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Ambroxol+guaifenesin

About

Ambroxol+guaifenesin belongs to the class of medicines called ‘expectorants’ primarily used to treat cough associated with mucus. Coughing (dry or productive) is a body’s way of clearing irritants (like allergens, mucus, or smoke) from airways and preventing infection. There are two types of coughs, namely: Dry cough and chesty cough. A dry cough is tickly and doesn't produce any vicious or thick mucus, while a chesty cough (wet cough) means mucous or sputum is produced to help clear your airways.

Ambroxol+guaifenesin is a combination of two drugs: Ambroxol (mucolytic agent) and Guaifenesin (expectorant). Ambroxol belongs to the class of mucolytic agents (cough/sputum thinner) that works by thinning and loosening phlegm (mucus) in the lungs, windpipe, and nose. Guaifenesin belongs to the class of expectorants that increase the volume of fluid in the airways, reduce mucus stickiness, and remove it from airways.

Take Ambroxol+guaifenesin with or without food as advised by your doctor with the help of a measuring cup. Your doctor will recommend how often you take Ambroxol+guaifenesin based on your medical condition. Some people may experience nausea, vomiting, drowsiness, headache, dizziness, skin rash, and nervousness. Most of these side effects of Ambroxol+guaifenesin do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Ambroxol+guaifenesin or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Ambroxol+guaifenesin. Use Ambroxol+guaifenesin with caution in children if prescribed by a doctor. Drink plenty of fluids while taking Ambroxol+guaifenesin to loosen mucus. It is mandatory to inform your doctor if you have heart, liver, kidney diseases, stomach ulcers, thyroid disorders, diabetes, inflammation of air passages, lung disorders, and difficulty breathing before taking Ambroxol+guaifenesin. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Uses of Ambroxol+guaifenesin

Chesty cough

Medicinal Benefits

Ambroxol+guaifenesin is a combination of two drugs, namely: Ambroxol and Guaifenesin. Ambroxol belongs to the class of mucolytic agents (cough/sputum thinner) that works by thinning and loosening phlegm (mucus) in the lungs, windpipe, and nose for coughing out easily. Being an expectorant, Guaifenesin reduces the thickness or viscosity of bronchial secretions (phlegm) and increases mucus flow making it easier to cough. 

Directions for Use

Ambroxol+guaifenesin is available in the form of oral syrup. Take the liquid/syrup in a measuring device with or without food in a dose and duration as advised by the doctor. Keep the liquid bottle away from direct sunlight. Shake the bottle well before use. Take Ambroxol+guaifenesin regularly at a fixed time. Your doctor will decide the dose and duration of the course based on the severity of your disease. Do not stop taking Ambroxol+guaifenesin on your own until the doctor advised you to do so.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Ambroxol+guaifenesin

  • Nausea
  • Vomiting
  • Stomach upset
  • Drowsiness
  • Dizziness
  • Headache
  • Skin rash
  • Nervousness

In-Depth Precautions and Warning

Drug Warnings

If you are allergic to Ambroxol+guaifenesin or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Ambroxol+guaifenesin.If you have diabetes, regular monitoring of blood sugar levels is recommended while taking Ambroxol+guaifenesin. Drink plenty of fluids while taking Ambroxol+guaifenesin to loosen mucus and lubricate your throat. If you cough for a long time, asthma, or suffer from serious asthma attacks, liver or kidney problems, or peptic or duodenal ulcers, inform your doctor before taking Ambroxol+guaifenesin. Ambroxol in Ambroxol+guaifenesin can cause hypokalemia (low potassium levels in the blood). Therefore it should be used with caution in patients with bronchospasm (narrowed airways or bronchi with mucus). Avoid consuming alcohol with Ambroxol+guaifenesin as it could lead to increased drowsiness or dizziness. Drive only if you are alert after taking Ambroxol+guaifenesin as it may cause dizziness or drowsiness in some people.

Drug Interactions

Drug-Drug Interaction: Ambroxol+guaifenesin may interact with antibiotics (erythromycin, doxycycline, cefuroxime, amoxicillin).

Drug-Food Interaction: Ambroxol+guaifenesin may interact with caffeine. Therefore, avoid or limit the intake of caffeinated beverages, foods, or dietary supplements with Ambroxol+guaifenesin as it may increase the risk of adverse effects.

Drug-Disease Interaction: If you have diabetes, fits, overactive thyroid, stomach ulcers,  kidney, liver, or heart problems, inform your doctor before taking Ambroxol+guaifenesin.

Drug-Drug Interactions Checker List:

  • ERYTHROMYCIN
  • DOXYCYCLINE
  • CEFUROXIME
  • AMOXICILLIN
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      It is not known whether it is safe to consume alcohol with Ambroxol+guaifenesin. Please consult your doctor before using Ambroxol+guaifenesin. Avoid consuming alcohol with Ambroxol+guaifenesin as it could lead to increased drowsiness or dizziness.

    • Safety Warning

      Pregnancy

      caution

      Ambroxol+guaifenesin is a Category C pregnancy drug. There are limited studies on how Ambroxol+guaifenesin affects pregnancy. However, animal studies showed harmful effects on the developing baby. Please consult your doctor before using Ambroxol+guaifenesin if you are pregnant or planning to conceive.

    • Safety Warning

      Breast Feeding

      caution

      It is unknown whether Ambroxol+guaifenesin is excreted in human milk. Ambroxol+guaifenesin is given to breastfeeding mothers only if the doctor thinks benefits are greater than risks.

    • Safety Warning

      Driving

      caution

      Do not drive or operate machinery if you experience sleepiness, dizziness, increased/uneven heart rate, and shakiness while using Ambroxol+guaifenesin. This may affect your ability to drive. Seek medical attention if the symptoms persist longer.

    • Safety Warning

      Liver

      caution

      Ambroxol+guaifenesin should be used with caution in patients with liver diseases. Let your doctor know if you have any history of liver diseases or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing Ambroxol+guaifenesin.

    • Safety Warning

      Kidney

      caution

      Ambroxol+guaifenesin should be used with caution in patients with kidney diseases. Let your doctor know if you have any history of kidney diseases. Your doctor will weigh the benefits and potential risks before prescribing Ambroxol+guaifenesin.

    • Safety Warning

      Children

      caution

      Ambroxol+guaifenesin is not recommended for children less than two years of age. However, it can be given to the children above two years of age if prescribed by the doctor.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Take the medication as directed by the doctor and at regular intervals. Do not use other over-the-counter medications, herbal or vitamin supplements without informing your pharmacist or doctor when you take Ambroxol+guaifenesin.
    • Know your triggers like allergens, such as pollen, dust, and food items that make your asthma and other respiratory diseases severe.
    • Quit smoking and avoid passive smoking. Smoking also reduces the effectiveness of the medicine.
    • Drink warm fluids while you take Ambroxol+guaifenesin to help loosen congestion and lubricate the throat.
    • Eat a healthy diet and exercise regularly to strengthen your breathing muscles and boost your immune system.
    • Avoid dairy products such as milk as they may increase mucus production. Also, avoid processed or refined foods to have relief from cough. Instead, replace baked foods, fried foods, white bread, white pasta, French fries, sugary desserts, and chips with green leafy vegetables.
    • Avoid citrus fruits as they may worsen the cough. Eat fruits rich in water content such as pears, watermelon, peaches, and pineapples.
    • Learning breathing exercises will help you move more air in and out of your lungs.

    Special Advise

    • Regularly monitor blood sugar levels while taking Ambroxol+guaifenesin if you have diabetes, increasing blood sugar levels.
    • Guaifenesin in Ambroxol+guaifenesin can affect certain lab results; inform your doctor or laboratory staff as you take this medicine.

    Patients Concern

    Disease/Condition Glossary

    Cough: Coughing is a body’s way of clearing irritants (like allergens, mucus, or smoke) from airways and preventing infection. Coughs may be dry or productive. A productive cough (wet cough) brings up sputum (phlegm, mucus, and other matter) from the lungs. Cough is commonly caused as a response to allergy or viral infection but coughing up mucus is possibly an indication of infection in the respiratory tract. If you are coughing thick, solid white mucus, you may have a bacterial infection in the airways. If the mucus is clear or light-colored, you may have allergies or a minor infection in the respiratory tract, and yellow or green mucus indicates a respiratory infection.

    FAQs

    Ambroxol+guaifenesin contains Ambroxol and Guaifenesin. Ambroxol is a mucolytic agent (cough/sputum thinner) that thins and loosens phlegm (mucus) in the lungs. Thereby, it helps to cough out easily. Guaifenesin is an expectorant that increases the volume of fluid in the airways, reduces mucus stickiness, and helps remove it from the airways.

    Inform your doctor before taking Ambroxol+guaifenesin if you have any liver and kidney diseases, stomach ulcers, seizures (fits), thyroid disorders, diabetes, inflammation of air passages, lung disorders, and breathing difficulty.

    Yes, you may take Ambroxol+guaifenesin with antibiotics such as erythromycin, amoxicillin, doxycycline, and cefuroxime as it may increase the concentration of antibiotics in the formed mucus in airways. However, you are recommended to consult a doctor before using Ambroxol+guaifenesin with antibiotics or any other medicines.

    Ambroxol+guaifenesin should be used with caution in diabetic patients if prescribed by a doctor. However, regular monitoring of blood sugar levels is recommended while taking Ambroxol+guaifenesin as it may increase blood sugar levels.

    You are recommended to take Ambroxol+guaifenesin for as long as your doctor has prescribed it. However, if the symptoms persist or worsen with rash, fever, or persistent headache after 1 week of using Ambroxol+guaifenesin, please consult your doctor.

    Yes, Ambroxol+guaifenesin may cause drowsiness or dizziness. It is not necessary for everyone taking Ambroxol+guaifenesin to experience this side effect. Therefore, avoid driving if you feel drowsy or dizzy after taking Ambroxol+guaifenesin.

    Ambroxol+guaifenesin consists of Ambroxol which can cause hypokalaemia (low potassium levels in the blood), therefore it should be used with caution in patients with bronchospasm (narrowed airways with wheezing sound while breathing).

    Available Medicines for

    Ambroxol+guaifenesin

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