol along with Lefno-20 Tablet 10's as it could lead to liver damage.
Drug-Disease Interactions: Inform your doctor if you have low immunity, pneumonia, tuberculosis (TB), hypertension (high blood pressure), lung toxicity, peripheral neuropathy (nerve damage), liver and kidney dysfunction.
Regular blood tests to monitor your liver function after starting Lefno-20 Tablet 10's, and for every 6-8 weeks are advised.
Rheumatoid arthritis: It is an auto-immune disease (where the body's immune system attacks its tissue) which leads to joint pain and damage. Symptoms of rheumatoid arthritis include pain, inflammation of joints, difficulty in moving and swelling. Patients with rheumatoid arthritis have intense joint pain (especially knee joint) with stiffness.
Psoriatic arthritis: Psoriatic arthritis is an autoimmune disease characterized by inflammation of the skin (psoriasis) and joints (inflammatory arthritis). It mainly affects large joints in the lower extremities, distal joints of toes and fingers, back and pelvis. Symptoms include inflammation of joints, difficulty moving, swelling, patches of red, scaly skin and pain.
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Alcohol
Unsafe
You are recommended to avoid alcohol consumption while taking Lefno-20 Tablet 10's. Alcohol intake, along with Lefno-20 Tablet 10's, may cause liver disease.
Pregnancy
Unsafe
It is not recommended to take Lefno-20 Tablet 10's while you are pregnant. Lefno-20 Tablet 10's may cause serious birth defects.
Breast Feeding
Unsafe
It is not recommended to take Lefno-20 Tablet 10's while you are breastfeeding. Lefno-20 Tablet 10's passes into breast milk.
Driving
Caution
Lefno-20 Tablet 10's may cause dizziness and tiredness; do not drive or operate heavy machinery if you feel dizzy.
Liver
Caution
Please consult your doctor if you have liver impairment before taking Lefno-20 Tablet 10's.
Kidney
Caution
Please consult your doctor if you have kidney impairment before taking Lefno-20 Tablet 10's.
Children
Unsafe
Lefno-20 Tablet 10's is not approved for children under the age of 18 years.
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