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Written By Divya L , PharmaD
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

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Composition :

FLUPHENAZINE-25MG

Manufacturer/Marketer :

Ikon Pharmachem

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

About Sizonorm Injection 1 ml

Sizonorm Injection 1 ml belongs to a group of medicines called 'antipsychotics/neuroleptics,' primarily used to treat psychotic disorders like schizophrenia. Schizophrenia is a mental condition in which the person may feel, hear or see things that are not there (hallucinations), believe things that are not true, and feel unusually suspicious or confused. 

Sizonorm Injection 1 ml contains 'Fluphenazine' that belongs to the class of phenothiazines. It works by affecting the balance of the neurotransmitters in the brain. Thereby, Sizonorm Injection 1 ml decreases psychotic symptoms like hallucinations, delusions, and hostility (unfriendly or opposed behaviour) associated with schizophrenia. Sizonorm Injection 1 ml is intended for use in the management of patients requiring prolonged parenteral antipsychotic therapy.

Your doctor will decide the dose and duration based on your medical condition and response to treatment. Common side effects of Sizonorm Injection 1 ml include lethargy/tiredness, drowsiness, headache, dizziness, blurred vision, nausea, loss of appetite, dry mouth, constipation, stuffy nose, sweating, weight changes, and pain/redness/swelling at the injection site. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Sizonorm Injection 1 ml is not recommended for treatment in patients with dementia-related psychosis. Inform your doctor before starting Sizonorm Injection 1 ml if you have a history of liver/kidney/heart diseases, breathing problems, blood cell disorder, Parkinson's disease, glaucoma, breast cancer, depression, or fits. If you are pregnant, planning to conceive, or a breastfeeding mother, inform your doctor before starting Sizonorm Injection 1 ml. Avoid consuming alcohol while being treated with Sizonorm Injection 1 ml as it can make you dizzy or drowsy. Do not drive or operate machinery since it can make you sleepy and interfere with your driving ability. Sizonorm Injection 1 ml is not approved for children younger than 12 years of age.

Uses of Sizonorm Injection 1 ml

Schizophrenia.

Directions for Use

It will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Sizonorm Injection 1 ml is used to treat schizophrenia and associated psychotic symptoms. It contains 'Fluphenazine' that affects the balance of the neurotransmitters in the brain. It helps clear thinking and relieves psychotic symptoms like delusions, hostility, and hallucinations in schizophrenia.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Sizonorm Injection 1 ml is not recommended for treatment in patients with dementia-related psychosis. Before using Sizonorm Injection 1 ml, let your doctor know if you have a medical history of liver or kidney diseases, heart problems, breathing problems (asthma), pheochromocytoma, fits, glaucoma, blood problems (leukopenia, thrombocytopenia), Parkinson's disease, low blood calcium levels, enlarged prostate, depression, or breast cancer. Please consult your doctor if you are pregnant, planning to conceive or a breastfeeding mother before starting Sizonorm Injection 1 ml. Avoid consuming alcohol during the treatment, as it might lead to increased dizziness and drowsiness. Avoid driving or operating machinery, as this medicine may decrease your mental alertness, making you feel dizzy or drowsy. Sizonorm Injection 1 ml is not recommended for children below 12 years of age as safety and effectiveness have not been established.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Sizonorm Injection 1 ml:
Taking ziprasidone with Sizonorm Injection 1 ml can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Ziprasidone with Sizonorm Injection 1 ml is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Sizonorm Injection 1 ml:
Coadministration of Sizonorm Injection 1 ml and Haloperidol can increase the risk of developing irregular heart rhythms.

How to manage the interaction:
Taking Sizonorm Injection 1 ml and Haloperidol together is generally avoided as it can lead to an interaction, but it can be taken when a doctor advises. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Sizonorm Injection 1 ml:
Taking Sizonorm Injection 1 ml with Pentazocine can increase the risk of serious side effects.

How to manage the interaction:
Although there is a possible interaction between Pentazocine and Sizonorm Injection 1 ml, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, drowsiness, difficulty concentrating, and impairment in judgment. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Sizonorm Injection 1 ml:
Taking Gatifloxacin and Sizonorm Injection 1 ml can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Gatifloxacin and Sizonorm Injection 1 ml together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Sizonorm Injection 1 ml:
Coadministration of Sizonorm Injection 1 ml with Propylthiouracil can increase the risk of developing infections.

How to manage the interaction:
Co-administration of Propylthiouracil with Sizonorm Injection 1 ml can possibly result in an interaction, but it can be taken if your doctor has advised it. However, contact a doctor if you experience any symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, or burning urination. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Sizonorm Injection 1 ml:
Using chloroquine together with Sizonorm Injection 1 ml can increase the risk of an irregular heart rhythm

How to manage the interaction:
Taking chloroquine and Sizonorm Injection 1 ml together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Sizonorm Injection 1 ml:
Taking amisulpride with Sizonorm Injection 1 ml increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Although taking amisulpride along with Sizonorm Injection 1 ml can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Sizonorm Injection 1 ml:
Combining Sizonorm Injection 1 ml with Escitalopram can increase the risk of adverse effects.

How to manage the interaction:
Taking Escitalopram with Sizonorm Injection 1 ml together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these symptoms - dizziness, feeling lightheaded or faint, heart palpitations, irregular heart rhythm, difficulty breathing, a heart condition, or severe and prolonged diarrhea or vomiting, contact your doctor right away. Do not stop using any medications without talking to your doctor.
How does the drug interact with Sizonorm Injection 1 ml:
Taking Morphine with Sizonorm Injection 1 ml may increase the risk of central nervous system depression, which can lead to breathing difficulty and unconsciousness.

How to manage the interaction:
Coadministration of Morphine and Sizonorm Injection 1 ml together can cause an interaction, it can be taken if a doctor has suggested it. However, if you notice any symptoms like dizziness, drowsiness, difficulty concentrating, impaired judgment, reaction speed, and motor coordination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Sizonorm Injection 1 ml:
Taking Sizonorm Injection 1 ml and Efavirenz can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Sizonorm Injection 1 ml and Efavirenz together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain proper weight by following a healthy diet.
  • Exercise regularly as it helps in less cognitive decline and brain volume loss.
  • Avoid smoking and alcohol consumption.
  • Try to avoid stress by practising meditation or yoga.
  • Include fruits and vegetables in your diet as they contain antioxidants.
  • Eat nutritious food as it helps in cognitive stimulation.
  • Limit foods with high cholesterol and saturated fats.
  • Cut down on sugar, salt and processed foods.
  • Drink plenty of water.
  • Follow a regular sleep pattern.

Habit Forming

No

Therapeutic Class

ANTIPSYCHOTICS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Sizonorm Injection 1 ml contains 'Fluphenazine,' an antipsychotic medication that affects the balance of neurotransmitters in the brain, thus improving mood, behaviour, and thoughts in schizophrenia.

Before using Sizonorm Injection 1 ml, let your doctor know if you have a medical history of liver or kidney diseases, heart problems (history of stroke), breathing problems (asthma, emphysema), pheochromocytoma (adrenal gland tumour), Parkinson's disease, fits, low white blood cells, glaucoma, blood problems (leukopenia, thrombocytopenia), low blood calcium levels, enlarged prostate, breast cancer, and Reye's syndrome (a rare, but serious condition that causes swelling in the brain and liver damage). Please let your doctor know if you have any other medical problems before starting Sizonorm Injection 1 ml.

Sizonorm Injection 1 ml is not recommended for older dementia patients since it can lead to serious side effects like heart failure, fast/irregular heartbeat, and pneumonia. However, please discuss with the doctor possibly safer treatments for dementia-related behaviour problems.

Sizonorm Injection 1 ml may cause dizziness. It is advised to avoid getting up too fast from a sitting or lying position that can make you feel dizzy.

Dry mouth could be a side-effect of Sizonorm Injection 1 ml. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help stimulate saliva and prevent drying of the mouth.

Drug-Drug Interactions Checker List

  • CLONIDINE
  • CODEINE
  • HYDROCODONE
  • ALPRAZOLAM
  • LORAZEPAM
  • CARISOPRODOL
  • CYCLOBENZAPRINE
  • CETIRIZINE
  • DIPHENHYDRAMINE
  • LITHIUM
  • QUINIDINE

Special Advise

This medicine may interfere with tests for pregnancy and phenylketonuria and some urine tests. Let your doctor or laboratory staff know you are taking Sizonorm Injection 1 ml if you undergo other medical examinations.

Disease/Condition Glossary

Schizophrenia: It is a condition in which the person may see, hear or feel things that are not there, believe things that are not true, or feel unusually suspicious or confused. Symptoms include hallucinations, delusions, thought disorders, movement disorders, disorganised thinking, loss of interest, lack of emotions, etc. Schizophrenia is triggered by physical, genetic, psychological, and environmental factors. Patients suffering from this disease may require lifelong treatment. Treatment involves a combination of medications, psychotherapy and care services.

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