Amikacin Sulphate
About
Amikacin Sulphate belongs to the group of antibiotic medicines called aminoglycosides used to treat bacterial infections. Bacterial infection can be defined as the proliferation/multiplication of harmful strains of bacteria inside or on the body. Infectious or harmful bacteria can make you sick and reproduce quickly in your body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick.
Amikacin Sulphate works by inhibiting the production of bacterial proteins which are necessary for the survival of the bacteria. Thereby, leads to the death of the bacterial cell. Thus, Amikacin Sulphate helps treat bacterial infections.
Amikacin Sulphate will be administered by a healthcare professional. Do not self-administer. In some cases, you may experience certain common side-effects such as irritation at the site of application, skin rash, nausea, and vomiting. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.
Do not be reluctant to speak with your doctor if you experience any difficulty while taking Amikacin Sulphate. Your doctor may advise you to get urine, blood, and hearing tests before and during the treatment to check for signs of side-effects. Depending upon the results of these tests your doctor may adjust the dose of Amikacin Sulphate. You are advised to be well hydrated before and during the treatment with Amikacin Sulphate.
Uses of Amikacin Sulphate
Medicinal Benefits
Amikacin Sulphate belongs to the group of antibiotic medicines called aminoglycosides. Amikacin Sulphate is used to treat serious bacterial infections caused by bacteria. Amikacin Sulphate works by inhibiting the production of bacterial proteins which are necessary for the survival of the bacteria. Thereby, leads to the death of bacteria.
Directions for Use
Storage
Side Effects of Amikacin Sulphate
- Irritation at the site of application
- Skin rash
- Nausea
- Diarrhoea
- Vomiting
In-Depth Precautions and Warning
Drug Warnings
Do not take Amikacin Sulphate if you are allergic to any of the components, antibiotics related to aminoglycosides, sulphites, if you are suffering from a disorder called myasthenia gravis (severe weakness of muscles in the body), and dehydration. Talk to your doctor before taking Amikacin Sulphate if you have any kidney problems, or hearing problems such as tinnitus (buzzing or ringing in the ears). You are advised not to drive or operate heavy machinery after taking Amikacin Sulphate as it may cause dizziness. If you are pregnant or breastfeeding, talk to your doctor before taking Amikacin Sulphate. The doctor will prescribe you Amikacin Sulphate only if the benefits outweigh the potential risks.
Drug Interactions
Drug-Drug Interactions: Amikacin Sulphate may have interaction with water pills/diuretics (furosemide, ethacrynic acid), pain killers (indomethacin, aspirin, lidocaine), antibiotics (like penicillin, kanamycin, gentamycin, ceftriaxone, vancomycin); vitamin supplements (like thiamine), anti-cancer drugs (like cisplatin).
Drug-Food Interactions: No food interactions have been found.
Drug-Disease Interactions: Inform your doctor if you have dehydration, neuromuscular blockade (blockage of the neuromuscular transmission at the junction), ototoxicity (ear toxicity/ear dysfunction) and renal dysfunction (kidney problems).
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionYou are advised not to consume alcohol while taking Amikacin Sulphate as it may lead to unwanted side-effects.
Pregnancy
cautionAmikacin Sulphate belongs to pregnancy category-D. If you are pregnant, the doctor will prescribe Amikacin Sulphate only if the benefits outweigh the potential risks.
Breast Feeding
cautionIf you are breastfeeding, talk to your doctor before taking Amikacin Sulphate. The doctor will prescribe Amikacin Sulphate only if the benefits outweigh the potential risks.
Driving
cautionAmikacin Sulphate may cause dizziness, therefore you are advised to drive and operate machinery only if you are alert.
Liver
safe if prescribedAmikacin Sulphate is safe to be used in people with liver problems if prescribed by a doctor.
Kidney
cautionAmikacin Sulphate should be used with caution in patients with kidney disease. Dose adjustment may be needed in such patients.
Children
safe if prescribedAmikacin Sulphate can be given to children if prescribed by the doctor. Dose adjustment may be required as per the age and weight of the child.
Habit Forming
Diet & Lifestyle Advise
- Antibiotics can alter the useful bacteria in the stomach which help in digestion. Therefore, you are advised to take foods rich in probiotics such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto and cheese.
- Eat fibre-rich food such as whole grains, beans, lentils, berries, broccoli, peas and bananas.
- Avoid foods rich in calcium, grapefruit and grapefruit juice as they might hinder the absorption of antibiotics.
- Avoid consumption of alcohol and usage of tobacco.
Special Advise
Patients Concern
Disease/Condition Glossary
Bacterial infections: It is the proliferation/multiplication of harmful strains of bacteria inside or on the body. The general signs and symptoms of bacterial infections include fever, tiredness, headache, nausea, vomiting, and swollen lymph nodes in the neck, armpits and groin.
FAQs
Amikacin Sulphate belongs to the group of antibiotic medicines called as aminoglycosides. Amikacin Sulphate is used to treat serious bacterial infections. Amikacin Sulphate works by inhibiting the production of bacterial proteins which are necessary for the existence of the bacteria. Thereby, leads to the death of bacteria.
Yes, Amikacin Sulphate may lead to changes in kidney function. Your doctor will advise you to get blood and urine tests to evaluate the levels of protein or white/red blood cells and creatinine or nitrogen in blood samples. Amikacin Sulphate should be used with caution in patients with kidney disease. Dose adjustment may be needed in such patients.
Yes, Amikacin Sulphate may cause dizziness. You are advised not to drive or operate heavy machinery after taking Amikacin Sulphate as it may cause dizziness and can affect vision. Drive or operate machinery only if you are alert.
Yes, antibiotics may cause diarrhoea. Include foods containing probiotics such as yoghurt, cheese, and buttermilk in your diet as it would help in proper digestion. Also, eat fibre-rich food like whole grain, beans, peas, and bananas. Consult your doctor if you have severe diarrhoea. Do not take any anti-diarrheal medicine without consulting your doctor.
