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Acebrophylline+doxofylline

About Acebrophylline+doxofylline

Acebrophylline+doxofylline belongs to the class of drugs called bronchodilators primarily used to prevent and treat symptoms of asthma and chronic obstructive pulmonary disease (COPD). Asthma is a chronic (long-term) respiratory condition in which airways narrow, swell, and produce extra mucus, leading to difficulty in breathing. COPD is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of bronchial tubes).

Acebrophylline+doxofylline is a combination of two bronchodilator drugs, namely: Acebrophylline and Doxofylline. Acebrophylline+doxofylline works by relaxing muscles and widening the airways of the lungs. Thereby, it makes breathing easier by opening the airways. Additionally, Acebrophylline also acts as a mucolytic (cough/sputum thinner) agent and helps in thinning and loosening phlegm (mucus) in the lungs, windpipe, and nose. Thereby, it helps to cough out easily and makes breathing easier by opening airways.

Take Acebrophylline+doxofylline as prescribed by your doctor. You are advised to take Acebrophylline+doxofylline for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience diarrhea, nausea, vomiting, dizziness, headache, irritability, insomnia (difficulty in falling or staying asleep), fast heart rate, stomach discomfort, or drowsiness. Most of these side effects of Acebrophylline+doxofylline do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Acebrophylline+doxofylline or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, please consult a doctor before using Acebrophylline+doxofylline. Acebrophylline+doxofylline is not recommended for children below 6 years of age. Avoid alcohol consumption with Acebrophylline+doxofylline as it may reduce the effectiveness of Acebrophylline+doxofylline and increase drowsiness. If your breathing worsens or you often wake up at night with asthma, experience chest tightness in the morning, or last longer than usual, please consult a doctor immediately as these might be signs indicating that your asthma is not controlled properly and requires an alternate or additional treatment.

Uses of Acebrophylline+doxofylline

Asthma, Chronic obstructive pulmonary disease (COPD)

Medicinal Benefits

Acebrophylline+doxofylline is a combination of two bronchodilator drugs, namely: Acebrophylline and Doxofylline. Acebrophylline+doxofylline relaxes muscles and widens the airways of the lungs. Thereby, it makes breathing easier by opening the airways. Additionally, Acebrophylline also acts as a mucolytic (cough/sputum thinner) agent and helps in thinning and loosening phlegm (mucus) in the lungs, windpipe, and nose. Thereby, it helps to cough out easily and makes breathing easier by opening airways.

Directions for Use

Take Acebrophylline+doxofylline with food to avoid stomach upset or take it as advised by your doctor. Swallow it as a whole with a glass of water. Do not break, crush or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Acebrophylline+doxofylline

  • Diarrhoea
  • Nausea
  • Vomiting
  • Dizziness
  • Headache
  • Irritability
  • Insomnia (difficulty in falling or staying asleep)
  • Fast heart rate
  • Stomach discomfort
  • Drowsiness

Drug Warnings

If you are allergic to Acebrophylline+doxofylline or any other medicines, please tell your doctor. You are recommended to avoid taking Acebrophylline+doxofylline with chocolate and caffeinated foods such as cocoa beans or tea leaves as they may increase the risk of severity of side effects. If you are pregnant or breastfeeding, please consult a doctor before using Acebrophylline+doxofylline. Do not take Acebrophylline+doxofylline if you have low blood pressure, irregular heartbeats, hemodynamic instability (unstable blood pressure), or had a heart attack. Acebrophylline+doxofylline should be used with caution in congestive heart failure patients as these patients have slow drug clearance even after stopping treatment with Acebrophylline+doxofylline leading to high blood levels. If your breathing worsens or you often wake up at night with asthma, experience chest tightness in the morning, or lasts longer than usual, please consult a doctor immediately as these might be signs indicating that your asthma is not controlled properly and requires an alternate or additional treatment.

Drug Interactions

Drug-Drug Interaction: Acebrophylline+doxofylline may interact with water pills (furosemide), medicines used to treat gout (allopurinol), antacid (cimetidine), antibiotics (ciprofloxacin, erythromycin, amoxicillin, doxycycline, clindamycin, lincomycin), drugs used to lower high blood pressure (diltiazem, verapamil, propranolol), heart-related medicines (isoprenaline), anthelmintic (thiabendazole),  corticosteroids (prednisone), oral contraceptives (ethinylestradiol), central nervous system stimulant (ephedrine), flu vaccine (influenza vaccine) and anticonvulsants (phenytoin).

Drug-Food Interaction: Acebrophylline+doxofylline may interact with caffeine. Therefore, avoid intake of Acebrophylline+doxofylline with chocolate and caffeine-containing foods such as cocoa beans and tea leaves as they may increase the risk of severity of side effects. Also, avoid intake of alcohol with Acebrophylline+doxofylline as it may increase drowsiness.

Drug-Disease Interaction: Avoid taking Acebrophylline+doxofylline if you have low blood pressure, irregular heartbeats, hemodynamic instability (unstable blood pressure) or had a heart attack. If you have hyperthyroidism (overactive thyroid), irregular heartbeats, viral infections, congestive heart failure, hypoxemia (low oxygen levels in the blood), pulmonary heart diseases, heart failure, high blood pressure, fits, gastric or duodenal ulcers, heart diseases, kidney or liver insufficiency, inform your doctor before taking Acebrophylline+doxofylline.

Drug-Drug Interactions Checker List:

  • FUROSEMIDE
  • ALLOPURINOL
  • CIMETIDINE
  • CIPROFLOXACIN
  • ERYTHROMYCIN
  • AMOXICILLIN
  • DOXYCYCLINE
  • CLINDAMYCIN
  • LINCOMYCIN
  • DILTIAZEM
  • VERAPAMIL
  • PROPRANOLOL
  • ISOPRENALINE
  • THIABENDAZOLE
  • PREDNISONE
  • ETHINYLESTRADIOL
  • EPHEDRINE
  • INFLUENZA (LIVE ATTENUATED)
  • PHENYTOIN
  • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      Avoid consumption of alcohol with Acebrophylline+doxofylline as it may reduce the effectiveness of Acebrophylline+doxofylline and increase drowsiness. Please consult a doctor before consuming alcohol with Acebrophylline+doxofylline.

    • Safety Warning

      Pregnancy

      caution

      Please consult a doctor if you are pregnant. It is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

    • Safety Warning

      Breast Feeding

      caution

      It is unknown whether Acebrophylline+doxofylline is excreted in human milk. Please consult a doctor before taking Acebrophylline+doxofylline if you are breastfeeding.

    • Safety Warning

      Driving

      safe if prescribed

      Acebrophylline+doxofylline usually does not affect your ability to drive or operate machinery.

    • Safety Warning

      Liver

      caution

      Take Acebrophylline+doxofylline with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

    • Safety Warning

      Kidney

      caution

      Take Acebrophylline+doxofylline with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

    • Safety Warning

      Children

      caution

      Acebrophylline+doxofylline is not recommended for children below 6 years of age as the safety and effectiveness were not established. However, please consult a doctor before giving Acebrophylline+doxofylline for children.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Eat foods rich in potassium such as tomatoes, bananas, asparagus, oranges, potatoes, avocados, dark leafy greens, and beetroots as potassium is important for lung function and a potassium deficiency may cause breathing problems.
    • Drink plenty of fluids every day to thin mucus which makes it easier to cough out.
    • Maintain a diet that includes complex carbohydrates such as lentils, beans, barley, oats, quinoa, bran, peas, and potatoes with skin.
    • Limit or avoid the intake of caffeinated drinks such as tea, coffee, soda, and energy drinks like red bull.
    • Eat protein-rich foods such as meat, fish (particularly salmon, sardines, and mackerel), eggs, and poultry.
    • Exercise regularly to strengthen your breathing muscles and boost your immune system. Learning breathing exercises will help you move more air in and out of your lungs.
    • Quit smoking as it may reduce the effectiveness of the Acebrophylline+doxofylline and irritate the lungs worsening breathing problems.

    Special Advise

    Regular blood tests are recommended while taking Acebrophylline+doxofylline to monitor potassium levels and levels of Acebrophylline+doxofylline in the blood.

    Patients Concern

    Disease/Condition Glossary

    Asthma: It is a chronic (long-term) respiratory condition in which airways narrow, swell, and produce extra mucus, leading to difficulty in breathing. The symptoms of asthma include wheezing (whistling sound while breathing), shortness of breath, chest tightness, and cough, especially at night. The symptoms of mild persistent asthma may occur more than 2 times a week and up to 4 nights in a month, whereas, in the case of severe persistent asthma, the symptoms occur several times every day and most nights. The treatment for asthma includes medication, breathing exercises, and self-care.

    Chronic obstructive pulmonary disease (COPD): It is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of bronchial tubes). The major cause of COPD is smoking tobacco. Also, long-term exposure to fumes and chemicals may lead to COPD. The symptoms include chronic cough, shortness of breath, or wheezing (whistle sound while breathing).

    FAQs

    Acebrophylline+doxofylline is a combination of two drugs, namely: Acebrophylline and Doxofylline. Acebrophylline+doxofylline works by relaxing muscles and widening the airways of the lungs. Thereby, it makes breathing easier by opening airways.

    You are not recommended to take erythromycin with Acebrophylline+doxofylline as co-administration of these medicines may increase the risk of adverse effects of Acebrophylline+doxofylline. However, please consult a doctor before using other medicines with Acebrophylline+doxofylline.

    You are not recommended to smoke while taking Acebrophylline+doxofylline as it may reduce the effectiveness of Acebrophylline+doxofylline.

    You are recommended to avoid intake chocolate and caffeine-containing foods such as cocoa beans and tea leaves with Acebrophylline+doxofylline as they may increase the risk of severity of side effects.

    You are not recommended to stop taking Acebrophylline+doxofylline without consulting your doctor as it may worsen the condition or cause recurring symptoms. Therefore, take Acebrophylline+doxofylline for as long as your doctor has prescribed it and if you experience any difficulty while taking Acebrophylline+doxofylline, please consult your doctor.

    Acebrophylline+doxofylline does not relieve sudden asthma symptoms. Therefore, it is advised to carry a rescue inhaler always to treat sudden asthma symptoms.

    Available Medicines for

    Acebrophylline+doxofylline

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