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  3. Zeparin 25000 Injection 5 ml

Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Non returnable*
COD available

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Composition :

HEPARIN-5000IU

Manufacturer/Marketer :

Zyphar's Pharmaceuticals Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

About Zeparin 25000 Injection 5 ml

Zeparin 25000 Injection 5 ml belongs to a class of drugs called anticoagulants or blood thinners. Zeparin 25000 Injection 5 ml is primarily used to prevent and treat deep vein thrombosis (blood clots in leg veins), pulmonary embolism (blood clots in the lung), stroke, Transient ischaemic attack (TIA), and heart attacks.  Deep vein thrombosis is a medical condition in which blood clots form in deep veins usually in the legs. Pulmonary embolism is a condition in which a blood clot blocks the arteries in the lungs. A stroke is a condition where a blood clot restricts the flow of blood to your brain, causing brain cells to die and possibly resulting in permanent brain damage or death. Transient ischaemic attack (TIA) is a condition also called 'mini-strokes', these have similar symptoms to a stroke, but the effects usually last less than 24 hours. Heart attack is a condition where a blood clot blocks a blood vessel supplying your heart, starving it of oxygen and causing chest pain and sometimes death.

Blood clots are formed to stop bleeding that occurs due to tissue injury. Though blood clots are useful to stop bleeding, they may be harmful when abnormally formed within blood vessels as they block blood vessels and inhibit blood flow to essential organs such as the brain, heart, or lungs. Zeparin 25000 Injection 5 ml works by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot) preventing blood clot formation.

Zeparin 25000 Injection 5 ml will be administered by a healthcare professional; do not self-administer. Some people may experience hemorrhage, thrombocytopenia (low platelets), hypersensitivity reactions, and elevations of liver enzyme (aminotransferase) levels. Most of these side effects of Zeparin 25000 Injection 5 ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Zeparin 25000 Injection 5 ml or any other medicines, please tell your doctor. It is not known whether Zeparin 25000 Injection 5 ml harms the baby or passes into breast milk in pregnancy and breastfeeding state. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Zeparin 25000 Injection 5 ml. Zeparin 25000 Injection 5 ml is not recommended for children below 2 months of age. If you have diabetes, kidney or liver problems, bleeding problems, or are aged above 60 years, inform your doctor before taking Zeparin 25000 Injection 5 ml.

Uses of Zeparin 25000 Injection 5 ml

Prevention of blood clots.

Directions for Use

Zeparin 25000 Injection 5 ml will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Zeparin 25000 Injection 5 ml is primarily used to prevent and treat blood clots by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot). Zeparin 25000 Injection 5 ml also reduces the risk of blood clots during surgeries (like heart surgery). Zeparin 25000 Injection 5 ml is used as an anticoagulant in blood transfusion and in a dialysis procedure.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Use Zeparin 25000 Injection 5 ml cautiously in conditions with increased risk of bleeding. Use of name contraindicated in patients with HIT - Heparin-induced thrombosis (the abnormal formation of blood clots inside a blood vessel) and HITT (heparin-induced thrombocytopenia and thrombosis) might occur. Monitoring of blood coagulation tests like platelet count and haematocrit should be done in all patients receiving Zeparin 25000 Injection 5 ml. Patients should inform the doctor that they are receiving Zeparin 25000 Injection 5 ml before any surgery is scheduled.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Zeparin 25000 Injection 5 ml:
Taking Tenecteplase with Zeparin 25000 Injection 5 ml can increase the risk of bleeding.

How to manage the interaction:
Taking Zeparin 25000 Injection 5 ml with Tenecteplase is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you notice unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Zeparin 25000 Injection 5 ml:
Taking Mifepristone with Zeparin 25000 Injection 5 ml can increase the risk of negative side effects.

How to manage the interaction:
Taking Zeparin 25000 Injection 5 ml with Mifepristone is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
HeparinBazedoxifene
Critical
How does the drug interact with Zeparin 25000 Injection 5 ml:
When Zeparin 25000 Injection 5 ml is taken with bazedoxifene the effects of Zeparin 25000 Injection 5 ml are reduced by bazedoxifene.

How to manage the interaction:
Taking Bazedoxifene with Zeparin 25000 Injection 5 ml is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Zeparin 25000 Injection 5 ml:
Taking Ticlopidine with Zeparin 25000 Injection 5 ml can increase the risk of bleeding.

How to manage the interaction:
Taking Ticlopidine with Zeparin 25000 Injection 5 ml is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Zeparin 25000 Injection 5 ml:
Taking Alteplase with Zeparin 25000 Injection 5 ml can increase the risk of bleeding.

How to manage the interaction:
Taking Zeparin 25000 Injection 5 ml with Alteplase is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you have unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
HeparinOritavancin
Critical
How does the drug interact with Zeparin 25000 Injection 5 ml:
Using Zeparin 25000 Injection 5 ml with Oritavancin can make Zeparin 25000 Injection 5 ml less effective as a therapy.

How to manage the interaction:
Zeparin 25000 Injection 5 ml is not recommended within 120 hours (5 days) of taking oritavancin. Oritavancin can interfere with certain of the major coagulation tests used to assess Zeparin 25000 Injection 5 ml's effectiveness and safety, it can be taken only if prescribed by a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Zeparin 25000 Injection 5 ml:
Taking Dasatinib with Zeparin 25000 Injection 5 ml can increase the risk and severity of bleeding.

How to manage the interaction:
Although there is a possible interaction between Zeparin 25000 Injection 5 ml and Dasatinib, you can take these medicines together if prescribed by a doctor. However, consult a doctor, if you experience bruising, dizziness, red or black, tarry stools, severe headache, and weakness. Do not stop using any medications without a doctor's advice.
How does the drug interact with Zeparin 25000 Injection 5 ml:
Coadministration of Ketorolac with Zeparin 25000 Injection 5 ml can increase the risk of bleeding.

How to manage the interaction:
There may be a possibility of interaction between Ketorolac and Zeparin 25000 Injection 5 ml, but it can be taken if prescribed by a doctor. However, if you experience any unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, call a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Zeparin 25000 Injection 5 ml:
Co-administration of Cangrelor with Zeparin 25000 Injection 5 ml can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Although there is a possible interaction between Zeparin 25000 Injection 5 ml and Cangrelor, you can take these medicines together if prescribed by a doctor. However, if you have any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, you should seek immediate medical attention. Do not stop using any medications without a doctor's advice.
How does the drug interact with Zeparin 25000 Injection 5 ml:
Taking Zeparin 25000 Injection 5 ml with Streptokinase can increase the risk of bleeding.

How to manage the interaction:
Although taking Zeparin 25000 Injection 5 ml and Streptokinase together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience any unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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HEPARIN-5000IUHerbal products/medicines
Moderate

Drug-Food Interactions

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HEPARIN-5000IUHerbal products/medicines
Moderate
Common Foods to Avoid:
Garlic Pill

How to manage the interaction:
Taking Zeparin 25000 Injection 5 ml along with herbs and supplements such as garlic, ginger, bilberry, danshen, piracetam, and ginkgo biloba can lead to an increased risk of bleeding Avoid taking herbs and supplements such as garlic, ginger, bilberry, danshen, piracetam, and ginkgo biloba while taking Zeparin 25000 Injection 5 ml.

Habit Forming

No

Therapeutic Class

ANTICOAGULANTS / ANTITHROMBOTICS. ANTICONVULSANTS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Drug-Drug Interactions Checker List

  • SALICYLIC ACID
  • IBUPROFEN
  • INDOMETHACIN
  • PHENYLBUTAZONE
  • CELECOXIB
  • HYDROXYCHLOROQUINE
  • ABCIXIMAB
  • DIPYRIDAMOLE
  • DIGITALIS
  • TETRACYCLINE
  • NITROGLYCERIN

Special Advise

Regular blood tests are advised while taking Zeparin 25000 Injection 5 ml to monitor prothrombin, platelets and coagulation time on regular basis.

Disease/Condition Glossary

Deep vein thrombosis (blood clots in legs) is a medical condition in which blood clots form in deep veins usually in the legs. The symptoms include leg pain or swelling.

Pulmonary embolism (blood clots in the lung) is a condition that occurs as the blood clots break and travel to the lungs from deep veins in the legs or other parts of the body. The symptoms of pulmonary embolism include chest pain, cough, and shortness of breath. 

Stroke is a condition where a blood clot restricts the flow of blood to your brain, causing brain cells to die and possibly resulting in permanent brain damage or death.

Transient ischaemic attack (TIA) is a condition also called 'mini-strokes', these have similar symptoms to a stroke, but the effects usually last less than 24 hours.

Heart attack is a condition where a blood clot blocks a blood vessel supplying your heart, starving it of oxygen and causing chest pain and sometimes death. Quick medication is advised to reduce the risk of serious conditions due to blood clots.

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