Alfuzosin+solifenacin
About
Alfuzosin+solifenacin belongs to a class of drug known as genitourinary tract agent primarily used to treat benign prostatic hyperplasia (overgrowth of the prostate gland, a gland situated between the bladder and penis). Benign prostatic hyperplasia is a common illness as men get older. An inflamed prostate gland can cause unpleasant urinary symptoms, like preventing the urine flow out of the bladder. It can also cause urinary tract, bladder, or kidney problems.
Alfuzosin+solifenacin is a combination of two medicines: Alfuzosin (alpha-blockers) and Solifenacin (antimuscarinic). Alfuzosin works by blocking the action of alpha-1 receptors and causes smooth muscle relaxation in the bladder and prostate (a walnut-sized gland located between the bladder and the penis). Solifenacin works by inhibiting contraction of the smooth muscle wall surrounding the bladder, resulting in decrease bladder activity. This helps to control the release of urine and helps reduce your symptoms. Collectively, both of them improve the symptoms of Benign Hyperplasia Prostate (BPH).
Take Alfuzosin+solifenacin as prescribed by your doctor. You are advised to take Alfuzosin+solifenacin for as long as your doctor has prescribed it for you depending on your medical conditions. You may experience dizziness, headache, tiredness, dryness in the mouth, blurred vision, constipation, flushing (sense of warmth in the face, ears, neck and trunk). Most of these side effects of Alfuzosin+solifenacin do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.
To treat your condition effectually, continue taking Alfuzosin+solifenacin for as long as your doctor has prescribed it. Try not to stop taking it on your own. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Alfuzosin+solifenacin. Women or children should not take Alfuzosin+solifenacin. Avoid consumption of alcohol as it may increase the side effects like dizziness and low blood pressure. If you take Alfuzosin+solifenacin with any antihypertensive medicine, your blood pressure could suddenly drop to s life-threatening level. So avoid intake of Alfuzosin+solifenacin with antihypertensive drugs.
Uses of Alfuzosin+solifenacin
Medicinal Benefits
Alfuzosin+solifenacin is a combination of two drugs, namely; Alfuzosin and Solifenacin used to treat the symptoms of benign prostatic hyperplasia (BPH) in adults with an enlarged prostate gland. Alfuzosin belongs to a class of alpha-1 adrenergic receptors (located in prostate and bladder) blocker that works by blocking the action of alpha-1 receptors and causes smooth muscle relaxation in the bladder and prostate (a walnut-sized gland located between the bladder and the penis). Solifenacin belongs to a class of antimuscarinic (inhibiting the action of acetylcholine (chemical substance) that works by inhibiting contraction of the smooth muscle wall surrounding the bladder, resulting in a decrease in bladder activity. This helps to control the release of urine and helps reduce your symptoms. Alfuzosin+solifenacin reduces the BPH symptoms and improves your ability to urinate.
Directions for Use
Storage
Side Effects of Alfuzosin+solifenacin
- Dizziness
- Headache
- Tiredness
- Dry mouth
- Blurred vision
- Constipation
- Flushing (sense of warmth in the face, ears, neck and trunk)
In-Depth Precautions and Warning
Drug Warnings
Do not take Alfuzosin+solifenacin if you are allergic to Alfuzosin+solifenacin or any of the ingredients. Women or children should not take $ name. Older patients may be more sensitive to the side effects of Alfuzosin+solifenacin, especially dizziness and low blood pressure when getting up from a sitting or lying position. Do not take Alfuzosin+solifenacin if you have/had a heart attack or stroke or heart failure, low blood pressure, kidney or liver disease, have certain eye diseases, loss of vision due to loss of blood flow to the optic (eye) nerve. Consult your doctor before taking Alfuzosin+solifenacin if you are taking medicines for the treatment of hypertension (high blood pressure). If you take Alfuzosin+solifenacin with any antihypertensive medicine your blood pressure could suddenly drop to a life-threatening level. So avoid intake of Alfuzosin+solifenacin with antihypertensive drugs. You are advised not to drive or operate heavy machinery after taking Alfuzosin+solifenacin as it may cause dizziness. Avoid consuming alcohol along with Alfuzosin+solifenacin as it could lead to increased dizziness and drowsiness.
Drug Interactions
Drug-Drug Interaction: Alfuzosin+solifenacin interacts with medicines used to treat high blood pressure (prazosin, terazosin, verapamil, diltiazem, amiodarone), drugs used to treat erectile dysfunction (sildenafil, vardenafil, tadalafil), azole antifungals (itraconazole, ketoconazole), HIV protease inhibitor (lopinavir, ritonavir, indinavir), blood thinners (warfarin), antibiotics (erythromycin), NSAIDs (diclofenac, ibuprofen, indomethacin).
Drug-Food Interaction: Alfuzosin+solifenacin may interact with grapefruit juice, alcohol, and tobacco. This may cause more side effects than it normally does. So, a Alfuzosin+solifenacin should not be taken along with them.
Drug-Disease Interaction: Alfuzosin+solifenacin should not be taken in patients with heart problems, low blood pressure, kidney or liver disease, have certain eye diseases, loss of vision due to loss of blood flow to the optic (eye) nerve.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionYou are advised not to consume alcohol while taking Alfuzosin+solifenacin as it makes you pee more and can irritate your bladder and also increased dizziness and lower blood pressure.
Pregnancy
unsafeWomen should not use Alfuzosin+solifenacin as it is used to treat benign prostatic hyperplasia (BPH) in men only.
Breast Feeding
unsafeWomen should not use $ name as it is used to treat benign prostatic hyperplasia (BPH) in men only.
Driving
cautionAlfuzosin+solifenacin may cause dizziness. Therefore you are advised to drive and operate machinery only if you are alert.
Liver
cautionAlfuzosin+solifenacin should be used with caution in patients with liver disease. The dose adjustment may be needed in such patients.
Kidney
cautionAlfuzosin+solifenacin should be used with caution in patients with kidney disease. The dose adjustment may be needed in such patients.
Children
unsafeAlfuzosin+solifenacin is not recommended for children. The safety and effectiveness of Alfuzosin+solifenacin have not been established in children due to limited testing of this drug on children by competent authorities worldwide.
Habit Forming
Diet & Lifestyle Advise
- Maintaining a healthy weight, eating a balanced diet, and regular exercising may help your bladder empty at a normal rate.
- Avoid consumption of alcohol to treat your condition effectively as consuming an excessive amount of alcohol may make you pee more and can irritate your bladder.
- Limit the amount of fluids and caffeine you drink, especially before you go out or go to bed.
- Stay warm, cold can make it feel more urgent to pee.
- Avoid usage of tobacco.
- Do daily exercise to strengthen your pelvic floor muscles.
Patients Concern
Disease/Condition Glossary
Benign Prostatic Hyperplasia (BPH): is an enlargement of the prostate gland. The prostate is a small, muscular gland in the male reproductive system. It is a common condition as men get older (50-60 years). It occurs when the cells of the prostate gland begin to multiply. In an enlarged prostate gland, the bladder wall becomes thicker, and the bladder may weaken and lose the ability to empty fully, leaving some urine in the bladder. Symptoms of BPH include frequent or urgent need to urinate, nocturia (increased frequency of urination at night, difficulty starting urination, inability to empty the bladder, painful urination, blood in the urine.
FAQs
Alfuzosin+solifenacin contains Alfuzosin and Solifenacin. Alfuzosin is an alpha-blocker while Solifenacin is an antimuscarinic. Together, Alfuzosin+solifenacin works by relaxing the muscle around the bladder exit and prostate gland so urine is passed more easily. This prevents frequent, urgent or uncontrolled urination.
Yes, in some cases sexual problems (like decreased sexual interest/ability/libido, ejaculation problems, decreased sperm/semen amount), testes pain/swelling, increased breast size, or breast tenderness in the male might occur. Sexual problems in a male may be continued even after stopping the intake of Alfuzosin+solifenacin. However, if any of these side effects persist, tell your doctor promptly.
No, you are advised not to donate blood if you are taking Alfuzosin+solifenacin as it contains Dutasteride, which is carried in the blood and can cause congenital disabilities. Even if you stop taking Alfuzosin+solifenacin, wait for at least 6 months and consult your doctor before donating blood.
Alfuzosin+solifenacin is known to be harmful to men below the age of 18, childbearing women, patients with known allergy to any of the components of Alfuzosin+solifenacin.
No, Alfuzosin+solifenacin should not be taken along with blood-pressure-lowering medicines. Alfuzosin+solifenacin may cause a sudden drop in your blood pressure which could lead to dizziness or fainting. Therefore, if Alfuzosin+solifenacin is taken along with blood pressure lowering medicines, it could lead to a severe decrease in blood pressure which could be lethal.
