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Albendazole+ivermectin

About

Albendazole+ivermectin belongs to the class of medications called ‘antihelmintic’ used to treat parasitic worm infections. Parasitic worm infections are intestinal worm infections that are caused by the ingestion of contaminated food and water. Albendazole+ivermectin can be used to treat infections caused by roundworms, hookworms, threadworms, whipworms, pinworms, flukes, and other parasites. 

Albendazole+ivermectin contains ‘albendazole’ and ‘ivermectin’, which work by keeping the worm from taking glucose and depleting its energy levels, leading to its immobilization. Ivermectin can kill the parasites by acting on the nervous system. It starves the worms by inducing paralysis, consequently leading them to death.

You should take this medicine as prescribed by your doctor. The common side-effects of Albendazole+ivermectin are stomach pain, nausea, vomiting, headache, dizziness, decrease in white blood cell count (leucopenia), vision problems, confusion, weakness, and difficulty walking. Inform your doctor if any of these side effects persist or get worsen.

You should not take Albendazole+ivermectin if you are allergic to ‘albendazole’, ‘ivermectin’, or any other ingredients present in it. Before taking Albendazole+ivermectin, inform your doctor if you have a medical history of meningitis, African sleeping sickness (an infection caused by the bite of tsetse fly in African countries), or illness that weakens the immune system HIV. It may make you more prone to infections, so maintain proper hygiene. It may cause dizziness, so refrain from activities that require you to stay alert.

Uses of Albendazole+ivermectin

Parasitic worm infections.

Medicinal Benefits

Albendazole+ivermectin contains ‘Albendazole’ and ‘Ivermectin’, which belong to the class of medications called ‘antihelmintic’. It is a broad-spectrum antibiotic used in the treatment of parasitic infections. It can kill the disease-causing worms and stop the spread of infection effectively. Albendazole interrupts the absorption of glucose by the worm leading to energy depletion. Ivermectin acts by paralyzing the worms, consequently leading them to death.

Directions for Use

Tablet: It is advised to swallow the tablet as a whole with water, so do not crush, break, or chew it. The dose of the medicine is determined by your doctor based on your condition. Chewable tablet: Chew the tablet completely and swallow. Do not swallow it as a whole. Syrup/suspension: Shake the bottle well before each use. Take the prescribed dose of medicine with a marked measuring spoon, oral syringe, or medicine cup, followed by water. It may cause a bitter or metallic taste, so avoid taking it at the same time as food or other drinks.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Albendazole+ivermectin

  • Stomach pain
  • Nausea
  • Vomiting
  • Headache
  • Dizziness
  • Decrease in white blood cell count (leucopenia)
  • Vision problems
  • Confusion
  • Weakness
  • Difficulty walking

In-Depth Precautions and Warning

Drug Warnings

Albendazole+ivermectin may cause suppression of the bone marrow and cause anaemia. Inform your doctor if you have/had liver disease; if you have any surgery, including dental surgery. Consult your doctor immediately if you experience seizures, extreme tiredness, behaviour changes, blurred vision, trouble walking, or neck pain while taking Albendazole+ivermectin. Consult your doctor if you notice unusual bleeding or bruising as you may bleed or bruise easily while taking Albendazole+ivermectin. It may cause orthostatic hypotension (dizziness upon rising up quickly), so avoid standing up too quickly from a sitting or lying position.

Drug Interactions

Drug-Drug Interactions: Albendazole+ivermectin may interact with sedatives (phenobarbital and butalbital), anti-anxiety drugs (clonazepam, clozapine, and lorazepam), narcotic (sodium oxybate), a medication used to treat epilepsy (valproic acid), anthelmintic (praziquantel), corticosteroid (dexamethasone), antacid (cimetidine), anti-asthma (theophylline),

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: Albendazole+ivermectin should be used with caution in patients with myelosuppression (bone marrow suppression), hepatobiliary dysfunction (liver and biliary disease), neurological disorder, meningitis (inflammation of the membranes of brain), sleeping sickness, HIV, and kidney dysfunction.

Drug-Drug Interactions Checker List:

  • PHENOBARBITAL
  • BUTALBITAL
  • CLONAZEPAM
  • LORAZEPAM
  • SODIUM OXYBATE
  • VALPROIC ACID
  • PRAZIQUANTEL
  • DEXAMETHASONE
  • CIMETIDINE
  • THEOPHYLLINE
  • CLOZAPINE
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      Albendazole+ivermectin may interact with alcohol and worsen the condition.

    • Safety Warning

      Pregnancy

      unsafe

      Albendazole+ivermectin is a category C drug and may cause toxic effects to the unborn baby. So, your doctor may prescribe this medicine if the benefits outweigh the risks.

    • Safety Warning

      Breast Feeding

      caution

      Albendazole+ivermectin may get excreted in the breast milk. So, your doctor may advise you to stop breastfeeding while taking this medicine.

    • Safety Warning

      Driving

      caution

      Albendazole+ivermectin may cause dizziness and vision problems, so refrain from driving or operating heavy machinery while using this medicine.

    • Safety Warning

      Liver

      caution

      Albendazole+ivermectin should be used with caution in patients with liver diseases. Dose adjustments may be necessary.

    • Safety Warning

      Kidney

      caution

      Albendazole+ivermectin should be used with caution in patients with kidney diseases. Dose adjustments may be necessary.

    • Safety Warning

      Children

      safe if prescribed

      Albendazole+ivermectin should be used in children only if clinically needed.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Wash your hands regularly with soap and water, especially after using the toilet and while eating.
    • Avoid eating raw fish and meat.
    • Thoroughly cook meat before eating.
    • Wash all fruits and vegetables properly before consuming them.
    • Wash or reheat food that has been around for a long time.
    • Avoid contact with soil that may be contaminated with faeces.
    • Avoid foods that have been kept open in the markets as they can be contaminated.
    • Drink boiled and purified water.

    Special Advise

    Get up slowly and rest your feet on the floor for a few minutes before standing up to avoid orthostatic hypotension.

    Patients Concern

    Disease/Condition Glossary

    Parasitic worm infections: Parasitic worms are also called intestinal worms or helminths. They live in and feed on the hosts leading to weakness and diseases. Common types of intestinal worms are roundworms and flatworms such as tapeworms and flukes. Worm infections could occur due to consumption of contaminated water, food, or soil, contact with contaminated faeces, poor sanitization, or poor hygiene. Symptoms of worm infections include abdominal pain, diarrhoea, nausea, vomiting, gas, bloating, fatigue, unexplained weight loss, and dysentery (bloody stools).

    FAQs

    Albendazole+ivermectin is a combination of two antihelmintic drugs 'albendazole' and 'ivermectin'. It is used to treat a wide range of parasitic infections. It kills the parasite by keeping it from utilizing glucose and depleting its energy levels. It also paralyzes the insect, thereby leading it to death.

    Albendazole+ivermectin usually improves your symptoms within 2 to 3 days after taking this medicine. however, you have to complete the course of therapy as prescribed by your doctor. If there is no improvement in your condition even after completion of the course, consult your doctor immediately.

    Albendazole+ivermectin may cause vision problems such as blurred vision. Consult your doctor if your vision problem affects your daily activities.

    Albendazole+ivermectin is not an antibiotic. It is an antihelmintic medication used to treat parasitic worm infections in the stomach and intestine.

    You may require regular monitoring of blood cell count and liver function during treatment with Albendazole+ivermectin. Albendazole+ivermectin might increase the chances of getting an infection, so maintain proper hygiene, and try to stay away from people with infections, flu, or cold.

    Common symptoms of intestinal worms are stomach (abdominal pain); diarrhoea, nausea, vomiting; gas formation, bloating; fatigue and unexplained weight.

    Available Medicines for

    Albendazole+ivermectin

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