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Written By Divya L , PharmaD
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

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Whats That

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Composition :

FLUPHENAZINE-25MG

Manufacturer/Marketer :

Mova Pharmaceutical Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Monazine 25 mg Injection

Monazine 25 mg Injection belongs to a group of medicines called 'antipsychotics/neuroleptics,' primarily used to treat psychotic disorders like schizophrenia. Schizophrenia is a mental condition in which the person may feel, hear or see things that are not there (hallucinations), believe things that are not true, and feel unusually suspicious or confused. 

Monazine 25 mg Injection contains 'Fluphenazine' that belongs to the class of phenothiazines. It works by affecting the balance of the neurotransmitters in the brain. Thereby, Monazine 25 mg Injection decreases psychotic symptoms like hallucinations, delusions, and hostility (unfriendly or opposed behaviour) associated with schizophrenia. Monazine 25 mg Injection is intended for use in the management of patients requiring prolonged parenteral antipsychotic therapy.

Your doctor will decide the dose and duration based on your medical condition and response to treatment. Common side effects of Monazine 25 mg Injection include lethargy/tiredness, drowsiness, headache, dizziness, blurred vision, nausea, loss of appetite, dry mouth, constipation, stuffy nose, sweating, weight changes, and pain/redness/swelling at the injection site. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Monazine 25 mg Injection is not recommended for treatment in patients with dementia-related psychosis. Inform your doctor before starting Monazine 25 mg Injection if you have a history of liver/kidney/heart diseases, breathing problems, blood cell disorder, Parkinson's disease, glaucoma, breast cancer, depression, or fits. If you are pregnant, planning to conceive, or a breastfeeding mother, inform your doctor before starting Monazine 25 mg Injection. Avoid consuming alcohol while being treated with Monazine 25 mg Injection as it can make you dizzy or drowsy. Do not drive or operate machinery since it can make you sleepy and interfere with your driving ability. Monazine 25 mg Injection is not approved for children younger than 12 years of age.

Uses of Monazine 25 mg Injection

Schizophrenia.

Directions for Use

It will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Monazine 25 mg Injection is used to treat schizophrenia and associated psychotic symptoms. It contains 'Fluphenazine' that affects the balance of the neurotransmitters in the brain. It helps clear thinking and relieves psychotic symptoms like delusions, hostility, and hallucinations in schizophrenia.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Monazine 25 mg Injection is not recommended for treatment in patients with dementia-related psychosis. Before using Monazine 25 mg Injection, let your doctor know if you have a medical history of liver or kidney diseases, heart problems, breathing problems (asthma), pheochromocytoma, fits, glaucoma, blood problems (leukopenia, thrombocytopenia), Parkinson's disease, low blood calcium levels, enlarged prostate, depression, or breast cancer. Please consult your doctor if you are pregnant, planning to conceive or a breastfeeding mother before starting Monazine 25 mg Injection. Avoid consuming alcohol during the treatment, as it might lead to increased dizziness and drowsiness. Avoid driving or operating machinery, as this medicine may decrease your mental alertness, making you feel dizzy or drowsy. Monazine 25 mg Injection is not recommended for children below 12 years of age as safety and effectiveness have not been established.

Drug-Drug Interactions

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FluphenazineHaloperidol
Critical
FluphenazineZiprasidone
Critical

Drug-Drug Interactions

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FluphenazineHaloperidol
Critical
How does the drug interact with Monazine 25 mg Injection:
Coadministration of Monazine 25 mg Injection and Haloperidol can increase the risk of developing irregular heart rhythms.

How to manage the interaction:
Taking Monazine 25 mg Injection and Haloperidol together is generally avoided as it can lead to an interaction, but it can be taken when a doctor advises. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
FluphenazineZiprasidone
Critical
How does the drug interact with Monazine 25 mg Injection:
Taking ziprasidone with Monazine 25 mg Injection can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Ziprasidone with Monazine 25 mg Injection is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
FluphenazineChloroquine
Severe
How does the drug interact with Monazine 25 mg Injection:
Using chloroquine together with Monazine 25 mg Injection can increase the risk of an irregular heart rhythm

How to manage the interaction:
Taking chloroquine and Monazine 25 mg Injection together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
FluphenazinePropylthiouracil
Severe
How does the drug interact with Monazine 25 mg Injection:
Coadministration of Monazine 25 mg Injection with Propylthiouracil can increase the risk of developing infections.

How to manage the interaction:
Co-administration of Propylthiouracil with Monazine 25 mg Injection can possibly result in an interaction, but it can be taken if your doctor has advised it. However, contact a doctor if you experience any symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, or burning urination. Do not discontinue any medications without first consulting your doctor.
FluphenazineEfavirenz
Severe
How does the drug interact with Monazine 25 mg Injection:
Taking Monazine 25 mg Injection and Efavirenz can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Monazine 25 mg Injection and Efavirenz together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
FluphenazineMorphine
Severe
How does the drug interact with Monazine 25 mg Injection:
Taking Morphine with Monazine 25 mg Injection may increase the risk of central nervous system depression, which can lead to breathing difficulty and unconsciousness.

How to manage the interaction:
Coadministration of Morphine and Monazine 25 mg Injection together can cause an interaction, it can be taken if a doctor has suggested it. However, if you notice any symptoms like dizziness, drowsiness, difficulty concentrating, impaired judgment, reaction speed, and motor coordination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
FluphenazineEscitalopram
Severe
How does the drug interact with Monazine 25 mg Injection:
Combining Monazine 25 mg Injection with Escitalopram can increase the risk of adverse effects.

How to manage the interaction:
Taking Escitalopram with Monazine 25 mg Injection together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these symptoms - dizziness, feeling lightheaded or faint, heart palpitations, irregular heart rhythm, difficulty breathing, a heart condition, or severe and prolonged diarrhea or vomiting, contact your doctor right away. Do not stop using any medications without talking to your doctor.
FluphenazineCeritinib
Severe
How does the drug interact with Monazine 25 mg Injection:
Taking Ceritinib together with Monazine 25 mg Injection can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is a interaction between Ceritinib and Monazine 25 mg Injection, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without consulting doctor.
FluphenazineGatifloxacin
Severe
How does the drug interact with Monazine 25 mg Injection:
Taking Gatifloxacin and Monazine 25 mg Injection can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Gatifloxacin and Monazine 25 mg Injection together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
FluphenazineMethimazole
Severe
How does the drug interact with Monazine 25 mg Injection:
Co-administration of Monazine 25 mg Injection and Methimazole together can cause the risk of neutropenia leading to serious infections.

How to manage the interaction:
Although there is a possible interaction between Methimazole and Monazine 25 mg Injection, you can take these medicines together if prescribed by a doctor. If you notice any of these signs - fever, chills, body aches, sore throat, coughing, breathing difficulties, mouth ulcers, or flu-like symptoms - contact a doctor right away. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain proper weight by following a healthy diet.
  • Exercise regularly as it helps in less cognitive decline and brain volume loss.
  • Avoid smoking and alcohol consumption.
  • Try to avoid stress by practising meditation or yoga.
  • Include fruits and vegetables in your diet as they contain antioxidants.
  • Eat nutritious food as it helps in cognitive stimulation.
  • Limit foods with high cholesterol and saturated fats.
  • Cut down on sugar, salt and processed foods.
  • Drink plenty of water.
  • Follow a regular sleep pattern.

Habit Forming

No

Therapeutic Class

ANTIPSYCHOTICS

Monazine 25 mg Injection Substitute

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Monazine 25 mg Injection contains 'Fluphenazine,' an antipsychotic medication that affects the balance of neurotransmitters in the brain, thus improving mood, behaviour, and thoughts in schizophrenia.

Before using Monazine 25 mg Injection, let your doctor know if you have a medical history of liver or kidney diseases, heart problems (history of stroke), breathing problems (asthma, emphysema), pheochromocytoma (adrenal gland tumour), Parkinson's disease, fits, low white blood cells, glaucoma, blood problems (leukopenia, thrombocytopenia), low blood calcium levels, enlarged prostate, breast cancer, and Reye's syndrome (a rare, but serious condition that causes swelling in the brain and liver damage). Please let your doctor know if you have any other medical problems before starting Monazine 25 mg Injection.

Monazine 25 mg Injection is not recommended for older dementia patients since it can lead to serious side effects like heart failure, fast/irregular heartbeat, and pneumonia. However, please discuss with the doctor possibly safer treatments for dementia-related behaviour problems.

Monazine 25 mg Injection may cause dizziness. It is advised to avoid getting up too fast from a sitting or lying position that can make you feel dizzy.

Dry mouth could be a side-effect of Monazine 25 mg Injection. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help stimulate saliva and prevent drying of the mouth.

Drug-Drug Interactions Checker List

  • CLONIDINE
  • CODEINE
  • HYDROCODONE
  • ALPRAZOLAM
  • LORAZEPAM
  • CARISOPRODOL
  • CYCLOBENZAPRINE
  • CETIRIZINE
  • DIPHENHYDRAMINE
  • LITHIUM
  • QUINIDINE

Special Advise

This medicine may interfere with tests for pregnancy and phenylketonuria and some urine tests. Let your doctor or laboratory staff know you are taking Monazine 25 mg Injection if you undergo other medical examinations.

Disease/Condition Glossary

Schizophrenia: It is a condition in which the person may see, hear or feel things that are not there, believe things that are not true, or feel unusually suspicious or confused. Symptoms include hallucinations, delusions, thought disorders, movement disorders, disorganised thinking, loss of interest, lack of emotions, etc. Schizophrenia is triggered by physical, genetic, psychological, and environmental factors. Patients suffering from this disease may require lifelong treatment. Treatment involves a combination of medications, psychotherapy and care services.

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