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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

Online payment accepted

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Whats That

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Composition :

OLAPARIB-100MG

Manufacturer/Marketer :

Hetero Healthcare Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Lynza 100 mg Tablet 30's

Lynza 100 mg Tablet 30's belongs to a group of medicines known as 'anti-cancer' drugs used to treat various cancers, including Ovarian, breast, pancreatic, and prostate. Cancer is a condition where cells in a specific body part grow and reproduce uncontrollably. The cancerous cells can attack and destroy surrounding healthy tissue, including organs.

Lynza 100 mg Tablet 30's contains Olaparib, a targeted drug called a PARP inhibitor. PARP (polyadenosine 5’-diphosphoribose polymerase) is a protein that helps damaged cells repair themselves. Olaparib stops PARP working. Some cancer cells rely on PARP to keep their DNA healthy. So, the cancer cells die when Olaparib stops PARP from repairing DNA damage.

Use this medicine as directed by your doctor. You may sometimes experience shortness of breath (dyspnoea), feeling very tired, pale skin or fast heartbeat, anaemia, feeling sick (nausea), being sick (vomiting), indigestion or heartburn (dyspepsia), loss of appetite, headache, changes in taste of foods (dysgeusia), feeling dizzy, cough and diarrhoea. Most of these side effects may gradually resolve over time. However, if the side effects persist or worsen, consult your doctor.

To treat your condition effectually, continue taking Lynza 100 mg Tablet 30's for as long as your doctor has prescribed. Do not stop using the Lynza 100 mg Tablet 30's midway. Talk to your doctor before taking Lynza 100 mg Tablet 30's if you have severe allergic reactions to Lynza 100 mg Tablet 30's or other medicines or suffer from severe infections, renal dysfunction, hepatic disorders and blood cell counts are too low. Avoid taking Lynza 100 mg Tablet 30's if you are pregnant or breastfeeding because this Lynza 100 mg Tablet 30's can cause harmful effects on the unborn baby. Both women and men using this Lynza 100 mg Tablet 30's should use birth control to avoid pregnancy. While on Lynza 100 mg Tablet 30's treatment, you should avoid eating grapefruit, Seville oranges or consuming grapefruit juice since it can affect how the medicine works.

Uses of Lynza 100 mg Tablet 30's

Cancer (Ovarian cancer, breast cancer, pancreatic cancer, and prostate cancer)

Directions for Use

Swallow it as a whole with water; do not crush or chew it.

Medicinal Benefits

Lynza 100 mg Tablet 30's contains Olaparib, a targeted drug called a PARP inhibitor. PARP is a protein that helps damaged cells to repair themselves. Olaparib stops PARP working. Some cancer cells rely on PARP to keep their DNA healthy. So, the cancer cells die when Olaparib stops PARP from repairing DNA damage. Thus, it treats various cancers, including Ovarian, breast, pancreatic, and prostate. It can be used alone or with other chemotherapy drugs, depending on your type of cancer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Always take this medicine exactly as your doctor or healthcare professional has told you. To treat your condition effectually, continue taking Lynza 100 mg Tablet 30's for as long as your doctor has prescribed. Do not stop Lynza 100 mg Tablet 30's midway. Talk to your doctor before taking Lynza 100 mg Tablet 30's if you have severe allergic reactions to Lynza 100 mg Tablet 30's or other medicines or suffer from any medical illness. Avoid taking Lynza 100 mg Tablet 30's if you are pregnant or breastfeeding because this Lynza 100 mg Tablet 30's can cause harmful effects on the unborn baby. Both women and men using this Lynza 100 mg Tablet 30's should use birth control to avoid pregnancy. Do not start Lynza 100 mg Tablet 30's unless patients have recovered from haematological damage induced by previous chemotherapy (Grade 1). Check full blood count for cytopenia at baseline and monthly afterwards for clinically significant changes during treatment. For persistent haematological toxicity, discontinue Lynza 100 mg Tablet 30's and monitor blood count weekly until recovery. Do not receive any immunization or vaccination without your doctor's approval while taking the Lynza 100 mg Tablet 30's.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Lynza 100 mg Tablet:
Taking filgrastim together with Lynza 100 mg Tablet can reduce the effects of filgrastim.

How to manage the interaction:
Co-administration of Filgrastim with Lynza 100 mg Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Lynza 100 mg Tablet:
Fluconazole may increase the blood levels of Lynza 100 mg Tablet. This can increase the risk and/or severity of side effects such as nausea, vomiting, diarrhea, indigestion, loss of appetite, abdominal pain or discomfort, lung problems, and impaired bone marrow function resulting in low blood cell count.

How to manage the interaction:
Although there is a possible interaction, fluconazole can be taken with Lynza 100 mg Tablet if prescribed by the doctor. Consult the doctor if you experience paleness, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination.
OlaparibLetermovir
Severe
How does the drug interact with Lynza 100 mg Tablet:
Using Letermovir and Lynza 100 mg Tablet can increase the blood levels of Lynza 100 mg Tablet. This can increase the risk and/or severity of side effects such as nausea, vomiting, diarrhea, indigestion, loss of appetite, abdominal pain or discomfort, lung problems, and impaired bone marrow function resulting in low numbers of different types of blood cells.

How to manage the interaction:
Combining Letermovir and Lynza 100 mg Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like paleness, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact the doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Lynza 100 mg Tablet:
Coadministration of Phenytoin and Lynza 100 mg Tablet may decrease the blood levels of Lynza 100 mg Tablet, which may make Lynza 100 mg Tablet less effective.

How to manage the interaction:
Although taking Phenytoin and Lynza 100 mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. Without consulting a doctor, never stop taking any drugs.
How does the drug interact with Lynza 100 mg Tablet:
When Bicalutamide is taken with Lynza 100 mg Tablet, it can increase the blood levels and effects of Lynza 100 mg Tablet.

How to manage the interaction:
Although there is a possible interaction between Bicalutamide and Lynza 100 mg Tablet, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Lynza 100 mg Tablet:
When Lynza 100 mg Tablet is taken with Fosaprepitant, can increase the levels of Lynza 100 mg Tablet in the body. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Lynza 100 mg Tablet with Fosaprepitant together can result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these symptoms paleness, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, it's a good idea to call a doctor right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Lynza 100 mg Tablet:
Using Dronedarone and Lynza 100 mg Tablet can increase the blood levels of Lynza 100 mg Tablet. This can increase the risk and/or severity of side effects such as nausea, vomiting, diarrhea, indigestion, loss of appetite, abdominal pain or discomfort, lung problems, and impaired bone marrow function resulting in low numbers of different types of blood cells.

How to manage the interaction:
Combining Dronedarone and Lynza 100 mg Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like paleness, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact the doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Lynza 100 mg Tablet:
Taking Rifabutin and Lynza 100 mg Tablet may significantly reduce the blood levels of Lynza 100 mg Tablet, which may make the medication less effective.

How to manage the interaction:
Although taking Lynza 100 mg Tablet and Rifabutin together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Lynza 100 mg Tablet:
Using Atazanavir and Lynza 100 mg Tablet can increase the blood levels of Lynza 100 mg Tablet. This can increase the risk and/or severity of side effects Lynza 100 mg Tablet.

How to manage the interaction:
Combining Atazanavir and Lynza 100 mg Tablet can lead to an interaction, but it can be taken if your doctor advises. However, if you experience paleness, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhoea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact the doctor immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Lynza 100 mg Tablet:
Taking carbamazepine with Lynza 100 mg Tablet can reduce the blood levels of Lynza 100 mg Tablet.

How to manage the interaction:
Although taking Lynza 100 mg Tablet and Carbamazepine together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast, fried, processed meats, refined carbs and added sugars.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Lynza 100 mg Tablet 30's contains Olaparib, a targeted drug called a PARP inhibitor. PARP is a protein that helps damaged cells to repair themselves. Olaparib stops PARP working. Some cancer cells rely on PARP to keep their DNA healthy. So, the cancer cells die when Olaparib stops PARP from repairing DNA damage.

If you are allergic to Olaparib or any other ingredients in this medication, are breastfeeding, or have too low blood cell counts, you should not use Lynza 100 mg Tablet 30's.

Yes, Lynza 100 mg Tablet 30's can cause low neutrophils levels, a type of white blood cells that help fight infections. If your white blood cells become low, you can be at higher risk for infections. Tell your doctor if you develop a fever or have an infection.

Do not have immunizations/vaccinations without talking to your doctor first. Also, avoid contact with people who recently had immunizations /vaccinations.

Yes, Olaparib was generally a well-tolerated medication. Take Lynza 100 mg Tablet 30's pills exactly as directed by your healthcare provider. Do not change your dose or stop taking Lynza 100 mg Tablet 30's unless your healthcare physician instructs you. If you encounter side symptoms, your healthcare provider may temporarily discontinue your Lynza 100 mg Tablet 30's therapy or adjust your Lynza 100 mg Tablet 30's dose.

Drug-Drug Interactions Checker List

  • AMPRENAVIR
  • DARUNAVIR
  • APREPITANT
  • BCG VACCINE
  • DENGUE VACCINE
  • MUMPS (LIVE ATTENUATED)
  • CIPROFLOXACIN
  • FLUCONAZOLE
  • ITRACONAZOLE

Special Advise

  • Pregnancy testing is recommended for females of reproductive potential prior to initiating treatment with Lynza 100 mg Tablet 30's.
  • Lynza 100 mg Tablet 30's should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking Lynza 100 mg Tablet 30's.
  • Monitor complete blood count for cytopenia at baseline and monthly for clinically significant changes during treatment.
  • Your doctor may get routine blood tests done to monitor your liver function, electrolyte levels, and blood cell count in your blood.
  • Peripheral blood counts should be frequently monitored during Lynza 100 mg Tablet 30's treatment and, when appropriate, until recovery is achieved.
  • Do not donate sperm during treatment with Lynza 100 mg Tablet 30's for three months after your last dose.

Disease/Condition Glossary

Cancer: Cancer is a condition where cells in a specific body part grow and reproduce uncontrollably. The cancerous cells can invade and destroy surrounding healthy tissue, including organs. Cancer sometimes begins in one body part before spreading to other areas.

Ovarian cancer: Ovarian cancer begins in the ovaries (one of a pair of female reproductive glands in which the ova, or eggs, are formed).

Breast cancer: Breast cancer is a type of cancer that develops in breast cells stimulated by a female sex hormone called estrogen. Breast cancer may form in lobules (glands that produce milk), ducts of the breast (the pathway that brings milk from glands to the nipple), and the fatty tissue or the fibrous connective tissue within the breast. The tumour cells invade other healthy breast cells and travel to lymph nodes, a primary pathway for the cancer cells to move to other body parts. Symptoms of breast cancer include a lump in the breast or tissue thickening, which feels different than the normal surrounding tissues, breast pain, redness, swelling, and nipple discharge other than breast milk.

Prostate cancer: Prostate cancer is a type of cancer that only occurs in men and affects the prostate gland, a tiny gland under the bladder that produces semen. Inability to urinate easily, pain, numbness, or sexual issues are among the symptoms. For men, it is the most typical type of cancer. Although the exact cause of prostate cancer is unknown, it may be brought on by family history, chemical exposure, or both. Prostate cancer risk factors include a family history of the disease, advanced age, obesity, and genetic changes.

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