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Thiocolchicoside+aceclofenac+paracetamol

About Thiocolchicoside+aceclofenac+paracetamol

Aceclofenac+paracetamol+thiocolchicoside is a combination medicine used to relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, muscle pain, bone and joint pain. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Muscle spasm is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable. Arthritis is tenderness and swelling in the joints.

Aceclofenac+paracetamol+thiocolchicoside contains Thiocolchicoside (muscle relaxant), Aceclofenac (NSAID), and Paracetamol (Analgesic). Thiocolchicoside works on the centers of the spinal cord and brain. This helps relieve muscle stiffness and improves muscle movements. Aceclofenac and Paracetamol work by blocking the effect of chemical messengers that cause pain and inflammation.  Together, Aceclofenac+paracetamol+thiocolchicoside helps in relieving pain due to muscle spasms.

You are advised to take Aceclofenac+paracetamol+thiocolchicoside for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side-effects such as nausea, vomiting, stomach pain, loss of appetite, heartburn, and diarrhoea. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Consult your doctor if you are pregnant or breastfeeding. Aceclofenac+paracetamol+thiocolchicoside may cause drowsiness and dizziness, so drive with caution. Aceclofenac+paracetamol+thiocolchicoside should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol with Aceclofenac+paracetamol+thiocolchicoside as it could lead to increased drowsiness and dizziness; it might also increase the risk of stomach bleeding. Keep your doctor informed about your health condition and medicines to rule out any side-effects/interactions.

Uses of Thiocolchicoside+aceclofenac+paracetamol

Pain and inflammation associated with musculoskeletal and joint disorders.

Medicinal Benefits

Aceclofenac+paracetamol+thiocolchicoside is a combination of three drugs, namely: Thiocolchicoside, Aceclofenac, and Paracetamol. Aceclofenac+paracetamol+thiocolchicoside is used to relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, muscle pain, bone and joint pain. Aceclofenac+paracetamol+thiocolchicoside increases the pain threshold and blood flow across the skin. Thiocolchicoside is a muscle relaxant which works on the centres of the spinal cord and brain. This helps relieve muscle stiffness and improves muscle movements. Aceclofenac and Paracetamol are analgesics that block the effect of a chemical messenger known as cyclo-oxygenase (COX) enzymes that make another chemical, prostaglandins. These prostaglandins are produced at injury sites and cause pain and swelling. By blocking COX enzymes' effect, lesser prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. Together, Aceclofenac+paracetamol+thiocolchicoside helps in relieving pain due to muscle spasms.

Directions for Use

Swallow Aceclofenac+paracetamol+thiocolchicoside as a whole with a glass of water; do not chew, or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Thiocolchicoside+aceclofenac+paracetamol

  • Nausea
  • Vomiting
  • Stomach pain
  • Diarrhoea
  • Loss of appetite
  • Heartburn

Drug Warnings

Do not take Aceclofenac+paracetamol+thiocolchicoside if you are allergic to any of its contents; if you have/had severe heart problems, stomach ulcer or perforation, and bleeding problems such as bleeding from the stomach, intestine or brain, bypass surgery, heart attack, blood circulation problems, or inflammation of intestines. Inform your doctor if you have high blood pressure, heart problems, high cholesterol, diabetes, asthma, inflammatory bowel disease, liver or kidney problems. Consult your doctor if you are pregnant or breastfeeding. Aceclofenac+paracetamol+thiocolchicoside may cause drowsiness and dizziness, so drive only if you are alert. Aceclofenac+paracetamol+thiocolchicoside is not recommended for children as safety and effectiveness have not been established. Avoid consuming alcohol with Aceclofenac+paracetamol+thiocolchicoside as it could lead to increased drowsiness and increased risk of stomach bleeding. Stop taking Aceclofenac+paracetamol+thiocolchicoside and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools. Do not take any other NSAIDs for pain relief along with Aceclofenac+paracetamol+thiocolchicoside unless prescribed.

Drug Interactions

Drug-Drug Interactions: Inform your doctor if you are taking painkillers (aspirin, ibuprofen, naproxen, celecoxib, etoricoxib), anti-depressants (citalopram, escitalopram, fluoxetine, fluvoxamine, paroxetine, sertraline, lithium), cardiac glycoside (digoxin), anti-hypertensives (enalapril, lisinopril, losartan, candesartan, hydralazine, methyldopa, clonidine, moxonidine, propranolol), antibiotics (ciprofloxacin, ofloxacin, levofloxacin moxifloxacin), diuretics (furosemide, amiloride hydrochloride), blood thinners (warfarin, heparin, clopidogrel), anti-rheumatoid (methotrexate), steroids (mifepristone), glucocorticoids (hydrocortisone, prednisolone), immunosuppressants (ciclosporin, tacrolimus), anti-HIV (zidovudine), anti-diabetic (glibenclamide, gliclazide, tolbutamide).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform your doctor if you have/had a stomach ulcer or perforation, bleeding problems, bypass surgery, heart attack, blood circulation problems, inflammation of intestines, anaemia, heart, kidney or liver problems.

Drug-Drug Interactions Checker List:

  • ASPIRIN
  • IBUPROFEN
  • NAPROXEN
  • CELECOXIB
  • ETORICOXIB
  • CITALOPRAM
  • ESCITALOPRAM
  • FLUOXETINE
  • FLUVOXAMINE
  • PAROXETINE
  • SERTRALINE
  • LITHIUM
  • DIGOXIN
  • ENALAPRIL
  • LISINOPRIL
  • LOSARTAN
  • CANDESARTAN
  • HYDRALAZINE
  • METHYLDOPA
  • CLONIDINE
  • MOXONIDINE
  • PROPRANOLOL
  • CIPROFLOXACIN
  • OFLOXACIN
  • LEVOFLOXACIN
  • MOXIFLOXACIN
  • FUROSEMIDE
  • AMILORIDE
  • WARFARIN
  • HEPARIN
  • CLOPIDOGREL
  • METHOTREXATE
  • MIFEPRESTONE
  • HYDROCORTISONE
  • PREDNISOLONE
  • CYCLOSPORINE
  • TACROLIMUS
  • ZIDOVUDINE
  • GLIBENCLAMIDE
  • GLICLAZIDE
  • TOLBUTAMIDE
  • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      Avoid consumption of alcohol while taking Aceclofenac+paracetamol+thiocolchicoside as it may cause increased drowsiness. It can also increase the risk of stomach bleeding.

    • Safety Warning

      Pregnancy

      caution

      Please consult your doctor if you are pregnant; your doctor will prescribe Aceclofenac+paracetamol+thiocolchicoside only if the benefits outweigh the risks.

    • Safety Warning

      Breast Feeding

      caution

      Consult your doctor if you are breastfeeding; your doctor will decide whether Aceclofenac+paracetamol+thiocolchicoside can be taken by breastfeeding mothers or not.

    • Safety Warning

      Driving

      caution

      Aceclofenac+paracetamol+thiocolchicoside may cause dizziness and drowsiness. Do not drive or operate machinery unless you are alert.

    • Safety Warning

      Liver

      caution

      Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

    • Safety Warning

      Kidney

      caution

      Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

    • Safety Warning

      Children

      unsafe

      Aceclofenac+paracetamol+thiocolchicoside should not be given to children as safety and effectiveness were not established.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Exercising regularly helps in muscle stretching so that they are less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
    • Massages can also be helpful.
    • Avoid freezing and hot temperatures.
    • Avoid wearing tight-fitting clothes, instead, wear loose garments.
    • Rest well, and get plenty of sleep.
    • To avoid developing pressure sores, change your position every two hours.
    • Hot or cold therapy can help treat muscle spasms. Apply an ice-pack or hot-pack on the muscle for 15-20minutes.
    • Stay hydrated, drink plenty of water.

    Patients Concern

    Disease/Condition Glossary

    Pain: Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Pain may be dull or sharp; it might be constant or may come and go. The tolerance level of pain might vary from person to person. Pain can be generalised (overall body aches) or localised (affecting a specific area of the body). The common causes of pain include headache, muscle strain, cramps, cuts, bone fractures, and arthritis.

    Osteoarthritis: It is a joint disease in which the two ends of the joints come together due to the breakdown of a protective covering called cartilage. Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness. Symptoms include pain, stiffness, inflammation and tenderness.

    Rheumatoid arthritis: It is an auto-immune disease (the body's immune system attacks its tissue), leading to joint pain and damage. Symptoms of rheumatoid arthritis include pain, swelling, stiffness, deformities and loss of joint function.

    Ankylosing spondylitis: It causes pain and stiffness in the spine. The pain generally starts in the lower back and can spread to the neck, damaged joints, or other body parts. Ankylosing spondylitis includes decreased flexibility which usually leads to a hunched-forward posture, pain in the back and joints.

    FAQs

    Aceclofenac+paracetamol+thiocolchicoside contains Thiocolchicoside, Aceclofenac, and Paracetamol. Thiocolchicoside works on the centres of the spinal cord and brain. This helps relieve muscle stiffness and improves muscle movements. Aceclofenac and Paracetamol work by blocking the chemical messengers that cause pain and inflammation at the injured or damaged site.

    Aceclofenac+paracetamol+thiocolchicoside is used to reduce and relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. Arthritis is tenderness and swelling in the joints.

    Diarrhoea might be a side-effect of Aceclofenac+paracetamol+thiocolchicoside. Drink enough fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or experience severe diarrhoea consult your doctor. Do not take anti-diarrheal medicine on your own.

    Aceclofenac+paracetamol+thiocolchicoside should not be taken for longer durations unless prescribed by the doctor. If Aceclofenac+paracetamol+thiocolchicoside has been prescribed for longer durations, regular monitoring of kidney function, liver function, and blood count is advised, particularly in elderly patients.

    Aceclofenac+paracetamol+thiocolchicoside may cause abnormal chromosome numbers in the sperm cells, which might damage sperm. This might cause problems with male fertility. Consult your doctor before taking Aceclofenac+paracetamol+thiocolchicoside if you plan to become a father.

    Dry mouth could be a side-effect of Aceclofenac+paracetamol+thiocolchicoside. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent drying of mouth.

    Available Medicines for

    Thiocolchicoside+aceclofenac+paracetamol

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