Adapalene+allantoin+clindamycin
About Adapalene+allantoin+clindamycin
Adapalene+allantoin+clindamycin belongs to the class of dermatological preparations called 'antiacne' used to treat acne (pimples). Also, Adapalene+allantoin+clindamycin helps treat or prevent dry, scaly, itchy skin and rough and minor skin irritations. Acne is a common skin condition and occurs when hair follicles are blocked with dead skin cells and oil. The acne-causing bacteria feeds on sebum (natural oil produced by skin), causing redness and swelling.
Adapalene+allantoin+clindamycin is a combination of three medicines, namely: Adapalene (human-made vitamin A), Clindamycin (antibiotic) and Allantoin (moisturiser). Adapalene (human-made vitamin A) works by loosening the cells in the skin’s surface and unblocks pores by reducing oil production in the skin, thereby reducing pimples formation of whiteheads and blackheads on the skin's surface. Clindamycin belongs to the class of antibiotics that inhibits the production of essential proteins necessary for bacteria to grow, multiply and increase in numbers. Allantoin is a moisturising agent that works, forming an oily layer on the top of the skin that traps in the water. Thereby moisturising the outermost layer of skin and making it smoother and softer. Also, it breaks down a protein known as keratin (that forms part of skin structure) and removes dead skin cells and softens skin. Altogether it stops or slows down the growth of bacteria and prevents the growth of acne.
Adapalene+allantoin+clindamycin is only for external use. Use Adapalene+allantoin+clindamycin as prescribed by the doctor. Avoid contact of Adapalene+allantoin+clindamycin with nose, ears, mouth or eyes. In case Adapalene+allantoin+clindamycin comes in contact with these areas accidentally, rinse with warm water thoroughly. Your doctor will advise you how often you take Adapalene+allantoin+clindamycin based on your medical condition. In some cases, you may experience skin peeling, dry skin, irritation, redness, oily skin, itching or a burning sensation at the site of application. Most of these side effects of Adapalene+allantoin+clindamycin do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
If you are known to be allergic to Adapalene+allantoin+clindamycin or any other medicines, please tell your doctor. Do not apply Adapalene+allantoin+clindamycin to cuts, open wounds, broken, sunburnt or sensitive skin areas. Avoid sun exposure while using Adapalene+allantoin+clindamycin as it may make the skin more sensitive to sunlight and cause sunburn. Wear protective clothing and use sunscreen while going out to protect your skin from sunburn. If you are pregnant or breastfeeding, please inform your doctor before taking Adapalene+allantoin+clindamycin. Do not apply Adapalene+allantoin+clindamycin in large amounts or use for a long time than prescribed as it does not give quick or better results but increases the risk of side effects such as redness, irritation, skin peeling or discomfort. If you have intestine problems or eczema, please inform your doctor before using Adapalene+allantoin+clindamycin. Adapalene+allantoin+clindamycin is not approved for use in children younger than 12 years old.
Uses of Adapalene+allantoin+clindamycin
Medicinal Benefits
Adapalene+allantoin+clindamycin is a combination of three drugs, namely, Adapalene, Allantoin, and Clindamycin, used to treat acne (pimples). Adapalene is a retinoid (human-made vitamin A) that loosens the cells on the skin’s surface and unblocks pores by reducing oil production in the skin. Thereby decreasing pimples, spots, whiteheads and blackheads. Also, Adapalene increases the production of new skin cells and helps in the natural exfoliation (removal of dead skin cells) of the skin's outer layers. Clindamycin is a broad-spectrum antibiotic that acts against aerobic (grows in the presence of oxygen) and anaerobic (grows in the absence of oxygen) gram-negative and gram-positive bacteria. Clindamycin inhibits the production of essential proteins necessary for bacteria to grow, multiply and increase in numbers. Allantoin is a moisturising agent that forms an oily layer on the top of the skin and traps it in the water. Thereby moisturising the outermost layer of skin and makes it smoother and softer. Also, it breaks down a protein known as keratin (that forms part of skin structure) and removes dead skin cells and softens skin. Altogether, it stops or slows down bacteria's growth, causing acne and heals the skin by reducing swelling and redness.
Directions for Use
Storage
Side Effects of Adapalene+allantoin+clindamycin
- Skin peeling
- Dry skin
- Irritation
- Redness
- Oily skin
- Itching or burning sensation at the site of application
Drug Warnings
If you are known to be allergic to Adapalene+allantoin+clindamycin or any other medicines, please tell your doctor. Do not apply Adapalene+allantoin+clindamycin to cuts, open wounds, broken, sunburnt or sensitive skin areas. Avoid sun exposure while using Adapalene+allantoin+clindamycin as it may make the skin more sensitive to sunlight and cause sunburn. Wear protective clothing and use sunscreen while going out to protect your skin from sunburn. If you are pregnant or breastfeeding, please inform your doctor before taking Adapalene+allantoin+clindamycin. Do not apply Adapalene+allantoin+clindamycin in large amounts or use for a long time than prescribed as it does not give quick or better results but increases the risk of side effects such as redness, irritation, skin peeling or discomfort. If you have intestine problems or eczema, please inform your doctor before taking Adapalene+allantoin+clindamycin. Adapalene+allantoin+clindamycin is not approved for use in children younger than 12 years old.
Drug Interactions
Drug-Drug Interactions: Adapalene+allantoin+clindamycin may interact with vitamin A-related drugs known as retinoids (isotretinoin), salicylic acid (common in topical acne medicines or skin cleansers). Photosensitizing agents (aminolevulinic acid, methoxsalen), erythromycin (taken orally or applied to the skin).
Drug-Food Interactions: No interactions found.
Drug-Disease Interactions: If you have colitis or enteritis (inflammation of your intestines) or eczema, please inform your doctor before taking Adapalene+allantoin+clindamycin.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionThe interaction of Adapalene+allantoin+clindamycin with alcohol is unknown. Please consult a doctor before consuming alcohol while using Adapalene+allantoin+clindamycin.
Pregnancy
cautionThe safety of Adapalene+allantoin+clindamycin in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks the benefits outweigh the risks.
Breast Feeding
cautionDo not apply Adapalene+allantoin+clindamycin on the breast. You are advised to breastfeed only if the doctor thinks benefits are greater than risks.
Driving
safe if prescribedAdapalene+allantoin+clindamycin usually does not affect your ability to drive or operate machinery.
Liver
safe if prescribedIf you have any concerns regarding the use of Adapalene+allantoin+clindamycin in patients with Liver problems, please consult a doctor.
Kidney
safe if prescribedIf you have any concerns regarding the use of Adapalene+allantoin+clindamycin in patients with kidney problems, please consult a doctor.
Children
unsafeAdapalene+allantoin+clindamycin is not recommended for children as the safety and effectiveness were not established.
Habit Forming
Diet & Lifestyle Advise
- Avoid sun exposure while using Adapalene+allantoin+clindamycin as it may make the skin more sensitive to sunlight and cause sunburn. Try to wear protective clothing and use sunscreen while going out to protect your skin from sunburn.
- Regular exercise can improve your mood and self-esteem though it doesn’t clear acne. Take a shower immediately after finishing exercise, as sweat may irritate acne.
- Do regular hair wash regularly and avoid hair falling across the face.
- Remove the makeup completely before going to bed.
- Avoid using products that may cause skin irritation, such as harsh soaps, skin cleansers, shampoos, hair removers or waxes, hair colouring or permanent chemicals, detergents and rough fabrics.
Special Advise
- Please inform your doctor if your infected skin area does not improve after 4 weeks of treatment.
- Limit your time in sunlight exposure and avoid skin tanning booths and sunlamps. Also, use sunscreen lotion (or SPF) and wear protective clothing when outdoors.
- You are advised to apply any other lotions, creams or ointments, including cosmetics and moisturizers, after 30 minutes of applying Adapalene+allantoin+clindamycin, as using both simultaneously may reduce the effectiveness of Adapalene+allantoin+clindamycin.
- Avoid contact of Adapalene+allantoin+clindamycin with nose, mouth, eyes or ears. In case Adapalene+allantoin+clindamycin comes in contact with these areas accidentally, rinse with water.
- Do not squeeze, pop or pick spots, as it may worsen them and cause permanent scarring.
Patients Concern
Disease/Condition Glossary
Acne (pimples): It is a common skin condition that occurs when hair follicles are blocked with dead skin cells and oil, causing pimples, whiteheads and blackheads. Acne affects people of all ages but is most common among teenagers. Acne symptoms include pus-filled pimples, uninflamed (not swollen) blackheads, red, large and tender bumps. The treatment for acne includes certain creams, cleansers and antibiotics.
FAQs
Yes, Adapalene+allantoin+clindamycin may cause photosensitivity (increased skin sensitivity to sunlight) in the treated areas. Therefore, avoid or limit exposure to sunlight and sunlamps. You are advised to use a sunscreen and wear protective clothing while going out to prevent sunburn.
No, Adapalene+allantoin+clindamycin is not recommended for eczema (itchy, cracked, swollen or rough skin) patients as it may increase the risk of severe irritation. Therefore, if you are suffering from eczema, inform your doctor before using Adapalene+allantoin+clindamycin.
Yes, Adapalene+allantoin+clindamycin may cause skin irritation or sensitivity as a side effect. However, if the irritation persists or worsens, stop using Adapalene+allantoin+clindamycin and consult a doctor.
You are advised to use other acne products with Adapalene+allantoin+clindamycin cautiously as some products may increase side effects. It is recommended to use Adapalene+allantoin+clindamycin at night and other products in the morning. However, please consult a doctor before using any other medicines or products with Adapalene+allantoin+clindamycin.
No, you are not recommended to stop taking Adapalene+allantoin+clindamycin without consulting your doctor as it may worsen the condition or cause recurring symptoms. Therefore, take Adapalene+allantoin+clindamycin for as long as your doctor has prescribed it and if you experience any difficulty while taking Adapalene+allantoin+clindamycin, please consult your doctor.
Adapalene+allantoin+clindamycin may cause skin itching at the site of application as a temporary side effect. However, if the itching persists or worsens, please consult a doctor.
You are not recommended to cover the treated area of skin with bandages or dressings unless advised by your doctor as it may increase the risk of side effects.
You are recommended to use Adapalene+allantoin+clindamycin for as long as your doctor has prescribed it. However, if the condition persists or worsens within 8 to 12 weeks of treatment with Adapalene+allantoin+clindamycin, please consult a doctor.