UTERGIN 0.125MG TABLET

Written By Santoshini Reddy G , M Pharmacy

Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

MRP ₹86.8

(Inclusive of all Taxes)

₹13.0 Cashback (15%)

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Non returnable*

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Prescription drug

Whats That

About UTERGIN 0.125MG TABLET

UTERGIN 0.125MG TABLET belongs to the class of medication called semi-synthetic ergot alkaloids used to prevent and control postpartum haemorrhage. It is used after delivery for the routine management of uterine atony, subinvolution of the uterus, and haemorrhage.

UTERGIN 0.125MG TABLET contains Methylergometrine which works by increasing the smooth muscle contractions of the uterus. This helps compress the blood vessels and controls bleeding after delivery.

Take UTERGIN 0.125MG TABLET exactly as prescribed by the doctor. In some cases, UTERGIN 0.125MG TABLET may cause high blood pressure associated with seizures and/or headache, nausea, and vomiting. If the side effects persist or worsen, consult your doctor.

Do not take UTERGIN 0.125MG TABLET if you are pregnant. Consult your doctor if you are breastfeeding. UTERGIN 0.125MG TABLET is not recommended for children as safety and effectiveness have not been established. Keep your doctor informed about your health condition and medications to rule out any interactions/side effects.

Uses of UTERGIN 0.125MG TABLET

Postpartum haemorrhage

Directions for Use

Swallow UTERGIN 0.125MG TABLET as a whole with water; do not crush, break or chew it.

Medicinal Benefits

UTERGIN 0.125MG TABLET is indicated in the prevention and control of postpartum haemorrhage. It is used following delivery of the placenta for the routine management of uterine atony (soft and weak uterus after childbirth), subinvolution of the uterus, and haemorrhage. UTERGIN 0.125MG TABLET contains Methylergometrine, a semi-synthetic ergot alkaloid which works by increasing the smooth muscle contractions of the uterus. This helps compress the blood vessels and controls bleeding after delivery.

Storage

Keep UTERGIN 0.125MG TABLET out of reach and sight of children.

Side effects of Utergin 0.125mg Tablet

Fits

Stress levels should be managed by practicing yoga and meditation regularly.
Maintain a proper sleeping schedule.
Maintain a balanced diet containing low glycemic index like fruits, vegetables, proteins and grains.
Do not consume alcohol.

Headache

Dealing with Medication-Induced Headache:

Hydrate your body: Drink enough water to prevent dehydration and headaches.
Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
Take rest: lie down in a quiet, dark environment.
Cold or warm compresses can help reduce tension.
Stay Upright: Maintain good posture to keep symptoms from getting worse.
To treat headaches naturally, try acupuncture or massage therapy.
Over-the-counter pain relievers include acetaminophen and ibuprofen.
Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
Frequent Headaches: If you get reoccurring headaches, consult your doctor.
Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Drug Warnings

Do not take UTERGIN 0.125MG TABLET if you are allergic to any of its components, if you have high blood pressure, toxaemia (a complication of pregnancy characterised by high blood pressure), or if you are pregnant. Inform your doctor if you have coronary artery disease, sepsis, vascular disease, or liver or kidney impairment. Consult your doctor if you are breastfeeding. The safety and effectiveness of UTERGIN 0.125MG TABLET in children have not been established. Let your doctor know if you are taking prescription/non-prescription medicines, including herbal products and supplements.

Drug-Drug Interactions

MethylergometrineItraconazole

Critical

MethylergometrineSumatriptan

Critical

Drug-Drug Interactions

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MethylergometrineItraconazole

Critical

How does the drug interact with Utergin 0.125mg Tablet:
Co-administration of Utergin 0.125mg Tablet and Itraconazole may increase the blood levels of Utergin 0.125mg Tablet.

How to manage the interaction:
Utergin 0.125mg Tablet and itraconazole may interact, but if prescribed by a doctor, they can be used together. Do not discontinue any medications without first consulting your doctor.

MethylergometrineSumatriptan

Critical

How does the drug interact with Utergin 0.125mg Tablet:
Coadministration of Sumatriptan with Utergin 0.125mg Tablet can reduce the blood flow and increase the risk of high blood pressure or heart-related problems.

How to manage the interaction:
Taking Sumatriptan with Utergin 0.125mg Tablet together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.

MethylergometrineGlyceryl trinitrate

Critical

How does the drug interact with Utergin 0.125mg Tablet:
Coadministration of Utergin 0.125mg Tablet with Glyceryl trinitrate can increase the levels and side effects of Utergin 0.125mg Tablet.

How to manage the interaction:
Taking Utergin 0.125mg Tablet with Glyceryl trinitrate is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, headache, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor. Do not discontinue any medications without first consulting your doctor.

MethylergometrineClarithromycin

Critical

How does the drug interact with Utergin 0.125mg Tablet:
When Utergin 0.125mg Tablet is taken with Clarithromycin, the amount of Utergin 0.125mg Tablet in the blood can go up. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Clarithromycin with Utergin 0.125mg Tablet is generally avoided as it can lead to an interaction, it can be taken only when advised by a doctor. Do not stop using any medications without a doctor's advice.

MethylergometrineVoriconazole

Critical

How does the drug interact with Utergin 0.125mg Tablet:
Coadministration of Utergin 0.125mg Tablet with Voriconazole may increase the blood level of Utergin 0.125mg Tablet.

How to manage the interaction:
Although Utergin 0.125mg Tablet with Voriconazole can cause an interaction, they can be taken if prescribed by a doctor. Do not discontinue any medication without consulting a doctor.

MethylergometrineRitonavir

Critical

How does the drug interact with Utergin 0.125mg Tablet:
Taking Utergin 0.125mg Tablet with Ritonavir can significantly increase the blood levels and effects of Utergin 0.125mg Tablet.

How to manage the interaction:
Taking Utergin 0.125mg Tablet with Ritonavir is not recommended, but can be taken together if prescribed by a doctor. In case you experience any side effects like severe abdominal discomfort, nausea, vomiting, tingling or numbness, weakness or pain in the muscles, pale skin, blue or purple discoloration on fingers or toes, tightness or pain in the chest, irregular heartbeat, intense headache, breathing difficulties, confusion, or slurred speech, consult a doctor. Do not discontinue any medications without consulting a doctor.

MethylergometrineKetoconazole

Critical

How does the drug interact with Utergin 0.125mg Tablet:
Using Ketoconazole with Utergin 0.125mg Tablet can increase the concentration of Utergin 0.125mg Tablet, which may lead to side effects.

How to manage the interaction:
Taking Ketoconazole with Utergin 0.125mg Tablet is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. Do not discontinue any medication without consulting a doctor.

MethylergometrinePhenylephrine

Severe

How does the drug interact with Utergin 0.125mg Tablet:
Taking Phenylephrine with Utergin 0.125mg Tablet can led to side effects like increased blood pressure.

How to manage the interaction:
Taking Phenylephrine with Utergin 0.125mg Tablet can lead to an interaction but can be taken if prescribed by the doctor. It is advised to monitor your blood pressure regularly. Do not discontinue any medications without a doctor's advice.

MethylergometrineEphedrine

Severe

How does the drug interact with Utergin 0.125mg Tablet:
Taking Ephedrine with Utergin 0.125mg Tablet may lead to an increase in the risk of high blood pressure.

How to manage the interaction:
Although taking Ephedrine with Utergin 0.125mg Tablet may lead to an interaction, it can be taken if prescribed by the doctor. It is advised to maintain your blood pressure. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

METHYLERGOMETRINE-0.125MGGrapefruit and Grapefruit Juice

Moderate

Drug-Food Interactions

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METHYLERGOMETRINE-0.125MGGrapefruit and Grapefruit Juice

Moderate

Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consumption of Utergin 0.125mg Tablet with Grapefruit and Grapefruit may lead to an increase in the effectiveness of Utergin 0.125mg Tablet. Avoid or limit grapefruit and grapefruit juice consumption with Utergin 0.125mg Tablet. This can increase the risk or severity of side effects.

Diet & Lifestyle Advise

Include high-fibre foods such as fruits and whole grains.
Drink plenty of fluids such as water, fruit juices, and milk.
Limit processed/packaged foods, high salt/sugary foods and saturated fats.
Get plenty of rest.
Eat healthy meals and exercise appropriately.

Side Effects of UTERGIN 0.125MG TABLET

Hypertension (high blood pressure) associated with seizures and/or headache
Nausea
Vomiting

Habit Forming

No

Therapeutic Class

MISCELLANEOUS

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Author Details

Written By

Santoshini Reddy G

M Pharmacy

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 8, 2025 | 9:46 AM IST

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Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

How does UTERGIN 0.125MG TABLET work?

UTERGIN 0.125MG TABLET works by increasing the smooth muscle contractions of the uterus. This helps compress the blood vessels and controls bleeding after delivery.

Is UTERGIN 0.125MG TABLET safe for people with high blood pressure?

UTERGIN 0.125MG TABLET is not recommended for use in people with high blood pressure. Consult your doctor if you have hypertension.

Does UTERGIN 0.125MG TABLET cause nausea?

UTERGIN 0.125MG TABLET may cause nausea or vomiting as a side effect. It is not necessary for everyone taking UTERGIN 0.125MG TABLET to experience this side effect. However, if the condition persists or worsens, consult your doctor.

Is UTERGIN 0.125MG TABLET used in the management of uterine atony?

UTERGIN 0.125MG TABLET may be indicated in the management of uterine atony. Uterine atony refers to a weak and soft uterus after childbirth.

Drug-Drug Interactions Checker List

DIHYDROERGOTAMINE
ERGOTAMINE
ERYTHROMYCIN
TROLEANDOMYCIN
CLARITHROMYCIN
RITONAVIR
INDINAVIR
NELFINAVIR
DELAVIRDINE
KETOCONAZOLE
ITRACONAZOLE
VORICONAZOLE

Special Advise

Disease/Condition Glossary

Postpartum haemorrhage: It is a condition in which excessive bleeding occurs following childbirth. This can lead to a drop in blood pressure. Symptoms include vaginal bleeding that does not stop. Loss of tone in uterine muscles and bleeding disorder could be the causes of postpartum haemorrhage.