ACECLOFENAC+RABEPRAZOLE

Do not take ACECLOFENAC+RABEPRAZOLE if you are allergic to ACECLOFENAC+RABEPRAZOLE, have severe heart failure, suffered bleeding problems (such as bleeding from the stomach or bowels while taking any pain killers) or liver or kidney problems, have suffered bleeding problems and clotting problems. Inform your doctor before taking ACECLOFENAC+RABEPRAZOLE if you have or had disorders of the stomach, blood circulation problems to the brain, asthma, porphyria (a disorder in the formation of red blood pigment), diabetes, high blood pressure, systemic lupus erythematosus (an autoimmune condition that causes joint pain, fever and skin rashes), colitis or Crohn’s disease (conditions causing swelling of the bowel, diarrhoea, bowel pain, vomiting and weight loss); if you are recovering from major surgery or if you are elderly. Do not take ACECLOFENAC+RABEPRAZOLE if you are pregnant or breastfeeding unless prescribed. ACECLOFENAC+RABEPRAZOLE contains Aceclofenac which should not be used during the last three months of pregnancy. ACECLOFENAC+RABEPRAZOLE may be excreted in breastmilk. Therefore, avoid breastfeeding and consult a doctor. ACECLOFENAC+RABEPRAZOLE should not be given to children as safety has not been established. ACECLOFENAC+RABEPRAZOLE can cause drowsiness and dizziness, so drive only if you are alert. Avoid consuming alcohol with ACECLOFENAC+RABEPRAZOLE as it could lead to increased drowsiness and increase the risk of stomach bleeding. Do not take other NSAIDs for pain relief or ACECLOFENAC+RABEPRAZOLE unless prescribed. Prolonged intake of PPIs or proton pump inhibitors like Rabeprazole may cause brittle bones so intake of Vitamin D and calcium can be additionally given by your doctor while using ACECLOFENAC+RABEPRAZOLE. 

Drug-Drug Interactions: ACECLOFENAC+RABEPRAZOLE interact with other painkillers (aspirin, ibuprofen, acetaminophen, oxycodone, tramadol, naproxen, celecoxib, etoricoxib), blood thinners (clopidogrel, heparin, warfarin), medicines used to treat heart diseases (digoxin), diuretics (furosemide, amiloride), antibiotics (ciprofloxacin, norfloxacin, moxifloxacin, ciprofloxacin, ofloxacin, levofloxacin), antihypertensive (enalapril, valsartan, telmisartan, losartan, candesartan, propranolol, enalapril, lisinopril, methyldopa, clonidine, moxonidine), antidiabetics (glibenclamide, gliclazide, tolbutamide), antidepressants (fluvoxamine, paroxetine, citalopram, escitalopram, sertraline, fluoxetine), steroids (hydrocortisone, prednisolone), immunosuppressants (ciclosporin, tacrolimus), anti-HIV (zidovudine).

Drug-Food Interactions: Avoid consumption of alcohol while taking ACECLOFENAC+RABEPRAZOLE as it might cause increased dizziness and risk of stomach bleeding.

Drug-Disease Interactions: ACECLOFENAC+RABEPRAZOLE may have interactions with asthma, heart, liver, and kidney problems, low vitamin B12 (anaemia), high blood pressure, high cholesterol, systemic lupus erythematosus (an autoimmune condition that causes joint pain, fever and skin rashes), porphyria (a disorder in the formation of red blood pigment), colitis or Crohn’s disease (conditions causing swelling of the bowel, diarrhoea, bowel pain, vomiting and weight loss).

• Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
• Performing yoga may also help in improving joint flexibility and pain management.
• Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
• Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.
• Follow heat or cold therapy, apply a cold or hot compress on the joints for 15-20minutes regularly.
• Acupuncture, massage and physical therapy may also be helpful.
• Foods containing flavonoids such as soy, berries, broccoli, grapes and green tea help in reducing inflammation.
• Include high fibre-containing foods, berries, cherries, leafy green veggies, and black peppers in your meal. These foods are full of antioxidants, calcium, and vitamin B12 that can help cope with the long-term effects of the medicine. Fermented dairy products like miso, sauerkraut, and kimchi contain probiotics that help in the prevention of excess stomach acid production.
• Avoid intake of acid or heartburn triggering foods or drinks like onions, peppermint, chocolate, caffeinated beverages, citrus fruits or juices, tomatoes, and high-fat and spicy foods.
• Avoid smoking and alcohol consumption.

• Prolonged use of Aceclofenac in ACECLOFENAC+RABEPRAZOLE may be associated with a small increased risk of heart attack known as myocardial infarction, so if you have any heart-related problems before using ACECLOFENAC+RABEPRAZOLE, let your doctor know about this. 
• ACECLOFENAC+RABEPRAZOLE contains Aceclofenac which should not be used during the last three months of pregnancy. ACECLOFENAC+RABEPRAZOLE should not be used by anyone less than 18 years of age. 
• ACECLOFENAC+RABEPRAZOLE contains Rabeprazole which may cause kidney problems in rare cases, so if you are urinating less than usual, or have blood coming in your urine, let your doctor know about this.
• Prolonged intake of PPIs or proton pump inhibitors like Rabeprazole may cause diarrhoea, autoimmune disease (lupus) and brittle bones. So tell your doctor if you have these symptoms.