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Reviewed By Sunny S , MBBS
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Non returnable*
COD available

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Manufacturer/Marketer :

Mitis Biomedics Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Pubnol-ET Tablet

Pubnol-ET Tablet is a combination drug containing 'anti-anxiety medication,' primarily used to treat anxiety disorder. An anxiety disorder is a mental condition characterized by feelings of excessive fear or worry that affect an individual's daily activities. High levels of anxiety can cause panic attacks, with intense feelings of nervousness, fear, sudden onset of sweating, hyperventilation, fast heartbeat, and skin flushing.

Pubnol-ET Tablet contains Etizolam (benzodiazepine) and Propanolol (a beta-blocker), used to treat anxiety. Etizolam works by increasing the action of a chemical messenger GABA, which suppresses the excessive and abnormal activity of nerve cells in the brain. Propanolol works by blocking a certain chemical messenger in the heart and blood vessels, reducing blood pressure, heart rate, and workload on the heart.

Take Pubnol-ET Tablet as prescribed by your doctor. You are advised to take Pubnol-ET Tablet for as long as your doctor has prescribed it for you, depending upon your medical condition. In some cases, you may experience confusion, slow heart rate, memory impairment, tiredness, cold extremities, uncoordinated body movements, drowsiness. Most of these side effects of Pubnol-ET Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.  

If you are pregnant, planning to become pregnant, or breastfeeding, please inform your doctor Pubnol-ET Tablet contains Etizolam, a habit-forming drug, so take it in dose and duration prescribed by a doctor. Do not stop taking Pubnol-ET Tablet even if you feel better as it may lead to withdrawal symptoms. Pubnol-ET Tablet is known to cause drowsiness, so do not drive or operate machinery. Avoid consumption of alcohol as it may reduce the effectiveness of Pubnol-ET Tablet .

Uses of Pubnol-ET Tablet

Anxiety disorder.

Directions for Use

Swallow Pubnol-ET Tablet as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Pubnol-ET Tablet is a combination drug containing 'anti-anxiety medication', primarily used to treat anxiety disorder. It contains Etizolam (benzodiazepine) and Propanolol (a beta-blocker), used to treat anxiety. Etizolam works by increasing the action of a chemical messenger GABA, which suppresses the excessive and abnormal activity of nerve cells in the brain. Propanolol works by blocking a certain chemical messenger in the heart and blood vessels, reducing blood pressure, heart rate, and workload on the heart.

Storage

Keep Pubnol-ET Tablet out of the sight and reach of children.
Side effects of Pubnol-ET Tablet
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.
  • Reducing the amount of time you spend outside and indoors in the cold.
  • keeping your hands warm by donning mittens, gloves, or other protective clothing.
  • Observing a skincare regimen that safeguards your fingers and hands.
  • To improve circulation, give your hands and feet a little massage.
  • If you experience symptoms like colour change in the affected area, numbness, pain or tingling sensation after taking a medicine, inform your doctor and discuss about change in dose or alternative medicine.
  • Your doctor may prescribe calcium channel blockers like amlodipine or nifedipine to help relax blood vessels and enhance blood flow to the hands and feet.
  • Wear gloves, socks and warm clothes, especially in cold weather.
  • Spend less time in cold environments and avoid touching cold objects.
  • Practice relaxation methods like deep breathing to manage stress.
  • Quit smoking as nicotine constricts blood vessels worsening Raynaud’s symptoms.
  • Keep regular sleeping hours.
  • Don’t consume nicotine, caffeine, or alcohol in the hours leading up to bed.
  • Practice relaxation exercises before bedtime.
  • Regular physical activity can promote deeper and better sleep. However, avoid intense exercise within 2-3 hours of bedtime, as it can disrupt your sleep.
  • If nightmares continue, cognitive behavioral therapy (CBT) may be a helpful treatment option. Your doctor may recommend CBT to address underlying issues and provide coping strategies to manage nightmares.
  • Manage stress by practising deep breathing, yoga or meditation.
  • Participating in activities you enjoy, or exercising may also help manage agitation.
  • Get enough sleep. Maintain a regular sleep cycle.
  • Exercise regularly. Try physical activities like walking, running, or dancing.

Drug Warnings

Do not take Pubnol-ET Tablet if you are allergic to Pubnol-ET Tablet or any of its ingredients. If you are pregnant or breastfeeding, please inform your doctor before starting Pubnol-ET Tablet as it may cause adverse effects in the baby. Pubnol-ET Tablet should be used with caution in elderly patients as there is an increased risk of adverse reactions such as dizziness, muscle weakness, and drowsiness. Inform your doctor if you have myasthenia gravis (muscle weakness), chronic pulmonary insufficiency, drug addiction, kidney or liver problems before taking Pubnol-ET Tablet . Do not take Pubnol-ET Tablet with opioids as it may cause breathing problems, drowsiness, coma, and even death.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Pubnol-ET Tablet:
Coadministration of thioridazine with Pubnol-ET Tablet may increase the blood levels of thioridazine and cause an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is an interaction between Pubnol-ET Tablet and thioridazine, they can be taken together if prescribed by a doctor. However, if you experience sudden dizziness, lightheadedness, fainting, and shortness of breath contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Pubnol-ET Tablet:
Using Pubnol-ET Tablet together with terbutaline may reduce the benefits of both medications, since they have opposing effects in the body. In addition, Pubnol-ET Tablet can sometimes cause breathing problems.

How to manage the interaction:
Although taking Pubnol-ET Tablet together with Terbutaline can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
PropranololIndacaterol
Severe
How does the drug interact with Pubnol-ET Tablet:
Using Pubnol-ET Tablet together with indacaterol may reduce the benefits of both medications, since they have opposing effects in the body. In addition, Pubnol-ET Tablet can cause breathing problems.

How to manage the interaction:
Although taking Pubnol-ET Tablet together with Indacaterol can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
PropranololIobenguane (131i)
Severe
How does the drug interact with Pubnol-ET Tablet:
Coadministration of iobenguane (131i) and Pubnol-ET Tablet may interfere with the effects of iobenguane I-131 in treating your condition.

How to manage the interaction:
Although there is a possible interaction between Pubnol-ET Tablet and Iobenguane (131i), you can take these medicines together if prescribed by your doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
PropranololDolasetron
Severe
How does the drug interact with Pubnol-ET Tablet:
Taking Pubnol-ET Tablet and Dolasetron together can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although taking Pubnol-ET Tablet together with Dolasetron can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, consult your doctor if you experience lightheadedness, dizziness, fainting, or irregular heartbeat, consult your doctor immediately. Do not stop using any medications without consulting your doctor.
How does the drug interact with Pubnol-ET Tablet:
Using fingolimod with Pubnol-ET Tablet can cause an excessive lowering of heart rate and can lead to other heart problems.

How to manage the interaction:
Although taking Pubnol-ET Tablet together with Fingolimod can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, consult your doctor immediately if you experience lightheadedness, fainting, shortness of breath, chest pain, or heart palpitations. Do not stop using any medicines without consulting a doctor.
How does the drug interact with Pubnol-ET Tablet:
Taking Pubnol-ET Tablet with Labetalol can potentially enhance the effects of orthostatic hypotension (low blood pressure that happens when standing after sitting or lying down).

How to manage the interaction:
Although taking Pubnol-ET Tablet together with Labetalol can result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience lightheadedness or dizziness upon standing, blurred vision, weakness, fainting, or confusion. Do not discontinue any medicine without consulting a doctor.
How does the drug interact with Pubnol-ET Tablet:
Coadministration of Aminophylline with Pubnol-ET Tablet together can make Pubnol-ET Tablet less effective and increase the effects of aminophylline.

How to manage the interaction:
Taking Aminophylline with Pubnol-ET Tablet can cause an interaction. However, it can be taken only if a doctor has advised it. If you experience nausea, vomiting, sleeplessness, restlessness, irregular heartbeats, or difficulty in breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Pubnol-ET Tablet:
Co-administration of Epinephrine with Pubnol-ET Tablet may cause severe high blood pressure and reduced heart rate.

How to manage the interaction:
Taking Epinephrine with Pubnol-ET Tablet can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Pubnol-ET Tablet:
Taking atenolol and Pubnol-ET Tablet together may lower your blood pressure excessively which may lead to side effects.

How to manage the interaction:
Combined use of atenolol and Pubnol-ET Tablet may result in an interaction, it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Do regular exercise and maintain healthy body weight.
  • Maintain a diet rich in fruits, vegetables, and whole grains.
  • Avoid fried foods, high-fat dairy products, pastries, and processed foods as they may worsen anxiety.
  • Follow a regular sleep pattern. Do not take a nap during day time.
  • Avoid watching tv, using mobiles or laptops just before bedtime.
  • Avoid consumption of alcohol as it may increase drowsiness

Side Effects of Pubnol-ET Tablet

  • Confusion
  • Slow heart rate
  • Memory impairment
  • Tiredness
  • Nightmares
  • Cold extremities
  • Uncoordinated body movements
  • Drowsiness
  • Blurring of vision
  • Loss of appetite
  • Diarrhoea
  • Dry eyes
  • Mood swings

Habit Forming

Yes

Therapeutic Class

ANXIOLYTICS

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Pubnol-ET Tablet contains Etizolam (benzodiazepine) and Propanolol (a beta-blocker), used to treat anxiety. Etizolam works by increasing the action of a chemical messenger GABA, which suppresses the excessive and abnormal activity of nerve cells in the brain. Propanolol works by blocking a certain chemical messenger in the heart and blood vessels, reducing blood pressure, heart rate, and workload on the heart.

No, you are not recommended to stop taking Pubnol-ET Tablet without consulting your doctor as it may cause withdrawal symptoms such as palpitations (the sensation that the heart skipped a beat or extra beat), anxiety, confusion, difficulty in sleeping, and tremors. Therefore, take Pubnol-ET Tablet for as long as your doctor has prescribed it, and if you experience any difficulty while taking Pubnol-ET Tablet , please consult your doctor so that the dose may be gradually reduced.

No, you are not recommended to take Pubnol-ET Tablet with opioids as co-administration of these medicines may cause breathing problems, drowsiness, or other adverse effects. However, before using Pubnol-ET Tablet with any other medicines, you are advised to contact your doctor so that the dosage may be adjusted accordingly to use safely.

Yes, Pubnol-ET Tablet may cause mental or physical dependence if used for a prolonged time. Therefore, take Pubnol-ET Tablet only in dose and duration as advised by your doctor.

Quitting smoking, avoiding alcohol intake, and caffeine-containing food drinks can help you minimize the common side effect. If side effects like exhausted feeling, sleepiness (sedation), muscle weakness, and body posture imbalance persist, it means you need some blood test to find out the exact cause.

Drug-Drug Interactions Checker List

  • CLONIDINE
  • MOXONIDINE
  • LOFEXIDINE
  • HYDRALAZINE
  • MINOXIDIL
  • NITROPRUSSIDE
  • PHENYTOIN
  • CLONAZEPAM
  • ALPRAZOLAM
  • ESCITALOPRAM
  • CARBAMAZEPINE
  • PAROXETINE
  • FLUVOXAMINE
  • TRAZODONE
  • CETIRIZINE
  • BUPROPION
  • MORPHINE
  • CODEINE
  • CISAPRIDE
  • ZOLPIDEM
  • DIAZOXIDE
  • FLUCONAZOLE
  • CIMETIDINE
  • ESOMEPRAZOLE
  • OMEPRAZOLE
  • CLOZAPINE
  • DISULFIRAM

Special Advise

  • Do not take Pubnol-ET Tablet for a prolonged time as it may lead to mental or physical dependence on Pubnol-ET Tablet .
  • Pubnol-ET Tablet causes drowsiness. Avoid doing activities that require your complete focus and attention, like driving when on this drug.
  • An abrupt stoppage of Pubnol-ET Tablet can lead to significant withdrawal symptoms. Always discuss with your doctor about decreasing the dosage before completely stopping its usage.
  • Avoid consuming alcohol while on Pubnol-ET Tablet  as it can lead to dangerous side effects.
  • Pubnol-ET Tablet is unsafe for usage if you're pregnant or are planning to get pregnant. Discuss with your doctor in such situations about changing/replacing the medicine with safer alternatives.
  • To avoid getting addicted to this drug, take it only in prescribed quantities and only as directed by your doctor. Do not self-medicate.

Disease/Condition Glossary

Anxiety: High levels of anxiety can cause panic attacks, with intense feelings of nervousness, fear, and sudden onset of sweating, hyperventilation, fast heartbeat, and flushing of the skin. Anxiety disorders are different from feelings of anxiety and feeling nervous, which involve excessive anxiety, fear, or worry. Fear can arise due to anxiety and emotional response to an immediate threat related to more staying to fight or leaving to escape danger. Fear before getting ready for surgery is also a part of short-term anxiety. Anxiety disorders can affect an individual’s job performance, school work, and personal relationships.

Have a query?

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Alcohol

Caution

Avoid consumption of alcohol with Pubnol-ET Tablet as it may increase the risk of drowsiness and other adverse effects.

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Pregnancy

Caution

Pubnol-ET Tablet is a Category C pregnancy drug, and safety is unknown. Please consult your doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Caution

It is unknown whether Pubnol-ET Tablet is excreted in human milk. Please consult a doctor before using Pubnol-ET Tablet while breastfeeding.

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Driving

Caution

Pubnol-ET Tablet may cause dizziness, double vision, or drowsiness in some people. Therefore, avoid driving if you feel drowsy, dizzy, or experience any vision problems after taking Pubnol-ET Tablet .

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Liver

Caution

Take Pubnol-ET Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Pubnol-ET Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

The safety of Pubnol-ET Tablet in children is unknown. Please consult a doctor for more information.

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