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Acebrophylline+desloratadine+montelukast

About Acebrophylline+desloratadine+montelukast

Acebrophylline+desloratadine+montelukast belongs to the class of drugs called respiratory stimulants primarily used to prevent and treat symptoms of asthma and chronic obstructive pulmonary disease (COPD). Asthma is a chronic (long-term) respiratory condition in which airways narrow, swell, and produce extra mucus, leading to difficulty breathing. COPD is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of bronchial tubes).

Acebrophylline+desloratadine+montelukast is a combination of three drugs, namely: Acebrophylline (bronchodilator), Desloratadine (antihistamine), and Montelukast (leukotriene receptor antagonist). Acebrophylline works by relaxing muscles and widening the airways of the lungs. Additionally, it also acts as a mucolytic (cough/sputum thinner) agent and helps in thinning and loosening phlegm (mucus) in the lungs, windpipe, and nose. Thereby helps to cough out easily and makes breathing easier by opening airways. Desloratadine works by blocking the action of histamine, a substance responsible for causing allergic reactions. Montelukast works by blocking the action of chemicals called leukotrienes that cause inflammation (swelling) and increased mucus production in the airways. Thereby reducing inflammation, mucus production, and narrowing in the airways.   

Take Acebrophylline+desloratadine+montelukast as prescribed. You are advised to take Acebrophylline+desloratadine+montelukast for as long as your doctor has recommended it based on your medical condition. Some people may experience nausea, vomiting, stomach upset, headache, and restlessness. Most of these side effects of Acebrophylline+desloratadine+montelukast do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. 

If you are allergic to Acebrophylline+desloratadine+montelukast or any other medicines, please tell your doctor. If your breathing worsens or you often wake up at night with asthma or experience chest tightness in the morning, please consult a doctor immediately, as these might be signs indicating that your asthma is not controlled properly and requires an alternate or additional treatment. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Acebrophylline+desloratadine+montelukast. Do not take Acebrophylline+desloratadine+montelukast if you have a heart rhythm disorder that causes fast heartbeats. Avoid taking Acebrophylline+desloratadine+montelukast if you have low blood pressure, irregular heartbeats, hemodynamic instability (unstable blood pressure), had a heart attack, kidney or liver diseases. 

Uses of Acebrophylline+desloratadine+montelukast

Asthma, Chronic obstructive pulmonary disease (COPD)

Medicinal Benefits

Acebrophylline+desloratadine+montelukast contains Acebrophylline (bronchodilator), Desloratadine (antihistamine), and Montelukast (leukotriene receptor antagonist) used to prevent and treat symptoms of asthma and chronic obstructive pulmonary disease (COPD). Acebrophylline relaxes muscles and widens the airways of the lungs. Additionally, it also acts as a mucolytic (cough/sputum thinner) agent and helps in thinning and loosening phlegm (mucus) in the lungs, windpipe and nose. Thereby, helps to cough out easily and makes breathing easier by opening airways. Desloratadine is an anti-allergic drug that helps to provide relief from allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, and congestion or stiffness. Montelukast reduces inflammation, mucus production and narrowing in the airways. Acebrophylline+desloratadine+montelukast helps to prevent an asthma attack.

Directions for Use

Take Acebrophylline+desloratadine+montelukast with food to avoid stomach upset or take it as advised by the doctor. Swallow it as a whole with a glass of water. Do not break, crush or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Acebrophylline+desloratadine+montelukast

  • Nausea
  • Vomiting
  • Stomach upset
  • Headache 
  • Restlessness

Drug Warnings

If you are allergic to Acebrophylline+desloratadine+montelukast or any other medicines, please tell your doctor. If your breathing worsens or you often wake up at night with asthma, experience chest tightness in the morning, please consult a doctor immediately as these might be signs indicating that your asthma is not controlled properly and requires an alternate or additional treatment. Regular monitoring of potassium levels is recommended while taking Acebrophylline+desloratadine+montelukast as it may cause low potassium levels in the blood. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Acebrophylline+desloratadine+montelukast. Do not take Acebrophylline+desloratadine+montelukast if you have a heart rhythm disorder that causes fast heartbeats. Avoid taking Acebrophylline+desloratadine+montelukast if you have low blood pressure, irregular heartbeats, hemodynamic instability (unstable blood pressure), had a heart attack, kidney or liver diseases. 

Drug Interactions

Drug-Drug Interaction: Acebrophylline+desloratadine+montelukast may interact with water pills (furosemide), medicines used to treat gout (allopurinol), antacid (cimetidine), antibiotics (ciprofloxacin, erythromycin, azithromycin, amoxicillin, doxycycline), drugs used to lower high blood pressure (diltiazem, verapamil), heart-related medicines (isoprenaline), anthelmintic (thiabendazole), antifungal (ketoconazole), antidepressant (fluoxetine), corticosteroids (prednisone) and oral contraceptives (ethinylestradiol). 

Drug-Food Interaction: Acebrophylline+desloratadine+montelukast may interact with alcohol. Therefore, avoid intake of alcohol with Acebrophylline+desloratadine+montelukast as it may increase drowsiness. Also, avoid or limit the intake of caffeine with Acebrophylline+desloratadine+montelukast as it may cause side effects.

Drug-Disease Interaction: Avoid taking Acebrophylline+desloratadine+montelukast if you have low blood pressure, irregular heartbeats, hemodynamic instability (unstable blood pressure), had a heart attack. If you have hyperthyroidism (overactive thyroid), irregular heartbeats, viral infections, heart failure, high blood pressure, fits, gastric or duodenal ulcers, heart diseases, kidney or liver insufficiency, inform your doctor before taking Acebrophylline+desloratadine+montelukast. 

Drug-Drug Interactions Checker List:

  • FUROSEMIDE
  • ALLOPURINOL
  • CIMETIDINE
  • CIPROFLOXACIN
  • ERYTHROMYCIN
  • AZITHROMYCIN
  • AMOXICILLIN
  • DOXYCYCLINE
  • DILTIAZEM
  • VERAPAMIL
  • ISOPRENALINE
  • THIABENDAZOLE
  • KETOCONAZOLE
  • FLUOXETINE
  • PREDNISONE
  • ETHINYLESTRADIOL
  • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      Avoid consumption of alcohol with Acebrophylline+desloratadine+montelukast as it may increase drowsiness. Please consult a doctor before consuming alcohol with Acebrophylline+desloratadine+montelukast.

    • Safety Warning

      Pregnancy

      caution

      Acebrophylline+desloratadine+montelukast is given to pregnant women only if the doctor thinks the benefits are greater than the risks. Therefore, please inform your doctor if you are pregnant before using Acebrophylline+desloratadine+montelukast.

    • Safety Warning

      Breast Feeding

      caution

      It is unknown whether Acebrophylline+desloratadine+montelukast is excreted in human milk. Please consult a doctor before taking Acebrophylline+desloratadine+montelukast if you are breastfeeding.

    • Safety Warning

      Driving

      caution

      Drive only if you are alert after taking Acebrophylline+desloratadine+montelukast as it may cause drowsiness or dizziness in some people.

    • Safety Warning

      Liver

      caution

      Take Acebrophylline+desloratadine+montelukast with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

    • Safety Warning

      Kidney

      caution

      Take Acebrophylline+desloratadine+montelukast with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

    • Safety Warning

      Children

      caution

      Acebrophylline+desloratadine+montelukast should be used with caution in children in doses as prescribed by a doctor.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Eat foods rich in potassium such as tomatoes, bananas, asparagus, oranges, potatoes, avocados, dark leafy greens, and beetroots as potassium is important for lung function and a deficiency in potassium may cause breathing problems.
    • Drink plenty of fluids every day to thin mucus which makes it easier to cough out. 
    • Avoid foods such as cabbage, beans, garlic, onions, shrimp, pickled food, dried fruits, fried foods, carbonated drinks, wine, bottled lemon, and lime juice as it may worsen asthma symptoms.
    • Exercise regularly to strengthen your breathing muscles and boost your immune system. Learning breathing exercises will help you move more air in and out of your lungs.
    • Do meditation, deep breathing, regular exercise, and try progressive muscle relaxation techniques to get relief from stress and reduce the risk of an asthma attack.
    • Quit smoking as it may reduce the effectiveness of the Acebrophylline+desloratadine+montelukast and irritate the lungs and worsen breathing problems.

    Patients Concern

    Disease/Condition Glossary

    Asthma: It is a chronic (long-term) respiratory condition in which airways narrow, swell, and produce extra mucus, leading to difficulty in breathing. The symptoms of asthma include wheezing (whistling sound while breathing), shortness of breath, chest tightness, and cough, especially at night. The symptoms of mild persistent asthma may occur more than 2 times a week and up to 4 nights in a month, whereas, in the case of severe persistent asthma, the symptoms occur several times every day and most nights. The asthma treatment includes medication, breathing exercises, and self-care. 

    Chronic obstructive pulmonary disease (COPD): It is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of bronchial tubes). The major cause of COPD is smoking tobacco. Also, long-term exposure to fumes and chemicals may lead to COPD. The symptoms include chronic cough, shortness of breath, or wheezing (whistle sound while breathing).

    FAQs

    Acebrophylline+desloratadine+montelukast contains Acebrophylline, Desloratadine and Montelukast. Acebrophylline relaxes muscles and widens the airways of the lungs. Additionally, it also acts as a mucolytic (cough/sputum thinner) agent and helps in thinning and loosening phlegm (mucus) in the lungs, windpipe and nose. Thereby, helps to cough out easily and makes breathing easier by opening airways. Desloratadine is an anti-allergic drug that helps to provide relief from allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, and congestion or stiffness. Montelukast reduces inflammation, mucus production and narrowing in the airways.

    Acebrophylline+desloratadine+montelukast should be used with caution in patients suffering from fits as it may worsen the condition. Therefore, inform your doctor if you have a history of fits before taking Acebrophylline+desloratadine+montelukast so that the dose may be adjusted or an alternate medicine may be prescribed.

    You are not recommended to take erythromycin with Acebrophylline+desloratadine+montelukast as co-administration of these medicines may increase the risk of adverse effects of Acebrophylline+desloratadine+montelukast. However, please consult a doctor before using other medicines with Acebrophylline+desloratadine+montelukast.

    You are recommended to avoid taking Acebrophylline+desloratadine+montelukast if you are allergic to acebrophylline, ambroxol, theophylline or suffering from irregular heartbeats, hemodynamic instability (unstable blood pressure), low blood pressure, liver or kidney disorders or had a heart attack. However, inform your doctor if you have any of these conditions before taking Acebrophylline+desloratadine+montelukast.

    You are not recommended to smoke while taking Acebrophylline+desloratadine+montelukast as it may reduce the effectiveness of Acebrophylline+desloratadine+montelukast.

    No, you are not recommended to stop taking Acebrophylline+desloratadine+montelukast without consulting your doctor as it may worsen the condition or cause recurring symptoms. Therefore, take Acebrophylline+desloratadine+montelukast for as long as your doctor has prescribed it and if you experience any difficulty while taking Acebrophylline+desloratadine+montelukast, please consult your doctor.

    No, Acebrophylline+desloratadine+montelukast does not relieve sudden asthma symptoms. Therefore, it is advised to carry a rescue inhaler always to treat sudden asthma symptoms.

    Available Medicines for

    Acebrophylline+desloratadine+montelukast

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