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  3. Nexodec-D 40/30 Capsule 10's

Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS
Prescription drug
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Non returnable*
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Manufacturer/Marketer :

Gallberry Life Sciences Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Nexodec-D 40/30 Capsule 1

Nexodec-D 40/30 Capsule 1 belongs to a group of gastrointestinal agents used to treat gastroesophageal reflux disease (GERD), Zollinger-Ellison syndrome, and stomach ulcers. The stomach is usually protected from acid by a mucous layer. In some cases, due to excess acid production, the mucous layer gets eroded, which leads to complications like GERD, acidity, peptic ulcers and Zollinger-Ellison syndrome.

Nexodec-D 40/30 Capsule 1 is a combination of two drugs: Esomeprazole (proton pump inhibitor) and Domperidone (a dopamine antagonist). Esomeprazole works by blocking an enzyme called gastric proton pump, which is responsible for the production of acid Domperidone works by increasing the movements and contractions of stomach muscle. Together, Nexodec-D 40/30 Capsule 1 helps in treating acidity-related problems.

You are advised to take Nexodec-D 40/30 Capsule 1 for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as dry mouth, stomach pain, diarrhoea, headache, and flatulence. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Consult your doctor before taking Nexodec-D 40/30 Capsule 1 if you are pregnant or breastfeeding. Nexodec-D 40/30 Capsule 1 may cause dizziness, so drive only if you are alert. Nexodec-D 40/30 Capsule 1 should not be given to children as safety has not been established. Avoid consuming alcohol and Nexodec-D 40/30 Capsule 1 as it could lead to increased drowsiness and elevate stomach acid production. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Uses of Nexodec-D 40/30 Capsule 1

Gastroesophageal reflux disease (GERD), Zollinger-Ellison syndrome, Stomach ulcers

Directions for Use

Take Nexodec-D 40/30 Capsule 1 1 hour prior to food. Swallow Nexodec-D 40/30 Capsule 1 as a whole with a glass of water; do not chew or crush it.

Medicinal Benefits

Nexodec-D 40/30 Capsule 1 is a combination of two drugs: Esomeprazole and Domperidone. Nexodec-D 40/30 Capsule 1 is used to treat gastroesophageal reflux disease (GERD), Zollinger-Ellison syndrome, and stomach ulcers. It may also be indicated in the treatment of nausea, vomiting, fullness of the stomach, belching, heavy bloating, heartburn, acidity, gas, upper abdominal pain, erosive oesophagitis, and swallowing problems. Esomeprazole is a proton pump inhibitor that blocks an enzyme called gastric proton pump, responsible for acid production. Domperidone is a dopamine antagonist which works by increasing the movements and contractions of stomach muscles. Together, Nexodec-D 40/30 Capsule 1 helps in treating acidity-related problems.

Storage

Keep Nexodec-D 40/30 Capsule 1 out of reach and sight of children.
Side effects of Nexodec-D 40/30 Capsule 10's
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.

Drug Warnings

Do not take Nexodec-D 40/30 Capsule 1 if you are allergic to any of its contents or other proton pump inhibitors (such as pantoprazole, rabeprazole, lansoprazole or omeprazole); if you are taking nelfinavir (used to treat HIV); if you have prolactinoma (tumour of the pituitary gland), blockage in intestines, bleeding in stomach or intestine, moderate to severe liver disease, low level of potassium or magnesium or high levels of magnesium, or heart problems. Inform your doctor before taking Nexodec-D 40/30 Capsule 1 if you have severe kidney, heart or liver disease, or if you are due to have Chromogranin A blood test; if you have fungal infections, heart problems or HIV infection. Talk to your doctor if you experience weight loss, problems with swallowing, stomach pain, indigestion, vomit food or blood, or if you pass black stools while taking Nexodec-D 40/30 Capsule 1. On long-term treatment, Nexodec-D 40/30 Capsule 1 may cause low magnesium levels, vitamin B12 levels, and might increase the risk of bone fractures; the doctor may advise regular tests for monitoring your condition. Consult your doctor if you are pregnant or breastfeeding. Nexodec-D 40/30 Capsule 1 may cause dizziness, so drive only if you are alert. Nexodec-D 40/30 Capsule 1 should not be given to children as safety has not been established. Avoid consuming alcohol along with Nexodec-D 40/30 Capsule 1 as it could lead to increased drowsiness and can elevate the production of stomach acid. A prolonged intake of Nexodec-D 40/30 Capsule 1 is linked with a greater risk of Clostridium difficile-associated diarrhoea, so if you develop diarrhoea that does not improve, immediately consult a doctor. 

Drug-Drug Interactions

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EsomeprazoleRilpivirine
Critical

Drug-Drug Interactions

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EsomeprazoleRilpivirine
Critical
How does the drug interact with Nexodec-D 40/30 Capsule 10's :
Nexodec-D 40/30 Capsule 10's may reduce rilpivirine absorption and blood levels, making the medicine less effective against HIV.

How to manage the interaction:
Although taking Nexodec-D 40/30 Capsule 10's with Rilpivirine can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if your symptoms do not improve. Do not discontinue using any medications without consulting a doctor.
How does the drug interact with Nexodec-D 40/30 Capsule 10's :
Coadministration of Nexodec-D 40/30 Capsule 10's with Cisapride can increase the blood levels of Nexodec-D 40/30 Capsule 10's .

How to manage the interaction:
There may be a possibility of interaction between Nexodec-D 40/30 Capsule 10's and Cisapride, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.
DomperidoneToremifene
Severe
How does the drug interact with Nexodec-D 40/30 Capsule 10's :
Coadministration of Nexodec-D 40/30 Capsule 10's with Toremifene can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Nexodec-D 40/30 Capsule 10's and Toremifene together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Nexodec-D 40/30 Capsule 10's :
Combining Mizolastine with Nexodec-D 40/30 Capsule 10's can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Although taking Nexodec-D 40/30 Capsule 10's and Mizolastine together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
DomperidoneMethadone
Severe
How does the drug interact with Nexodec-D 40/30 Capsule 10's :
Coadministration of Nexodec-D 40/30 Capsule 10's with Methadone can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Nexodec-D 40/30 Capsule 10's and Methadone together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Nexodec-D 40/30 Capsule 10's :
Coadministration of Nexodec-D 40/30 Capsule 10's with Ketoconazole can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Nexodec-D 40/30 Capsule 10's and Ketoconazole together can cause an interaction, it can be taken if a doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Nexodec-D 40/30 Capsule 10's :
Coadministration of Nexodec-D 40/30 Capsule 10's with Ritonavir can increase the blood levels of Nexodec-D 40/30 Capsule 10's .

How to manage the interaction:
There may be a possibility of interaction between Nexodec-D 40/30 Capsule 10's and Ritonavir, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.
DomperidoneBepridil
Severe
How does the drug interact with Nexodec-D 40/30 Capsule 10's :
Co-administration of Domeperidone and Bepridil can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Nexodec-D 40/30 Capsule 10's and Bepridil together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Nexodec-D 40/30 Capsule 10's :
Coadministration of Nexodec-D 40/30 Capsule 10's with Clarithromycin can increase the risk of side effects.

How to manage the interaction:
There may be a possibility of interaction between Nexodec-D 40/30 Capsule 10's and Clarithromycin, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Nexodec-D 40/30 Capsule 10's :
Coadministration of Nexodec-D 40/30 Capsule 10's with Citalopram can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Nexodec-D 40/30 Capsule 10's and Citalopram together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat smaller meals more often.
  • Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.
  • Maintain a healthy weight by regular exercising.
  • Avoid lying down after eating as it causes acid reflux.
  • Avoid tight-fitting clothes as it might increase the pressure on the abdomen leading to acid reflux.
  • Practise relaxation techniques and avoid stress by doing yoga or meditation.
  • Avoid foods such as high-fat food, spicy food, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea and soda. 
  • Avoid sitting continuously as it may trigger acidity. Take a break of 5minutes every hour by doing brisk walking or stretching.

Side Effects of Nexodec-D 40/30 Capsule 1

  • Dry mouth
  • Stomach pain
  • Diarrhoea
  • Headache
  • Flatulence

Habit Forming

No

Therapeutic Class

GASTROINTESTINAL AGENTS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Nexodec-D 40/30 Capsule 1 contains Esomeprazole and Domperidone. Esomeprazole works by blocking the action of an enzyme called gastric proton pump, which is responsible for the production of acid. Domperidone works by increasing the movements and contractions of stomach muscles. Together, Nexodec-D 40/30 Capsule 1 helps in treating acidity.

Diarrhoea might be a side-effect of Nexodec-D 40/30 Capsule 1. Drink enough fluids and eat non-spicy food if you experience diarrhoea. Consult your doctor if you experience excessive diarrhoea or if you find blood in your stools.

Avoid lying down immediately after meals to prevent acid reflux. Raise the head of the bed 10-20cm by putting a pillow so that the head and chest are above the waist. This helps in preventing acid reflux.

Dry mouth could be a side-effect of Nexodec-D 40/30 Capsule 1. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help stimulate saliva and thereby prevent drying of the mouth.

Nexodec-D 40/30 Capsule 1 contains domperidone which helps in treating nausea and vomiting by increasing the movements and contractions of stomach muscles.

Do not take Nexodec-D 40/30 Capsule 1 for longer durations unless prescribed by the doctor. Consult your doctor if your condition does not improve even after taking Nexodec-D 40/30 Capsule 1 for 14days.

Nexodec-D 40/30 Capsule 1 should not be taken along with HIV medicines such as atazanavir, ritonavir, nelfinavir, and saquinavir as Nexodec-D 40/30 Capsule 1 might affect their absorption. Consult your doctor before taking Nexodec-D 40/30 Capsule 1 with other medicines to avoid unpleasant side-effects.

On long-term treatment, Nexodec-D 40/30 Capsule 1 might increase the risk of bone fracture in the spine, wrist or hip. Inform your doctor if you have osteoporosis or if you are taking corticosteroids, as they can increase the risk of bone fractures.

Drug-Drug Interactions Checker List

  • ATAZANAVIR
  • SAQUINAVIR
  • RITONAVIR
  • NELFINAVIR
  • WARFARIN
  • CLOPIDOGREL
  • KETOCONAZOLE
  • ITRACONAZOLE
  • VORICONAZOLE
  • FLUCONAZOLE
  • ERLOTINIB
  • TOREMIFENE
  • VANDETANIB
  • VINCAMINE
  • DIAZEPAM
  • PHENYTOIN
  • CILOSTAZOL
  • CISAPRIDE
  • DOLASETRON
  • TACROLIMUS
  • RIFAMPICIN
  • ERYTHROMYCIN
  • CLARITHROMYCIN
  • MOXIFLOXACIN
  • PENTAMIDINE
  • TELITHROMYCIN
  • LEVOTHYROXINE
  • METHOTREXATE
  • CITALOPRAM
  • ESCITALOPRAM
  • DIGOXIN
  • HALOFANTRINE
  • HALOPERIDOL
  • PIMOZIDE
  • SERTINDOLE
  • MEQUITAZINE
  • MIZOLASTINE
  • AMIODARONE
  • DRONEDARONE
  • QUINIDINE
  • DISOPYRAMIDE
  • DOFETILIDE
  • SOTALOL
  • DILTIAZEM
  • VERAMAPIL

Special Advise

  • Inform your doctor before taking Nexodec-D 40/30 Capsule 1 if you are due to have Chromogranin A blood test.
  • Nexodec-D 40/30 Capsule 1 may cause changes in blood tests. Inform the person doing the tests that you are taking Nexodec-D 40/30 Capsule 1.

Disease/Condition Glossary

Gastroesophageal reflux disease (GERD): It occurs when stomach acid frequently flows back into the food pipe (oesophagus). This backflow (acid reflux) irritates the food pipe and causes heartburn. Symptoms include heartburn, sour or bitter taste in the mouth, and difficulty swallowing.

Stomach/Peptic ulcers: They are sores that develop on the stomach and intestine lining due to erosion of the stomach's protective lining. Symptoms include nausea, appetite changes, bloody or dark stools, unexplained weight loss, vomiting, and indigestion.

Zollinger-Ellison syndrome: It is characterised by the formation of tumours in the upper part of the small intestine, which leads to excess acid production. Symptoms include bloating, burping, weight loss, loss of appetite, nausea, and vomiting. 

Have a query?

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Nexodec-D 40/30 Capsule 1. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.

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Pregnancy

Caution

Consult your doctor before taking Nexodec-D 40/30 Capsule 1 if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking Nexodec-D 40/30 Capsule 1; your doctor will decide whether Nexodec-D 40/30 Capsule 1 can be taken by breastfeeding mothers or not.

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Driving

Caution

Nexodec-D 40/30 Capsule 1 may cause dizziness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed. Consult your doctor before taking Nexodec-D 40/30 Capsule 1 if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Consult your doctor before taking Nexodec-D 40/30 Capsule 1 if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Nexodec-D 40/30 Capsule 1 should not be given to children as safety and effectiveness were not established.

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