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About Lefuhans-20 Tablet
Lefuhans-20 Tablet belongs to the group of medicines called 'anti-rheumatic agents' used to relieve symptoms of rheumatoid arthritis and psoriatic arthritis. Rheumatoid arthritis is an auto-immune disease (the body's immune system attacks its tissue) which leads to joint pain and damage. Psoriatic arthritis is a kind of inflammatory arthritis which occurs in patients with psoriasis (red patches of skin with silvery scales).
Lefuhans-20 Tablet contains 'Leflunomide' an isoxazole immunomodulatory agent which works by blocking the formation of genetic material, i.e. DNA required for survival of replicating (dividing) cells of the immune system. As a result, it suppresses the activated immune system to reduce pain, inflammation and swelling.
Take Lefuhans-20 Tablet at the same time every day as prescribed by your doctor. In some cases, Lefuhans-20 Tablet may cause common side-effects such as diarrhoea, nausea, stomach pain, indigestion, rash, and hair loss. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
Do not take Lefuhans-20 Tablet if you are pregnant or planning for pregnancy as Lefuhans-20 Tablet may cause serious congenital disabilities. Lefuhans-20 Tablet should not be taken by breastfeeding mothers as it passes into breast milk. Lefuhans-20 Tablet may cause dizziness, so drive with caution. Avoid consuming alcohol along with Lefuhans-20 Tablet as it could lead to increased dizziness and liver damage. Lefuhans-20 Tablet may make you more susceptible to infections; consult your doctor if you develop any signs of infections such as fever, sore throat, breathlessness, jaundice, unexplained bleeding or bruising.
Uses of Lefuhans-20 Tablet
Directions for Use
Medicinal Benefits
Lefuhans-20 Tablet belongs to the group of medicines called anti-rheumatic agents used to relieve symptoms of rheumatoid arthritis and psoriatic arthritis. Lefuhans-20 Tablet is a disease-modifying antirheumatic drug (DMARDs) which inhibits an enzyme called dihydroorotate dehydrogenase and has antiproliferative activity (suppresses the cell growth). Thereby, helps in treating inflammation, redness, and swelling.
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Side Effects of Lefuhans-20 Tablet
Drug Warnings
Do not take Lefuhans-20 Tablet if you are allergic to leflunomide, have severe liverkidney problems, low levels of protein in the blood, immune system problems, bone marrow problems, or serious infections. Lefuhans-20 Tablet is not recommended to be used in pregnant women, lactating mothers and people below 18 years of age. Talk to your doctor before taking Lefuhans-20 Tablet if you have/had serious infections like interstitial lung disease (inflammation of lungs), tuberculosis (TB), or pneumonia. Lefuhans-20 Tablet may cause dizziness, so drive with caution. Lefuhans-20 Tablet may make you more susceptible to infections; notify the doctor if you develop infections, sore throat, breathlessness, jaundice, unexplained bleeding or bruising.
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Lefuhans-20 Tablet is a disease-modifying antirheumatic drug (DMARD) which stops DNA (genetic material) of the provoked immune system cells required for its survival. Thereby, helps in treating inflammation, redness, and swelling at the damaged site (especially joint).
Lefuhans-20 Tablet may cause diarrhoea. Drink plenty of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea consult your doctor. Do not take anti-diarrheal medicine on your own.
It might take 4-6 weeks before you notice any benefit. In some cases, it might also take 6 months for you to feel the full effect of Lefuhans-20 Tablet . Take Lefuhans-20 Tablet for as long as your doctor has prescribed to treat your condition effectually.
Inform your doctor if you have liver disease, kidney disease, weak immune system and serious infections like pneumonia, or tuberculosis (TB).
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Special Advise
Regular blood tests to monitor your liver function after starting Lefuhans-20 Tablet , and for every 6-8 weeks are advised.
Disease/Condition Glossary
Rheumatoid arthritis: It is an auto-immune disease (where the body's immune system attacks its tissue) which leads to joint pain and damage. Symptoms of rheumatoid arthritis include pain, inflammation of joints, difficulty in moving and swelling. Patients with rheumatoid arthritis have intense joint pain (especially knee joint) with stiffness.
Psoriatic arthritis: Psoriatic arthritis is an autoimmune disease characterized by inflammation of the skin (psoriasis) and joints (inflammatory arthritis). It mainly affects large joints in the lower extremities, distal joints of toes and fingers, back and pelvis. Symptoms include inflammation of joints, difficulty moving, swelling, patches of red, scaly skin and pain.