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Acebrophylline+montelukast

About

Acebrophylline+montelukast is a respiratory medication, primarily used to treat and prevent respiratory disorders like asthma attacks, chronic obstructive pulmonary diseases (COPD) and allergic rhinitis (hay fever). Asthma is a breathing problem in which airways narrow, swell and produce extra mucus, leading to difficulty breathing. COPD is a group of lung diseases that mainly include emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of your bronchial tubes). Allergic rhinitis is an inflammation of the nose caused by an allergen, such as pollen, dust, mould, or flakes of skin from certain animals.

Acebrophylline+montelukast is a combination of two medicines: Acebrophylline (bronchodilator) and Montelukast (leukotriene receptor antagonist). Acebrophylline works by relaxing muscles and widening the airways of the lungs. Acebrophylline also has mucoregulating/mucolytic (dissolves thick mucus and helps relieve breathing difficulties) and anti-inflammatory properties. Montelukast blocks the leukotrienes (chemicals released in response when a body comes in contact with an allergen), thereby reducing inflammation and swelling in the nose. It also inhibits bronchoconstriction (narrowing of airways in the lungs that lead to breathing difficulties) and is used in treating asthma and allergic rhinitis. 

Your doctor will advise the dose and duration of the course based on the severity of your disease. The common side effects of Acebrophylline+montelukast include headache, sore throat/cough, vomiting, upset stomach, diarrhoea, heartburn, runny nose, rash, itching, drowsiness, restlessness, abdominal pain (stomach pain), and nasal inflammation. Most of these side effects of Acebrophylline+montelukast do not require medical attention and gradually resolve over time. However, if the side effects are persistent, please reach out to your doctor.

Acebrophylline+montelukast is not intended for use during an acute asthma attack. Your doctor may suggest other medications for your sudden asthma attack. Please inform your doctor in advance if you have heart, liver, kidney and lung diseases, seizures (fits) and depression, phenylketonuria (birth defect caused by the build-up of an amino acid called phenylalanine in the body), hyperthyroidism (overactive thyroid), high blood pressure, stomach ulcers and viral infections before taking Acebrophylline+montelukast. It is advisable to check with your doctor if you are pregnant, currently breastfeeding, or taking any other prescribed or non-prescribed medicines before starting Acebrophylline+montelukast.

Uses of Acebrophylline+montelukast

Chronic Obstructive Pulmonary Disease (COPD), Bronchitis, Asthma, Emphysema and Allergic rhinitis.

Medicinal Benefits

Acebrophylline+montelukast contains Acebrophylline and Montelukast. Acebrophylline is a bronchodilator that works by relaxing muscles and widening the airways of the lungs. Acebrophylline also has muc0-regulating/mucolytic (dissolves thick mucus and helps relieve breathing difficulties) and anti-inflammatory properties. Montelukast blocks leukotrienes (chemicals released in response when a body comes in contact with an allergen) and reduces inflammation and swelling in the nose. It also inhibits bronchoconstriction (narrowing of airways in the lungs that lead to breathing difficulties). Montelukast is also used to relieve exercise-induced bronchospasm (shortness of breath that occurs only during exercise).

Directions for Use

Tablet: Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Acebrophylline+montelukast

  • Headache
  • Sore throat/Cough
  • Vomiting
  • Upset stomach
  • Diarrhoea
  • Heartburn
  • Runny nose
  • Rash, itching
  • Drowsiness
  • Restlessness
  • Abdominal pain (stomach pain)
  • Nasal inflammation

In-Depth Precautions and Warning

Drug Warnings

Do not stop taking this medicine of your own unless advised by your doctor. Before taking Acebrophylline+montelukast, let your doctor know if have heart, liver, kidney and lung diseases, neuropsychiatric disorders like seizures (fits) and depression, phenylketonuria (birth defect caused by the build-up of an amino acid called phenylalanine in the body), hyperthyroidism (overactive thyroid), high blood pressure, stomach ulcers and viral infections. Acebrophylline+montelukast is not intended for use during an acute asthma attack. Therapy with medicines like Montelukast should be cautiously administered in patients with neuropsychiatric disorders. Please seek medical advice if you are pregnant, currently breastfeeding, or taking any other prescribed or non-prescribed medicines before starting Acebrophylline+montelukast.

Drug Interactions

Drug-Drug Interaction: Acebrophylline+montelukast may interact with medicines used to treat gout (allopurinol), antacid (cimetidine), antibiotics (ciprofloxacin, erythromycin, amoxicillin, doxycycline, rifampicin), anti-fungal drugs (thiabendazole), heart-related medicines (isoprenaline), medicines used to lower high blood pressure (diltiazem, verapamil), fluid retention medicines (furosemide), drugs treating fits (phenytoin, phenobarbital), corticosteroids and oral contraceptives.

Drug-Food Interaction: Limit alcohol intake since it may increase the occurrence of side effects like drowsiness.

Drug-Disease Interaction: Before taking Acebrophylline+montelukast, inform your doctor if you have heart, liver, kidney, and lung diseases, seizures (fits) and depression, phenylketonuria, overactive thyroid, high blood pressure, stomach ulcers and viral infections.

Drug-Drug Interactions Checker List:

  • ALLOPURINOL
  • CIMETIDINE
  • CIPROFLOXACIN
  • ERYTHROMYCIN
  • AMOXICILLIN
  • DOXYCYCLINE
  • RIFAMPICIN
  • THIABENDAZOLE
  • ISOPRENALINE
  • DILTIAZEM
  • VERAPAMIL
  • FUROSEMIDE
  • PHENYTOIN
  • PHENOBARBITAL
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      Avoid drinking alcohol while taking Acebrophylline+montelukast to avail the maximum benefits and prevent the worsening of side-effects.

    • Safety Warning

      Pregnancy

      caution

      Acebrophylline+montelukast is recommended to use with caution and under doctor's supervision during pregnancy. Please consult your doctor if you are planning to conceive or already pregnant before starting Acebrophylline+montelukast.

    • Safety Warning

      Breast Feeding

      caution

      There is limited data on how Acebrophylline+montelukast affects breastfeeding. Please consult your doctor before starting Acebrophylline+montelukast.

    • Safety Warning

      Driving

      caution

      Do not drive or operate machinery if you experience drowsiness or difficulty in concentrating while using Acebrophylline+montelukast. Acebrophylline+montelukast may affect your ability to drive. Seek medical attention if the symptoms persist longer.

    • Safety Warning

      Liver

      caution

      Acebrophylline+montelukast should be used with caution in patients with liver diseases. Let your doctor know if you have any history of hepatic impairment before taking Acebrophylline+montelukast.

    • Safety Warning

      Kidney

      caution

      Acebrophylline+montelukast should be used with caution in patients with kidney diseases. Let your doctor know if you have any history of kidney diseases. Your doctor will weigh the benefits and potential risks before prescribing Acebrophylline+montelukast.

    • Safety Warning

      Children

      caution

      Acebrophylline+montelukast is not recommended for use for children less than two years of age. The dose may have to be adjusted by your doctor depending upon the condition of the child's disease and age.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Add ginger to foods or tea as it contains some anti-inflammatory compounds that can relax membranes in the airways and reduce cough, irritation, and swelling in nasal passages.
    • Eat foods rich in potassium, such as tomatoes, bananas, asparagus, oranges, potatoes, avocados, dark leafy greens, and beetroot, as potassium is important for lung function and potassium deficiency may cause breathing problems.
    • Staying hydrated is vital for those with a cough or cold. Drink liquids at room temperature to get relief from runny nose, cough, and sneezing.
    • Do meditation, deep breathing, regular exercise, and try progressive muscle relaxation techniques to get relief from stress.
    • Quit smoking as it may reduce the effectiveness of the Acebrophylline+montelukast and irritate the lungs worsening breathing problems.
    • It is advised to avoid contact with known allergens (allergy-causing agents), such as pollen, dust, etc. Also, certain food items are known to cause allergies to you.
    • Maintain personal hygiene and keep your surroundings clean. 

    Patients Concern

    Disease/Condition Glossary

    Asthma: It is a chronic (long-term) respiratory condition in which airways narrow, swell, and produce extra mucus, leading to difficulty in breathing. The symptoms of asthma include wheezing (whistling sound while breathing), shortness of breath, chest tightness, and cough, especially at night. The symptoms of mild persistent asthma may occur more than 2 times in a week and up to 4 nights in a month whereas, in the case of severe persistent asthma, the symptoms occur several times every day and most nights. The treatment for asthma includes medication, breathing exercises, and self-care. 

    Chronic obstructive pulmonary disease (COPD): It is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of bronchial tubes). The major cause of COPD is smoking tobacco. Also, long-term exposure to fumes and chemicals may lead to COPD. The symptoms include chronic cough, shortness of breath or wheezing (whistle sound while breathing).

    Allergic rhinitis: An inflammation of the nose caused by an allergen, such as pollen, dust, mould, or flakes of skin from certain animals. Its symptoms include itchy, watery eyes, itchy nose, sneezing and runny nose.

    FAQs

    Acebrophylline+montelukast consists of Acebrophylline and Montelukast. Acebrophylline is a bronchodilator that works by relaxing muscles and widening the airways of the lungs. Montelukast is a leukotriene receptor antagonist that blocks leukotrienes (chemicals released in response when a body comes in contact with an allergen) and reduces inflammation and swelling in the nose.

    Please take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule.

    Acebrophylline+montelukast is not recommended for use during a sudden asthma attack since it does not act right away. It is advised to please consult your doctor to prescribe a fast-acting inhaler for rescuing your sudden breathing problems.

    Therapy with leukotriene receptor antagonists like Montelukast may worsen the symptoms of psychotic events in patients with a history of mental illness. Careful administration and monitoring are essential before taking Acebrophylline+montelukast in patients with neuropsychiatric disorders. Please consult your doctor before taking Acebrophylline+montelukast if you have been diagnosed or have a history of mental illness like depression, seizures (fits) etc.

    It is essential to let your doctor know if you have any history of heart, liver, kidney, and lung diseases, neuropsychiatric disorders like seizures (fits) and depression, phenylketonuria (birth defect caused by the build-up of an amino acid called phenylalanine in the body), hyperthyroidism (overactive thyroid), high blood pressure, stomach ulcers and viral infections before taking Acebrophylline+montelukast.

    No, you are advised not to take atenolol while using Acebrophylline+montelukast because atenolol oppose the action of Acebrophylline+montelukast as it narrows the airways and cause breathing difficulty.

    Available Medicines for

    Acebrophylline+montelukast

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