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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Non returnable*
COD available

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Composition :

ONDANSETRON-2MG

Manufacturer/Marketer :

Fresh Focus Consumer Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Ondatriz 4Mg/2Ml Inj

Ondatriz 4Mg/2Ml Inj belongs to a class of drugs called antiemetics used to prevent nausea and vomiting during chemotherapy. Nausea is a feeling of uneasiness of the stomach that often comes before vomiting. On the other hand, vomiting is the forcible voluntary or involuntary emptying of stomach contents through the mouth.

Ondatriz 4Mg/2Ml Inj contains Ondansetron which works by blocking the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it prevents nausea and vomiting. 

Ondatriz 4Mg/2Ml Inj will be administered by a healthcare professional. Do not self-administer. In some cases, Ondatriz 4Mg/2Ml Inj may cause headache, constipation, a feeling of warmth or flushing, redness, and irritation at the site of injection. Most of these side effects of Ondatriz 4Mg/2Ml Inj do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. 

If you are allergic to Ondansetron, Palanosetron, Granisetron, or any other medicines, please tell your doctor. Ondatriz 4Mg/2Ml Inj should be given to children only in doses advised by the doctor based on the child’s body weight or body surface area. If you are pregnant or breastfeeding, must inform your doctor before receiving Ondatriz 4Mg/2Ml Inj.

Uses of Ondatriz 4Mg/2Ml Inj

Prevent nausea and vomiting

Directions for Use

Ondatriz 4Mg/2Ml Inj will be administered by a healthcare professional. Do not self-administer.

Medicinal Benefits

Ondatriz 4Mg/2Ml Inj contains Ondansetron that blocks the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it prevents nausea and vomiting caused by chemotherapy in adults and children and also after surgery. Additionally, Ondatriz 4Mg/2Ml Inj can be used to prevent nausea and vomiting caused by radiotherapy for cancer in adults.

Storage

Store in a cool and dry place away from sunlight
Side effects of Ondatriz 4Mg/2Ml Inj
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Drink plenty of fluids to stay hydrated and replace the lost electrolytes.
  • Eat small, frequent meals of bland foods like crackers, toast, or plain rice.
  • Avoid heavy or fatty foods that can worsen nausea.
  • Use relaxation techniques like deep breathing or meditation to manage stress and anxiety.
  • Minimize exposure to strong smells or odors that can trigger nausea.
  • Ensure good airflow in the room by keeping it well-ventilated and maintaining a comfortable temperature.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.

Drug Warnings

If you are allergic to Ondansetron, Palanosetron, Granisetron, or any other medicines, please tell your doctor. Ondatriz 4Mg/2Ml Inj should be given to children only in doses as advised by the doctor based on the child’s body weight or body surface area. Ondatriz 4Mg/2Ml Inj should be used during pregnancy or breastfeeding after consultation with a doctor. If you have problems with levels of sodium, magnesium, and potassium salts in your blood, inform your doctor before taking Ondatriz 4Mg/2Ml Inj. 

Drug-Drug Interactions

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OndansetronZiprasidone
Critical
OndansetronVortioxetine
Severe

Drug-Drug Interactions

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OndansetronZiprasidone
Critical
How does the drug interact with Ondatriz 4Mg/2Ml Inj:
Taking Ondatriz 4Mg/2Ml Inj with Ziprasidone can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Ondatriz 4Mg/2Ml Inj with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
OndansetronVortioxetine
Severe
How does the drug interact with Ondatriz 4Mg/2Ml Inj:
When Ondatriz 4Mg/2Ml Inj, is taken with Vortioxetine it can cause serotonin syndrome (A condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Co-administration of Ondatriz 4Mg/2Ml Inj along with Vortioxetine can lead to an interaction, it can be taken if recommended by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, a shaking sensation, incoordination, stomach cramp, nausea, vomiting, and diarrhea, see a doctor. Do not discontinue any medications without a doctor's advice.
OndansetronCitalopram
Severe
How does the drug interact with Ondatriz 4Mg/2Ml Inj:
When Ondatriz 4Mg/2Ml Inj, is taken with citalopram, the risk of serotonin syndrome increases. (a condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Co-administration of Ondatriz 4Mg/2Ml Inj along with citalopram can lead to an interaction, it can be taken if recommended by a doctor. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach pain, nausea, vomiting, and diarrhea while taking these medications, consult the doctor. Do not discontinue any medications without a doctor's advice.
OndansetronClozapine
Severe
How does the drug interact with Ondatriz 4Mg/2Ml Inj:
Although it is a very rare adverse effect, taking Ondatriz 4Mg/2Ml Inj with clozapine increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Co-administration of Ondatriz 4Mg/2Ml Inj along with clozapine can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
OndansetronParoxetine
Severe
How does the drug interact with Ondatriz 4Mg/2Ml Inj:
When Ondatriz 4Mg/2Ml Inj is taken with paroxetine, can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Co-administration of Ondatriz 4Mg/2Ml Inj along with paroxetine can result in an interaction, it can be taken if a doctor has advised it. However, if you have sudden dizziness, lightheadedness, fainting, confusion, hallucination, fits, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles, or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea, or fast or rapid heartbeats during therapy, consult the doctor. Do not stop using any medication without consulting a doctor.
OndansetronFurazolidone
Severe
How does the drug interact with Ondatriz 4Mg/2Ml Inj:
When Ondatriz 4Mg/2Ml Inj, is taken with furazolidone it can cause serotonin syndrome. (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Ondatriz 4Mg/2Ml Inj along with furazolidone can lead to an interaction, it can be taken if recommended by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, a shaking sensation, incoordination, stomach cramp, nausea, vomiting, and diarrhea, see a doctor. Do not discontinue any medications without a doctor's advice.
OndansetronLinezolid
Severe
How does the drug interact with Ondatriz 4Mg/2Ml Inj:
When Ondatriz 4Mg/2Ml Inj is taken with linezolid it can cause serotonin syndrome. (a condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Co-administration of Ondatriz 4Mg/2Ml Inj along with linezolid can lead to an interaction, it can be taken if recommended by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, incoordination, stomach pain, nausea, vomiting, and diarrhea, consult the doctor. Do not discontinue any medications without consulting a doctor.
OndansetronMaprotiline
Severe
How does the drug interact with Ondatriz 4Mg/2Ml Inj:
When Ondatriz 4Mg/2Ml Inj is taken with maprotiline, can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Co-administration of Ondatriz 4Mg/2Ml Inj along with maprotiline can result in an interaction, it can be taken if a doctor has advised it. However, if you have sudden dizziness, lightheadedness, fainting, confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles, or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea, or fast or rapid heartbeats during therapy, consult the doctor. Do not stop using any medications without talking to a doctor.
OndansetronBupropion
Severe
How does the drug interact with Ondatriz 4Mg/2Ml Inj:
When bupropion, is combined with Ondatriz 4Mg/2Ml Inj it can cause serotonin syndrome. (a condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Co-administration of Ondatriz 4Mg/2Ml Inj along with bupropion can lead to interaction, it can be taken if recommended by a doctor. If you experience confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, a shaking sensation, incoordination, stomach cramp, nausea, vomiting, and diarrhea consult a doctor. Do not discontinue any medications without consulting a doctor.
OndansetronPhenelzine
Severe
How does the drug interact with Ondatriz 4Mg/2Ml Inj:
When Ondatriz 4Mg/2Ml Inj, is taken with phenelzine it can cause serotonin syndrome. (a condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Co-administration of Ondatriz 4Mg/2Ml Inj along with phenelzine can lead to an interaction, it can be taken if recommended by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, a shaking sensation, incoordination, stomach cramp, nausea, vomiting, and diarrhea, see a doctor. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy and a low-fat diet, especially in small portions, as it will be easy for digestion. Avoid eating over-sweet food and include more salty food, especially if you have been vomiting.
  • Drink any other liquid at least 30 minutes after eating food. 
  • If the smell of food makes you feel sick (vomit), do not cook food as it may worsen your condition. Let someone else do the cooking or use prepared food from the freezer.

Habit Forming

No

Therapeutic Class

ANTIEMETICS

Ondatriz 4Mg/2Ml Inj Substitute

Substitutes safety advice
  • Emeset 4 mg Injection 10X2 ml

    by AYUR

    12.02per tablet
  • Ondem Injection 10 x 2 ml

    by Others

    12.02per tablet
  • Emeset Injection 10X4 ml

    by Others

    24.03per tablet
  • Ondem Injection 10 x 4 ml

    by Others

    23.50per tablet
  • Emeset 2 Injection 2 ml

    by Others

    5.85per tablet

Author Details

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Ondatriz 4Mg/2Ml Inj works by blocking the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it prevents nausea and vomiting.

You are not recommended to take erythromycin with Ondatriz 4Mg/2Ml Inj as it may increase the risk of severe irregular heart rhythm. However, please consult your doctor before taking other medicines with Ondatriz 4Mg/2Ml Inj.

Ondatriz 4Mg/2Ml Inj may cause constipation as a side effect. It is not necessary for everyone taking Ondatriz 4Mg/2Ml Inj to experience this side effect. However, if the condition persists or worsens, please consult a doctor.

Ondatriz 4Mg/2Ml Inj should be used with caution in patients suffering from liver problems. However, inform your doctor if you have any liver problems before taking Ondatriz 4Mg/2Ml Inj so that the dose may be adjusted appropriately.

Yes, Ondatriz 4Mg/2Ml Inj may be used to prevent nausea and vomiting after surgery. Ondatriz 4Mg/2Ml Inj blocks serotonin (a chemical) action which is responsible for causing nausea and vomiting.

Drug-Drug Interactions Checker List

  • PHENYTOIN
  • CARBAMAZEPINE
  • RIFAMPICIN
  • ERYTHROMYCIN
  • KETOCONAZOLE
  • TRAMADOL
  • CITALOPRAM
  • FLUOXETINE
  • FLUVOXAMINE
  • PAROXETINE
  • SERTRALINE
  • ESCITALOPRAM
  • DULOXETINE
  • VENLAFAXINE
  • HALOPERIDOL

Disease/Condition Glossary

Nausea and vomiting: Nausea is a feeling of uneasiness of the stomach that often comes before vomiting. On the other hand, vomiting is the forcible voluntary or involuntary emptying of stomach contents through the mouth. In short, nausea and vomiting are not diseases but are symptoms of many conditions like infections, motion sickness, an early stage of pregnancy, and gastroparesis (slow stomach emptying). A receptor located in the brain known as the chemoreceptor trigger zone (CTZ) controls vomiting.

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