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  3. Medhep 25 Injection 5 ml

Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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Composition :

HEPARIN-5000IU

Manufacturer/Marketer :

Medcuris Healthcare Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Medhep 25 Injection 5 ml

Medhep 25 Injection 5 ml belongs to a class of drugs called anticoagulants or blood thinners. Medhep 25 Injection 5 ml is primarily used to prevent and treat deep vein thrombosis (blood clots in leg veins), pulmonary embolism (blood clots in the lung), stroke, Transient ischaemic attack (TIA), and heart attacks.  Deep vein thrombosis is a medical condition in which blood clots form in deep veins usually in the legs. Pulmonary embolism is a condition in which a blood clot blocks the arteries in the lungs. A stroke is a condition where a blood clot restricts the flow of blood to your brain, causing brain cells to die and possibly resulting in permanent brain damage or death. Transient ischaemic attack (TIA) is a condition also called 'mini-strokes', these have similar symptoms to a stroke, but the effects usually last less than 24 hours. Heart attack is a condition where a blood clot blocks a blood vessel supplying your heart, starving it of oxygen and causing chest pain and sometimes death.

Blood clots are formed to stop bleeding that occurs due to tissue injury. Though blood clots are useful to stop bleeding, they may be harmful when abnormally formed within blood vessels as they block blood vessels and inhibit blood flow to essential organs such as the brain, heart, or lungs. Medhep 25 Injection 5 ml works by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot) preventing blood clot formation.

Medhep 25 Injection 5 ml will be administered by a healthcare professional; do not self-administer. Some people may experience hemorrhage, thrombocytopenia (low platelets), hypersensitivity reactions, and elevations of liver enzyme (aminotransferase) levels. Most of these side effects of Medhep 25 Injection 5 ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Medhep 25 Injection 5 ml or any other medicines, please tell your doctor. It is not known whether Medhep 25 Injection 5 ml harms the baby or passes into breast milk in pregnancy and breastfeeding state. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Medhep 25 Injection 5 ml. Medhep 25 Injection 5 ml is not recommended for children below 2 months of age. If you have diabetes, kidney or liver problems, bleeding problems, or are aged above 60 years, inform your doctor before taking Medhep 25 Injection 5 ml.

Uses of Medhep 25 Injection 5 ml

Prevention of blood clots.

Directions for Use

Medhep 25 Injection 5 ml will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Medhep 25 Injection 5 ml is primarily used to prevent and treat blood clots by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot). Medhep 25 Injection 5 ml also reduces the risk of blood clots during surgeries (like heart surgery). Medhep 25 Injection 5 ml is used as an anticoagulant in blood transfusion and in a dialysis procedure.

Storage

Keep Medhep 25 Injection 5 ml out of the sight and reach of children.
Side effects of Medhep 25 Injection 5 ml
  • Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
  • Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
  • Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
  • Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
  • If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
  • In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
  • Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
  • If you experience severe bleeding or bruising, seek emergency medical attention immediately.

Drug Warnings

Use Medhep 25 Injection 5 ml cautiously in conditions with increased risk of bleeding. Use of name contraindicated in patients with HIT - Heparin-induced thrombosis (the abnormal formation of blood clots inside a blood vessel) and HITT (heparin-induced thrombocytopenia and thrombosis) might occur. Monitoring of blood coagulation tests like platelet count and haematocrit should be done in all patients receiving Medhep 25 Injection 5 ml. Patients should inform the doctor that they are receiving Medhep 25 Injection 5 ml before any surgery is scheduled.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Medhep 25 Injection 5 ml:
Taking Ticlopidine with Medhep 25 Injection 5 ml can increase the risk of bleeding.

How to manage the interaction:
Taking Ticlopidine with Medhep 25 Injection 5 ml is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Medhep 25 Injection 5 ml:
Taking Alteplase with Medhep 25 Injection 5 ml can increase the risk of bleeding.

How to manage the interaction:
Taking Medhep 25 Injection 5 ml with Alteplase is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you have unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Medhep 25 Injection 5 ml:
Taking Mifepristone with Medhep 25 Injection 5 ml can increase the risk of negative side effects.

How to manage the interaction:
Taking Medhep 25 Injection 5 ml with Mifepristone is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
HeparinOritavancin
Critical
How does the drug interact with Medhep 25 Injection 5 ml:
Using Medhep 25 Injection 5 ml with Oritavancin can make Medhep 25 Injection 5 ml less effective as a therapy.

How to manage the interaction:
Medhep 25 Injection 5 ml is not recommended within 120 hours (5 days) of taking oritavancin. Oritavancin can interfere with certain of the major coagulation tests used to assess Medhep 25 Injection 5 ml's effectiveness and safety, it can be taken only if prescribed by a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Medhep 25 Injection 5 ml:
Taking Tenecteplase with Medhep 25 Injection 5 ml can increase the risk of bleeding.

How to manage the interaction:
Taking Medhep 25 Injection 5 ml with Tenecteplase is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you notice unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
HeparinBazedoxifene
Critical
How does the drug interact with Medhep 25 Injection 5 ml:
When Medhep 25 Injection 5 ml is taken with bazedoxifene the effects of Medhep 25 Injection 5 ml are reduced by bazedoxifene.

How to manage the interaction:
Taking Bazedoxifene with Medhep 25 Injection 5 ml is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
HeparinEdoxaban
Severe
How does the drug interact with Medhep 25 Injection 5 ml:
Taking Edoxaban with Medhep 25 Injection 5 ml may increase the risk of bleeding.

How to manage the interaction:
Co-administration of Medhep 25 Injection 5 ml with Edoxaban can result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor, if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop using any medications without a doctor's advice.
HeparinDicoumarol
Severe
How does the drug interact with Medhep 25 Injection 5 ml:
Coadministration of Medhep 25 Injection 5 ml and dicumarol may increase the risk of bleeding.

How to manage the interaction:
Although taking Medhep 25 Injection 5 ml and Dicoumarol together can cause an interaction, it can be taken if a doctor has suggested it. However, if you have unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, contact a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Medhep 25 Injection 5 ml:
Coadministration of Medhep 25 Injection 5 ml and Apixaban co-administration may raise the risk of bleeding.

How to manage the interaction:
Even though combining Medhep 25 Injection 5 ml and Apixaban may cause an interaction, it is still possible to take it if a doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without consulting a doctor, never stop taking any medications.
How does the drug interact with Medhep 25 Injection 5 ml:
Co-administration of Ibrutinib with Medhep 25 Injection 5 ml can increase the risk of bleeding.

How to manage the interaction:
There may be a possibility of interaction between Ibrutinib and Medhep 25 Injection 5 ml, but it can be taken if prescribed by a doctor. However, consult a doctor, if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Side Effects of Medhep 25 Injection 5 ml

  • Red itchy patches or lumps at the site of injection
  • Unusual bleeding
  • Skin redness

Habit Forming

No

Therapeutic Class

ANTICOAGULANTS / ANTITHROMBOTICS. ANTICONVULSANTS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

No, you are not recommended to take ibuprofen with Medhep 25 Injection 5 ml as co-administration of these two medicines may increase the risk of bleeding more easily. However, please consult a doctor before taking other medicines with Medhep 25 Injection 5 ml.

Yes, Medhep 25 Injection 5 ml may increase potassium levels in the blood (hyperkalaemia), especially when given for a long period. Therefore, it is advised to inform your doctor if you are taking any medicines that increase potassium levels in the blood.

Yes, Medhep 25 Injection 5 ml may cause bleeding. If you notice purple spots on the skin or unusual bruising, blood in urine, black tarry stools, unusual bleeding from gums or nose, please inform your doctor immediately as these are signs of bleeding more easily.

Yes, Medhep 25 Injection 5 ml may cause allergic reactions such as fever, chills, difficulty in breathing, wheezing, blue shade to the lips, swelling of lips, and eyes. It is not necessary for everyone taking Medhep 25 Injection 5 ml to experience an allergic reaction. However, if you notice any of these signs, please inform your doctor immediately.

Drug-Drug Interactions Checker List

  • SALICYLIC ACID
  • IBUPROFEN
  • INDOMETHACIN
  • PHENYLBUTAZONE
  • CELECOXIB
  • HYDROXYCHLOROQUINE
  • ABCIXIMAB
  • DIPYRIDAMOLE
  • DIGITALIS
  • TETRACYCLINE
  • NITROGLYCERIN

Special Advise

Regular blood tests are advised while taking Medhep 25 Injection 5 ml to monitor prothrombin, platelets and coagulation time on regular basis.

Disease/Condition Glossary

Deep vein thrombosis (blood clots in legs) is a medical condition in which blood clots form in deep veins usually in the legs. The symptoms include leg pain or swelling.

Pulmonary embolism (blood clots in the lung) is a condition that occurs as the blood clots break and travel to the lungs from deep veins in the legs or other parts of the body. The symptoms of pulmonary embolism include chest pain, cough, and shortness of breath. 

Stroke is a condition where a blood clot restricts the flow of blood to your brain, causing brain cells to die and possibly resulting in permanent brain damage or death.

Transient ischaemic attack (TIA) is a condition also called 'mini-strokes', these have similar symptoms to a stroke, but the effects usually last less than 24 hours.

Heart attack is a condition where a blood clot blocks a blood vessel supplying your heart, starving it of oxygen and causing chest pain and sometimes death. Quick medication is advised to reduce the risk of serious conditions due to blood clots.

Have a query?

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Alcohol

Caution

You are recommended to avoid consumption of alcohol with Medhep 25 Injection 5 ml as it may cause severe bleeding in the stomach and harmful side effects to the liver.

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Pregnancy

Caution

Medhep 25 Injection 5 ml is a Category C pregnancy drug and should be given to pregnant women only if clearly needed and has more benefits than risks. Preservative-free forms are preferred in pregnant women as preservatives such as benzyl alcohol may cross the placenta.

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Breast Feeding

Caution

Medhep 25 Injection 5 ml should be given to breastfeeding mothers only if clearly needed and has more benefits than risks.

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Driving

Safe if prescribed

Medhep 25 Injection 5 ml usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Medhep 25 Injection 5 ml should be given with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Medhep 25 Injection 5 ml should be given with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Medhep 25 Injection 5 ml is not recommended for children below 2 months.

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