Aceclofenac+paracetamol
About
Aceclofenac+paracetamol belongs to a group of medicines known as 'non-steroidal anti-inflammatory drugs' (NSAID). It is composed of aceclofenac and paracetamol primarily used to reduce pain and inflammation. The pain is an unpleasant sensory and emotional experience associated with actual or potential tissue damage. When you do something that hurts your body, your brain triggers the pain response. Inflammation is a localized physical condition in which part of the body becomes reddened, swollen, hot and often painful, especially as a reaction to injury or infection.
Aceclofenac+paracetamol is composed of two medicines: Aceclofenac (pain reducer) and Paracetamol (fever reducer). Aceclofenac+paracetamol helps in relieving pain from conditions like headache, mild migraine, muscle pain, dental pain, rheumatoid arthritis, ankylosing spondylitis, osteoarthritis and painful menses (periods). Aceclofenac works by inhibiting the effect of chemical messengers like prostaglandins (responsible for producing pain and inflammation). Paracetamol has both analgesic and antipyretic (fever reducer) properties which decreases mild pain and possibly fever.
Aceclofenac+paracetamol should be swallowed whole with liquid, preferably after meals as it helps to prevent any potential gastric irritation the drug might cause when taken empty stomach. Aceclofenac+paracetamol is generally safe to consume. Some people may experience dizziness, nausea (feeling sick), digestion problems (constipation, flatulence, diarrhoea) and skin reactions (like rashes, hives). Most of the side effects of Aceclofenac+paracetamol do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.
Taking more than the daily prescribed dose of Aceclofenac+paracetamol may cause liver damage or allergic reactions like swelling of the mouth, face, throat, difficulty in breathing, skin rash or itching. Gastrointestinal bleeding, ulcer formation may be observed with the use of Aceclofenac+paracetamol, so the doctor may prescribe you the lowest dose available.
Uses of Aceclofenac+paracetamol
Medicinal Benefits
Aceclofenac+paracetamol helps to reduce pain and inflammations caused due to various complications or conditions. It significantly works on providing relief from pain for extended hours. It contains paracetamol which is less irritant to the stomach than other pain killers. Hence, it is well tolerated by patients who have allergy to aspirin or risk of gastro bleeding or ulcer formation. Besides this, it does not affect bleeding time and also helps in reducing fever due to pain or swelling.
Directions for Use
Storage
Side Effects of Aceclofenac+paracetamol
- Dizziness
- Nausea
- Digestion problems (like constipation, flatulence, diarrhoea)
- Increased liver enzymes in the blood (diagnosed through liver function test)
In-Depth Precautions and Warning
Drug Warnings
Taking more than the daily prescribed dose of Aceclofenac+paracetamol may cause liver damage or allergic reactions like swelling of the mouth, face, throat, difficulty in breathing, skin rash or itching. Most of the cases of liver injury are associated with the use of paracetamol. Gastrointestinal bleeding, ulcer formation is commonly observed with the use of Aceclofenac+paracetamol, so the doctor may prescribe you the lowest dose available. Do not take Aceclofenac+paracetamol if you have asthma or allergies to pain killers, heart, kidney and liver conditions. Aceclofenac+paracetamol should not be taken during pregnancy or by breastfeeding mothers as it may affect baby.
Drug Interactions
Drug-Drug Interaction: Aceclofenac+paracetamol interact with cholesterol lowering drugs (cholestyramine), charcoal, medicine to stop vomiting (domperidone, metochlopramide), alcohol, anti HIV drug (zidovudine), blood thinner (warfarin), blood pressure lowering medicine, anti cancer or anti arthritis drug (methotrexate) may lead to drug toxicity or affect the working of Aceclofenac+paracetamol. So, contact the doctor before taking these medicines.
Drug-Food Interaction: No interaction found.
Drug-Disease Interaction: Patient affected with liver disease, bleeding disorder and alcoholism should not take Aceclofenac+paracetamol as it has a risk of causing derangement in liver functions.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeYou are recommended not to consume alcohol along with Aceclofenac+paracetamol as it contains paracetamol which can together damage your liver severely.
Pregnancy
cautionThe safety of this medicine for use during pregnancy is not known. Hence, it is not recommended for use in pregnancy unless considered essential by your doctor.
Breast Feeding
cautionAceclofenac+paracetamol should not be used without consultation with your doctor if you are breast-feeding. It is not known if this medicine passes into breast milk. It is not recommended for use during breast-feeding unless considered essential by your doctor.
Driving
cautionAceclofenac+paracetamol usually causes dizziness, drowsiness and visual disturbances which may affect their ability to drive or operate machinery. Make sure you are not affected before driving or operating machinery.
Liver
cautionAceclofenac+paracetamol to be taken with caution, especially if you have a history of Liver diseases/conditions. The dose may have to be adjusted by your doctor.
Kidney
cautionAceclofenac+paracetamol to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.
Children
unsafeThe safety and efficacy of Aceclofenac+paracetamol in children have not been established. Aceclofenac+paracetamol is not recommended in children.
Habit Forming
Diet & Lifestyle Advise
- Include more glucosamine, chondroitin sulphate, Vitamin D, and calcium-enriched supplements. Besides this, turmeric and fish oils can help in reducing inflammation in the tissue.
- Do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do stretching, and low-impact aerobic exercises like walking on a treadmill, bike riding, and swimming. You can also strengthen your muscle strength by lifting light weights.
- In the chronic condition of arthritis or joint pain try to include fish like salmon, trout, tuna, and sardines. These fishes are enriched with omega-3 fatty acids that minimum level of chemical called cytokines, which ramp up inflammation.
- Your sitting posture is important especially when have pain and inflammation conditions. Try to sit as little as possible, and only for short time (10-15 min). Use back support like a rolled-up towel at the back of your curve to minimize pain. Keep your knees and hips at a right angle. Besides this, you can use a footrest if required.
Special Advise
- The components of Aceclofenac+paracetamol have the tendency of causing stomach upset. Thus, it is recommended to consume Aceclofenac+paracetamol with meals to minimize gastric side effects. If you have a diagnosis of peptic ulcer, Aceclofenac+paracetamol is best avoided unless prescribed by your doctor.
- Paracetamol is a component of Aceclofenac+paracetamol which can cause liver injury when in taken in large doses. Concomitant use of alcohol is best avoided as it aggravates the liver toxicity.
- Although it is generally a safe medicine to use, it should be avoided in patients with kidney disease as Aceclofenac+paracetamol may have an adverse effect on renal functions.
- Use with caution in pregnancy and breastfeeding. Do not self-administer Aceclofenac+paracetamol if you are pregnant or are nursing.
- Although Aceclofenac+paracetamol provides symptomatic relief in conditions like arthritis and may reduce the inflammation caused by these conditions, to achieve best results, it is strongly recommended remaining physically active as much as your condition allows. Adopting a healthy lifestyle coupled with healthy diet containing high proteins, is the mainstay of management of arthritic conditions.
Patients Concern
Disease/Condition Glossary
Pain is an unpleasant sensory and emotional experience associated with actual or potential tissue damage. When you do something that hurts your body, your brain triggers the pain response.
Inflammation is a localized physical condition in which part of the body becomes reddened, swollen, hot and often painful, especially as a reaction to injury or infection.
Arthritis and spondylitis are common lifelong conditions that damage the joints and spines making them stiff and painful.
FAQs
No, Aceclofenac+paracetamol does not cure Rheumatoid arthritis but instead, it helps in reducing the pain and inflammation caused by it as it a pain killer.
Yes, Aceclofenac+paracetamol is may cause nausea or vomiting in some people. In order to avoid the same, you should take Aceclofenac+paracetamol with milk or food. In case you are still experiencing excessive nausea while consuming Aceclofenac+paracetamol, speak with your doctor right away.
No, do not suddenly stop taking Aceclofenac+paracetamol. If you want to stop taking this medicine, consult your doctor and he might gradually reduce the dose to avoid an unwanted increase in pain or inflammation.
No, Aceclofenac+paracetamol should ideally not be taken for stomach pain without consulting a physician. This medication can increase the secretion of stomach acid, which may worsen gastritis or an unknown underlying stomach ulcer.
Patients with mild to moderate renal impairment should be kept under surveillance. The lowest effective dose should be used and renal function monitored regularly. Effects on renal function are usually reversible on withdrawal of Aceclofenac+paracetamol.
