Acebrophylline+cetirizine+montelukast
About
Acebrophylline+cetirizine+montelukast belongs to a class of medicines known as respiratory stimulants, primarily used to treat and prevent respiratory disorders like asthma attacks, chronic obstructive pulmonary diseases (COPD), and allergic rhinitis (hay fever). Asthma is a breathing problem in which airways narrow, swell and produce extra mucus, leading to difficulty breathing. COPD is a group of lung diseases that mainly include emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of your bronchial tubes). Allergic rhinitis is an inflammation of the nose caused by an allergen, such as pollen, dust, mould, or flakes of skin from certain animals.
Acebrophylline+cetirizine+montelukast is a combination of three medicines: Acebrophylline (bronchodilator), cetirizine (antiallergic), and montelukast (leukotriene receptor antagonist). Acebrophylline has mucoregulating/mucolytic (dissolves thick mucus and helps relieve breathing difficulties) and anti-inflammatory properties. Acebrophylline+cetirizine+montelukast contains cetirizine (anti-allergic), which is used to treat allergies as it blocks the effects of a chemical messenger known as ‘histamine,’ which is naturally involved in allergic reactions. Montelukast belongs to the class of leukotriene receptor antagonists. Leukotrienes are inflammatory chemicals that are released by the body when an allergen comes into contact. These chemicals cause swelling in the lungs and tightening of the airway muscles, which are the primary causes of asthma attacks. Montelukast blocks these leukotrienes, thereby reducing inflammation and swelling in the nose. It also inhibits bronchoconstriction (narrowing of airways in the lungs that lead to breathing difficulties) and is used in treating asthma and allergic rhinitis.
Take Acebrophylline+cetirizine+montelukast as prescribed by your doctor. You are advised to take Acebrophylline+cetirizine+montelukast for as long as your doctor has prescribed it for you depending on your medical conditions. You may experience nausea, vomiting, upset stomach, diarrhoea, flu-like symptoms, skin rash, dryness in the mouth, headache, sleepiness, fatigue, rash, itching, hives, breathing problems, and increased white blood cell count. Most of these side effects of Acebrophylline+cetirizine+montelukast do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Therapy with leukotriene receptor antagonists like Montelukast should be cautiously administered in patients with neuropsychiatric disorders. There are chances of developing psychiatric-type effects, including agitation, aggressive behaviour, anxiety, depression, abnormal dreams, and hallucinations. Acebrophylline+cetirizine+montelukast may not be used during pregnancy since it may affect the unborn baby. Also, there are chances of Montelukast excreting into breast milk during breastfeeding. It is advisable to check with your doctor if you are pregnant, currently breastfeeding, or taking any other prescribed or non-prescribed medicines before starting Acebrophylline+cetirizine+montelukast.a
Uses of Acebrophylline+cetirizine+montelukast
Medicinal Benefits
Acebrophylline+cetirizine+montelukast belongs to a class of medicines known as respiratory stimulants, primarily used to treat and prevent respiratory disorders like asthma attacks, chronic obstructive pulmonary diseases (COPD), and allergic rhinitis (hay fever). Acebrophylline+cetirizine+montelukast is a combination of three medicines: Acebrophylline (bronchodilator), cetirizine (antiallergic), and montelukast (leukotriene receptor antagonist). Acebrophylline has mucoregulating/mucolytic (dissolves thick mucus and helps relieve breathing difficulties) and anti-inflammatory properties. Acebrophylline+cetirizine+montelukast contains cetirizine (anti-allergic), which is used to treat allergies as it blocks the effects of a chemical messenger known as ‘histamine,’ which is naturally involved in allergic reactions. Montelukast belongs to the class of leukotriene receptor antagonists. Leukotrienes are inflammatory chemicals that are released by the body when an allergen comes into contact. These chemicals cause swelling in the lungs and tightening of the airway muscles, which are the primary causes of asthma attacks. Montelukast blocks these leukotrienes, thereby reducing inflammation and swelling in the nose. It also inhibits bronchoconstriction (narrowing of airways in the lungs that lead to breathing difficulties) and is used in treating asthma and allergic rhinitis.
Directions for Use
Storage
Side Effects of Acebrophylline+cetirizine+montelukast
- Nausea
- Vomiting
- Upset stomach
- Diarrhoea
- Flu-like symptoms
- Skin rash
- Dryness in mouth
- Headache
- Sleepiness
- Fatigue
- Rash
- Itching
- Breathing problems
- Increased white blood cell count.
In-Depth Precautions and Warning
Drug Warnings
Do not stop taking this medicine of your own unless advised by your doctor. Before taking Acebrophylline+cetirizine+montelukast, let your doctor know if have heart, liver, kidney, and lung diseases, neuropsychiatric disorders like seizures (fits) and depression, phenylketonuria (birth defect caused by the build-up of an amino acid called phenylalanine in the body), hyperthyroidism (overactive thyroid), high blood pressure, stomach ulcers, and viral infections. Acebrophylline+cetirizine+montelukast is not intended for use during an acute asthma attack. Patients should avoid taking overdosage of Acebrophylline+cetirizine+montelukast because Acebrophylline+cetirizine+montelukast contains cetirizine which may cause an increased risk of sleepiness and drowsiness at higher doses. Therapy with leukotriene receptor antagonists like Montelukast should be cautiously administered in patients with neuropsychiatric disorders. There are chances of developing psychiatric-type effects, including agitation, aggressive behaviour, anxiety, depression, abnormal dreams, and hallucinations. Acebrophylline is Acebrophylline+cetirizine+montelukast that may not be used during pregnancy since it may affect the unborn baby. Montelukast may excrete into the breast milk during breastfeeding and affect the newborn. Please seek medical advice if you are pregnant, currently breastfeeding, or taking any other prescribed or non-prescribed medicines before starting Acebrophylline+cetirizine+montelukast.
Drug Interactions
Drug-Drug Interactions: Acebrophylline+cetirizine+montelukast may interact with medicines used for nausea and vomiting caused by cancer (aprepitant, fosaprepitant), antacid (cimetidine), antibiotics (ciprofloxacin, erythromycin, amoxicillin, doxycycline, rifampicin), blood thinner (warfarin), medicines for fits disorder (phenytoin), water pills (furosemide).
Drug-Food Interactions: Limit alcohol intake since it may increase the occurrence of side effects like drowsiness.
Drug-Disease Interactions: Acebrophylline+cetirizine+montelukast is contraindicated in heart, liver, kidney, and lung diseases, neuropsychiatric disorders like seizures (fits) and depression, phenylketonuria (birth defect caused by the build-up of an amino acid called phenylalanine in the body), hyperthyroidism (overactive thyroid), high blood pressure, stomach ulcers, and viral infections.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionAvoid drinking alcohol while taking Acebrophylline+cetirizine+montelukast as it can worsen your side effects like drowsiness.
Pregnancy
cautionAcebrophylline+cetirizine+montelukast is recommended to use with caution and under doctor's supervision during pregnancy since Acebrophylline in Acebrophylline+cetirizine+montelukast may affect the unborn baby. Acebrophylline is not recommended during parturition (childbirth). Please consult your doctor if you are planning to conceive or already pregnant before starting Acebrophylline+cetirizine+montelukast.
Breast Feeding
cautionThere is limited data on how Acebrophylline+cetirizine+montelukast affects breastfeeding. Please consult your doctor before starting Acebrophylline+cetirizine+montelukast.
Driving
cautionDo not drive or operate machinery if you experience drowsiness or difficulty in concentrating while using Acebrophylline+cetirizine+montelukast. Acebrophylline+cetirizine+montelukast may affect your ability to drive. Seek medical attention if the symptoms persist longer.
Liver
cautionAcebrophylline+cetirizine+montelukast should be used with caution in patients with liver diseases. Let your doctor know if you have any history of hepatic impairment caused by alcohol use or cirrhosis or any other form of liver disease, since it may cause decreased metabolism of Montelukast. Acebrophylline+cetirizine+montelukast may also cause liver enzyme changes. Your doctor will weigh the benefits and potential risks before prescribing Acebrophylline+cetirizine+montelukast.
Kidney
cautionAcebrophylline+cetirizine+montelukast should be used with caution in patients with kidney diseases. Let your doctor know if you have any history of kidney diseases. Your doctor will weigh the benefits and potential risks before prescribing Acebrophylline+cetirizine+montelukast.
Children
cautionAcebrophylline+cetirizine+montelukast is not recommended for use for children less than two years of age. The dose may have to be adjusted by your doctor depending upon the condition of the child's disease and age.
Habit Forming
Diet & Lifestyle Advise
- Take the medication as directed by the doctor and at regular intervals. Do not use other over-the-counter medications, herbal or vitamin supplements without informing your pharmacist or doctor when you take Acebrophylline+cetirizine+montelukast.
- Know your triggers like allergens, such as pollen, dust, and food items that make your asthma severe.
- Quit smoking and avoid passive smoking. Smoking also reduces the effectiveness of the medicine.
- Eat a healthy diet and exercise regularly to strengthen your breathing muscles and boost your immune system.
- Learning breathing exercises will help you move more air in and out of your lungs.
Special Advise
- Montelukast in Acebrophylline+cetirizine+montelukast may sometimes cause liver enzyme changes. It is advised to inform your doctor if you are undergoing any Liver Function Tests.
Patients Concern
Disease/Condition Glossary
Asthma: It is a breathing problem in which airways narrow, swell and produce extra mucus, leading to difficulty breathing. Symptoms of asthma include coughing, wheezing, and chest tightness.
Chronic obstructive pulmonary disease (COPD): It is a group of lung diseases that block airflow and make it difficult to breathe. The most common COPD is emphysema and chronic bronchitis.
Allergic rhinitis: An inflammation of the nose caused by an allergen, such as pollen, dust, mould, or flakes of skin from certain animals. Its symptoms include itchy, watery eyes, an itchy nose, sneezing, and a runny nose.
FAQs
Acebrophylline+cetirizine+montelukast treats and prevents respiratory disorders like asthma attacks, chronic obstructive pulmonary diseases (COPD), and allergic rhinitis. It consists of Acebrophylline and Montelukast. Acebrophylline is a bronchodilator that works by relaxing muscles and widening the airways of the lungs. Cetirizine (anti-allergic), which is used to treat allergies as it blocks the effects of a chemical messenger known as ‘histamine,’ which is naturally involved in allergic reactions. Montelukast is a leukotriene receptor antagonist that blocks leukotrienes (chemicals released in response when a body comes in contact with an allergen) and reduces inflammation and swelling in the nose.
Take Acebrophylline+cetirizine+montelukast in the dose and duration prescribed by your doctor. Acebrophylline+cetirizine+montelukast should preferably be taken after food to avoid any stomach discomfort or upset stomach.
Acebrophylline+cetirizine+montelukast is not recommended for use during a sudden asthma attack since it does not act right away. It is advised to please consult your doctor to prescribe a fast-acting inhaler for rescuing your sudden breathing problems.
Therapy with leukotriene receptor antagonists like Montelukast may worsen the symptoms of psychotic events in patients with a history of mental illness. Careful administration and monitoring are essential before taking Acebrophylline+cetirizine+montelukast in patients with neuropsychiatric disorders. Please consult your doctor before taking Acebrophylline+cetirizine+montelukast if you have been diagnosed or have a history of mental illness like depression, seizures (fits), etc.
It is essential to let your doctor know if you have any history of heart, liver, kidney, and lung diseases, neuropsychiatric disorders like seizures (fits) and depression, phenylketonuria (birth defect caused by the build-up of an amino acid called phenylalanine in the body), hyperthyroidism (overactive thyroid), high blood pressure, stomach ulcers, and viral infections before taking Acebrophylline+cetirizine+montelukast.