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Reviewed By Sunny S , MBBS
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Manufacturer/Marketer :

Ajanta Pharma Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Isorus Tablet

Isorus Tablet belongs to a group of heart-related medicines called 'vasodilators used to treat heart failure. Heart failure occurs when the heart muscle does not pump blood normally, including shortness of breath, swollen legs, fatigue and increased heartbeat. In this condition, the heart becomes too weak and cannot pump enough blood and oxygen to the organs and tissues of our body. 

Isorus Tablet is a fixed-dose combination composed of two medicines: Isosorbide dinitrate and Hydralazine. Isosorbide dinitrate is a group of drugs known as nitrates that relax the heart's muscles and widen the heart's veins and arteries for easy flow of blood to every part of our body. It is used to treat angina (chest pain) and other heart-related diseases due to a shortage of oxygen and blood. Hydralazine belongs to a group of drugs known as vasodilators which help lowers raised blood pressure by relaxing and widening the heart's muscles. 

Isorus Tablet is available in the form of oral tablets. Take Isorus Tablet as your doctor has prescribed it. Doses of the Isorus Tablet will decide by your doctor, but generally, start with low doses and increase the amount. In some cases, Isorus Tablet can cause side effects like headache, nausea, dizziness, and lightheadedness (feeling faint). Most of these side effects of Isorus Tablet do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.

If you are known to be allergic to Isorus Tablet or any other medicines, please inform your doctor. Before taking Isorus Tablet , let your doctor know if you have had a heart attack within the last 30 days, low blood pressure, stroke (inadequate blood supply in the brain that causes damage to the brain), or high pressure within the brain. Please do not stop taking Isorus Tablet on your own, which may lead to the recurrence of symptoms or worsen the condition.

Uses of Isorus Tablet

Heart failure

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Isorus Tablet belongs to a group of vasodilators used to treat heart failure. Isorus Tablet is a fixed-dose combination composed of two medicines: Isosorbide dinitrate and Hydralazine. Isosorbide dinitrate belongs to a group of drugs known as nitrates. Isosorbide dinitrate relaxes the heart's muscles and stretches or enlarges the heart's veins and arteries. It treats angina (chest pain) and other heart-related diseases. Hydralazine belongs to a group of drugs known as vasodilators which help lowers raised blood pressure by relaxing and widening the heart's blood vessels.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Isorus Tablet if you have low blood pressure because even a low dose of Isorus Tablet may produce low blood pressure. If you are pregnant or planning any pregnancy, let your doctor know about this before taking Isorus Tablet as it crosses the placenta and can affect the unborn baby (fetus). Do not drive by using this Isorus Tablet because it produces dizziness that may cause an accident. You may experience tingling or numbness, so your doctor may prescribe a vitamin B6 supplement (pyridoxine). Hydralazine passes into breast milk, so its use in lactating mothers should be avoided. 

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Isorus Tablet:
Coadministration of Isorus Tablet and Sildenafil can increase the risk of low blood pressure.

How to manage the interaction:
Taking Isorus Tablet and Sildenafil together is generally avoided as it can lead to an interaction, it can be taken only if advised by your doctor. However, if you experience dizziness, lightheadedness, fainting, headache, flushing, heart palpitations, and priapism (prolonged and painful erection unrelated to sexual activity) contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Isorus Tablet:
Taking Avanafil with Isorus Tablet can cause low blood pressure.

How to manage the interaction:
Taking Isorus Tablet with Avanafil is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience dizziness, lightheadedness, fainting, headache, flushing, heart palpitations, priapism in males (persistent and painful erection unrelated to sexual activity). Do not discontinue any medications without consulting a doctor.
How does the drug interact with Isorus Tablet:
Taking Riociguat with Isorus Tablet may lead to excessively low blood pressure.

How to manage the interaction:
Taking Isorus Tablet with Riociguat is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience dizziness, lightheadedness, fainting, headache, flushing, heart palpitations, priapism in males (persistent and painful erection unrelated to sexual activity). Do not discontinue any medications without consulting a doctor.
How does the drug interact with Isorus Tablet:
Taking Tadalafil with Isorus Tablet can increase the risk or severity of low blood pressure.

How to manage the interaction:
Taking Isorus Tablet with Tadalafil is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, or heart palpitations. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Isorus Tablet:
Coadministration of Isorus Tablet and cabergoline may decrease your blood pressure.

How to manage the interaction:
Co-administration of Isorus Tablet with Cabergoline can result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these signs - headache, dizziness, feeling lightheaded, or fainting, contact your doctor immediately. Do not stop using any medications without talking to your doctor.
How does the drug interact with Isorus Tablet:
Taking Isorus Tablet with cabergoline can increase the effects of Cabergoline.

How to manage the interaction:
Although taking Isorus Tablet and cabergoline together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. Do not stop using any medications without consulting doctor.
How does the drug interact with Isorus Tablet:
Taking Isorus Tablet with levobupivacaine may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although taking Isorus Tablet and levobupivacaine together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
Isosorbide dinitrateSodium nitrite
Severe
How does the drug interact with Isorus Tablet:
Taking Isorus Tablet with sodium nitrite may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although taking Isorus Tablet and sodium nitrite together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
How does the drug interact with Isorus Tablet:
Combining Bupivacaine with Isorus Tablet can increase the risk of methemoglobinemia(a rare condition that can lead to oxygen deprivation in tissues and vital organs due to reduced oxygen-carrying capacity of the blood).

How to manage the interaction:
Co-administration of Bupivacaine with Isorus Tablet can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms like grey discolouration of the skin, abnormal blood colouration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, confusion, consult a doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Isorus Tablet:
Taking Isorus Tablet with chloroprocaine may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although taking Isorus Tablet and chloroprocaine together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitations, anxiety, or confusion. Do not stop using any medications without consulting doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Follow a cholesterol-lowering diet.
  • Consume low salt and a low-fat diet.
  • Exercise regularly. It helps in maintaining proper weight and lowers cholesterol.
  • Limit salt and sugar intake.
  • Avoid smoking and alcohol consumption.
  • Choose healthy fats and cut down on trans fat.
  • Include omega-3 fatty acids, fibre-rich food, fruits, and vegetables.
  • Get active by doing physical activities such as swimming, brisk walking, or jogging. Take the stairs instead of elevators/lifts.

Habit Forming

No

Therapeutic Class

VASODILATORS

Isorus Tablet Substitute

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Isorus Tablet can sometimes cause headaches, generally at the start of the treatment. As the treatment continues, your headache may become less severe and frequent. If the headache continues, inform your doctor.

Yes, the use of Isorus Tablet can make you feel dizzy. This may often occur when you suddenly rise from a sitting or lying position. To lower the chance of feeling dizzy (faint) or passing out, rise slowly if you have been lying down or sitting.

No, keep using the Isorus Tablet as advised by your doctor, even if you feel well. Stopping the Isorus Tablet suddenly may lead to serious complications of heart failure.

Isorus Tablet is a fixed-dose combination composed of two medicines: Isosorbide dinitrate and Hydralazine. Isosorbide dinitrate is a group of drugs known as nitrates that relax the heart's muscles and widen the heart's veins and arteries for easy flow of blood to every part of our body. It is used to treat angina (chest pain) and other heart-related diseases due to a shortage of oxygen and blood. Hydralazine belongs to a group of drugs known as vasodilators which help lowers raised blood pressure by relaxing and widening the heart's muscles.

Keep this medicine tightly closed in the container or the pack it came in. Store it according to the instructions mentioned on the pack or label. Dispose of unused medicine. Make sure pets, children, and other people do not consume it.

Drug-Drug Interactions Checker List

  • ERGOTAMINE
  • SILDENAFIL
  • TADALAFIL
  • IBUPROFEN
  • NAPROXEN

Special Advise

 

Disease/Condition Glossary

Heart failure occurs when the heart's muscle does not properly pump blood to the body parts. Heart failure symptoms include shortness of breath, swollen legs, fatigue (lack of energy or feeling of tiredness), and increased heartbeat. In this condition, the heart becomes too weak and does not pump enough. It is a life-threatening condition and requires immediate hospitalization.

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