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  3. Lofh 5000IU Injection

Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Non returnable*
COD available

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Composition :

HEPARIN-5000IU

Manufacturer/Marketer :

Abbott India Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

About Lofh 5000IU Injection

Lofh 5000IU Injection belongs to a class of drugs called anticoagulants or blood thinners. Lofh 5000IU Injection is primarily used to prevent and treat deep vein thrombosis (blood clots in leg veins), pulmonary embolism (blood clots in the lung), stroke, Transient ischaemic attack (TIA), and heart attacks.  Deep vein thrombosis is a medical condition in which blood clots form in deep veins usually in the legs. Pulmonary embolism is a condition in which a blood clot blocks the arteries in the lungs. A stroke is a condition where a blood clot restricts the flow of blood to your brain, causing brain cells to die and possibly resulting in permanent brain damage or death. Transient ischaemic attack (TIA) is a condition also called 'mini-strokes', these have similar symptoms to a stroke, but the effects usually last less than 24 hours. Heart attack is a condition where a blood clot blocks a blood vessel supplying your heart, starving it of oxygen and causing chest pain and sometimes death.

Blood clots are formed to stop bleeding that occurs due to tissue injury. Though blood clots are useful to stop bleeding, they may be harmful when abnormally formed within blood vessels as they block blood vessels and inhibit blood flow to essential organs such as the brain, heart, or lungs. Lofh 5000IU Injection works by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot) preventing blood clot formation.

Lofh 5000IU Injection will be administered by a healthcare professional; do not self-administer. Some people may experience hemorrhage, thrombocytopenia (low platelets), hypersensitivity reactions, and elevations of liver enzyme (aminotransferase) levels. Most of these side effects of Lofh 5000IU Injection do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Lofh 5000IU Injection or any other medicines, please tell your doctor. It is not known whether Lofh 5000IU Injection harms the baby or passes into breast milk in pregnancy and breastfeeding state. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Lofh 5000IU Injection. Lofh 5000IU Injection is not recommended for children below 2 months of age. If you have diabetes, kidney or liver problems, bleeding problems, or are aged above 60 years, inform your doctor before taking Lofh 5000IU Injection.

Uses of Lofh 5000IU Injection

Prevention of blood clots.

Directions for Use

Lofh 5000IU Injection will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Lofh 5000IU Injection is primarily used to prevent and treat blood clots by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot). Lofh 5000IU Injection also reduces the risk of blood clots during surgeries (like heart surgery). Lofh 5000IU Injection is used as an anticoagulant in blood transfusion and in a dialysis procedure.

Storage

Keep Lofh 5000IU Injection out of the sight and reach of children.

Drug Warnings

Use Lofh 5000IU Injection cautiously in conditions with increased risk of bleeding. Use of name contraindicated in patients with HIT - Heparin-induced thrombosis (the abnormal formation of blood clots inside a blood vessel) and HITT (heparin-induced thrombocytopenia and thrombosis) might occur. Monitoring of blood coagulation tests like platelet count and haematocrit should be done in all patients receiving Lofh 5000IU Injection. Patients should inform the doctor that they are receiving Lofh 5000IU Injection before any surgery is scheduled.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Lofh 5000IU Injection:
Taking Alteplase with Lofh 5000IU Injection can increase the risk of bleeding.

How to manage the interaction:
Taking Lofh 5000IU Injection with Alteplase is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you have unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Lofh 5000IU Injection:
Taking Tenecteplase with Lofh 5000IU Injection can increase the risk of bleeding.

How to manage the interaction:
Taking Lofh 5000IU Injection with Tenecteplase is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you notice unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
HeparinOritavancin
Critical
How does the drug interact with Lofh 5000IU Injection:
Using Lofh 5000IU Injection with Oritavancin can make Lofh 5000IU Injection less effective as a therapy.

How to manage the interaction:
Lofh 5000IU Injection is not recommended within 120 hours (5 days) of taking oritavancin. Oritavancin can interfere with certain of the major coagulation tests used to assess Lofh 5000IU Injection's effectiveness and safety, it can be taken only if prescribed by a doctor. Do not discontinue any medications without a doctor's advice.
HeparinBazedoxifene
Critical
How does the drug interact with Lofh 5000IU Injection:
When Lofh 5000IU Injection is taken with bazedoxifene the effects of Lofh 5000IU Injection are reduced by bazedoxifene.

How to manage the interaction:
Taking Bazedoxifene with Lofh 5000IU Injection is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Lofh 5000IU Injection:
Taking Ticlopidine with Lofh 5000IU Injection can increase the risk of bleeding.

How to manage the interaction:
Taking Ticlopidine with Lofh 5000IU Injection is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Lofh 5000IU Injection:
Taking Mifepristone with Lofh 5000IU Injection can increase the risk of negative side effects.

How to manage the interaction:
Taking Lofh 5000IU Injection with Mifepristone is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Lofh 5000IU Injection:
Taking Lofh 5000IU Injection with Urokinase can increase the risk of bleeding.

How to manage the interaction:
Co-administration of Lofh 5000IU Injection with Urokinase can result in an interaction, but it can be taken if a doctor has advised it. However, if you have unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Lofh 5000IU Injection:
Sulfadiazine enhances the effects of Lofh 5000IU Injection by slowing its breakdown.

How to manage the interaction:
Co-administration of Sulfadiazine with Lofh 5000IU Injection can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without talking to a doctor.
How does the drug interact with Lofh 5000IU Injection:
Co-administration of Cefpodoxime with Lofh 5000IU Injection may enhance the levels or effects of Lofh 5000IU Injection by anticoagulation (preventing blood from clotting).

How to manage the interaction:
Although there is an interaction, Cefpodoxime can be taken with Lofh 5000IU Injection if prescribed by the doctor. Do not stop using any medications without a doctor's advice. Do not discontinue the medication without consulting a doctor.
HeparinDicoumarol
Severe
How does the drug interact with Lofh 5000IU Injection:
Coadministration of Lofh 5000IU Injection and dicumarol may increase the risk of bleeding.

How to manage the interaction:
Although taking Lofh 5000IU Injection and Dicoumarol together can cause an interaction, it can be taken if a doctor has suggested it. However, if you have unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, contact a doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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HEPARIN-5000IUHerbal products/medicines
Moderate

Drug-Food Interactions

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HEPARIN-5000IUHerbal products/medicines
Moderate
Common Foods to Avoid:
Garlic Pill

How to manage the interaction:
Taking Lofh 5000IU Injection along with herbs and supplements such as garlic, ginger, bilberry, danshen, piracetam, and ginkgo biloba can lead to an increased risk of bleeding Avoid taking herbs and supplements such as garlic, ginger, bilberry, danshen, piracetam, and ginkgo biloba while taking Lofh 5000IU Injection.

Habit Forming

No

Therapeutic Class

ANTICOAGULANTS / ANTITHROMBOTICS. ANTICONVULSANTS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

No, you are not recommended to take ibuprofen with Lofh 5000IU Injection as co-administration of these two medicines may increase the risk of bleeding more easily. However, please consult a doctor before taking other medicines with Lofh 5000IU Injection.

Yes, Lofh 5000IU Injection may increase potassium levels in the blood (hyperkalaemia), especially when given for a long period. Therefore, it is advised to inform your doctor if you are taking any medicines that increase potassium levels in the blood.

Yes, Lofh 5000IU Injection may cause bleeding. If you notice purple spots on the skin or unusual bruising, blood in urine, black tarry stools, unusual bleeding from gums or nose, please inform your doctor immediately as these are signs of bleeding more easily.

Yes, Lofh 5000IU Injection may cause allergic reactions such as fever, chills, difficulty in breathing, wheezing, blue shade to the lips, swelling of lips, and eyes. It is not necessary for everyone taking Lofh 5000IU Injection to experience an allergic reaction. However, if you notice any of these signs, please inform your doctor immediately.

Drug-Drug Interactions Checker List

  • SALICYLIC ACID
  • IBUPROFEN
  • INDOMETHACIN
  • PHENYLBUTAZONE
  • CELECOXIB
  • HYDROXYCHLOROQUINE
  • ABCIXIMAB
  • DIPYRIDAMOLE
  • DIGITALIS
  • TETRACYCLINE
  • NITROGLYCERIN

Special Advise

Regular blood tests are advised while taking Lofh 5000IU Injection to monitor prothrombin, platelets and coagulation time on regular basis.

Disease/Condition Glossary

Deep vein thrombosis (blood clots in legs) is a medical condition in which blood clots form in deep veins usually in the legs. The symptoms include leg pain or swelling.

Pulmonary embolism (blood clots in the lung) is a condition that occurs as the blood clots break and travel to the lungs from deep veins in the legs or other parts of the body. The symptoms of pulmonary embolism include chest pain, cough, and shortness of breath. 

Stroke is a condition where a blood clot restricts the flow of blood to your brain, causing brain cells to die and possibly resulting in permanent brain damage or death.

Transient ischaemic attack (TIA) is a condition also called 'mini-strokes', these have similar symptoms to a stroke, but the effects usually last less than 24 hours.

Heart attack is a condition where a blood clot blocks a blood vessel supplying your heart, starving it of oxygen and causing chest pain and sometimes death. Quick medication is advised to reduce the risk of serious conditions due to blood clots.

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